63780 Hotels/Motels & Accommodations

Candlewood Suites Cape Girardeau, an IHG Hotel in Cape Girardeau
+1-888-389-4121
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-389-4121 ~9.95 miles northwest of 63780
  • Low priced Highway hotel
  • Check in time: 3:00PM
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown
+1-888-675-2083
400 Broadway St., Cape Girardeau, MO 63701 +1-888-675-2083 ~10.05 miles north of 63780
  • Midscale Downtown hotel
  • Hotel has 5 floors
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East in Cape Girardeau
+1-800-716-8490
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-800-716-8490 ~10.67 miles northwest of 63780
  • Three Star Highway hotel
  • Check-in: 15:00
From$80
Excellent 5.0 /5 Reviews Call BookMore Details
Victorian Inn & Suites
+1-800-805-5223
3256 William St., Cape Girardeau, MO 63703 +1-800-805-5223 ~10.74 miles northwest of 63780
  • Affordable Golf Course property
  • 2 conference rooms in property
From$79
Average 3.0 /5 Latest Reviews Call BookMore Details
Auburn Place Hotel & Suites
+1-888-965-1860
3265 Williams St., Cape Girardeau, MO 63702 +1-888-965-1860 ~10.74 miles northwest of 63780
  • Three Star Highway property
  • Access to gym on-site
From$58
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 in Cape Girardeau
+1-888-788-5576
3253 William St., Cape Girardeau, MO 63701 +1-888-788-5576 ~10.77 miles northwest of 63780
  • Three Star hotel
  • Hotel has 102 rooms
From$80
Very Good 4.5 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau
+1-888-897-9207
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-888-897-9207 ~10.80 miles northwest of 63780
  • Midscale hotel
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center - Cape Girardeau
+1-888-311-4278
3248 William St., Cape Girardeau, MO 63701 +1-888-311-4278 ~10.83 miles northwest of 63780
  • Low-priced Highway hotel
  • Hotel has 3 floors
From$66
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West in Cape Girardeau
+1-888-469-4795
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-469-4795 ~10.84 miles northwest of 63780
  • Economy hotel
  • Check in: 3:00 PM
From$59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Suites Cape Girardeau : 3303 Campster Dr.
+1-888-734-9421
3303 Campster Dr., Cape Girardeau, MO 63701 +1-888-734-9421 ~10.95 miles northwest of 63780
  • Three Star Highway hotel
  • Check-in time: 3:00 PM
From$85
Very Good 4.5 /5 Review Score Call BookMore Details
Drury Lodge
+1-888-841-5292
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-888-841-5292 ~11.11 miles northwest of 63780
  • 3-star Highway hotel
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-455-5160
3351 Percy Dr., Cape Girardeau, MO 63701 +1-888-455-5160 ~11.13 miles northwest of 63780
  • Three Star hotel
  • Free comp. breakfast
From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn
+1-888-965-8297
2011 North Kingshighway St., Cape Girardeau, MO 63701 +1-888-965-8297 ~13.06 miles northwest of 63780
  • Low Cost hotel
  • Free breakfast
From$60
Very Good 4.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau : 3003 South Old Orchard Rd.
+1-888-906-6358
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-906-6358 ~14.80 miles northwest of 63780
  • Midscale Highway property
  • Fitness center on property
From$85
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau
+1-888-749-6785
2904 Old Orchard Rd., Jackson, MO 63755 +1-888-749-6785 ~14.91 miles northwest of 63780
  • Three Star Highway property
  • 64 suites in property
From$65
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Suites
+1-888-878-9982
2904 Old Orchard Rd., Jackson, 63755 United States +1-888-878-9982 ~14.91 miles northwest of 63780
  • Four star Highway hotel
  • 64 suites in property
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Cairo I-57 in Cairo
+1-888-389-4485
13201 Kessler Rd., Cairo, IL 62914 +1-888-389-4485 ~17.88 miles east of 63780
  • Mid-scale Highway property
  • 38 rooms in hotel
Super 8 by Wyndham Charleston/Sikeston East MO in Charleston
+1-888-389-4121
310 South Story, Charleston, MO 63834 +1-888-389-4121 ~19.03 miles southeast of 63780
  • Inexpensive Highway property
  • 7 suites in hotel
From$42
Average 3.5 /5 Latest Reviews Call BookMore Details
Motel 6 Sikeston Mo : 110 South Interstate Dr.
