Hotels in 77021 - Houston TX

Only hotels in 77021 zip code are listed below. Search for cheap and discount hotel rates in Houston, TX for your upcoming leisure or conference / group travel. We list the best 77021 hotels and motels so you can review the Houston hotel list below to find the perfect lodging. Hotels in Harris county and area code 713 are also listed.

77021 Hotels/Motels & Accommodations

Medical District - Houston
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2700 Old Spanish Trail, Houston, TX 77021 +1-888-389-4121
  • Four star property
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From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Greenway Plaza : 2330 Southwest Frwy
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
2330 Southwest Frwy, Houston, TX 77098 +1-888-675-2083 ~1.05 miles west of 77021
  • Economy Downtown property
  • 122 rooms in property
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From$61
Average 3.0 /5 Latest Reviews Call BookMore Details
Summit Inn - Houston Medical Center : 3138 Old Spanish Trail
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3138 Old Spanish Trail, Houston, TX 77054 +1-800-716-8490 ~1.23 miles west of 77021
  • Two star hotel
  • Hotel has 33 rooms
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Mainstay Suites Medical Center / Reliant Park in Houston
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
3134 Old Spanish Trail, Houston, TX 77054 +1-800-805-5223 ~1.26 miles west of 77021
  • 2 star Convention Center property
  • Check-in time: 11:00
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From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Cliù Luxury Boutique Condo Hotel - Houston
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
3144 Southmore Blvd. Unit 10, Houston, TX 77004 +1-888-965-1860 ~1.44 miles north of 77021
  • 4 star Downtown property
  • Check in: 4:00pm CST
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From$100
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Garden
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
6840 B Almeda Rd., Houston, TX 77030 +1-888-788-5576 ~1.75 miles west of 77021
  • 3 star property
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From$80
Average 3.0 /5 Reviews Call BookMore Details
Home2 Suites in Houston
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
6840 Almeda Rd., Houston, TX 77030 +1-888-897-9207 ~1.75 miles west of 77021
  • 3-star Suburban property
  • Free comp. breakfast
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From$99
Excellent 5.0 /5 Review Score Call BookMore Details
Hilton Garden Inn
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6840b Almeda Rd., Houston, TX 77030 +1-888-311-4278 ~1.75 miles west of 77021
  • 3-star Suburban hotel
  • 10 floors in hotel
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From$109
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Medical Center Downtown - Houston
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2419 Riverside Dr., Houston, TX 77004 +1-888-469-4795 ~1.84 miles northwest of 77021
  • Inexpensive hotel
  • 2 floors in hotel
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From$60
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton University of Houston
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4800 Calhoun Rd., Houston, TX 77004 +1-888-734-9421 ~2.00 miles northeast of 77021
  • Expensive Downtown hotel
  • Comp. Breakfast
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From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Way Inn Houston - Medical Center : 3100 Holmes Rd.
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
3100 Holmes Rd., Houston, TX 77051 +1-888-841-5292 ~2.04 miles southwest of 77021
  • Economy hotel
  • Hotel has 42 rooms
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr Braeswood Bl : 1301 Braeswood Blvd.
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1301 Braeswood Blvd., Houston, TX 77030 +1-888-455-5160 ~2.39 miles west of 77021
  • Affordable Convention Center hotel
  • 130 rooms in property
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From$64
Average 3.0 /5 Latest Reviews Call BookMore Details
Blossom Houston Medical Center
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
7114 Bertner Ave., Houston, TX 77030 +1-888-965-8297 ~2.52 miles west of 77021
  • 3-star hotel
  • Check-in time: 16:00
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From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Blossom Hotel Houston in Houston
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
7118 Bertner Ave., Houston, TX 77030 +1-888-906-6358 ~2.53 miles west of 77021
  • High end Convention Center property
  • Hotel has 12 meeting rooms
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From$99
Average 3.0 /5 Review Score Call BookMore Details
Hyatt Place
+1-888-749-6785

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New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
7329a Fannin St., Houston, TX 77030 +1-888-749-6785 ~2.59 miles west of 77021
  • Mid-scale hotel
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Hyatt Place Hyatt House Houston Medical Center in Houston
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
7329 Fannin St., Houston, TX 77030 +1-888-878-9982 ~2.59 miles west of 77021
  • 3 star Suburban property
  • 129 suites in hotel
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From$99
Average 3.0 /5 Reviews Call BookMore Details
Sonder The Hampstead in Houston
+1-888-389-4485

