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63781 Hotels, Motels & Accommodations

Super 8 by Wyndham Perryville
+1-888-389-4121
1119 Vincent Dr., Perryville, MO 63775 ~11.21 miles north of 63781
  • Inexpensive Highway property
  • Fitness + Health Center
From$59
Very Good 4.0 /5 Latest Reviews Call BookMore Details
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Days Inn by Wyndham Perryville : 1500 Liberty St.
+1-888-675-2083
1500 Liberty St., Perryville, MO 63775 ~11.29 miles north of 63781
  • Economy Highway property
  • Check in time: 3:00 PM
From$60
Average 3.5 /5 Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri
+1-800-716-8490
225 Drury Lane, Jackson, MO 63755 ~17.67 miles east of 63781
  • Midscale Suburban property
  • 4 conference rooms in property
From$79
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Comfort Suites in Jackson
+1-800-805-5223
2904 Old Orchard Rd., Jackson, 63755 United States ~21.96 miles southeast of 63781
  • Four-star Highway hotel
  • 64 suites in hotel
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau in Jackson
+1-888-965-1860
2904 Old Orchard Rd., Jackson, MO 63755 ~21.96 miles southeast of 63781
  • Three Star Highway hotel
  • Hotel has an eco-friendly policy Learn more
From$65
Average 3.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau - Jackson
+1-888-788-5576
3003 South Old Orchard Rd., Jackson, MO 63755 ~21.97 miles southeast of 63781
  • Midscale Highway property
  • Free complimentary breakfast
From$85
Very Good 4.0 /5 Read Reviews Call BookMore Details
TRU by Hilton Cape Girardeau
+1-888-897-9207
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 ~22.71 miles southeast of 63781
  • Affordable Riverfront property
  • Check-in: 3:00 pm
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Arrowrock Inn
+1-888-311-4278
17030 New Bremen Rd., Ste Genevieve, MO 63670 ~23.40 miles north of 63781
  • Low-priced Rural property
  • Hotel has 32 rooms
From$49
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn - Cape Girardeau
+1-888-469-4795
2011 North Kingshighway St., Cape Girardeau, MO 63701 ~23.98 miles southeast of 63781
  • Inexpensive hotel
  • 49 rooms in property
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Drury Lodge
+1-888-734-9421
104 South Vantage Dr., Cape Girardeau, MO 63701 ~25.41 miles southeast of 63781
  • 3-star Highway property
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-841-5292
3351 Percy Dr., Cape Girardeau, MO 63701 ~25.42 miles southeast of 63781
  • Affordable property
  • Check-in time: 3pm
From$59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Suites Cape Girardeau
+1-888-455-5160
3303 Campster Dr., Cape Girardeau, MO 63701 ~25.51 miles southeast of 63781
  • 3 star Highway property
  • 79 suites in property
From$85
Very Good 4.5 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau West - Cape Girardeau
+1-888-965-8297
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~25.60 miles southeast of 63781
  • Low-priced property
  • Hotel has 3 floors
From$59
Average 3.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Cape Girardeau
+1-888-906-6358
433 Cape West Crossing, Cape Girardeay, MO 63703 ~25.65 miles southeast of 63781
  • 3 star hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center in Cape Girardeau
+1-888-749-6785
3248 William St., Cape Girardeau, MO 63701 ~25.70 miles southeast of 63781
  • Two star Highway property
  • Free breakfast available
From$66
Very Good 4.0 /5 Guest Reviews Call BookMore Details
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Holiday Inn Express & Suites Cape Girardeau I 55 - Cape Girardeau
+1-888-878-9982
3253 William St., Cape Girardeau, MO 63701 ~25.74 miles southeast of 63781
  • Affordable property
  • Fitness + Health Center
From$80
Very Good 4.5 /5 Review Score Call BookMore Details
Auburn Place Hotel & Suites in Cape Girardeau
+1-888-389-4485
3265 Williams St., Cape Girardeau, MO 63702 ~25.81 miles southeast of 63781
  • Three Star Highway property
  • 2 floors in property
From$58
Very Good 4.5 /5 Reviews Call BookMore Details
Victorian Inn & Suites - Cape Girardeau
+1-888-389-4121
3256 William St., Cape Girardeau, MO 63703 ~25.82 miles southeast of 63781
  • Mid-scale Golf Course property
  • Comp. Breakfast
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East - Cape Girardeau
+1-888-675-2083
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~25.82 miles southeast of 63781
  • 3-star Highway property
  • Hotel has 86 rooms
From$80
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
Candlewood Suites Cape Girardeau, an IHG Hotel
+1-800-716-8490
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~26.47 miles southeast of 63781
  • 2 star Highway hotel
  • Check in: 3:00PM
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Chester Il - Chester
+1-800-805-5223
2150 State St., Chester, IL 62233 ~26.73 miles north of 63781
  • Mid-scale Rural hotel
  • Free breakfast available
From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown
+1-888-965-1860
400 Broadway St., Cape Girardeau, MO 63701 ~27.81 miles southeast of 63781
  • Three Star Downtown hotel
  • 13 suites in hotel