+1-888-675-2083
110 South Interstate Dr., SIKESTON, MO 63801 +1-888-675-2083 ~19.03 miles south of 63780
  • Low priced property
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western Plus Sikeston in Sikeston
+1-800-716-8490
120 South Interstate Dr., Sikeston, MO 63801 +1-800-716-8490 ~19.07 miles south of 63780
  • Two-star Highway property
  • Has environment-friendly policy See more
From$43
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn Charleston - Sikeston in Charleston
+1-800-805-5223
102 Drake St., Charleston, MO 63834 +1-800-805-5223 ~19.09 miles south of 63780
  • Cheap Highway hotel
  • Fitness / Gym is on-site
From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds : 128 Cheekwood Lane
+1-888-965-1860
128 Cheekwood Lane, Ullin, IL 62992 +1-888-965-1860 ~19.15 miles east of 63780
  • Cheap hotel
  • Free breakfast available
From$60
Average 3.0 /5 Reviews Call BookMore Details
Drury Inn & Suites Sikeston in Sikeston
+1-888-788-5576
2608 East Malone Ave., Sikeston, MO 63801 +1-888-788-5576 ~19.16 miles south of 63780
  • 3-star Highway hotel
  • Free breakfast available
From$104
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Sikeston - Sikeston
+1-888-897-9207
2602 East Malone, Sikeston, MO 63801 +1-888-897-9207 ~19.16 miles south of 63780
  • Three Star Suburban property
  • 80 rooms in hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) : 100 Matthews Lane
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 +1-888-311-4278 ~19.20 miles south of 63780
  • Midscale Highway hotel
  • Check in: 3:00 PM
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn : 109 Matthews Lane
+1-888-469-4795
109 Matthews Lane, Sikeston, MO 63801 +1-888-469-4795 ~19.21 miles south of 63780
  • Three Star Highway hotel
  • Hotel has 64 rooms
From$85
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston - Sikeston
+1-888-734-9421
220 South Interstate Dr., Sikeston, MO 63801 +1-888-734-9421 ~19.24 miles south of 63780
  • 2-star property
  • Check in: 03:00 PM
From$60
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Sikeston/Miner Area in Sikeston
+1-888-841-5292
2609 East Malone, Sikeston, MO 63801 +1-888-841-5292 ~19.30 miles south of 63780
  • Two star Convention Center hotel
  • Comp. Breakfast
From$60
Average 3.0 /5 Review Score Call BookMore Details
Drury Inn & Suites Jackson Missouri
+1-888-455-5160
225 Drury Lane, Jackson, MO 63755 +1-888-455-5160 ~20.25 miles northwest of 63780
  • Three Star Suburban property
  • Free breakfast available
From$79
Very Good 4.5 /5 Review Score Call BookMore Details
Hampton Inn Sikeston : 1240 Commerce Dr.
+1-888-965-8297
1240 Commerce Dr., Sikeston, MO 63801 +1-888-965-8297 ~21.91 miles south of 63780
  • Affordable Rural property
  • Hotel has 92 rooms
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel
+1-888-906-6358
115 Hospitality Dr., Sikeston, MO 63801 +1-888-906-6358 ~21.92 miles south of 63780
  • 3 star Rural hotel
  • 73 rooms in property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hotel 7 Inn Anna in Anna
+1-888-749-6785
100 Richview Dr., Anna, IL 62906 +1-888-749-6785 ~25.02 miles northeast of 63780
  • Cheap hotel
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Dexter : 913 Outer Rd.