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New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1508 Blodgett, Houston, TX 77004 +1-888-389-4485 ~2.61 miles northwest of 77021
  • 3 star Downtown property
  • 4 floors in hotel
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Lexington Hotel Houston Medical Center
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1025 Swanson St., Houston, TX 77030 +1-888-389-4121 ~2.61 miles west of 77021
  • Low priced Downtown hotel
  • Check in time: 3:00 PM
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From$60
Average 3.5 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Houston Medical Center Nrg Park
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1715 Old Spanish Trail, Houston, TX 77054 +1-888-675-2083 ~2.71 miles west of 77021
  • Affordable Convention Center hotel
  • Check in: 3:00PM
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From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hotel Zaza Houston Museum District
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5701 Main St., Houston, TX 77005 +1-800-716-8490 ~2.75 miles northwest of 77021
  • Four star Downtown hotel
  • Hotel has 75 suites
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From$159
Very Good 4.5 /5 Reviews Call BookMore Details
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7979 Fannin, Houston, TX 77054 +1-800-805-5223 ~2.75 miles west of 77021
  • Cheap Convention Center hotel
  • 3 floors in hotel
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From$49
Poor 2.5 /5 Recent Reviews Call BookMore Details
Houston Marriott Medical Center/Museum District in Houston
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
6580 Fannin St., Houston, TX 77030 +1-888-965-1860 ~2.77 miles west of 77021
  • Four-star Downtown property
  • Gym / Fitness Center Available
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From$75
Very Good 4.5 /5 Guest Reviews Call BookMore Details
The Westin Hou Medical Center - Houston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1709 Dryden Rd., Houston, TX 77030 +1-888-788-5576 ~2.77 miles west of 77021
  • Mid-scale hotel
  • Check-in: 15:00
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From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
Scott Inn Suites Downtown Houston
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1933 Scott St., Houston, TX 77003 +1-888-897-9207 ~2.82 miles north of 77021
  • 3 star hotel
  • 18 rooms in hotel
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From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Houston Medical Center Hotel
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6700 Main St., Houston, TX 77030 +1-888-311-4278 ~2.88 miles west of 77021
  • Three Star Downtown hotel
  • Hotel has 25 suites
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From$115
Average 3.5 /5 Guest Reviews Call BookMore Details
InterContinental Houston by IHG
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
6750 Main St., Houston, TX 77030 +1-888-469-4795 ~2.91 miles west of 77021
  • Four star Downtown property
  • Hotel has 37 suites
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From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
Doubletree by Hilton Houston Medical Center Hotel & Suites : 6800 Main St.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
6800 Main St., Houston, TX 77030 +1-888-734-9421 ~2.94 miles west of 77021
  • Affordable Downtown hotel
  • Gym is available on property
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Downtown / University of Houston - Houston
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
6190 Gulf Freeway, Houston, TX 77023 +1-888-841-5292 ~2.99 miles east of 77021
  • Midscale Downtown hotel
  • Hotel has 2 floors
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From$55
Average 3.0 /5 Reviews Call BookMore Details
SpringHill Suites Houston Medical Center/NRG Park
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1400 Old Spanish Trail, Houston, TX 77054 +1-888-455-5160 ~3.11 miles west of 77021
  • 3 star Downtown property
  • 190 rooms in property
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Bayou City Event Center
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
9401 Knight Rd., Houston, TX 77045 +1-888-965-8297 ~3.15 miles southwest of 77021
  • 2 star hotel
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Sonder at Mid Main - Houston
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3550 Main St., Houston, TX 77002 +1-888-906-6358 ~3.20 miles north of 77021
  • 3-star Downtown hotel
  • 26 sleeping rooms in hotel
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From$75
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Houston S - Nrg Area - Medical Center by IHG - Houston
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8111 Kirby Dr., Houston, TX 77054 +1-888-749-6785 ~3.27 miles west of 77021
  • Affordable Suburban hotel
  • 11 floors in hotel
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From$126
Average 3.5 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Houston Med Ctr NRG Park Kirby - Houston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1303 La Concha Ln, Houston, TX 77054 +1-888-878-9982 ~3.29 miles west of 77021
  • 2 star Convention Center property
  • Free breakfast available
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From$41
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Houston Medical Center/NRG Park : Houston Medical Center 7702 Main St.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
