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50381 Hotels, Motels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton
+1-888-389-4121
1000 Walnut St., Des Moines, IA 50309 ~0.49 miles east of 50381
  • High-end Downtown property
  • 10 suites in hotel
From$149
Average 3.0 /5 Recent Reviews Call BookMore Details
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Holiday Inn Express & Suites Des Moines Downtown - Des Moines
+1-888-675-2083
333 SW 11th St., Des Moines, IA 50309 ~0.60 miles east of 50381
  • 3 star Downtown hotel
  • Shuttle to airport available
From$99
Very Good 4.5 /5 Read Reviews Call BookMore Details
Des Lux Hotel - Des Moines
+1-800-716-8490
800 Locust St., Des Moines, IA 50309 ~0.64 miles east of 50381
  • Three Star Downtown hotel
  • Free breakfast
From$179
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Des Moines Marriott Downtown - Des Moines
+1-800-805-5223
700 Grand Ave., Des Moines, IA 50309 ~0.69 miles east of 50381
  • High-end Downtown property
  • 6 suites in property
From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hyatt Place Des Moines Downtown
+1-888-965-1860
418 6th Ave., Des Moines, IA 50309 ~0.75 miles east of 50381
  • Midscale Downtown property
  • Airport shuttle provided
From$144
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Des Moines / Downtown : 418 6th Ave.
+1-888-788-5576
418 6th Ave., Des Moines, IA 50309 ~0.75 miles east of 50381
  • Four star Downtown property
  • Check in time: 3:00p
From$75
Average 3.0 /5 Review Score Call BookMore Details
Surety Hotel : 206 6th Ave.
+1-888-897-9207
206 6th Ave., Des Moines, IA 50309 ~0.76 miles east of 50381
  • Midscale property
  • Gym / Fitness Center Available
From$90
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Renaissance Des Moines Savery Hotel
+1-888-311-4278
401 Locust St., Des Moines, IA 50309 ~0.88 miles east of 50381
  • 3 star hotel
  • Check-in: 4:00pm
From$149
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hilton Des Moines Downtown
+1-888-469-4795
435 Park St., Des Moines, IA 50309 ~0.95 miles northeast of 50381
  • Four-star hotel
  • 330 sleeping rooms in hotel
From$99
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Residence Inn Des Moines Downtown
+1-888-734-9421
100 SW Water St., Des Moines, IA 50309 ~1.13 miles east of 50381
  • Mid-scale Downtown property
  • Hotel has 5 floors
From$99
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Downtown Mercy Area An Ihg Hotel - Des Moines
+1-888-841-5292
1050 6th Ave., Des Moines, IA 50314 ~1.13 miles northeast of 50381
  • Midscale Downtown property
  • Shuttle to airport available
From$65
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Des Moines Downtown in Des Moines
+1-888-455-5160
120 SW Water St., Des Moines, IA 50309 ~1.13 miles east of 50381
  • 3 star Downtown property
  • Check in time: 03:00pm
From$98
Very Good 4.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown : 207 Crocker St.
+1-888-965-8297
207 Crocker St., Des Moines, IA 50309 ~1.19 miles northeast of 50381
  • 2-star Downtown property
  • 91 sleeping rooms in hotel
From$129
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express Des Moines, an IHG Hotel
+1-888-906-6358
1140 24t St., Des Moines, IA 50311 ~1.23 miles northwest of 50381
  • Low-priced Suburban hotel
  • Check-in: 3:00 PM
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Event Center - Des Moines
+1-888-749-6785
929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309 ~1.23 miles northeast of 50381
  • Inexpensive Downtown property
  • Free breakfast
From$120
Very Good 4.0 /5 Recent Reviews Call BookMore Details
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Embassy Suites Hotel Des Moines Downtown - Des Moines
+1-888-878-9982
101 East Locust St., Des Moines, IA 50309 ~1.26 miles east of 50381
  • 3 star Downtown property
  • Check in: 3:00 PM
From$75
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Des Moines Downtown - Des Moines
+1-888-389-4485
201 East Locust St., Des Moines, IA 50309 ~1.33 miles east of 50381
  • 3 star Downtown property
  • 111 rooms in property
From$99
Very Good 4.5 /5 Reviews Call BookMore Details
Home2 Suites Des Moines at Drake University
+1-888-389-4121
2650 University Ave., Des Moines, IA 50311 ~1.37 miles northwest of 50381
  • 3 star Downtown hotel
  • 124 rooms in property
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
AC Hotel Des Moines East Village : 401 East Grand Ave.
+1-888-675-2083
401 East Grand Ave., Des Moines, IA 50309 ~1.45 miles east of 50381
  • 3-star Downtown property
  • Check in: 3:00PM
From$129
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Motel 6 Des Moines Sou Airport in Des Moines
+1-800-716-8490
4817 Fleur Dr., Des Moines, IA 50321 ~2.98 miles south of 50381
  • Economy property
  • Hotel has 2 floors
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Des Moines-Airport : 5001 Fleur Dr.
+1-800-805-5223
5001 Fleur Dr., Des Moines, IA 50321 ~3.10 miles south of 50381
  • Midscale Airport property
  • Access to gym on-site
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport : 1901 Hackley Ave.
+1-888-965-1860
1901 Hackley Ave., Des Moines, IA 50315 ~3.11 miles south of 50381
  • Cheap Airport hotel
  • Airport shuttle provided
From$64
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Americinn by Wyndham Des Moines Airport
+1-888-788-5576
1920 Hackley Ave., Des Moines, IA 50315 ~3.16 miles south of 50381
  • Cheap Airport hotel
  • Comp. Breakfast
From$65
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Des Moines Airport : 5231 Fleur Dr.
+1-888-897-9207
5231 Fleur Dr., Des Moines, IA 50321 ~3.23 miles south of 50381
  • Three Star Airport property
  • 2 floors in property
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Des Moines-Airport/Conf Center, an IHG Hotel in Des Moines
