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50381 Hotels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton : 1000 Walnut St.
+1-888-389-4121
1000 Walnut St., Des Moines, IA 50309 ~0.49 miles east of 50381
  • High end Downtown property
  • Check in time: 4:00 PM
From$149
Average 3.0 /5 Read Reviews Call BookMore Details
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Holiday Inn Express & Suites Des Moines Downtown : 333 SW 11th St.
+1-888-675-2083
333 SW 11th St., Des Moines, IA 50309 ~0.60 miles east of 50381
  • Midscale Downtown property
  • Hotel has an eco-friendly policy Read more
From$99
Very Good 4.5 /5 Reviews Call BookMore Details
Des Lux Hotel - Des Moines
+1-800-716-8490
800 Locust St., Des Moines, IA 50309 ~0.64 miles east of 50381
  • Affordable Downtown hotel
  • Access to gym on-site
From$179
Very Good 4.0 /5 Read Reviews Call BookMore Details
Des Moines Marriott Downtown
+1-800-805-5223
700 Grand Ave., Des Moines, IA 50309 ~0.69 miles east of 50381
  • Expensive Downtown hotel
  • Gym / Fitness Center Available
From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hyatt Place Des Moines Downtown
+1-888-965-1860
418 6th Ave., Des Moines, IA 50309 ~0.75 miles east of 50381
  • 3-star Downtown hotel
  • 6 suites in property
From$144
Average 3.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Des Moines/Downtown - Des Moines
+1-888-788-5576
418 6th Ave., Des Moines, IA 50309 ~0.75 miles east of 50381
  • Four-star Downtown hotel
  • Free complimentary breakfast
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Surety Hotel : 206 6th Ave.
+1-888-897-9207
206 6th Ave., Des Moines, IA 50309 ~0.76 miles east of 50381
  • Three Star property
  • 50 rooms in property
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Renaissance Des Moines Savery Hotel
+1-888-311-4278
401 Locust St., Des Moines, IA 50309 ~0.88 miles east of 50381
  • Affordable property
  • Hotel has 12 floors
From$149
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton Des Moines Downtown : 435 Park St.
+1-888-469-4795
435 Park St., Des Moines, IA 50309 ~0.95 miles northeast of 50381
  • Expensive property
  • Access to gym on-site
From$99
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Residence Inn Des Moines Downtown - Des Moines
+1-888-734-9421
100 SW Water St., Des Moines, IA 50309 ~1.13 miles east of 50381
  • Mid-scale Downtown hotel
  • Has environment-friendly policy See policy
From$99
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Downtown Mercy Area An Ihg Hotel - Des Moines
+1-888-841-5292
1050 6th Ave., Des Moines, IA 50314 ~1.13 miles northeast of 50381
  • Midscale Downtown property
  • Fitness + Health Center
From$65
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Des Moines Downtown : 120 SW Water St.
+1-888-455-5160
120 SW Water St., Des Moines, IA 50309 ~1.13 miles east of 50381
  • Affordable Downtown hotel
  • Free complimentary breakfast
From$98
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown - Des Moines
+1-888-965-8297
207 Crocker St., Des Moines, IA 50309 ~1.19 miles northeast of 50381
  • 2 star Downtown hotel
  • Check-in: 3:00pm
From$129
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Des Moines, an IHG Hotel
+1-888-906-6358
1140 24t St., Des Moines, IA 50311 ~1.23 miles northwest of 50381
  • Cheap Suburban hotel
  • 2 floors in hotel
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Event Center - Des Moines
+1-888-749-6785
929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309 ~1.23 miles northeast of 50381
  • Economical Downtown property
  • Check in: 3:00PM
From$120
Very Good 4.0 /5 Review Score Call BookMore Details
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Embassy Suites Hotel Des Moines Downtown : 101 East Locust St.
+1-888-878-9982
101 East Locust St., Des Moines, IA 50309 ~1.26 miles east of 50381
  • Mid-scale Downtown property
  • 6 meeting rooms in hotel
From$75
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Staybridge Suites Des Moines Downtown - Des Moines
+1-888-389-4485
201 East Locust St., Des Moines, IA 50309 ~1.33 miles east of 50381
  • Midscale Downtown hotel
  • 111 suites in hotel
From$99
Very Good 4.5 /5 Reviews Call BookMore Details
Home2 Suites Des Moines at Drake University in Des Moines
+1-888-389-4121
2650 University Ave., Des Moines, IA 50311 ~1.37 miles northwest of 50381
  • Affordable Downtown hotel
  • Check in: 3:00 PM
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
AC Hotel Des Moines East Village
+1-888-675-2083
401 East Grand Ave., Des Moines, IA 50309 ~1.45 miles east of 50381
  • 3 star Downtown property
  • Check in time: 3:00PM
From$129
Very Good 4.0 /5 Read Reviews Call BookMore Details
Motel 6 Des Moines Sou Airport
+1-800-716-8490
4817 Fleur Dr., Des Moines, IA 50321 ~2.98 miles south of 50381
  • Inexpensive property
  • Check-in: 15:00
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Des Moines Airport
+1-800-805-5223
5001 Fleur Dr., Des Moines, IA 50321 ~3.10 miles south of 50381
  • Affordable Airport property
  • Airport shuttle provided
From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport
+1-888-965-1860
1901 Hackley Ave., Des Moines, IA 50315 ~3.11 miles south of 50381
  • Cheap Airport hotel
  • 133 rooms in property
From$64
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Americinn by Wyndham Des Moines Airport - Des Moines
+1-888-788-5576
1920 Hackley Ave., Des Moines, IA 50315 ~3.16 miles south of 50381
  • Two star Airport hotel
  • Shuttle to airport available
From$65
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Des Moines Airport - Des Moines
+1-888-897-9207
5231 Fleur Dr., Des Moines, IA 50321 ~3.23 miles south of 50381
  • Affordable Airport hotel
  • Shuttle from airport available
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Des Moines-Airport/Conf Center, an IHG Hotel