Houston Medical Center 7702 Main St., Houston, TX 77030 +1-888-389-4485 ~3.29 miles west of 77021
  • Mid-scale Suburban property
  • Gym / Fitness Center Available
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From$69
Very Good 4.0 /5 Reviews Call BookMore Details
The Reside : 7755 South Main St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
7755 South Main St., Houston, TX 77054 +1-888-389-4121 ~3.32 miles west of 77021
  • Midscale Downtown property
  • Hotel has 36 rooms
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From$55
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Residence Inn Houston Medical Center / Nrg Park
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
7807 Kirby Dr., Houston, TX 77030 +1-888-675-2083 ~3.36 miles west of 77021
  • Affordable Downtown hotel
  • 182 rooms in hotel
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From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Houston Medical Center / Nrg Park - Houston
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
7702 Main St., Houston, TX 77030 +1-800-716-8490 ~3.37 miles west of 77021
  • 3 star Downtown property
  • 197 rooms in hotel
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Moody Manor
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7706 Main St., Houston, TX 77030 +1-800-805-5223 ~3.39 miles west of 77021
  • Mid-scale Downtown hotel
  • Check-in: 3:00pm
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From$69
Average 3.5 /5 Review Score Call BookMore Details
Americas Best Value Inn NRG Park Medical Center
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
7905 South Main St., Houston, TX 77025 +1-888-965-1860 ~3.43 miles west of 77021
  • 2 star Suburban property
  • Check in time: 3pm
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From$72
Average 3.0 /5 Read Reviews Call BookMore Details
Wingate by Wyndham Near Nrg Park / Medical Center in Houston
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
8600 Kirby Dr., Houston, TX 77054 +1-888-788-5576 ~3.48 miles west of 77021
  • 3-star Convention Center property
  • 2 conference rooms in property
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From$80
Poor 2.0 /5 Guest Reviews Call BookMore Details
Hotel Ylem
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
8080 South Main St., Houston, TX 77025 +1-888-897-9207 ~3.51 miles west of 77021
  • Affordable Downtown property
  • Hotel has 3 floors
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Rodeway Inn & Suites Houston near Medical Center : 6712 Morningside Dr.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6712 Morningside Dr., Houston, TX 77030 +1-888-311-4278 ~3.51 miles west of 77021
  • Two star Downtown property
  • 33 rooms in property
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Hotel & Suites Houston-Downtown Conv Ctr by I - Houston
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1810 Bell St., Houston, TX 77003 +1-888-469-4795 ~3.55 miles north of 77021
  • 3-star Downtown property
  • Has environment-friendly policy See policy
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From$108
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Wyndham Houston near NRG Park/Medical Center in Houston
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
8686 Kirby Dr., Houston, TX 77054 +1-888-734-9421 ~3.56 miles west of 77021
  • 3-star Convention Center hotel
  • Check-in time: 3PM
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From$75
Average 3.0 /5 Reviews Call BookMore Details
Comfort Suites near Texas Medical Center - NRG Stadium : 1055 Mcnee Rd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1055 Mcnee Rd., Houston, TX 77054 +1-888-841-5292 ~3.59 miles west of 77021
  • Midscale Convention Center property
  • Access to gym on-site
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hotel Saint Augustine : 4110 Loretto Dr.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4110 Loretto Dr., Houston, TX 77006 +1-888-455-5160 ~3.62 miles northwest of 77021
  • Expensive Downtown hotel
  • Check-in: 3:00 PM
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From$401
Average 3.0 /5 Recent Reviews Call BookMore Details
Wanderstay Boutique Hotel
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
520 Sampson St., Houston, TX 77003 +1-888-965-8297 ~3.64 miles north of 77021
  • Four star hotel
  • 10 sleeping rooms in hotel
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From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites NRG Park - Medical Center in Houston
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2364 South Loop West, Houston, TX 77054 +1-888-906-6358 ~3.64 miles west of 77021
  • Low priced Highway property
  • Check-in: 3:00 pm
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
La Colombe D Or Hotel - Houston
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3410 Montrose Blvd., Houston, TX 77006 +1-888-749-6785 ~3.68 miles northwest of 77021
  • 3-star property
  • 15 sleeping rooms in hotel
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From$90
Average 3.0 /5 Guest Reviews Call BookMore Details
Sonder Nrg Park
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
8700 South Main St., Houston, TX 77025 +1-888-878-9982 ~3.73 miles west of 77021
  • Three Star Downtown property
  • 6 floors in property
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From$85
Average 3.0 /5 Read Reviews Call BookMore Details
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