63781 Hotels/Accommodations

Super 8 by Wyndham Perryville
+1-888-389-4121
1119 Vincent Dr., Perryville, MO 63775 +1-888-389-4121 ~11.21 miles north of 63781
  • Low Cost Highway hotel
  • Access to gym on-site
From$59
Very good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Perryville : 1500 Liberty St.
+1-888-675-2083
1500 Liberty St., Perryville, MO 63775 +1-888-675-2083 ~11.29 miles north of 63781
  • Economy Highway property
  • Check in: 3:00 PM
From$60
Average 3.5 /5 Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri
+1-800-716-8490
225 Drury Lane, Jackson, MO 63755 +1-800-716-8490 ~17.67 miles east of 63781
  • 3 star Suburban hotel
  • Hotel has 4 floors
From$79
Very good 4.5 /5 Read Reviews Call BookMore Details
Comfort Suites
+1-800-805-5223
2904 Old Orchard Rd., Jackson, 63755 United States +1-800-805-5223 ~21.96 miles southeast of 63781
  • Four star Highway property
  • Hotel has 3 floors
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau : 2904 Old Orchard Rd.
+1-888-965-1860
2904 Old Orchard Rd., Jackson, MO 63755 +1-888-965-1860 ~21.96 miles southeast of 63781
  • Mid-scale Highway hotel
  • Check-in time: 3.00 pm
From$65
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau : 3003 South Old Orchard Rd.
+1-888-788-5576
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-788-5576 ~21.97 miles southeast of 63781
  • Midscale Highway hotel
  • 4 floors in property
From$85
Very good 4.0 /5 Read Reviews Call BookMore Details
TRU by Hilton Cape Girardeau
+1-888-897-9207
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 +1-888-897-9207 ~22.71 miles southeast of 63781
  • Affordable Highway property
  • Check in: 3:00 pm
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Arrowrock Inn in Ste Genevieve
+1-888-311-4278
17030 New Bremen Rd., Ste Genevieve, MO 63670 +1-888-311-4278 ~23.40 miles north of 63781
  • 2-star Rural property
  • Free breakfast available
From$49
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn in Cape Girardeau
+1-888-469-4795
2011 North Kingshighway St., Cape Girardeau, MO 63701 +1-888-469-4795 ~23.98 miles southeast of 63781
  • Two star property
  • Free breakfast available
From$60
Very good 4.0 /5 Recent Reviews Call BookMore Details
Drury Lodge in Cape Girardeau
+1-888-734-9421
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-734-9421 ~25.41 miles southeast of 63781
  • 3 star Highway property
  • Comp. Breakfast
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau in Cape Girardeau
+1-888-841-5292
3351 Percy Dr., Cape Girardeau, MO 63701 +1-888-841-5292 ~25.42 miles southeast of 63781
  • 3-star property
  • Fitness center on property
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Suites Cape Girardeau - Cape Girardeau
+1-888-455-5160
3303 Campster Dr., Cape Girardeau, MO 63701 +1-888-455-5160 ~25.51 miles southeast of 63781
  • Midscale Highway property
  • 86 rooms in hotel
From$85
Very good 4.5 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West in Cape Girardeau
+1-888-965-8297
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-965-8297 ~25.60 miles southeast of 63781
  • Two star property
  • Hotel has a green policy Read more
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau in Cape Girardeay
+1-888-906-6358
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-888-906-6358 ~25.65 miles southeast of 63781
  • 3 star property
  • Check-in: 3:00PM
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center in Cape Girardeau
+1-888-749-6785
3248 William St., Cape Girardeau, MO 63701 +1-888-749-6785 ~25.70 miles southeast of 63781
  • Low Cost Highway hotel
  • 3 floors in property
From$66
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55
+1-888-878-9982
3253 William St., Cape Girardeau, MO 63701 +1-888-878-9982 ~25.74 miles southeast of 63781
  • Three Star property
  • 102 suites in hotel
From$80
Very good 4.5 /5 Reviews Call BookMore Details
Auburn Place Hotel & Suites
+1-888-389-4485
3265 Williams St., Cape Girardeau, MO 63702 +1-888-389-4485 ~25.81 miles southeast of 63781
  • Mid-scale Highway hotel
  • 133 sleeping rooms in hotel
From$58
Very good 4.5 /5 Latest Reviews Call BookMore Details
Victorian Inn & Suites in Cape Girardeau
+1-888-389-4121
3256 William St., Cape Girardeau, MO 63703 +1-888-389-4121 ~25.82 miles southeast of 63781
  • Affordable Golf Course property
  • Check-in: 3:00 pm
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East - Cape Girardeau
+1-888-675-2083
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-675-2083 ~25.82 miles southeast of 63781
  • 3 star Highway hotel
  • Comp. Breakfast
From$80
Excellent 5.0 /5 Reviews Call BookMore Details
Candlewood Suites Cape Girardeau by IHG in Cape Girardeau
+1-800-716-8490
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-800-716-8490 ~26.47 miles southeast of 63781
  • 2-star Highway hotel
  • Hotel has 85 suites
From$69
Very good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Chester Il in Chester
+1-800-805-5223
2150 State St., Chester, IL 62233 +1-800-805-5223 ~26.73 miles north of 63781
  • Midscale Rural property
  • Hotel has 2 floors
From$69
Very good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown : 400 Broadway St.
