Cairo Illinois Accommodations

Find hotels & motels in Cairo using the list below. Search for cheap and discounted hotel and motel rates in or close to Cairo, IL for your upcoming individual or group travel. Discover the best Cairo Illinois hotel/motel rooms. Review the Cairo hotel list below to find the perfect lodging. We also have a map of the Cairo hotels.

Cairo Hotels/Motels & Accommodations

Quality Inn Cairo I-57
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
13201 Kessler Rd., Cairo, IL 62914 +1-888-389-4121
  • Affordable Highway property
  • 2 floors in hotel
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From$60
Poor 2.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Charleston/Sikeston East MO
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
310 South Story, Charleston, MO 63834 +1-888-675-2083 ~10.14 miles southwest of Cairo
  • 2-star Highway property
  • Free comp. breakfast
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From$42
Average 3.5 /5 Latest Reviews Call BookMore Details
Quality Inn Charleston - Sikeston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
102 Drake St., Charleston, MO 63834 +1-800-716-8490 ~11.90 miles southwest of Cairo
  • Low-priced Highway property
  • 9 suites in property
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From$59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
128 Cheekwood Lane, Ullin, IL 62992 +1-800-805-5223 ~17.90 miles north of Cairo
  • Cheap property
  • 2 floors in hotel
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Sikeston Mo : 110 South Interstate Dr.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
110 South Interstate Dr., SIKESTON, MO 63801 +1-888-965-1860 ~21.01 miles west of Cairo
  • Economy property
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Sikeston : 120 South Interstate Dr.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
120 South Interstate Dr., Sikeston, MO 63801 +1-888-788-5576 ~21.04 miles west of Cairo
  • Inexpensive Highway hotel
  • Hotel has 2 floors
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From$43
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston : 220 South Interstate Dr.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
220 South Interstate Dr., Sikeston, MO 63801 +1-888-897-9207 ~21.11 miles west of Cairo
  • Low-priced property
  • Fitness / Gym is on-site
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) - Sikeston
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
100 Matthews Lane, Sikeston, MO 63801 +1-888-311-4278 ~21.35 miles west of Cairo
  • 3 star Highway hotel
  • 40 sleeping rooms in hotel
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From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area : 2609 East Malone
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2609 East Malone, Sikeston, MO 63801 +1-888-469-4795 ~21.37 miles west of Cairo
  • Cheap Convention Center property
  • Complimentary breakfast is offered
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn in Sikeston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
109 Matthews Lane, Sikeston, MO 63801 +1-888-734-9421 ~21.39 miles west of Cairo
  • Midscale Highway property
  • Check in: 11:00
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From$85
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Inn & Suites Sikeston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2608 East Malone Ave., Sikeston, MO 63801 +1-888-841-5292 ~21.42 miles west of Cairo
  • Affordable Highway property
  • Hotel has 14 suites
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From$104
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Sikeston
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2602 East Malone, Sikeston, MO 63801 +1-888-455-5160 ~21.42 miles west of Cairo
  • Three Star Suburban hotel
  • Fitness / Gym is on-site
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Sikeston - Sikeston
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1240 Commerce Dr., Sikeston, MO 63801 +1-888-965-8297 ~24.53 miles west of Cairo
  • Mid-scale Rural hotel
  • 4 floors in hotel
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel - Sikeston
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
115 Hospitality Dr., Sikeston, MO 63801 +1-888-906-6358 ~24.55 miles west of Cairo
  • Mid-scale Rural property
  • Comp. Breakfast
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Residence Inn by Marriott Paducah : 3900 Coleman Crossing Circle
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-749-6785 ~25.70 miles east of Cairo
  • 3-star Suburban property
  • 74 rooms in property
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From$89
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Paducah
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-878-9982 ~25.80 miles east of Cairo
  • Cheap Suburban property
  • Check in time: 3:00 PM
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From$55
Very Good 4.0 /5 Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
100 East Front St., Metropolis, IL 62960 +1-888-389-4485 ~26.30 miles east of Cairo
  • Four-star hotel
  • Hotel has 12 suites
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From$160
