Hotels in 77021 - Houston TX

Only hotels in 77021 zip code are listed below. Search for cheap and discount hotel rates in Houston, TX for your upcoming leisure or conference / group travel. We list the best 77021 hotels and motels so you can review the Houston hotel list below to find the perfect lodging. Hotels in Harris county and area code 713 are also listed.

77021 Hotels & Accommodations

Medical District : 2700 Old Spanish Trail
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2700 Old Spanish Trail, Houston, TX 77021 +1-888-389-4121
  • 4 star hotel
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From$75
Average 3.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Greenway Plaza : 2330 Southwest Frwy
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
2330 Southwest Frwy, Houston, TX 77098 +1-888-675-2083 ~1.05 miles west of 77021
  • 2-star Downtown property
  • Hotel has 122 rooms
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From$61
Average 3.0 /5 Guest Reviews Call BookMore Details
Summit Inn - Houston Medical Center - Houston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3138 Old Spanish Trail, Houston, TX 77054 +1-800-716-8490 ~1.23 miles west of 77021
  • 2 star property
  • 33 rooms in property
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Mainstay Suites Medical Center / Reliant Park
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3134 Old Spanish Trail, Houston, TX 77054 +1-800-805-5223 ~1.26 miles west of 77021
  • Low Cost Convention Center hotel
  • Access to gym on-site
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From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Cliù Luxury Boutique Condo Hotel in Houston
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3144 Southmore Blvd. Unit 10, Houston, TX 77004 +1-888-965-1860 ~1.44 miles north of 77021
  • Four star Downtown hotel
  • Hotel has 8 suites
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From$100
Average 3.0 /5 Recent Reviews Call BookMore Details
Hilton Garden
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
6840 B Almeda Rd., Houston, TX 77030 +1-888-788-5576 ~1.75 miles west of 77021
  • Affordable hotel
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Home2 Suites
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
6840 Almeda Rd., Houston, TX 77030 +1-888-897-9207 ~1.75 miles west of 77021
  • 3-star Suburban property
  • Check-in time: 3:00 PM
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From$99
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn : 6840b Almeda Rd.
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6840b Almeda Rd., Houston, TX 77030 +1-888-311-4278 ~1.75 miles west of 77021
  • Mid-scale Suburban hotel
  • Hotel has 157 rooms
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From$109
Average 3.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Medical Center Downtown
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2419 Riverside Dr., Houston, TX 77004 +1-888-469-4795 ~1.84 miles northwest of 77021
  • 2 star property
  • Check in: 15:00
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From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Hiton University of Houston : 4800 Calhoun Rd.
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4800 Calhoun Rd., Houston, TX 77004 +1-888-734-9421 ~2.00 miles northeast of 77021
  • High-end Downtown hotel
  • 8 floors in property
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From$125
Average 3.0 /5 Read Reviews Call BookMore Details
Best Way Inn Houston - Medical Center : 3100 Holmes Rd.
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3100 Holmes Rd., Houston, TX 77051 +1-888-841-5292 ~2.04 miles southwest of 77021
  • Low Cost hotel
  • 42 sleeping rooms in hotel
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Braeswood Bl
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1301 Braeswood Blvd., Houston, TX 77030 +1-888-455-5160 ~2.39 miles west of 77021
  • 3 star Convention Center hotel
  • Check-in time: 3:00pm
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From$64
Average 3.0 /5 Reviews Call BookMore Details
Blossom Houston Medical Center - Houston
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
7114 Bertner Ave., Houston, TX 77030 +1-888-965-8297 ~2.52 miles west of 77021
  • 3-star hotel
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From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Blossom Hotel Houston in Houston
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
7118 Bertner Ave., Houston, TX 77030 +1-888-906-6358 ~2.53 miles west of 77021
  • Four-star Convention Center hotel
  • Fitness / Gym is on-site
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From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Place
+1-888-749-6785

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New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
7329a Fannin St., Houston, TX 77030 +1-888-749-6785 ~2.59 miles west of 77021
  • Three Star hotel
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Hyatt House Houston Medical Center - Houston
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
7329 Fannin St., Houston, TX 77030 +1-888-878-9982 ~2.59 miles west of 77021
  • Three Star Suburban property
  • 298 sleeping rooms in hotel
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From$99
Average 3.0 /5 Recent Reviews Call BookMore Details
Sonder The Hampstead : 1508 Blodgett
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1508 Blodgett, Houston, TX 77004 +1-888-389-4485 ~2.61 miles northwest of 77021
  • 3-star Downtown property
  • Hotel has 4 floors
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Lexington Hotel Houston Medical Center
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1025 Swanson St., Houston, TX 77030 +1-888-389-4121 ~2.61 miles west of 77021
  • Two-star Downtown hotel
  • Check-in: 3:00 PM
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From$60
Average 3.5 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park : 1715 Old Spanish Trail
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1715 Old Spanish Trail, Houston, TX 77054 +1-888-675-2083 ~2.71 miles west of 77021
  • 3 star Convention Center property
  • Fitness center on property
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From$69
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel Zaza Houston Museum District
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5701 Main St., Houston, TX 77005 +1-800-716-8490 ~2.75 miles northwest of 77021
  • 4-star Downtown property
  • Check in: 4:00 PM
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From$159
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin - Houston
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7979 Fannin, Houston, TX 77054 +1-800-805-5223 ~2.75 miles west of 77021
  • Economical Convention Center hotel
  • Check in time: 3pm
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From$49
Poor 2.5 /5 Review Score Call BookMore Details
Houston Marriott Medical Center/Museum District : 6580 Fannin St.