+1-888-965-1860
400 Broadway St., Cape Girardeau, MO 63701 +1-888-965-1860 ~27.81 miles southeast of 63781
  • Midscale Downtown property
  • Check-in time: 3:00 pm
From$80
Very good 4.0 /5 Read Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve - Sainte Genevieve
+1-888-788-5576
21958 Highway 32, Sainte Genevieve, MO 63670 +1-888-788-5576 ~29.84 miles north of 63781
  • Two star Highway hotel
  • Free complimentary breakfast
From$75
Very good 4.0 /5 Reviews Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO in Farmington
+1-888-897-9207
1625 West Columbia St., Farmington, MO 63640 +1-888-897-9207 ~32.21 miles west of 63781
  • 3 star Highway property
  • 94 rooms in hotel
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Farmington
+1-888-311-4278
1400 West Liberty St., Farmington, MO 63640 +1-888-311-4278 ~32.48 miles west of 63781
  • Affordable Rural property
  • Check-in time: 11:00
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Farmington by IHG
+1-888-469-4795
820 Market St., Farmington, MO 63640 +1-888-469-4795 ~32.62 miles northwest of 63781
  • 3 star Rural property
  • Check in time: 3:00pm
From$99
Very good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Farmington
+1-888-734-9421
930 Valley Creek Dr., Farmington, MO 63640 +1-888-734-9421 ~32.72 miles northwest of 63781
  • Low Cost property
  • Check-in: 3:00 pm
From$49
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Farmington
+1-888-841-5292
850 Valley Creek Dr., Farmington, MO 63640 +1-888-841-5292 ~32.79 miles northwest of 63781
  • Midscale Highway hotel
  • Check-in: 3:00pm
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Crown Pointe Lodge, BW Signature Collection - Farmington
+1-888-455-5160
4245 Hunt Rd., Farmington, MO 63640 +1-888-455-5160 ~33.76 miles northwest of 63781
  • 3 star Golf Course hotel
  • Hotel has 17 suites
From$65
Very good 4.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale
+1-888-965-8297
128 East Walnut St., Murphysboro, IL 62966 +1-888-965-8297 ~35.81 miles east of 63781
  • 2-star property
  • 39 rooms in property
Hotel 7 Inn Anna
+1-888-906-6358
100 Richview Dr., Anna, IL 62906 +1-888-906-6358 ~38.81 miles east of 63781
  • Economy hotel
From$60
Very good 4.0 /5 Read Reviews Call BookMore Details
University Inn of Carbondale
+1-888-749-6785
2400 West Main St., Carbondale, IL 62901 +1-888-749-6785 ~39.35 miles east of 63781
  • Affordable property
From$80
Average 3.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale in Carbondale
+1-888-878-9982
200 West Elm St., Carbondale, IL 62901 +1-888-878-9982 ~40.75 miles east of 63781
  • 3-star Downtown hotel
  • Check-in time: 3:00 pm
From$99
Very good 4.0 /5 Reviews Call BookMore Details
Train Inn : 406 East Stoker St.
+1-888-389-4485
406 East Stoker St., Carbondale, IL 62901 +1-888-389-4485 ~41.00 miles east of 63781
  • Affordable Suburban property
  • Check in: 2pm
From$50
Very good 4.0 /5 Review Score Call BookMore Details
Carbondale Value Inn & Suites in Carbondale
+1-888-389-4121
700 East Main St., Carbondale, IL 62901 +1-888-389-4121 ~41.39 miles east of 63781
  • Low Cost Downtown property
  • Check-in time: 3:00pm
From$54
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Carbondale : 1180 East Main St.
+1-888-675-2083
1180 East Main St., Carbondale, IL 62901 +1-888-675-2083 ~42.00 miles east of 63781
  • 2 star hotel
  • 2 suites in hotel
From$58
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Bonne Terre Mo : 1017 Highway K
+1-800-716-8490
1017 Highway K, Bonne Terre, MO 63628 +1-800-716-8490 ~42.04 miles northwest of 63781
  • Two-star property
From$60
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre in Bonne Terre
+1-800-805-5223
8 Northwood Dr., Bonne Terre, MO 63628 +1-800-805-5223 ~42.15 miles northwest of 63781
  • Economical hotel
From$60
Average 3.0 /5 Review Score Call BookMore Details
Best Western Saluki Inn
+1-888-965-1860
801 North Giant City Rd., Carbondale, IL 62902 +1-888-965-1860 ~42.61 miles east of 63781
  • 3 star Downtown property
  • Comp. Breakfast
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Sparta by IHG
+1-888-788-5576
1301 North Market St., Sparta, IL 62286 +1-888-788-5576 ~42.65 miles north of 63781
  • Midscale Rural property
  • 17 suites in property
From$99
Very good 4.0 /5 Review Score Call BookMore Details
Quality Inn Carbondale University Area - Carbondale
+1-888-897-9207
1415 East Main St., Carbondale, IL 62901 +1-888-897-9207 ~42.66 miles east of 63781
  • 3-star Suburban hotel
  • Check-in time: 3:00pm
Hampton Inn Carbondale
+1-888-311-4278
2175 Reed Station Pkwy., Carbondale, IL 62901 +1-888-311-4278 ~43.73 miles east of 63781
  • 3-star Rural property
  • Check-in: 3:00pm
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Carbondale Conference Center An Ihg Hotel : 2300 Reed Station Pkwy.
+1-888-469-4795
2300 Reed Station Pkwy., Carbondale, IL 62901 +1-888-469-4795 ~43.95 miles east of 63781
  • Mid-scale Rural hotel
  • Access to gym on-site
From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Carbondale University Area : 2400 Reed Station Pkwy.
+1-888-734-9421
2400 Reed Station Pkwy., Carbondale, IL 62901 +1-888-734-9421 ~44.09 miles east of 63781
  • Three Star Suburban hotel
  • 24 suites in property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
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