63781 Hotels & Accommodations

Super 8 by Wyndham Perryville - Perryville
+1-888-389-4121
1119 Vincent Dr., Perryville, MO 63775 +1-888-389-4121 ~11.21 miles north of 63781
  • Two star Highway property
  • Comp. Breakfast
From$59
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Perryville - Perryville
+1-888-675-2083
1500 Liberty St., Perryville, MO 63775 +1-888-675-2083 ~11.29 miles north of 63781
  • Two star Highway property
  • Check-in: 3:00 PM
From$60
Average 3.5 /5 Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri : 225 Drury Lane
+1-800-716-8490
225 Drury Lane, Jackson, MO 63755 +1-800-716-8490 ~17.67 miles east of 63781
  • 3-star Suburban hotel
  • 24 suites in property
From$79
Very Good 4.5 /5 Reviews Call BookMore Details
Comfort Suites in Jackson
+1-800-805-5223
2904 Old Orchard Rd., Jackson, 63755 United States +1-800-805-5223 ~21.96 miles southeast of 63781
  • Expensive Highway property
  • Check in: 3:00 PM
From$125
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau
+1-888-965-1860
2904 Old Orchard Rd., Jackson, MO 63755 +1-888-965-1860 ~21.96 miles southeast of 63781
  • Three Star Highway property
  • 3 floors in property
From$65
Average 3.0 /5 Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau : 3003 South Old Orchard Rd.
+1-888-788-5576
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-788-5576 ~21.97 miles southeast of 63781
  • Mid-scale Highway property
  • 4 floors in hotel
From$85
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Arrowrock Inn
+1-888-897-9207
17030 New Bremen Rd., Ste Genevieve, MO 63670 +1-888-897-9207 ~23.40 miles north of 63781
  • Two star Rural hotel
  • Comp. Breakfast
From$49
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn - Cape Girardeau
+1-888-311-4278
2011 North Kingshighway St., Cape Girardeau, MO 63701 +1-888-311-4278 ~23.98 miles southeast of 63781
  • Economical hotel
  • Complimentary breakfast is offered
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau in Cape Girardeau
+1-888-469-4795
3351 Percy Dr., Cape Girardeau, MO 63701 +1-888-469-4795 ~25.40 miles southeast of 63781
  • Mid-scale hotel
  • Access to gym on-site
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Lodge
+1-888-734-9421
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-734-9421 ~25.41 miles southeast of 63781
  • Three Star Highway hotel
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Review Score Call BookMore Details
Drury Suites Cape Girardeau : 3303 Campster Dr.
+1-888-841-5292
3303 Campster Dr., Cape Girardeau, MO 63701 +1-888-841-5292 ~25.51 miles southeast of 63781
  • Mid-scale Highway hotel
  • 5 floors in hotel
From$85
Very Good 4.5 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau West
+1-888-455-5160
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-455-5160 ~25.60 miles southeast of 63781
  • Low priced property
  • Free breakfast available
From$59
Average 3.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau : 433 Cape West Crossing
+1-888-965-8297
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-888-965-8297 ~25.65 miles southeast of 63781
  • Mid-scale property
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center : 3248 William St.
+1-888-906-6358
3248 William St., Cape Girardeau, MO 63701 +1-888-906-6358 ~25.70 miles southeast of 63781
  • Economical Highway hotel
  • 3 floors in property
From$66
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55
+1-888-749-6785
3253 William St., Cape Girardeau, MO 63701 +1-888-749-6785 ~25.74 miles southeast of 63781
  • Mid-scale hotel
  • Check in time: 11:00
From$80
Very Good 4.5 /5 Read Reviews Call BookMore Details
Auburn Place Hotel & Suites in Cape Girardeau
+1-888-878-9982
3265 Williams St., Cape Girardeau, MO 63702 +1-888-878-9982 ~25.81 miles southeast of 63781
  • Mid-scale Highway property
  • Check-in time: 0300 pm
From$58
Very Good 4.5 /5 Review Score Call BookMore Details
Victorian Inn & Suites : 3256 William St.
+1-888-389-4485
3256 William St., Cape Girardeau, MO 63703 +1-888-389-4485 ~25.82 miles southeast of 63781
  • Mid-scale Golf Course property
  • Complimentary breakfast is offered
From$79
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East : 207 South Mount Auburn Rd.
+1-888-389-4121
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-389-4121 ~25.82 miles southeast of 63781
  • Three Star Highway hotel
  • 86 rooms in hotel
From$80
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Candlewood Suites Cape Girardeau, an IHG Hotel
+1-888-675-2083
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-675-2083 ~26.47 miles southeast of 63781
  • Inexpensive Highway hotel
  • 4 floors in hotel
From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Chester Il in Chester
+1-800-716-8490
2150 State St., Chester, IL 62233 +1-800-716-8490 ~26.73 miles north of 63781
  • Affordable Rural property
  • Free breakfast
From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown : 400 Broadway St.