+1-888-311-4278
6111 Fleur Dr., Des Moines, IA 50321 ~3.77 miles south of 50381
  • Three Star Airport property
  • Airport shuttle available
From$108
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham West Des Moines : 1258 8th St.
+1-888-469-4795
1258 8th St., West Des Moines, IA 50265 ~3.86 miles west of 50381
  • 2 star Suburban hotel
  • Free breakfast available
From$50
Average 3.0 /5 Guest Reviews Call BookMore Details
Clarion Inn - Des Moines
+1-888-734-9421
1810 Army Post Rd., Des Moines, IA 50315 ~4.00 miles south of 50381
  • 3-star Airport property
  • Fitness + Health Center
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn Des Moines Airport : 6800 Fleur Dr.
+1-888-841-5292
6800 Fleur Dr., Des Moines, IA 50321 ~4.23 miles south of 50381
  • 3 star Airport hotel
  • Hotel has an eco-friendly policy See policy
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Econo Lodge Inn & Suites Fairgrounds
+1-888-455-5160
410 East 30th St., Des Moines, IA 50317 ~4.24 miles east of 50381
  • Low-priced Rural property
  • Free complimentary breakfast
From$50
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Airport : 6880 Fleur Dr.
+1-888-965-8297
6880 Fleur Dr., Des Moines, IA 50321 ~4.27 miles south of 50381
  • Three Star Airport hotel
  • Check in: 15:00
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Des Moines Airport in Des Moines
+1-888-906-6358
7201 SW 22nd St., Des Moines, IA 50321 ~4.48 miles south of 50381
  • Mid-scale Airport hotel
  • 4 floors in hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Des Moines North in Des Moines
+1-888-749-6785
4685 NE 14th St., Des Moines, IA 50313 ~4.74 miles northeast of 50381
  • Two star Highway property
  • 64 rooms in property
From$55
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Des Moines North
+1-888-878-9982
4685 NE 14th St., Des Moines, IA 50313 ~4.75 miles northeast of 50381
  • Low priced Highway property
  • 6 suites in property
Super 8 by Wyndham Des Moines - Des Moines
+1-888-389-4485
4685 a Northeast 14th St., Des Moines, IA 50313 ~4.75 miles northeast of 50381
  • 2 star Highway property
  • 64 rooms in hotel
From$54
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Des Moines Airport
+1-888-389-4121
6221 Willow Creek Ave., Des Moines, IA 50321 ~5.03 miles southwest of 50381
  • Low priced Airport hotel
  • Free comp. breakfast
From$62
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn
+1-888-675-2083
4950 NE 14th St., Des Moines, IA 50313 ~5.04 miles northeast of 50381
  • Affordable Highway property
  • Free comp. breakfast
From$57
Average 3.5 /5 Guest Reviews Call BookMore Details
Red Roof Inn Des Moines in Des Moines
+1-800-716-8490
5020 NE 14th St., Des Moines, IA 50313 ~5.06 miles northeast of 50381
  • Inexpensive Highway property
  • Hotel has an eco-friendly policy Read more
Motel 6 Des Moines, IA - North - Des Moines
+1-800-805-5223
4940 NE 14th St., Des Moines, IA 50313 ~5.07 miles northeast of 50381
  • Low-priced hotel
  • Check in: 14:00
Sonesta Essential Des Moines - Des Moines
+1-888-965-1860
4755 Merle Hay Rd., Des Moines, IA 50322 ~5.30 miles northwest of 50381
  • Low Cost Highway property
  • Has environment-friendly policy See more
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Select Suites - Des Moines - West Des Moine : 2701 Westown Pkwy.
+1-888-788-5576
2701 Westown Pkwy., West Des Moines, IA 50266 ~5.36 miles west of 50381
  • Two-star hotel
  • Hotel has 3 floors
From$59
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay : 4845 Merle Hay Rd.
+1-888-897-9207
4845 Merle Hay Rd., Des Moines, IA 50322 ~5.38 miles northwest of 50381
  • Low priced Highway hotel
  • Check in time: 3:00
From$55
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Urbandale/Des Moines Area
+1-888-311-4278
5900 Sutton Pl, Urbandale, IA 50322 ~5.49 miles northwest of 50381
  • Two star Suburban hotel
  • 3 suites in hotel
From$45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel in Des Moines
+1-888-469-4795
4800 Merle Hay Rd., Des Moines, IA 50322 ~5.51 miles northwest of 50381
  • Midscale Suburban property
  • 24 conference rooms in property
From$89
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites - Des Moines
+1-888-734-9421
4995 Merle Hay Rd., Des Moines, IA 50310 ~5.52 miles northwest of 50381
  • Cheap hotel
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road in Des Moines
+1-888-841-5292
4995 Merle Hay Rd., Des Moines, IA 50322 ~5.54 miles northwest of 50381
  • 3 star property
  • 111 rooms in property
From$62
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Ramada by Wyndham Des Moines Tropics Resort & Conference Center : 5000 Merle Hay Rd.
+1-888-455-5160
5000 Merle Hay Rd., Des Moines, IA 50322 ~5.58 miles northwest of 50381
  • 3 star Suburban property
  • Hotel has 2 floors
From$80
Average 3.0 /5 Review Score Call BookMore Details
Americinn by Wyndham Johnston Des Moines in Johnston
+1-888-965-8297
5050 Merle Hay Rd., Johnston, IA 50131 ~5.82 miles northwest of 50381
  • Two-star Highway property
  • Gym / Fitness Center Available
From$64
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Urbandale / Des Moines : 8711 Plum Dr.
+1-888-906-6358
8711 Plum Dr., Urbandale, IA 50322 ~6.86 miles northwest of 50381
  • Cheap Highway property
  • Hotel has 76 rooms
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Des Moines Urbandale in Urbandale
+1-888-749-6785
8661 Plum Dr., Urbandale, IA 50322 ~6.87 miles northwest of 50381
  • 3 star Suburban property
  • 4 floors in hotel
From$84
Very Good 4.0 /5 Reviews Call BookMore Details
Grandstay Hotel & Suites
+1-888-878-9982
6215 Merle Hay Rd., Johnston, IA 50131 ~6.88 miles northwest of 50381
  • Low Cost Highway property
  • Check in: 3:00pm
From$60
Average 3.0 /5 Review Score Call BookMore Details

