Hotels Near Mayo Clinic Florida

Accommodations close to Mayo Clinic are shown in the list below sorted in the order of their distance (closest first). Browse our hotels to find accommodations near Mayo Clinic (Mayo Clinic) for your leisure or corporate trips. Mayo Clinic is located at 4500 San Pablo Rd S. We show the best lodging close to Mayo Clinic so you can review the available Mayo Clinic lodging below and securely book your ideal hotel.

Lodging & Accommodations close by Mayo Clinic

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
+1-888-389-4121
14390 Mayo Blvd., Jacksonville, FL 32224 +1-888-389-4121 ~0.08 miles southwest of Mayo Clinic
~1 minute walk
  • Three Star Beach hotel
  • Gym is available on property
From$50
Very Good 4.0 /5 Recent Reviews Call BookMore Details
The Inn at Mayo Clinic in Jacksonville
+1-888-675-2083
4420 Mary Brigh Dr., Jacksonville, FL 32224 +1-888-675-2083 ~0.24 miles north of Mayo Clinic
~4 minute walk
  • 3-star Beach hotel
  • Hotel has 78 suites
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Residence Inn Jacksonville East in Jacksonville
+1-800-716-8490
4905 San Pablo Rd. South, Jacksonville, FL 32224 +1-800-716-8490 ~0.51 miles south of Mayo Clinic
~9 minute walk
  • Midscale property
From$90
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Enso - Jacksonville
+1-800-805-5223
3650 Enso Wy, Jacksonville, FL 32224 +1-800-805-5223 ~1.24 miles north of Mayo Clinic
~22 minute walk
  • Luxury 5-star Beach property
  • Gym / Fitness Center Available
From$225
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area, an IH : 4791 Windsor Commons Court Jacksonville Fl 3222
+1-888-965-1860
4791 Windsor Commons Court Jacksonville Fl 3222, Jacksonville, FL 32224 +1-888-965-1860 ~1.71 miles west of Mayo Clinic
  • Midscale Golf Course property
  • Check-in: 3:00 PM
From$97
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites & Hampton Inn Beach Blvd. Jacksonville in Jacksonville
+1-888-788-5576
13741 Beach Blvd. Jacksonville Fl 32224, Jacksonville, FL 32224 +1-888-788-5576 ~2.13 miles northwest of Mayo Clinic
  • 3 star property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
+1-888-897-9207
13733 Beach Blvd., Jacksonville, FL 32224 +1-888-897-9207 ~2.13 miles northwest of Mayo Clinic
  • 3-star Suburban property
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
+1-888-311-4278
1220 Marsh Landing Pkwy., Jacksonville Beach, FL 32250 +1-888-311-4278 ~2.43 miles east of Mayo Clinic
  • Midscale Beach property
  • Hotel has 117 rooms
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express Jacksonville Beach, an IHG Hotel in Jacksonville Beach
+1-888-469-4795
1101 Beach Blvd., Jacksonville Beach, FL 32250 +1-888-469-4795 ~2.84 miles northeast of Mayo Clinic
  • Midscale Beach hotel
  • 2 meeting rooms in property
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Four Points by Sheraton Jacksonville Beachfront
+1-888-734-9421
11 1st St. North, Jacksonville Beach, FL 32250 +1-888-734-9421 ~3.40 miles northeast of Mayo Clinic
  • 3-star Beach property
  • 6 floors in property
From$130
Very Good 4.0 /5 Reviews Call BookMore Details
Best Western Oceanfront : 305 1st St. North
+1-888-841-5292
305 1st St. North, Jacksonville Beach, FL 32250 +1-888-841-5292 ~3.49 miles northeast of Mayo Clinic
  • 3-star Beach hotel
  • Comp. Breakfast
From$68
Very Good 4.0 /5 Review Score Call BookMore Details
Casa Marina Hotel in Jacksonville Beach
+1-888-455-5160
691 1st St. North, Jacksonville Beach, FL 32250 +1-888-455-5160 ~3.60 miles northeast of Mayo Clinic
  • 3-star Oceanfront hotel
  • 3 meeting rooms in property
From$110
Average 3.5 /5 Guest Reviews Call BookMore Details
