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63781 Hotels, Motels & Accommodations

Super 8 by Wyndham Perryville in Perryville
+1-888-389-4121
1119 Vincent Dr., Perryville, MO 63775 ~11.21 miles north of 63781
  • Cheap Highway hotel
  • Comp. Breakfast
From$59
Very good 4.0 /5 Recent Reviews Call BookMore Details
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Days Inn by Wyndham Perryville - Perryville
+1-888-675-2083
1500 Liberty St., Perryville, MO 63775 ~11.29 miles north of 63781
  • Low priced Highway hotel
  • Check in time: 3:00 PM
From$60
Average 3.5 /5 Guest Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri : 225 Drury Lane
+1-800-716-8490
225 Drury Lane, Jackson, MO 63755 ~17.67 miles east of 63781
  • Affordable Suburban hotel
  • Has environment-friendly policy See policy
From$79
Very good 4.5 /5 Reviews Call BookMore Details
Comfort Suites
+1-800-805-5223
2904 Old Orchard Rd., Jackson, 63755 United States ~21.96 miles southeast of 63781
  • High end Highway property
  • Access to gym on-site
From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau
+1-888-965-1860
2904 Old Orchard Rd., Jackson, MO 63755 ~21.96 miles southeast of 63781
  • Mid-scale Highway property
  • 64 rooms in property
From$65
Average 3.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau
+1-888-788-5576
3003 South Old Orchard Rd., Jackson, MO 63755 ~21.97 miles southeast of 63781
  • Three Star Highway hotel
  • Free complimentary breakfast
From$85
Very good 4.0 /5 Read Reviews Call BookMore Details
TRU by Hilton Cape Girardeau
+1-888-897-9207
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 ~22.71 miles southeast of 63781
  • Mid-scale Highway hotel
  • Check in: 3:00 pm
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Arrowrock Inn
+1-888-311-4278
17030 New Bremen Rd., Ste Genevieve, MO 63670 ~23.40 miles north of 63781
  • Two-star Rural property
  • 32 rooms in hotel
From$49
Very good 4.0 /5 Reviews Call BookMore Details
Quality Inn : 2011 North Kingshighway St.
+1-888-469-4795
2011 North Kingshighway St., Cape Girardeau, MO 63701 ~23.98 miles southeast of 63781
  • Cheap property
  • Free breakfast available
From$60
Very good 4.0 /5 Guest Reviews Call BookMore Details
Drury Lodge - Cape Girardeau
+1-888-734-9421
104 South Vantage Dr., Cape Girardeau, MO 63701 ~25.41 miles southeast of 63781
  • Affordable Highway hotel
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Review Score Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau : 3351 Percy Dr.
+1-888-841-5292
3351 Percy Dr., Cape Girardeau, MO 63701 ~25.42 miles southeast of 63781
  • Mid-scale hotel
  • Check in time: 3pm
From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Drury Suites Cape Girardeau
+1-888-455-5160
3303 Campster Dr., Cape Girardeau, MO 63701 ~25.51 miles southeast of 63781
  • Affordable Highway property
  • Access to gym on-site
From$85
Very good 4.5 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau West - Cape Girardeau
+1-888-965-8297
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~25.60 miles southeast of 63781
  • Economy hotel
  • Hotel has an eco-friendly policy See policy
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau - Cape Girardeay
+1-888-906-6358
433 Cape West Crossing, Cape Girardeay, MO 63703 ~25.65 miles southeast of 63781
  • Affordable property
  • Check-in: 3:00PM
From$80
Average 3.0 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center in Cape Girardeau
+1-888-749-6785
3248 William St., Cape Girardeau, MO 63701 ~25.70 miles southeast of 63781
  • Cheap Highway property
  • Free breakfast
From$66
Very good 4.0 /5 Read Reviews Call BookMore Details
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Holiday Inn Express & Suites Cape Girardeau I 55 in Cape Girardeau
+1-888-878-9982
3253 William St., Cape Girardeau, MO 63701 ~25.74 miles southeast of 63781
  • Mid-scale hotel
  • Hotel has 102 suites
From$80
Very good 4.5 /5 Review Score Call BookMore Details
Auburn Place Hotel & Suites in Cape Girardeau
+1-888-389-4485
3265 Williams St., Cape Girardeau, MO 63702 ~25.81 miles southeast of 63781
  • Three Star Highway hotel
  • Fitness + Health Center
From$58
Very good 4.5 /5 Reviews Call BookMore Details
Victorian Inn & Suites - Cape Girardeau
+1-888-389-4121
3256 William St., Cape Girardeau, MO 63703 ~25.82 miles southeast of 63781
  • Mid-scale Golf Course hotel
  • 2 meeting rooms in property
From$79
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East
+1-888-675-2083
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~25.82 miles southeast of 63781
  • Midscale Highway hotel
  • 4 floors in hotel
From$80
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Candlewood Suites Cape Girardeau by IHG
+1-800-716-8490
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~26.47 miles southeast of 63781
  • 2-star Highway hotel
  • Hotel has a green policy See policy
From$69
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Chester Il - Chester
+1-800-805-5223
2150 State St., Chester, IL 62233 ~26.73 miles north of 63781
  • Three Star Rural property
  • Free breakfast available
From$69
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown - Cape Girardeau
