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45221 Hotels/Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area - Cincinnati
+1-888-389-4121
2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • Affordable Rural property
  • 6 floors in property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel
+1-888-675-2083
310 Straight St., Cincinnati, OH 45219 ~0.29 miles west of 45221
  • 4-star Suburban property
  • 7 floors in hotel
From$129
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati/Uptown-University Area in Cincinnati
+1-800-716-8490
3024 Vine St., Cincinnati, OH 45219 ~0.47 miles northeast of 45221
  • 3 star Suburban property
  • Gym / Fitness Center Available
From$110
Very Good 4.0 /5 Read Reviews Call BookMore Details
Graduate by Hilton Cincinnati
+1-800-805-5223
151 Goodman Dr., Cincinnati, OH 45219 ~0.62 miles northeast of 45221
  • High-end Downtown property
  • Hotel has 203 rooms
From$75
Very Good 4.0 /5 Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati
+1-888-965-1860
2347 Reading Rd., Cincinnati, OH 45202 ~0.85 miles east of 45221
  • 2 star Downtown hotel
  • Hotel has 7 floors
From$89
Average 3.0 /5 Guest Reviews Call BookMore Details
Springhill Suites Midtown Cincinnati - Cincinnati
+1-888-788-5576
610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • 3 star Downtown property
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
voco The Clair Cincinnati Downtown, an IHG Hotel
+1-888-897-9207
701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 ~1.83 miles south of 45221
  • 3 star Downtown hotel
  • Check-in time: 3:00pm
From$144
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown - Cincinnati
+1-888-311-4278
106 West 7th St., Cincinnati, OH 45202 ~1.84 miles south of 45221
  • Mid-scale Downtown hotel
  • Check in time: 3:00PM
From$100
Excellent 5.0 /5 Review Score Call BookMore Details
The Guild Downtown | Vine Street - Cincinnati
+1-888-469-4795
642 Vine St., Cincinnati, OH 45202 ~1.86 miles south of 45221
  • Midscale Downtown property
  • Fitness center on property
From$80
Average 3.0 /5 Review Score Call BookMore Details
Kinley Cincinnati Hotel - Cincinnati
+1-888-734-9421
636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • 4-star Downtown hotel
  • Check in time: 12:00 PM
From$149
Average 3.0 /5 Read Reviews Call BookMore Details
Kinley Cincinnati Downtown
+1-888-841-5292
636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • High-end Downtown property
  • Hotel has an eco-friendly policy Read more
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
21c Museum Hotel Cincinnati
+1-888-455-5160
609 Walnut St., Cincinnati, OH 45202 ~1.88 miles south of 45221
  • 4-star Downtown hotel
  • 10 floors in hotel
From$160
Very Good 4.5 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown : 617b Vine St.
+1-888-965-8297
617b Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Affordable Downtown property
  • Free breakfast available
From$111
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati-Downtown
+1-888-906-6358
617 Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Three Star Downtown property
  • Hotel has 72 suites
From$91
Average 3.0 /5 Read Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton
+1-888-749-6785
601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • Four star Downtown hotel
  • Check in: 4pm
From$95
Average 3.0 /5 Review Score Call BookMore Details
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Quality Inn & Suites Cincinnati Downtown in Cincinnati
+1-888-878-9982
800 West 8th St., Cincinnati, OH 45203 ~1.98 miles south of 45221
  • Two star Downtown property
  • 6 meeting rooms in property
From$46
Average 3.0 /5 Read Reviews Call BookMore Details
Millennium Cincinnati : 150 West 5th St.
+1-888-389-4485
150 West 5th St., Cincinnati, OH 45202 ~1.98 miles south of 45221
  • 3 star Downtown hotel
  • Gym / Fitness Center Available
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza - Cincinnati
+1-888-389-4121
35 West 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • Four star Downtown hotel
  • Fitness + Health Center
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Westin Cincinnati
+1-888-675-2083
21 East 5th St., Cincinnati, OH 45202 ~2.04 miles south of 45221
  • Three Star Downtown property
  • 17 floors in hotel
From$129
Average 3.0 /5 Recent Reviews Call BookMore Details
Hyatt Regency Cincinnati : 151 West 5th St.
+1-800-716-8490
151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • Four-star Downtown property
  • 26 conference rooms in property
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps in Cincinnati
+1-800-805-5223
506 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • 4-star hotel
  • 134 rooms in property
From$160
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown - Cincinnati
+1-888-965-1860
6 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • 3 star Downtown hotel
  • Fitness center on property
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel
+1-888-788-5576
36 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Four-star Downtown property
  • 40 suites in hotel
From$139
Very Good 4.0 /5 Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection - Cincinnati
+1-888-897-9207
311 Pike St., Cincinnati, OH 45202 ~2.11 miles south of 45221
  • Luxurious 5-star property
  • Hotel has 2 suites
From$289
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites in Cincinnati
+1-888-311-4278
130 West Mitchell Ave., Cincinnati, OH 45217 ~2.25 miles north of 45221
  • 3 star Downtown property
  • Hotel has 23 suites
From$75
Average 3.0 /5 Guest Reviews Call BookMore Details
The Guild Current at the Banks
+1-888-469-4795
120 East Freedom Way, Cincinnati, OH 45202 ~2.29 miles south of 45221
  • Three Star Downtown hotel
  • Check-in: 3:00 PM
From$80
Average 3.0 /5 Reviews Call BookMore Details
Guild Cincinnati at the Banks - Cincinnati
+1-888-734-9421
121 East Freedom Way, Cincinnati, OH 45202 ~2.32 miles south of 45221
  • 3-star Downtown property
  • Gym is available on property