+1-800-805-5223
400 Broadway St., Cape Girardeau, MO 63701 +1-800-805-5223 ~27.81 miles southeast of 63781
  • 3 star Downtown hotel
  • Check in time: 3:00 pm
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve
+1-888-965-1860
21958 Highway 32, Sainte Genevieve, MO 63670 +1-888-965-1860 ~29.84 miles north of 63781
  • 2 star Highway property
  • 6 suites in property
From$75
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO
+1-888-788-5576
1625 West Columbia St., Farmington, MO 63640 +1-888-788-5576 ~32.21 miles west of 63781
  • 3-star Highway hotel
  • Hotel has 3 meeting rooms
From$80
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Farmington - Farmington
+1-888-897-9207
1400 West Liberty St., Farmington, MO 63640 +1-888-897-9207 ~32.48 miles west of 63781
  • Affordable Rural hotel
  • Check in time: 11:00
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Farmington, an IHG Hotel : 820 Market St.
+1-888-311-4278
820 Market St., Farmington, MO 63640 +1-888-311-4278 ~32.62 miles northwest of 63781
  • Affordable Rural hotel
  • 3 floors in hotel
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Farmington
+1-888-469-4795
930 Valley Creek Dr., Farmington, MO 63640 +1-888-469-4795 ~32.72 miles northwest of 63781
  • 2-star property
  • Hotel has 2 floors
From$49
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Farmington - Farmington
+1-888-734-9421
850 Valley Creek Dr., Farmington, MO 63640 +1-888-734-9421 ~32.79 miles northwest of 63781
  • Affordable Highway property
  • Check-in time: 3:00pm
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Crown Pointe Lodge, BW Signature Collection
+1-888-841-5292
4245 Hunt Rd., Farmington, MO 63640 +1-888-841-5292 ~33.76 miles northwest of 63781
  • Affordable Golf Course hotel
  • Check-in: 04:00
From$65
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale in Murphysboro
+1-888-455-5160
128 East Walnut St., Murphysboro, IL 62966 +1-888-455-5160 ~35.81 miles east of 63781
  • Low-priced hotel
  • Hotel has 39 rooms
Hotel 7 Inn Anna
+1-888-965-8297
100 Richview Dr., Anna, IL 62906 +1-888-965-8297 ~38.81 miles east of 63781
  • Two-star property
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
University Inn of Carbondale in Carbondale
+1-888-906-6358
2400 West Main St., Carbondale, IL 62901 +1-888-906-6358 ~39.35 miles east of 63781
  • Three Star hotel
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale in Carbondale
+1-888-749-6785
200 West Elm St., Carbondale, IL 62901 +1-888-749-6785 ~40.75 miles east of 63781
  • Midscale Downtown property
  • 99 rooms in property
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Train Inn
+1-888-878-9982
406 East Stoker St., Carbondale, IL 62901 +1-888-878-9982 ~41.00 miles east of 63781
  • 3-star Suburban hotel
  • 7 sleeping rooms in hotel
From$50
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Carbondale Value Inn & Suites - Carbondale
+1-888-389-4485
700 East Main St., Carbondale, IL 62901 +1-888-389-4485 ~41.39 miles east of 63781
  • Economy Downtown property
  • 41 sleeping rooms in hotel
From$54
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Carbondale in Carbondale
+1-888-389-4121
1180 East Main St., Carbondale, IL 62901 +1-888-389-4121 ~42.00 miles east of 63781
  • 2-star property
  • Free comp. breakfast
From$58
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Bonne Terre Mo : 1017 Highway K
+1-888-675-2083
1017 Highway K, Bonne Terre, MO 63628 +1-888-675-2083 ~42.04 miles northwest of 63781
  • Low priced hotel
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre in Bonne Terre
+1-800-716-8490
8 Northwood Dr., Bonne Terre, MO 63628 +1-800-716-8490 ~42.15 miles northwest of 63781
  • Two star hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
Best Western Saluki Inn
+1-800-805-5223
801 North Giant City Rd., Carbondale, IL 62902 +1-800-805-5223 ~42.61 miles east of 63781
  • 3-star Downtown hotel
  • 3 floors in property
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Sparta, an IHG Hotel
+1-888-965-1860
1301 North Market St., Sparta, IL 62286 +1-888-965-1860 ~42.65 miles north of 63781
  • 3 star Rural property
  • Hotel has 74 rooms
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn Carbondale University Area
+1-888-788-5576
1415 East Main St., Carbondale, IL 62901 +1-888-788-5576 ~42.66 miles east of 63781
  • 3-star Suburban hotel
  • Hotel has 2 floors
Hampton Inn Carbondale
+1-888-897-9207
2175 Reed Station Pkwy., Carbondale, IL 62901 +1-888-897-9207 ~43.73 miles east of 63781
  • 3-star Rural property
  • 2 meeting rooms in property
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Carbondale Conference Center An Ihg Hotel : 2300 Reed Station Pkwy.
+1-888-311-4278
2300 Reed Station Pkwy., Carbondale, IL 62901 +1-888-311-4278 ~43.95 miles east of 63781
  • Three Star Rural property
  • Hotel has 5 floors
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Carbondale University Area
+1-888-469-4795
2400 Reed Station Pkwy., Carbondale, IL 62901 +1-888-469-4795 ~44.09 miles east of 63781
  • Midscale Suburban hotel
  • 24 suites in hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
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