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Metropolis : 203 East Front St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
203 East Front St., Metropolis, IL 62960 +1-888-389-4121 ~26.33 miles east of Cairo
  • Low-priced Riverfront property
  • Check-in: 3:00PM
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From$45
Average 3.0 /5 Read Reviews Call BookMore Details
Econo Lodge in Metropolis
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1415 East 5th St., Metropolis, IL 62960 +1-888-675-2083 ~27.39 miles east of Cairo
  • Two-star hotel
  • Check-in time: 11:00
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From$60
Not Good 1.0 /5 Guest Reviews Call BookMore Details
 Econo Lodge Paducah West I-24 in Paducah
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5120 Hinkleville Rd., Paducah, KY 42001 +1-800-716-8490 ~27.58 miles east of Cairo
  • 2-star Airport property
  • Check in time: 15:00pm
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown : 400 Broadway St.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
400 Broadway St., Cape Girardeau, MO 63701 +1-800-805-5223 ~27.66 miles northwest of Cairo
  • 3-star Downtown property
  • Check in: 3:00 pm
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From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Paducah
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
5300 Old Cairo Rd., Paducah, KY 42001 +1-888-965-1860 ~27.67 miles east of Cairo
  • 3 star hotel
  • 3 floors in hotel
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From$40
Poor 2.0 /5 Recent Reviews Call BookMore Details
Drury Suites Paducah
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2930 James Sanders Blvd., Paducah, KY 42001 +1-888-788-5576 ~27.73 miles east of Cairo
  • Three Star Suburban hotel
  • Check in time: 3:00 PM
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From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Quality Suites Paducah I-24 : 2880 James Sanders Blvd.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2880 James Sanders Blvd., Paducah, KY 42001 Website +1-888-897-9207 ~27.76 miles east of Cairo
  • Inexpensive Highway hotel
  • Check-in: 3:00 pm
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Country Inn & Suites by Radisson, Paducah, KY
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
145 Mcbride Lane, Paducah, KY 42001 +1-888-311-4278 ~27.83 miles east of Cairo
  • Midscale Highway property
  • Check in: 3pm
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From$49
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags - Lithia Springs
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
960 West Pointe Court, Lithia Springs, GA 30122 Website +1-888-469-4795 ~27.83 miles east of Cairo
  • 3 star Downtown property
  • Check in: 3:00pm
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From$70
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel 7 Inn in Paducah
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
5001 Hinkleville Rd., Paducah, KY 42001 +1-888-734-9421 ~27.84 miles east of Cairo
  • Two star property
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Paducah : 3960 Coleman Crossing Cir
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3960 Coleman Crossing Cir, Paducah, KY 42001 +1-888-841-5292 ~27.93 miles east of Cairo
  • Midscale Highway hotel
  • Fitness / Gym is on-site
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Candlewood Suites Paducah, an IHG Hotel
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3940 Coleman Crossing Circle, Paducah, KY 42001 +1-888-455-5160 ~27.94 miles east of Cairo
  • 3 star Rural hotel
  • Hotel has a green policy Learn more
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From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Paducah
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3925 Coleman Crossing Cir, Paducah, KY 42001 +1-888-965-8297 ~27.97 miles east of Cairo
  • 3 star Highway property
  • Gym / Fitness Center Available
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From$109
Very Good 4.0 /5 Reviews Call BookMore Details
Comfort Suites
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3918 Coleman Crossing Cir Paducah Ky 42001, Paducah, KY 42001 +1-888-906-6358 ~27.99 miles east of Cairo
  • Inexpensive Rural property
  • Hotel has 72 suites
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn Paducah
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
5135 Cairo Rd., Paducah, KY 42001 +1-888-749-6785 ~28.01 miles east of Cairo
  • Mid-scale hotel
  • Free breakfast available
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From$59
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Paducah
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3950 Coleman Crossing Circle, Paducah, KY 42001 +1-888-878-9982 ~28.03 miles east of Cairo
  • 3-star Rural hotel
  • Hotel has 32 suites
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From$75
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Paducah
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
5106 Old Cairo Rd., Paducah, KY 42001 +1-888-389-4485 ~28.04 miles east of Cairo
  • Low-priced hotel
