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45621 Hotels, Motels & Accommodations

Quality Inn : 605 East Main St.
+1-888-389-4121
605 East Main St., Jackson, OH 45640 ~5.14 miles south of 45621
  • Mid-scale hotel
  • Check in: 15:00
From$90
Average 3.0 /5 Reviews Call BookMore Details
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Red Roof Inn Jackson, OH : 1000 Acy Ave.
+1-888-675-2083
1000 Acy Ave., Jackson, OH 45640 ~5.29 miles south of 45621
  • Two star Rural hotel
  • 62 rooms in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Jackson in Jackson
+1-800-716-8490
972 East Main St., Jackson, OH 45640 ~5.30 miles south of 45621
  • Cheap Rural property
  • Free complimentary breakfast
From$84
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn - Piketon
+1-800-805-5223
7525 Us 23, Piketon, OH 45661 ~21.75 miles west of 45621
  • Three Star Lake hotel
  • 70 rooms in property
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Chillicothe - Chillicothe
+1-888-965-1860
1135 East Main St., Chillicothe, OH 45601 ~23.81 miles northwest of 45621
  • Inexpensive Highway property
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Chillicothe East, an IHG Hotel : 1003 East Main St.
+1-888-788-5576
1003 East Main St., Chillicothe, OH 45601 ~23.89 miles northwest of 45621
  • Affordable Suburban property
  • 3 floors in property
From$87
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Christopher Inn and Suites : 30 North Plaza Blvd.
+1-888-897-9207
30 North Plaza Blvd., Chillicothe, OH 45601 ~25.45 miles northwest of 45621
  • Mid-scale Highway property
  • 7 suites in hotel
From$85
Very Good 4.5 /5 Read Reviews Call BookMore Details
Quality Inn
+1-888-311-4278
20 North Plaza Blvd., Chillicothe, OH 45601 ~25.47 miles northwest of 45621
  • Affordable Highway hotel
  • Check in: 12:00
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn and Suites by Marriott Chillicothe
+1-888-469-4795
300 North Plaza Blvd., Chillicothe, OH 45601 ~25.49 miles northwest of 45621
  • Three Star hotel
  • Check-in time: 03:00 p.m.
From$125
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Chillicothe : 100 North Plaza Blvd.
+1-888-734-9421
100 North Plaza Blvd., Chillicothe, OH 45601 ~25.62 miles northwest of 45621
  • Three Star Rural property
  • 22 suites in hotel
From$135
Very Good 4.0 /5 Read Reviews Call BookMore Details
Best Western Adena Inn - Chillicothe
+1-888-841-5292
1250 North Bridge St., Chillicothe, OH 45601 ~25.92 miles northwest of 45621
  • Cheap Downtown property
  • Hotel has 2 floors
From$92
Very Good 4.0 /5 Reviews Call BookMore Details
Travelodge by Wyndham Gallipolis - Gallipolis
+1-888-455-5160
260 Jackson Pike, Gallipolis, OH 45631 ~27.40 miles southeast of 45621
  • Inexpensive Rural property
  • Hotel has 45 rooms
From$53
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites in Portsmouth
+1-888-965-8297
5100 Scioto Trail, Portsmouth, OH 45662 ~29.71 miles southwest of 45621
  • Low-priced hotel
  • 2 floors in property
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Inn in Wheelersburg
+1-888-906-6358
8226 Ohio River Rd., Wheelersburg, OH 45694 ~29.77 miles southwest of 45621
  • 2-star property
  • 52 rooms in property
From$60
Average 3.0 /5 Review Score Call BookMore Details
Red Roof Inn Portsmouth - Wheelersburg
+1-888-749-6785
8340 Ohio River Rd., Wheelersburg, OH 45694 ~29.98 miles southwest of 45621
  • Cheap Highway hotel
  • Check-in time: 3:00 PM
From$71
Very Good 4.0 /5 Guest Reviews Call BookMore Details
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Super 8 by Wyndham Portsmouth : 4266 Us Route 23 North
+1-888-878-9982
4266 Us Route 23 North, Portsmouth, OH 45622 ~29.99 miles southwest of 45621
  • Two star Rural hotel
  • Hotel has 4 suites
From$54
Average 3.0 /5 Latest Reviews Call BookMore Details
Rodeway Inn & Suites
+1-888-389-4485
3762 Us Highway 23, Portsmouth, OH 45662 ~30.33 miles southwest of 45621
  • Economical hotel
  • Check in time: 1400
Ohio University Inn & Conference Center : 331 Richland Ave.
+1-888-389-4121
331 Richland Ave., Athens, OH 45701 ~30.56 miles east of 45621
  • Affordable Suburban hotel
  • Check-in time: 3:00 PM
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Logan An Ihg Hotel - Logan
+1-888-675-2083
12916 Grey St., Logan, OH 43138 ~30.82 miles north of 45621
  • Three Star Rural hotel
  • Check in: 03:00PM
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Sleep Inn Logan Ohio-Hocking Hills in Logan
+1-800-716-8490
12830 Grey St., Logan, OH 43138 ~30.96 miles north of 45621
  • 2-star hotel
  • 39 sleeping rooms in hotel
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Logan
+1-800-805-5223
12819 Oh 664, Logan, OH 43138 ~31.09 miles north of 45621
  • Affordable Rural property
  • 2 floors in hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn in Gallipolis
+1-888-965-1860
577 State Route 7n, Gallipolis, OH 45631 ~31.17 miles southeast of 45621
  • Affordable property