+1-888-311-4278
6111 Fleur Dr., Des Moines, IA 50321 ~3.77 miles south of 50381
  • Midscale Airport property
  • Shuttle from airport available
From$108
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham West Des Moines in West Des Moines
+1-888-469-4795
1258 8th St., West Des Moines, IA 50265 ~3.86 miles west of 50381
  • Cheap Suburban property
  • Hotel has 2 floors
From$50
Average 3.0 /5 Latest Reviews Call BookMore Details
Clarion Inn in Des Moines
+1-888-734-9421
1810 Army Post Rd., Des Moines, IA 50315 ~4.00 miles south of 50381
  • 3 star Airport hotel
  • Shuttle to airport available
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Des Moines Airport
+1-888-841-5292
6800 Fleur Dr., Des Moines, IA 50321 ~4.23 miles south of 50381
  • Mid-scale Airport property
  • Hotel has a green policy See policy
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Inn & Suites Fairgrounds in Des Moines
+1-888-455-5160
410 East 30th St., Des Moines, IA 50317 ~4.24 miles east of 50381
  • Two-star Rural property
  • 3 floors in hotel
From$50
Average 3.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Airport
+1-888-965-8297
6880 Fleur Dr., Des Moines, IA 50321 ~4.27 miles south of 50381
  • 3 star Airport property
  • 82 sleeping rooms in hotel
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Des Moines Airport
+1-888-906-6358
7201 SW 22nd St., Des Moines, IA 50321 ~4.48 miles south of 50381
  • 3-star Airport property
  • Hotel has 4 floors
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Des Moines North in Des Moines
+1-888-749-6785
4685 NE 14th St., Des Moines, IA 50313 ~4.74 miles northeast of 50381
  • Low Cost Highway property
  • Fitness + Health Center
From$55
Average 3.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Des Moines North : 4685 NE 14th St.
+1-888-878-9982
4685 NE 14th St., Des Moines, IA 50313 ~4.75 miles northeast of 50381
  • Low-priced Highway property
  • 6 suites in hotel
Super 8 by Wyndham Des Moines : 4685 a Northeast 14th St.
+1-888-389-4485
4685 a Northeast 14th St., Des Moines, IA 50313 ~4.75 miles northeast of 50381
  • Low Cost Highway property
  • Free comp. breakfast
From$54
Very Good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Des Moines Airport
+1-888-389-4121
6221 Willow Creek Ave., Des Moines, IA 50321 ~5.03 miles southwest of 50381
  • Two star Airport hotel
  • Fitness center on property
From$62
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn in Des Moines
+1-888-675-2083
4950 NE 14th St., Des Moines, IA 50313 ~5.04 miles northeast of 50381
  • 3 star Highway property
  • 3 floors in property
From$57
Average 3.5 /5 Recent Reviews Call BookMore Details
Red Roof Inn Des Moines - Des Moines
+1-800-716-8490
5020 NE 14th St., Des Moines, IA 50313 ~5.06 miles northeast of 50381
  • Cheap Highway property
  • 51 rooms in property
Motel 6 Des Moines, IA - North - Des Moines
+1-800-805-5223
4940 NE 14th St., Des Moines, IA 50313 ~5.07 miles northeast of 50381
  • Inexpensive hotel
  • Check-in time: 14:00
Sonesta Essential Des Moines in Des Moines
+1-888-965-1860
4755 Merle Hay Rd., Des Moines, IA 50322 ~5.30 miles northwest of 50381
  • 2-star Highway hotel
  • Hotel has 4 floors
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Select Suites - Des Moines - West Des Moine - West Des Moines
+1-888-788-5576
2701 Westown Pkwy., West Des Moines, IA 50266 ~5.36 miles west of 50381
  • Two-star property
  • 3 floors in hotel
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay : 4845 Merle Hay Rd.
+1-888-897-9207
4845 Merle Hay Rd., Des Moines, IA 50322 ~5.38 miles northwest of 50381
  • Inexpensive Highway property
  • 76 sleeping rooms in hotel
From$55
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Urbandale/Des Moines Area
+1-888-311-4278
5900 Sutton Pl, Urbandale, IA 50322 ~5.49 miles northwest of 50381
  • 2-star Suburban hotel
  • Free complimentary breakfast
From$45
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel in Des Moines
+1-888-469-4795
4800 Merle Hay Rd., Des Moines, IA 50322 ~5.51 miles northwest of 50381
  • 3 star Suburban hotel
  • 198 rooms in property
From$89
Very Good 4.0 /5 Review Score Call BookMore Details
Quality Inn & Suites
+1-888-734-9421
4995 Merle Hay Rd., Des Moines, IA 50310 ~5.52 miles northwest of 50381
  • Inexpensive hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road in Des Moines
+1-888-841-5292
4995 Merle Hay Rd., Des Moines, IA 50322 ~5.54 miles northwest of 50381
  • 3-star hotel
  • 111 sleeping rooms in hotel
From$62
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Ramada by Wyndham Des Moines Tropics Resort & Conference Center
+1-888-455-5160
5000 Merle Hay Rd., Des Moines, IA 50322 ~5.58 miles northwest of 50381
  • Midscale Suburban hotel
  • Access to gym on-site
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Americinn by Wyndham Johnston Des Moines
+1-888-965-8297
5050 Merle Hay Rd., Johnston, IA 50131 ~5.82 miles northwest of 50381
  • Two star Highway hotel
  • 14 suites in hotel
From$64
Very Good 4.0 /5 Read Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Urbandale / Des Moines : 8711 Plum Dr.
+1-888-906-6358
8711 Plum Dr., Urbandale, IA 50322 ~6.86 miles northwest of 50381
  • Low-priced Highway hotel
  • Free comp. breakfast
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites Des Moines Urbandale
+1-888-749-6785
8661 Plum Dr., Urbandale, IA 50322 ~6.87 miles northwest of 50381
  • 3-star Suburban hotel
  • 89 rooms in hotel
From$84
Very Good 4.0 /5 Read Reviews Call BookMore Details
Grandstay Hotel & Suites in Johnston
+1-888-878-9982
6215 Merle Hay Rd., Johnston, IA 50131 ~6.88 miles northwest of 50381
  • 2 star Highway hotel
  • Free breakfast available
From$60
Average 3.0 /5 Review Score Call BookMore Details