Next: Show All Available 50381 Hotels with Pricing

Graph: Upcoming 20 Days of 50381 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Des Moines, IA discounts available. The chart reflects the cheapest Des Moines hotel for each day and each star rating category.

FAQs about hotels near 50381

What are the best rated hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Hilton Des Moines Downtown and Staybridge Suites Des Moines Downtown are the best rated hotels based on customer reviews in the last 365 days.

What are the most up-scale hotels near 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Des Moines Marriott Downtown and Hyatt Place Des Moines are the top 3 luxury hotels near 50381.

What hotels are closest to the area of 50381?

Hotel Fort Des Moines Curio Collection by Hilton, Holiday Inn Express & Suites Des Moines Downtown, and Des Lux Hotel are the properties closest to 50381.

How much does a cheap hotel near 50381 cost per night?

In the last year, a 2 star hotel near 50381 can be as cheap as $103.72 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 50381 cost per night?

In the last year, the average 3 star hotel near 50381 has been $130.00 per night. (based on HotelPlanner prices)

How much does a higher-end hotel near 50381 cost?

In the last year, the average 4 star hotel near 50381 has been $142.70 per night. (based on HotelPlanner prices)

What are the best independent hotels near 50381?

Des Lux Hotel and Surety Hotel are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 50381?

Des Moines Marriott Downtown, Fairfield Inn & Suites by Marriott Des Moines Airport and Fairfield Inn & Suites Des Moines Urbandale are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 50381?

Comfort Inn & Suites Event Center, Quality Inn & Suites Des Moines Airport and Quality Inn & Suites Des Moines - Merle Hay Road are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 50381?

Holiday Inn Express & Suites Des Moines Downtown, Staybridge Suites Des Moines Downtown and Holiday Inn Downtown Mercy Area An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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