  • 8 suites in hotel
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From$45
Average 3.5 /5 Review Score Call BookMore Details
American Inn
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
5125 Cairo Rd., Paducah, KY 42001 +1-888-389-4121 ~28.05 miles east of Cairo
  • Two star property
  • Check-in: 14:00
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From$37
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Paducah West, an IHG Hotel
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
3996 Hinkleville Rd., Paducah, KY 42001 +1-888-675-2083 ~28.07 miles east of Cairo
  • 3 star Highway hotel
  • 3 floors in hotel
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From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Auburn Place Hotel & Suites - Paducah : 3994 Hinkleville Rd.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3994 Hinkleville Rd., Paducah, KY 42001 +1-800-716-8490 ~28.08 miles east of Cairo
  • Midscale Airport hotel
  • Check-in: 3:00 PM
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From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Paducah - Paducah
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3835 Technology Dr., Paducah, KY 42001 +1-800-805-5223 ~28.32 miles east of Cairo
  • 3-star Suburban hotel
  • Check-in time: 3:00 pm
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From$89
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Drury Inn Paducah
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3975 Hinkleville Rd., Paducah, KY 42001 +1-888-965-1860 ~28.73 miles east of Cairo
  • Mid-scale Suburban property
  • Gym is available on property
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From$79
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Candlewood Suites Cape Girardeau, an IHG Hotel : 485 South Mount Auburn Rd.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-788-5576 ~28.78 miles northwest of Cairo
  • Low priced Highway hotel
  • Check-in time: 3:00PM
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From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Paducah in Paducah
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
3901 Hinkleville Rd., Paducah, KY 42001 +1-888-897-9207 ~28.78 miles east of Cairo
  • Cheap Highway hotel
  • Free breakfast
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From$50
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Metropolis I-24
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2118 East 5th St., Metropolis, IL 62960 +1-888-311-4278 ~28.90 miles east of Cairo
  • Midscale property
  • Check-in: 11:00
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From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Metropolis in Metropolis
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2055 East 5th St., Metropolis, IL 62960 +1-888-469-4795 ~28.91 miles east of Cairo
  • Low Cost Highway hotel
  • Check-in time: 02:00PM
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Travelers Inn and Suites
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
2550 Lone Oak Rd., Paducah, KY 42003 +1-888-734-9421 ~28.91 miles east of Cairo
  • Low Cost property
  • Check-in time: 2:00PM
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From$38
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Metropolis Il
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
2119 East 5th St., Metropolis, IL 62960 +1-888-841-5292 ~29.06 miles east of Cairo
  • Cheap hotel
  • Check-in time: 11:00 AM
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Metropolis, an IHG Hotel
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
2179 East 5th St., Metropolis, IL 62960 +1-888-455-5160 ~29.12 miles east of Cairo
  • Midscale Rural hotel
  • Hotel has 21 suites
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From$65
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Cape Girardeau I 55 East : 207 South Mount Auburn Rd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-965-8297 ~29.42 miles northwest of Cairo
  • Three Star Highway property
  • 86 sleeping rooms in hotel
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From$80
Excellent 5.0 /5 Latest Reviews Call BookMore Details
Victorian Inn & Suites
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3256 William St., Cape Girardeau, MO 63703 +1-888-906-6358 ~29.43 miles northwest of Cairo
  • Midscale Golf Course property
  • 133 rooms in property
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From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Auburn Place Hotel & Suites - Cape Girardeau
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3265 Williams St., Cape Girardeau, MO 63702 +1-888-749-6785 ~29.44 miles northwest of Cairo
  • Three Star Highway hotel
  • 2 meeting rooms in hotel
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From$58
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3253 William St., Cape Girardeau, MO 63701 +1-888-878-9982 ~29.51 miles northwest of Cairo
  • 3 star property
  • Fitness + Health Center
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From$80
Very Good 4.5 /5 Read Reviews Call BookMore Details

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