Hotels in 50381 - Des Moines IA

Only hotels in 50381 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50381 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

50381 Hotels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1000 Walnut St., Des Moines, IA 50309 +1-888-389-4121 ~0.49 miles east of 50381
  • High-end Downtown hotel
  • 5 meeting rooms in hotel
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From$149
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Des Moines Downtown in Des Moines
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
333 SW 11th St., Des Moines, IA 50309 +1-888-675-2083 ~0.60 miles east of 50381
  • Mid-scale Downtown property
  • Fitness / Gym is on-site
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From$99
Very Good 4.5 /5 Reviews Call BookMore Details
Des Lux Hotel in Des Moines
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
800 Locust St., Des Moines, IA 50309 +1-800-716-8490 ~0.64 miles east of 50381
  • 3-star Downtown hotel
  • Hotel has 3 meeting rooms
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From$179
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Des Moines Marriott Downtown
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
700 Grand Ave., Des Moines, IA 50309 +1-800-805-5223 ~0.69 miles east of 50381
  • Expensive Downtown hotel
  • 15 meeting rooms in property
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From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hyatt Place Des Moines / Downtown
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
418 6th Ave., Des Moines, IA 50309 +1-888-965-1860 ~0.75 miles east of 50381
  • 4 star Downtown property
  • 4 meeting rooms in property
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Surety Hotel
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
206 6th Ave., Des Moines, IA 50309 +1-888-788-5576 ~0.76 miles east of 50381
  • 3 star property
  • 50 sleeping rooms in hotel
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From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Hyatt Place Des Moines Downtown
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
418 6th Ave., Des Moines, IA 50309 +1-888-897-9207 ~0.76 miles east of 50381
  • Affordable Downtown property
  • Hotel has 7 floors
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From$93
Very Good 4.5 /5 Reviews Call BookMore Details
Renaissance Des Moines Savery Hotel - Des Moines
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
401 Locust St., Des Moines, IA 50309 +1-888-311-4278 ~0.88 miles east of 50381
  • Affordable hotel
  • Hotel has 12 floors
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From$149
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hilton Des Moines Downtown
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
435 Park St., Des Moines, IA 50309 +1-888-469-4795 ~0.95 miles northeast of 50381
  • Four-star hotel
  • 8 meeting rooms in property
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From$99
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Residence Inn Des Moines Downtown
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
100 SW Water St., Des Moines, IA 50309 +1-888-734-9421 ~1.13 miles east of 50381
  • Three Star Downtown property
  • Free complimentary breakfast
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From$99
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Downtown - Mercy Area by IHG : 1050 6th Ave.
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1050 6th Ave., Des Moines, IA 50314 +1-888-841-5292 ~1.13 miles northeast of 50381
  • Midscale Downtown property
  • 12 meeting rooms in property
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From$65
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Des Moines Downtown in Des Moines
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
120 SW Water St., Des Moines, IA 50309 +1-888-455-5160 ~1.13 miles east of 50381
  • Midscale Downtown hotel
  • Fitness / Gym is on-site
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From$98
Very Good 4.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
207 Crocker St., Des Moines, IA 50309 +1-888-965-8297 ~1.19 miles northeast of 50381
  • Low priced Downtown hotel
  • Gym / Fitness Center Available
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From$129
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express Des Moines, an IHG Hotel in Des Moines
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1140 24t St., Des Moines, IA 50311 +1-888-906-6358 ~1.23 miles northwest of 50381
  • Cheap Suburban property
  • Hotel has 52 rooms
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From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Event Center : 929 3rd St. Des Moines Ia 50309
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309 +1-888-749-6785 ~1.23 miles northeast of 50381
  • Inexpensive Downtown hotel
  • Free complimentary breakfast
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From$120
Very Good 4.0 /5 Read Reviews Call BookMore Details
Embassy Suites Hotel Des Moines Downtown : 101 East Locust St.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
101 East Locust St., Des Moines, IA 50309 +1-888-878-9982 ~1.26 miles east of 50381
  • 3 star Downtown property