+1-888-965-1860
400 Broadway St., Cape Girardeau, MO 63701 ~27.81 miles southeast of 63781
  • Mid-scale Downtown hotel
  • Check-in time: 3:00 pm
From$80
Very good 4.0 /5 Latest Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve : 21958 Highway 32
+1-888-788-5576
21958 Highway 32, Sainte Genevieve, MO 63670 ~29.84 miles north of 63781
  • Two-star Highway property
  • Hotel has 2 floors
From$75
Very good 4.0 /5 Review Score Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO in Farmington
+1-888-897-9207
1625 West Columbia St., Farmington, MO 63640 ~32.21 miles west of 63781
  • Midscale Highway hotel
  • Free complimentary breakfast
From$80
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Farmington : 1400 West Liberty St.
+1-888-311-4278
1400 West Liberty St., Farmington, MO 63640 ~32.48 miles west of 63781
  • Affordable Rural hotel
  • 48 rooms in hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Farmington by IHG in Farmington
+1-888-469-4795
820 Market St., Farmington, MO 63640 ~32.62 miles northwest of 63781
  • 3 star Rural property
  • Hotel has 20 suites
From$99
Very good 4.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Farmington
+1-888-734-9421
930 Valley Creek Dr., Farmington, MO 63640 ~32.72 miles northwest of 63781
  • Two-star hotel
  • 60 sleeping rooms in hotel
From$49
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Farmington
+1-888-841-5292
850 Valley Creek Dr., Farmington, MO 63640 ~32.79 miles northwest of 63781
  • Midscale Highway property
  • Hotel has 3 floors
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Crown Pointe Lodge, BW Signature Collection
+1-888-455-5160
4245 Hunt Rd., Farmington, MO 63640 ~33.76 miles northwest of 63781
  • 3-star Golf Course hotel
  • Hotel has 17 suites
From$65
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale - Murphysboro
+1-888-965-8297
128 East Walnut St., Murphysboro, IL 62966 ~35.81 miles east of 63781
  • Low priced hotel
  • Hotel has 39 rooms
Hotel 7 Inn Anna in Anna
+1-888-906-6358
100 Richview Dr., Anna, IL 62906 ~38.81 miles east of 63781
  • Inexpensive property
From$60
Very good 4.0 /5 Reviews Call BookMore Details
University Inn of Carbondale
+1-888-749-6785
2400 West Main St., Carbondale, IL 62901 ~39.35 miles east of 63781
  • Mid-scale hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale in Carbondale
+1-888-878-9982
200 West Elm St., Carbondale, IL 62901 ~40.75 miles east of 63781
  • 3 star Downtown hotel
  • Check in: 3:00 pm
From$99
Very good 4.0 /5 Latest Reviews Call BookMore Details
Train Inn - Carbondale
+1-888-389-4485
406 East Stoker St., Carbondale, IL 62901 ~41.00 miles east of 63781
  • 3 star Suburban hotel
  • 2 floors in property
From$50
Very good 4.0 /5 Read Reviews Call BookMore Details
Carbondale Value Inn & Suites
+1-888-389-4121
700 East Main St., Carbondale, IL 62901 ~41.39 miles east of 63781
  • Two-star Downtown hotel
  • Hotel has 2 floors
From$54
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Carbondale in Carbondale
+1-888-675-2083
1180 East Main St., Carbondale, IL 62901 ~42.00 miles east of 63781
  • Economy hotel
  • 2 suites in hotel
From$58
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Bonne Terre Mo
+1-800-716-8490
1017 Highway K, Bonne Terre, MO 63628 ~42.04 miles northwest of 63781
  • 2 star hotel
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre
+1-800-805-5223
8 Northwood Dr., Bonne Terre, MO 63628 ~42.15 miles northwest of 63781
  • 2 star property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Best Western Saluki Inn : 801 North Giant City Rd.
+1-888-965-1860
801 North Giant City Rd., Carbondale, IL 62902 ~42.61 miles east of 63781
  • 3 star Downtown hotel
  • 3 floors in hotel
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Sparta by IHG : 1301 North Market St.
+1-888-788-5576
1301 North Market St., Sparta, IL 62286 ~42.65 miles north of 63781
  • Midscale Rural hotel
  • 74 sleeping rooms in hotel
From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn Carbondale University Area in Carbondale
+1-888-897-9207
1415 East Main St., Carbondale, IL 62901 ~42.66 miles east of 63781
  • 3-star Suburban property
  • Free comp. breakfast
Hampton Inn Carbondale : 2175 Reed Station Pkwy.
+1-888-311-4278
2175 Reed Station Pkwy., Carbondale, IL 62901 ~43.73 miles east of 63781
  • Affordable Rural hotel
  • 2 conference rooms in property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Carbondale Conference Center An Ihg Hotel
+1-888-469-4795
2300 Reed Station Pkwy., Carbondale, IL 62901 ~43.95 miles east of 63781
  • 3 star Rural hotel
  • Check-in: 3:00 pm
From$99
Very good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites Carbondale University Area in Carbondale
+1-888-734-9421
2400 Reed Station Pkwy., Carbondale, IL 62901 Website ~44.09 miles east of 63781
  • 3 star Suburban property
  • Free breakfast
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available 63781 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 63781 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Perryville, MO discounts available. The chart reflects the cheapest Perryville hotel for each day and each star rating category.