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve - Sainte Genevieve
+1-888-788-5576
21958 Highway 32, Sainte Genevieve, MO 63670 ~29.84 miles north of 63781
  • Two star Highway hotel
  • Check in time: 3:00 pm
From$75
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO : 1625 West Columbia St.
+1-888-897-9207
1625 West Columbia St., Farmington, MO 63640 ~32.21 miles west of 63781
  • 3-star Highway hotel
  • 2 floors in hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn Farmington in Farmington
+1-888-311-4278
1400 West Liberty St., Farmington, MO 63640 ~32.48 miles west of 63781
  • Affordable Rural hotel
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Farmington, an IHG Hotel - Farmington
+1-888-469-4795
820 Market St., Farmington, MO 63640 ~32.62 miles northwest of 63781
  • Mid-scale Rural property
  • Hotel has 20 suites
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Farmington - Farmington
+1-888-734-9421
930 Valley Creek Dr., Farmington, MO 63640 ~32.72 miles northwest of 63781
  • 2 star property
  • 60 sleeping rooms in hotel
From$49
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Farmington - Farmington
+1-888-841-5292
850 Valley Creek Dr., Farmington, MO 63640 ~32.79 miles northwest of 63781
  • Three Star Highway property
  • Check-in: 3:00pm
From$80
Average 3.0 /5 Reviews Call BookMore Details
Crown Pointe Lodge, BW Signature Collection in Farmington
+1-888-455-5160
4245 Hunt Rd., Farmington, MO 63640 ~33.76 miles northwest of 63781
  • 3 star Golf Course property
  • Complimentary breakfast is offered
From$64
Very Good 4.0 /5 Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale : 128 East Walnut St.
+1-888-965-8297
128 East Walnut St., Murphysboro, IL 62966 ~35.81 miles east of 63781
  • 2-star property
  • 39 rooms in hotel
From$48
Poor 2.5 /5 Reviews Call BookMore Details
Hotel 7 Inn Anna
+1-888-906-6358
100 Richview Dr., Anna, IL 62906 ~38.81 miles east of 63781
  • Two star hotel
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
University Inn of Carbondale in Carbondale
+1-888-749-6785
2400 West Main St., Carbondale, IL 62901 ~39.35 miles east of 63781
  • Mid-scale hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale
+1-888-878-9982
200 West Elm St., Carbondale, IL 62901 ~40.75 miles east of 63781
  • Three Star Downtown property
  • 99 rooms in hotel
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Train Inn : 406 East Stoker St.
+1-888-389-4485
406 East Stoker St., Carbondale, IL 62901 ~41.00 miles east of 63781
  • Three Star Suburban hotel
  • Free breakfast available
From$50
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Carbondale Value Inn & Suites in Carbondale
+1-888-389-4121
700 East Main St., Carbondale, IL 62901 ~41.39 miles east of 63781
  • Low-priced Downtown hotel
  • 41 sleeping rooms in hotel
From$54
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Carbondale
+1-888-675-2083
1180 East Main St., Carbondale, IL 62901 ~42.00 miles east of 63781
  • Low Cost property
  • 63 sleeping rooms in hotel
From$58
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Bonne Terre Mo in Bonne Terre
+1-800-716-8490
1017 Highway K, Bonne Terre, MO 63628 ~42.04 miles northwest of 63781
  • Low priced property
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre
+1-800-805-5223
8 Northwood Dr., Bonne Terre, MO 63628 ~42.15 miles northwest of 63781
  • Low-priced property
  • Check in time: 11:00 AM
From$60
Average 3.0 /5 Reviews Call BookMore Details
Best Western Saluki Inn : 801 North Giant City Rd.
+1-888-965-1860
801 North Giant City Rd., Carbondale, IL 62902 ~42.61 miles east of 63781
  • 3 star Downtown property
  • 3 floors in property
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Sparta, an IHG Hotel
+1-888-788-5576
1301 North Market St., Sparta, IL 62286 ~42.65 miles north of 63781
  • Three Star Rural property
  • Gym is available on property
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn Carbondale University Area - Carbondale
+1-888-897-9207
1415 East Main St., Carbondale, IL 62901 ~42.66 miles east of 63781
  • Affordable Suburban hotel
  • Hotel has 2 suites
From$30
Poor 2.0 /5 Reviews Call BookMore Details
Hampton Inn Carbondale - Carbondale
+1-888-311-4278
2175 Reed Station Pkwy., Carbondale, IL 62901 ~43.73 miles east of 63781
  • 3 star Rural hotel
  • 2 meeting rooms in hotel
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Carbondale Conference Center An Ihg Hotel - Carbondale
+1-888-469-4795
2300 Reed Station Pkwy., Carbondale, IL 62901 ~43.95 miles east of 63781
  • Mid-scale Rural hotel
  • Check in: 3:00 pm
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Carbondale University Area in Carbondale
+1-888-734-9421
2400 Reed Station Pkwy., Carbondale, IL 62901 ~44.09 miles east of 63781
  • Affordable Suburban property
  • Hotel has 24 suites
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: Show All Available 63781 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 63781 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Perryville, MO discounts available. The chart reflects the cheapest Perryville hotel for each day and each star rating category.