Next: Show All Available 50381 Hotels with Pricing

Graph: Upcoming 20 Days of 50381 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Des Moines, IA discounts available. The chart reflects the cheapest Des Moines hotel for each day and each star rating category.

FAQs about hotels near 50381

What are the best rated hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Hilton Des Moines Downtown and Staybridge Suites Des Moines Downtown are the best rated hotels based on customer reviews in the last 365 days.

What are the most up-scale hotels near 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Des Moines Marriott Downtown and Hyatt Place Des Moines are the top 3 luxury hotels near 50381.

What hotels are closest to the area of 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Holiday Inn Express & Suites Des Moines Downtown, and Des Lux Hotel are the properties closest to 50381.

How much does a cheap hotel near 50381 cost per night?

In the last year, a 2 star hotel near 50381 can be as cheap as $104.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 50381 cost per night?

In the last year, the average 3 star hotel near 50381 has been $131.55 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 50381 cost?

In the last year, the average 4 star hotel near 50381 has been $142.64 per night. (based on HotelPlanner prices)

What are the best independent hotels near 50381?

Des Lux Hotel and Surety Hotel are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 50381?

Des Moines Marriott Downtown, Fairfield Inn & Suites by Marriott Des Moines Airport and Fairfield Inn & Suites Des Moines Urbandale are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 50381?

Comfort Inn & Suites Event Center, Quality Inn & Suites Des Moines Airport and Quality Inn & Suites Des Moines - Merle Hay Road are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Staybridge Suites Des Moines Downtown and Holiday Inn Downtown Mercy Area An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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