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
6580 Fannin St., Houston, TX 77030 +1-888-965-1860 ~2.77 miles west of 77021
  • Four-star Downtown property
  • 26 floors in hotel
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From$75
Very Good 4.5 /5 Recent Reviews Call BookMore Details
The Westin Hou Medical Center - Houston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1709 Dryden Rd., Houston, TX 77030 +1-888-788-5576 ~2.77 miles west of 77021
  • 3 star property
  • Check in: 15:00
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From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Scott Inn Suites Downtown Houston - Houston
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1933 Scott St., Houston, TX 77003 +1-888-897-9207 ~2.82 miles north of 77021
  • 3-star hotel
  • Check-in: 15:00
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From$90
Very Good 4.0 /5 Guest Reviews Call BookMore Details
SureStay Plus by Best Western Houston Medical Center - Houston
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6700 Main St., Houston, TX 77030 +1-888-311-4278 ~2.88 miles west of 77021
  • Three Star Downtown property
  • Comp. Breakfast
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From$57
Average 3.5 /5 Review Score Call BookMore Details
InterContinental Houston, an IHG Hotel
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
6750 Main St., Houston, TX 77030 +1-888-469-4795 ~2.91 miles west of 77021
  • 4-star Downtown property
  • Fitness + Health Center
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From$75
Average 3.0 /5 Reviews Call BookMore Details
Doubletree by Hilton Houston Medical Center Hotel & Suites in Houston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
6800 Main St., Houston, TX 77030 +1-888-734-9421 ~2.94 miles west of 77021
  • Mid-scale Downtown property
  • 40 rooms in property
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Downtown / University of Houston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
6190 Gulf Freeway, Houston, TX 77023 +1-888-841-5292 ~2.99 miles east of 77021
  • 3 star Downtown property
  • Comp. Breakfast
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From$55
Average 3.0 /5 Read Reviews Call BookMore Details
Springhill Suites Marriott Medical Center Nrg Park - Houston
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1400 Old Spanish Trail, Houston, TX 77054 +1-888-455-5160 ~3.11 miles west of 77021
  • Three Star Downtown property
  • Free complimentary breakfast
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From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Bayou City Event Center
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
9401 Knight Rd., Houston, TX 77045 +1-888-965-8297 ~3.15 miles southwest of 77021
  • 2 star hotel
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Sonder at Mid Main
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3550 Main St., Houston, TX 77002 +1-888-906-6358 ~3.20 miles north of 77021
  • 3-star Downtown property
  • 26 sleeping rooms in hotel
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From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center, an IHG Hotel - Houston
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8111 Kirby Dr., Houston, TX 77054 +1-888-749-6785 ~3.27 miles west of 77021
  • 3-star Suburban hotel
  • Hotel has 238 rooms
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From$126
Average 3.5 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1303 La Concha Ln, Houston, TX 77054 +1-888-878-9982 ~3.29 miles west of 77021
  • Inexpensive Convention Center hotel
  • 84 rooms in property
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From$41
Average 3.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Houston Medical Center/NRG Park in Houston
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
Houston Medical Center 7702 Main St., Houston, TX 77030 +1-888-389-4485 ~3.29 miles west of 77021
  • Midscale Suburban hotel
  • Hotel has 3 meeting rooms
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From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
The Reside in Houston
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
7755 South Main St., Houston, TX 77054 +1-888-389-4121 ~3.32 miles west of 77021
  • 3 star Downtown hotel
  • Hotel has 3 floors
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From$55
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
7807 Kirby Dr., Houston, TX 77030 +1-888-675-2083 ~3.36 miles west of 77021
  • Affordable Downtown property
  • Gym is available on property
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From$109