FAQs about hotels near 63781

What are the most favored hotels near 63781?

Hampton Inn Cape Girardeau I 55 East, Drury Inn & Suites Jackson Missouri and Drury Suites Cape Girardeau are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels near 63781?

Comfort Suites, Drury Inn & Suites Jackson Missouri and Comfort Suites Jackson-Cape Girardeau are the top 3 luxury hotels near 63781.

What hotels are closest to the area of 63781?

Super 8 by Wyndham Perryville, Days Inn by Wyndham Perryville, and Drury Inn & Suites Jackson Missouri are the properties closest to 63781.

How much does a cheap hotel near 63781 cost per night?

In the last year, a 2 star hotel near 63781 can be as cheap as $69.73 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 63781 cost per night?

In the last year, the average 3 star hotel near 63781 has been $97.96 per night. (based on HotelPlanner prices)

What are the best independent hotels near 63781?

Drury Suites Cape Girardeau, Auburn Place Hotel & Suites and Arrowrock Inn are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 63781?

Courtyard by Marriott Cape Girardeau Downtown and Fairfield Inn & Suites Cape Girardeau are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 63781?

Quality Inn, Comfort Suites Jackson-Cape Girardeau and Quality Inn Farmington are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels near 63781?

Crown Pointe Lodge, BW Signature Collection and Best Western Saluki Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 63781?

Holiday Inn Express & Suites Cape Girardeau I 55, Candlewood Suites Cape Girardeau by IHG and Holiday Inn Express & Suites Farmington by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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