+1-888-878-9982
913 Outer Rd., Dexter, MO 63841 +1-888-878-9982 ~36.64 miles southwest of 63780
  • Economical property
  • Comp. Breakfast
From$60
Average 3.0 /5 Reviews Call BookMore Details
Travelodge by Wyndham Dexter - Dexter
+1-888-389-4485
1608 West Business U.s. 60, Dexter, MO 63841 +1-888-389-4485 ~37.34 miles southwest of 63780
  • Affordable hotel
From$67
Very Good 4.0 /5 Read Reviews Call BookMore Details
Train Inn in Carbondale
+1-888-389-4121
406 East Stoker St., Carbondale, IL 62901 +1-888-389-4121 ~41.10 miles north of 63780
  • Mid-scale Suburban hotel
  • 7 rooms in property
From$50
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino - Metropolis
+1-888-675-2083
100 East Front St., Metropolis, IL 62960 +1-888-675-2083 ~41.18 miles east of 63780
  • High-end property
  • Check in: 16:00
From$160
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Metropolis in Metropolis
+1-800-716-8490
203 East Front St., Metropolis, IL 62960 +1-800-716-8490 ~41.23 miles east of 63780
  • Economy Riverfront property
  • Gym / Fitness Center Available
From$45
Average 3.0 /5 Latest Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale
+1-800-805-5223
200 West Elm St., Carbondale, IL 62901 +1-800-805-5223 ~41.29 miles north of 63780
  • Affordable Downtown property
  • Check in time: 3:00 pm
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
University Inn of Carbondale in Carbondale
+1-888-965-1860
2400 West Main St., Carbondale, IL 62901 +1-888-965-1860 ~41.35 miles north of 63780
  • Affordable hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
Carbondale Value Inn & Suites
+1-888-788-5576
700 East Main St., Carbondale, IL 62901 +1-888-788-5576 ~41.77 miles north of 63780
  • Economy Downtown hotel
  • Check-in time: 3:00pm
From$54
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Carbondale
+1-888-897-9207
1180 East Main St., Carbondale, IL 62901 +1-888-897-9207 ~42.08 miles north of 63780
  • 2-star property
  • 3 floors in hotel
From$58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge - Metropolis
+1-888-311-4278
1415 East 5th St., Metropolis, IL 62960 +1-888-311-4278 ~42.28 miles east of 63780
  • Low Cost property
  • Check-in: 11:00
From$60
Not Good 1.0 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Paducah : 5006 Hinkleville Rd.
+1-888-469-4795
5006 Hinkleville Rd., Paducah, KY 42001 +1-888-469-4795 ~42.53 miles east of 63780
  • Cheap Suburban hotel
  • Fitness / Gym is on-site
From$55
Very Good 4.0 /5 Reviews Call BookMore Details
Best Western Saluki Inn
+1-888-734-9421
801 North Giant City Rd., Carbondale, IL 62902 +1-888-734-9421 ~42.55 miles north of 63780
  • Affordable Downtown hotel
  • Free complimentary breakfast
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale
+1-888-841-5292
128 East Walnut St., Murphysboro, IL 62966 +1-888-841-5292 ~42.58 miles north of 63780
  • 2-star property
  • 39 sleeping rooms in hotel
Quality Inn Carbondale University Area
+1-888-455-5160
1415 East Main St., Carbondale, IL 62901 +1-888-455-5160 ~42.65 miles north of 63780
  • Affordable Suburban hotel
  • Hotel has 2 floors
From$30
Poor 2.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Paducah
+1-888-965-8297
3900 Coleman Crossing Circle, Paducah, KY 42001 +1-888-965-8297 ~43.20 miles east of 63780
  • Mid-scale Suburban hotel
  • Free complimentary breakfast
From$89
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Carbondale
+1-888-906-6358
2175 Reed Station Pkwy., Carbondale, IL 62901 +1-888-906-6358 ~43.48 miles northeast of 63780
  • Affordable Rural property
  • 80 sleeping rooms in hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Metropolis : 2055 East 5th St.
+1-888-749-6785
2055 East 5th St., Metropolis, IL 62960 +1-888-749-6785 ~43.53 miles east of 63780
  • Economy Highway hotel
  • Hotel has 2 floors
From$60
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites Metropolis I-24 in Metropolis
+1-888-878-9982
2118 East 5th St., Metropolis, IL 62960 +1-888-878-9982 ~43.57 miles east of 63780
  • Affordable property
  • Check in: 11:00
From$80
Very Good 4.0 /5 Latest Reviews Call BookMore Details
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