Margaritaville Jacksonville - Jacksonville
+1-888-965-8297
715 1st St. North, Jacksonville, FL 32250 +1-888-965-8297 ~3.63 miles northeast of Mayo Clinic
  • Four star property
  • 172 rooms in property
From$200
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Ponte Vedra Beach Resorts in Ponte Vedra Beach
+1-888-906-6358
200 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 +1-888-906-6358 ~3.78 miles east of Mayo Clinic
  • Luxury Five Star Beach hotel
  • Hotel has 2 floors
From$179
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Jacksonville Beach/Oceanfront
+1-888-749-6785
1515 1st St. North, Jacksonville Beach, FL 32250 +1-888-749-6785 ~3.92 miles northeast of Mayo Clinic
  • Affordable Oceanfront property
  • 3 meeting rooms in property
From$150
Average 3.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Jacksonville Be : 1616 1st St. North
+1-888-878-9982
1616 1st St. North, Jacksonville Beach, FL 32250 +1-888-878-9982 ~3.92 miles northeast of Mayo Clinic
  • Three Star Beach property
  • 2 conference rooms in property
From$129
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Oceanfront Jacksonville Beac : 1617 1st St. North
+1-888-389-4485
1617 1st St. North, Jacksonville Beach, FL 32250 +1-888-389-4485 ~3.93 miles northeast of Mayo Clinic
  • Mid-scale Beach property
  • Check in time: 03:00 PM
From$159
Very Good 4.5 /5 Review Score Call BookMore Details
Red Roof Inn PLUS+ Neptune Beach - Jacksonville Beach : 1401 Atlantic Blvd.
+1-888-389-4121
1401 Atlantic Blvd., Neptune Beach, FL 32266 +1-888-389-4121 ~4.50 miles north of Mayo Clinic
  • 3-star Beach hotel
  • Check-in: 03:00 PM
From$53
Very Good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Jacksonville Town Center
+1-888-675-2083
10573 Brightman Blvd., Jacksonville, FL 32246 +1-888-675-2083 ~4.96 miles west of Mayo Clinic
  • Midscale Downtown property
  • Check-in time: 3:00 PM
From$89
Very Good 4.0 /5 Guest Reviews Call BookMore Details
The Lodge and Club at Ponte Vedra Beach in Ponte Vedra Beach
+1-800-716-8490
607 Ponte Vedra Blvd., Ponte Vedra Beach, FL 32082 +1-800-716-8490 ~4.96 miles southeast of Mayo Clinic
  • Luxury 5 star hotel
  • 66 rooms in hotel
From$250
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
One Ocean Resort and Spa : 1 Ocean Blvd.
+1-800-805-5223
1 Ocean Blvd., Atlantic Beach, FL 32233 +1-800-805-5223 ~5.01 miles northeast of Mayo Clinic
  • Four-star Beach hotel
  • Hotel has 3 suites
From$131
Very Good 4.0 /5 Reviews Call BookMore Details
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
+1-888-965-1860
45 Tournament Players Club Blvd., Ponte Vedra Beach, FL 32082 +1-888-965-1860 ~5.10 miles southeast of Mayo Clinic
  • Midscale Resort property
  • 127 rooms in property
From$129
Very Good 4.5 /5 Reviews Call BookMore Details
Sawgrass Marriott Golf Resort & Spa : 1000 Pga Tour Blvd.
+1-888-788-5576
1000 Pga Tour Blvd., Ponte Vedra Beach, FL 32082 +1-888-788-5576 ~5.15 miles southeast of Mayo Clinic
  • High end Beach property
  • Check-in time: 04:00 pm
From$129
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Jacksonville E 295 Baymeadows An Ihg Hotel in Jacksonville
+1-888-897-9207
11083 Nursery Fields Dr., Jacksonville, FL 32256 +1-888-897-9207 ~5.34 miles southwest of Mayo Clinic
  • 3-star Suburban property
  • Check-in: 3:00pm
From$109
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Jacksonville-South/St. Johns Ctr. : 10434 Midtown Pkwy.
+1-888-311-4278
10434 Midtown Pkwy., Jacksonville, FL 32246 +1-888-311-4278 ~5.41 miles west of Mayo Clinic
  • Affordable Suburban property
  • Check in time: 4:00 pm
From$129
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
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