From$159
Very Good 4.0 /5 Recent Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks
+1-888-841-5292
135 Joe Nuxhall Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Affordable Downtown property
  • Check-in: 16:00
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Guild Radius : 44 West Freedom Way
+1-888-455-5160
44 West Freedom Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Midscale hotel
  • Check-in: 15:00
From$90
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati - Newport
+1-888-965-8297
420 Riverboat Rd., Newport, KY 41071 ~2.42 miles southeast of 45221
  • Low-priced Downtown property
  • Hotel has 6 floors
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG
+1-888-906-6358
109 Landmark Dr., Bellevue, KY 41073 ~2.65 miles southeast of 45221
  • Cheap Riverfront property
  • Hotel has 26 suites
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati in Newport
+1-888-749-6785
275 Columbia St., Newport, KY 41071 ~2.75 miles south of 45221
  • Midscale Riverfront property
  • Check in: 4:00pm
From$149
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter
+1-888-878-9982
10 West Rivercenter Blvd., Covington, KY 41011 ~2.80 miles south of 45221
  • Four-star Downtown property
  • 40 conference rooms in property
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter
+1-888-389-4485
10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • Mid-scale Downtown property
  • Fitness + Health Center
From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites Newport Cincinnati
+1-888-389-4121
201 West 4th St., Newport, KY 41071 ~2.86 miles south of 45221
  • Four star Riverfront hotel
  • Check in time: 4pm
From$125
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Cincinnati Riverfront An Ihg Hotel - Covington
+1-888-675-2083
600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Affordable Downtown hotel
  • 3 suites in property
From$88
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront
+1-800-716-8490
200 Crescent Ave., Covington, KY 41011 ~2.95 miles south of 45221
  • Mid-scale Riverfront property
  • Hotel has an eco-friendly policy See more
From$79
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington
+1-800-805-5223
500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Affordable Downtown hotel
  • Hotel has 9 floors
From$80
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Cincinnati Covington
+1-888-965-1860
650 West 3rd St., Covington, KY 41011 ~2.98 miles south of 45221
  • Low Cost Downtown hotel
  • Hotel has 4 floors
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront
+1-888-788-5576
668 West 5th St., Covington, KY 41011 ~3.12 miles south of 45221
  • Three Star Downtown property
  • Check-in time: 3:00 PM
From$79
Average 3.5 /5 Reviews Call BookMore Details
Hilton Garden Inn Cincinnati Midtown in Cincinnati
+1-888-897-9207
2145 Dana Ave., Cincinnati, OH 45207 ~3.19 miles east of 45221
  • Three Star Downtown hotel
  • Fitness center on property
From$120
Very Good 4.0 /5 Reviews Call BookMore Details
Hotel Covington Cincinnati Riverfront : 638 Madison Ave.
+1-888-311-4278
638 Madison Ave., Covington, KY 41011 ~3.24 miles south of 45221
  • 4-star Downtown property
  • Check-in time: 3:00 PM
From$149
Very Good 4.0 /5 Review Score Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood
+1-888-469-4795
3813 Edwards Rd., Cincinnati, OH 45209 ~4.02 miles east of 45221
  • 3 star Highway hotel
  • Check-in time: 4:00PM
From$100
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Six Acres Bed & Breakfast - Cincinnati
+1-888-734-9421
5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • Affordable property
From$20
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Cincinnati Oakley in Cincinnati
+1-888-841-5292
4609 a Factory Colony Ln, Cincinnati, OH 45209 ~4.96 miles east of 45221
  • Mid-scale property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites Cincinnati Oakley
+1-888-455-5160
4609 B Factory Colony Ln, Cincinnati, OH 45209 ~4.96 miles east of 45221
  • 3 star property
From$80
Average 3.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH in Cincinnati
+1-888-965-8297
4605 Factory Colony Lane, Cincinnati, OH 45209 ~5.01 miles east of 45221
  • Mid-scale property
  • Gym / Fitness Center Available
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area : 1937 Dixie Highway
+1-888-906-6358
1937 Dixie Highway, Fort Wright, KY 41011 ~5.33 miles south of 45221
  • Economy property
  • Hotel has 84 rooms
From$60
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites - Cincinnati
+1-888-749-6785
5410 Ridge Ave., Cincinnati, OH 45213 ~5.65 miles northeast of 45221
  • Two-star Downtown property
  • Hotel has 10 suites
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Cincinnati I-71
+1-888-878-9982
5300 Kennedy Ave., Cincinnati, OH 45213 ~5.66 miles east of 45221
  • Two star hotel
  • 2 floors in property

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, 21c Museum Hotel Cincinnati and Courtyard by Marriott Cincinnati-Covington are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel and Graduate by Hilton Cincinnati are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel, and Hampton Inn & Suites Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $96.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $125.76 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $166.58 per night. (based on HotelPlanner prices)

What are the best independent hotels near 45221?

21c Museum Hotel Cincinnati, voco The Clair Cincinnati Downtown, an IHG Hotel and Guild Cincinnati at the Banks are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Comfort Inn & Suites, Comfort Suites and Quality Inn & Suites Cincinnati Downtown are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 45221?

Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG, Holiday Inn Express & Suites Cincinnati Riverfront and Holiday Inn Cincinnati Riverfront An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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