  • Hotel has 234 rooms
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From$75
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Staybridge Suites Des Moines Downtown - Des Moines
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
201 East Locust St., Des Moines, IA 50309 +1-888-389-4485 ~1.33 miles east of 50381
  • Affordable Downtown property
  • 5 floors in property
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites Des Moines at Drake University : 2650 University Ave.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2650 University Ave., Des Moines, IA 50311 +1-888-389-4121 ~1.37 miles northwest of 50381
  • Midscale Downtown hotel
  • Gym is available on property
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From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
AC Hotel Des Moines East Village : 401 East Grand Ave.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
401 East Grand Ave., Des Moines, IA 50309 +1-888-675-2083 ~1.45 miles east of 50381
  • Three Star Downtown property
  • 3 meeting rooms in hotel
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From$129
Very Good 4.0 /5 Review Score Call BookMore Details
Motel 6 Des Moines Sou Airport
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4817 Fleur Dr., Des Moines, IA 50321 +1-800-716-8490 ~2.98 miles south of 50381
  • Low-priced property
  • Check-in: 15:00
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From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Des Moines-Airport : 5001 Fleur Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
5001 Fleur Dr., Des Moines, IA 50321 +1-800-805-5223 ~3.10 miles south of 50381
  • Three Star Airport hotel
  • Check-in: 3:00 pm
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From$69
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1901 Hackley Ave., Des Moines, IA 50315 +1-888-965-1860 ~3.11 miles south of 50381
  • Two-star Airport property
  • Check in time: 3:00 PM
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From$64
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Americinn by Wyndham Des Moines Airport in Des Moines
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1920 Hackley Ave., Des Moines, IA 50315 +1-888-788-5576 ~3.16 miles south of 50381
  • Low-priced Airport hotel
  • 2 floors in hotel
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From$65
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Des Moines Airport in Des Moines
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
5231 Fleur Dr., Des Moines, IA 50321 +1-888-897-9207 ~3.23 miles south of 50381
  • Mid-scale Airport property
  • 2 floors in property
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Des Moines-Airport/Conf Center by IHG : 6111 Fleur Dr.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6111 Fleur Dr., Des Moines, IA 50321 +1-888-311-4278 ~3.77 miles south of 50381
  • Midscale Airport property
  • Check in: 3:00 PM
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From$108
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham West Des Moines
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1258 8th St., West Des Moines, IA 50265 +1-888-469-4795 ~3.86 miles west of 50381
  • Cheap Suburban property
  • 2 floors in hotel
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From$50
Average 3.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1810 Army Post Rd., Des Moines, IA 50315 +1-888-734-9421 ~4.00 miles south of 50381
  • Midscale Airport hotel
  • 2 floors in hotel
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Hilton Garden Inn Des Moines Airport in Des Moines
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
6800 Fleur Dr., Des Moines, IA 50321 +1-888-841-5292 ~4.23 miles south of 50381
  • Three Star Airport property
  • 3 meeting rooms in hotel
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From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Fairgrounds in Des Moines
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
410 East 30th St., Des Moines, IA 50317 +1-888-455-5160 ~4.24 miles east of 50381
  • Economy Rural property
  • Hotel has 19 suites
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From$50
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Airport - Des Moines
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
6880 Fleur Dr., Des Moines, IA 50321 +1-888-965-8297 ~4.27 miles south of 50381
  • Affordable Airport property
  • Complimentary breakfast is offered
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From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Des Moines Airport
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
7201 SW 22nd St., Des Moines, IA 50321 +1-888-906-6358 ~4.48 miles south of 50381
  • 3-star Airport hotel
  • Shuttle to airport available
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Des Moines North
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-749-6785 ~4.74 miles northeast of 50381
  • Two-star Highway property
  • 2 floors in property
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From$55
Average 3.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Des Moines North
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-878-9982 ~4.75 miles northeast of 50381
  • Economy Highway property
  • 2 conference rooms in property