  • Fitness + Health Center
From$66
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn Gallipolis in Gallipolis
+1-888-788-5576
444 State Route 7 South, Gallipolis, OH 45631 ~31.26 miles southeast of 45621
  • Affordable Rural property
  • Fitness + Health Center
From$105
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 Gallipolis / Pt Pleasant in Gallipolis
+1-888-897-9207
321 Upper River Rd., Gallipolis, OH 45631 ~31.32 miles southeast of 45621
  • Two star Highway property
  • Hotel has 3 floors
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Athens - Athens
+1-888-311-4278
330 Columbus Rd., Athens, OH 45701 ~31.91 miles northeast of 45621
  • Inexpensive Rural property
  • Check-in: 3pm
Quality Inn
+1-888-469-4795
20 Home St., Athens, OH 45701 ~32.20 miles east of 45621
  • Mid-scale Rural property
  • Check in time: 15:00
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Athens, an IHG Hotel - Athens
+1-888-734-9421
555 East State St., Athens, OH 45701 ~32.49 miles east of 45621
  • Affordable Downtown hotel
  • 80 sleeping rooms in hotel
From$75
Very Good 4.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Athens
+1-888-841-5292
924 East State St., Athens, OH 45701 ~32.90 miles east of 45621
  • 3 star Rural hotel
  • Check in time: 3:00pm
From$169
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Knights Inn Athens in Athens
+1-888-455-5160
997 East State St., Athens, OH 45701 ~33.51 miles east of 45621
  • Economy Rural hotel
  • Free breakfast available
Holiday Inn Portsmouth Downtown, an IHG Hotel in Portsmouth
+1-888-965-8297
711 2nd St., Portsmouth, OH 45662 ~33.57 miles southwest of 45621
  • 3 star Downtown property
  • Hotel has 88 rooms
From$107
Very Good 4.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Athens in Athens
+1-888-906-6358
2091 East State St., Athens, OH 45701 ~34.55 miles east of 45621
  • Economy property
  • 53 rooms in property
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites : 24517 Us Highway 23s
+1-888-749-6785
24517 Us Highway 23s, Circleville, OH 43113 ~36.60 miles northwest of 45621
  • Low Cost Rural hotel
  • Hotel has 59 rooms
From$89
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Circleville
+1-888-878-9982
1520 South Court St., Circleville, OH 45113 ~37.03 miles northwest of 45621
  • 3 star property
  • 87 rooms in property
From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Circleville An Ihg Hotel : 23911 Us 23
+1-888-389-4485
23911 Us 23, Circleville, OH 43113 ~37.19 miles northwest of 45621
  • 3 star Rural property
  • Has environment-friendly policy See more
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Rodeway Inn - Circleville
+1-888-389-4121
23897 Us Route 23 South, Circleville, OH 43113 ~37.23 miles northwest of 45621
  • Economical property
  • 70 sleeping rooms in hotel
Holiday Inn Express & Suites Ironton An Ihg Hotel
+1-888-675-2083
401 South 9th St., Ironton, OH 45638 ~40.03 miles south of 45621
  • Affordable Suburban property
  • 3 floors in hotel
From$85
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites by Marriott Ironton : 802 Washington St.
+1-800-716-8490
802 Washington St., Ironton, OH 45638 ~40.06 miles south of 45621
  • Expensive Downtown property
  • Hotel has an eco-friendly policy Read more
From$75
Poor 2.0 /5 Reviews Call BookMore Details
Shawnee Lodge & Conference Center - West Portsmouth
+1-800-805-5223
4404b State Route 125, West Portsmouth, OH 45663 ~40.96 miles southwest of 45621
  • 3-star Rural property
  • 50 sleeping rooms in hotel
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Burr Oak Lodge & Conference Center : 10660 Burr Oak Lodge Rd.
+1-888-965-1860
10660 Burr Oak Lodge Rd., Glouster, OH 45732 ~42.21 miles northeast of 45621
  • Expensive hotel
  • Check in: 15:30
From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Best Western River Cities : 31 Russell Plaza Dr.
+1-888-788-5576
31 Russell Plaza Dr., Ashland, KY 41101 ~42.64 miles south of 45621
  • Midscale Downtown hotel
  • Check-in: 3:00pm
From$89
Very Good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Lancaster : 2041 Schorrway Dr.
+1-888-897-9207
2041 Schorrway Dr., Lancaster, OH 43130 ~42.91 miles north of 45621
  • Midscale Suburban hotel
  • Gym is available on property
From$79
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites
+1-888-311-4278
1861 Riverway Dr., Lancaster, OH 43130 ~42.97 miles north of 45621
  • 3-star property
  • 15 suites in hotel
From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Lancaster
+1-888-469-4795
1721 River Valley Circle North, Lancaster, OH 43130 ~43.00 miles north of 45621
  • Two-star property
  • Check in time: 12:00 PM
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Delta Hotels by Marriott Ashland Downtown in Ashland
+1-888-734-9421
1441 Winchester Ave., Ashland, KY 41101 ~43.80 miles south of 45621
  • Four star Downtown hotel
  • Has environment-friendly policy See policy
From$75
Average 3.0 /5 Reviews Call BookMore Details