FAQs about hotels near 63781

What are the most favored hotels near 63781?

Hampton Inn Cape Girardeau I 55 East, Drury Inn & Suites Jackson Missouri and Drury Suites Cape Girardeau are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels near 63781?

Comfort Suites, Drury Inn & Suites Jackson Missouri and Comfort Suites Jackson-Cape Girardeau are the top 3 luxury hotels near 63781.

What hotels are closest to the area of 63781?

Super 8 by Wyndham Perryville, Days Inn by Wyndham Perryville, and Drury Inn & Suites Jackson Missouri are the properties closest to 63781.

How much does a cheap hotel near 63781 cost per night?

In the last year, a 2 star hotel near 63781 can be as cheap as $69.73 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 63781 cost per night?

In the last year, the average 3 star hotel near 63781 has been $97.25 per night. (based on HotelPlanner prices)

What are the best independent hotels near 63781?

Drury Suites Cape Girardeau, Auburn Place Hotel & Suites and Arrowrock Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 63781?

Courtyard by Marriott Cape Girardeau Downtown and Fairfield Inn & Suites Cape Girardeau are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 63781?

Quality Inn, Comfort Suites Jackson-Cape Girardeau and Quality Inn Farmington are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels near 63781?

Crown Pointe Lodge, BW Signature Collection and Best Western Saluki Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 63781?

Holiday Inn Express & Suites Cape Girardeau I 55, Candlewood Suites Cape Girardeau, an IHG Hotel and Holiday Inn Express & Suites Farmington, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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