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Houston Medical Center/NRG Park : 7702 Main St.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
7702 Main St., Houston, TX 77030 +1-800-716-8490 ~3.37 miles west of 77021
  • 3-star Downtown hotel
  • 197 rooms in property
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Moody Manor
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7706 Main St., Houston, TX 77030 +1-800-805-5223 ~3.39 miles west of 77021
  • Mid-scale Downtown hotel
  • 2 floors in hotel
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From$69
Average 3.5 /5 Guest Reviews Call BookMore Details
Americas Best Value Inn NRG Park Medical Center
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7905 South Main St., Houston, TX 77025 +1-888-965-1860 ~3.43 miles west of 77021
  • 2-star Suburban property
  • 70 rooms in hotel
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From$72
Average 3.0 /5 Read Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
8600 Kirby Dr., Houston, TX 77054 +1-888-788-5576 ~3.48 miles west of 77021
  • Mid-scale Convention Center property
  • Gym / Fitness Center Available
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From$80
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Hotel Ylem
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
8080 South Main St., Houston, TX 77025 +1-888-897-9207 ~3.51 miles west of 77021
  • Affordable Downtown property
  • 2 conference rooms in property
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Rodeway Inn & Suites Houston near Medical Center in Houston
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6712 Morningside Dr., Houston, TX 77030 +1-888-311-4278 ~3.51 miles west of 77021
  • Low Cost Downtown property
  • 33 sleeping rooms in hotel
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Houston-Downtown Conv Ctr, an
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1810 Bell St., Houston, TX 77003 +1-888-469-4795 ~3.55 miles north of 77021
  • Three Star Downtown property
  • Fitness / Gym is on-site
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From$108
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Wyndham Houston near NRG Park/Medical Center : 8686 Kirby Dr.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
8686 Kirby Dr., Houston, TX 77054 +1-888-734-9421 ~3.56 miles west of 77021
  • Affordable Convention Center hotel
  • 393 rooms in hotel
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From$75
Average 3.0 /5 Reviews Call BookMore Details
Comfort Suites near Texas Medical Center - NRG Stadium in Houston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1055 Mcnee Rd., Houston, TX 77054 +1-888-841-5292 ~3.59 miles west of 77021
  • Midscale Convention Center property
  • 3 floors in property
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From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel Saint Augustine : 4110 Loretto Dr.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4110 Loretto Dr., Houston, TX 77006 +1-888-455-5160 ~3.62 miles northwest of 77021
  • 4-star Downtown property
  • 2 floors in hotel
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From$250
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites NRG Park - Medical Center : 2364 South Loop West
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2364 South Loop West, Houston, TX 77054 +1-888-965-8297 ~3.64 miles west of 77021
  • Cheap Highway property
  • Hotel has 21 suites
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From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
La Colombe D Or Hotel - Houston
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3410 Montrose Blvd., Houston, TX 77006 +1-888-906-6358 ~3.68 miles northwest of 77021
  • 3 star hotel
  • Check-in: 16:00
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From$90
Average 3.0 /5 Latest Reviews Call BookMore Details
Sonder Nrg Park : 8700 South Main St.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8700 South Main St., Houston, TX 77025 +1-888-749-6785 ~3.73 miles west of 77021
  • Three Star Downtown property
  • 21 sleeping rooms in hotel
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From$85
Average 3.0 /5 Guest Reviews Call BookMore Details
Staybridge Suites Houston - Medical Center, an IHG Hotel in Houston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
9000 South Main St., Houston, TX 77025 +1-888-878-9982 ~3.78 miles west of 77021
  • Mid-scale Downtown hotel
  • Fitness / Gym is on-site
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From$83
Average 3.0 /5 Review Score Call BookMore Details
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