Next: Show All Available 45621 Hotels with Pricing

Graph: Next 20 Days of Jackson Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Jackson, OH discounts available. The chart reflects the cheapest Jackson hotel for each day and each star rating category.

FAQs about hotels near 45621

What are the top reviewed hotels near 45621?

Christopher Inn and Suites, Comfort Inn and Holiday Inn Express Chillicothe East, an IHG Hotel are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 45621?

Towneplace Suites by Marriott Ironton, Burr Oak Lodge & Conference Center and Delta Hotels by Marriott Ashland Downtown are the top 3 luxury hotels near 45621.

What hotels are closest to the area of 45621?

Quality Inn, Red Roof Inn Jackson, OH, and Days Inn by Wyndham Jackson are the properties closest to 45621.

How much does a 3 star hotel near 45621 cost per night?

In the last year, the average 3 star hotel near 45621 has been $95.00 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 45621?

Christopher Inn and Suites, Ohio University Inn & Conference Center and Burr Oak Lodge & Conference Center are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45621?

Fairfield Inn and Suites by Marriott Chillicothe, Fairfield Inn & Suites Athens and Towneplace Suites by Marriott Ironton are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 45621?

Comfort Inn, Quality Inn and Quality Inn & Suites are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best Best Western hotels near 45621?

Best Western Adena Inn and Best Western River Cities are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels near 45621?

Holiday Inn Express Chillicothe East, an IHG Hotel, Holiday Inn Express Logan An Ihg Hotel and Holiday Inn Express Hotel & Suites Athens, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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