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From$50
Poor 2.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Des Moines - Des Moines
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
4685 a Northeast 14th St., Des Moines, IA 50313 +1-888-389-4485 ~4.75 miles northeast of 50381
  • Economy Highway hotel
  • 2 floors in hotel
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From$54
Very Good 4.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Des Moines Airport
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
6221 Willow Creek Ave., Des Moines, IA 50321 +1-888-389-4121 ~5.03 miles southwest of 50381
  • 2 star Airport property
  • Check-in: 3:00 PM
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From$62
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
4950 NE 14th St., Des Moines, IA 50313 +1-888-675-2083 ~5.04 miles northeast of 50381
  • Mid-scale Highway property
  • Check-in time: 3:00
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From$57
Average 3.5 /5 Review Score Call BookMore Details
Red Roof Inn Des Moines
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5020 NE 14th St., Des Moines, IA 50313 +1-800-716-8490 ~5.06 miles northeast of 50381
  • Inexpensive Highway hotel
  • 51 rooms in hotel
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From$60
Poor 2.0 /5 Review Score Call BookMore Details
Motel 6 Des Moines, IA - North
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
4940 NE 14th St., Des Moines, IA 50313 +1-800-805-5223 ~5.07 miles northeast of 50381
  • Economical hotel
  • 2 floors in hotel
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From$60
Poor 2.5 /5 Hotel Reviews Call BookMore Details
Sonesta Essential Des Moines in Des Moines
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
4755 Merle Hay Rd., Des Moines, IA 50322 +1-888-965-1860 ~5.30 miles northwest of 50381
  • Cheap Highway hotel
  • Hotel has 12 suites
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Extended Stay America Select Suites - Des Moines - West Des Moine in West Des Moines
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2701 Westown Pkwy., West Des Moines, IA 50266 +1-888-788-5576 ~5.36 miles west of 50381
  • Economy hotel
  • Access to gym on-site
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From$59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
4845 Merle Hay Rd., Des Moines, IA 50322 +1-888-897-9207 ~5.38 miles northwest of 50381
  • Two-star Highway hotel
  • Check in: 3:00
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From$55
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Urbandale/Des Moines Area : 5900 Sutton Pl
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
5900 Sutton Pl, Urbandale, IA 50322 +1-888-311-4278 ~5.49 miles northwest of 50381
  • Low-priced Suburban hotel
  • Comp. Breakfast
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From$45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
4800 Merle Hay Rd., Des Moines, IA 50322 +1-888-469-4795 ~5.51 miles northwest of 50381
  • Three Star Suburban hotel
  • Hotel has 5 floors
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From$89
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road : 4995 Merle Hay Rd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50310 +1-888-734-9421 ~5.52 miles northwest of 50381
  • Economy hotel
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50322 +1-888-841-5292 ~5.54 miles northwest of 50381
  • Affordable property
  • Check in: 3:00PM
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From$62
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Ramada by Wyndham Des Moines Tropics Resort & Conference Center
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
5000 Merle Hay Rd., Des Moines, IA 50322 +1-888-455-5160 ~5.58 miles northwest of 50381
  • Mid-scale Suburban hotel
  • Access to gym on-site
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From$79
Average 3.0 /5 Reviews Call BookMore Details
Americinn by Wyndham Johnston Des Moines
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
5050 Merle Hay Rd., Johnston, IA 50131 +1-888-965-8297 ~5.82 miles northwest of 50381
  • Cheap Highway hotel
  • Hotel has 14 suites
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From$64
Very Good 4.0 /5 Read Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Urbandale / Des Moines
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
8711 Plum Dr., Urbandale, IA 50322 +1-888-906-6358 ~6.86 miles northwest of 50381
  • Two-star Highway hotel
  • 25 suites in property
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Des Moines Urbandale
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8661 Plum Dr., Urbandale, IA 50322 +1-888-749-6785 ~6.87 miles northwest of 50381
  • 3 star Suburban property
  • Fitness / Gym is on-site
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From$84
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Grandstay Hotel & Suites in Johnston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
6215 Merle Hay Rd., Johnston, IA 50131 +1-888-878-9982 ~6.88 miles northwest of 50381
  • Two star Highway property
  • Gym / Fitness Center Available
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
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