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45221 Hotels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area : 2500 South Market St.
+1-888-389-4121
2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • Mid-scale Rural property
  • 34 suites in property
From$80
Average 3.0 /5 Reviews Call BookMore Details
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Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel
+1-888-675-2083
310 Straight St., Cincinnati, OH 45219 ~0.29 miles west of 45221
  • Expensive Suburban hotel
  • Check-in time: 3:00 PM
From$129
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati/Uptown-University Area
+1-800-716-8490
3024 Vine St., Cincinnati, OH 45219 ~0.47 miles northeast of 45221
  • 3-star Suburban hotel
  • Check in: 4:00 PM
From$110
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Graduate by Hilton Cincinnati
+1-800-805-5223
151 Goodman Dr., Cincinnati, OH 45219 ~0.62 miles northeast of 45221
  • Four-star Downtown hotel
  • Hotel has an eco-friendly policy Learn more
From$75
Very Good 4.0 /5 Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati - Cincinnati
+1-888-965-1860
2347 Reading Rd., Cincinnati, OH 45202 ~0.85 miles east of 45221
  • Two star Downtown property
  • 72 rooms in hotel
From$89
Average 3.0 /5 Recent Reviews Call BookMore Details
Springhill Suites Midtown Cincinnati - Cincinnati
+1-888-788-5576
610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • 3 star Downtown hotel
  • Hotel has 5 floors
From$80
Average 3.0 /5 Review Score Call BookMore Details
voco The Clair Cincinnati Downtown, an IHG Hotel - Cincinnati
+1-888-897-9207
701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 ~1.83 miles south of 45221
  • 3-star Downtown property
  • 6 floors in property
From$144
Very Good 4.0 /5 Read Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown
+1-888-311-4278
106 West 7th St., Cincinnati, OH 45202 ~1.84 miles south of 45221
  • Midscale Downtown hotel
  • Comp. Breakfast
From$100
Excellent 5.0 /5 Hotel Reviews Call BookMore Details
The Guild Downtown | Vine Street
+1-888-469-4795
642 Vine St., Cincinnati, OH 45202 ~1.86 miles south of 45221
  • 3-star Downtown property
  • Gym / Fitness Center Available
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Kinley Cincinnati Hotel
+1-888-734-9421
636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • 4 star Downtown property
  • Hotel has a green policy Learn more
From$149
Average 3.0 /5 Latest Reviews Call BookMore Details
Kinley Cincinnati Downtown - Cincinnati
+1-888-841-5292
636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • Four-star Downtown hotel
  • Hotel has an eco-friendly policy Learn more
From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
21c Museum Hotel Cincinnati : 609 Walnut St.
+1-888-455-5160
609 Walnut St., Cincinnati, OH 45202 ~1.88 miles south of 45221
  • 4-star Downtown hotel
  • Hotel has a green policy See policy
From$160
Very Good 4.5 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown - Cincinnati
+1-888-965-8297
617b Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Midscale Downtown hotel
  • Hotel has 6 floors
From$111
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati-Downtown
+1-888-906-6358
617 Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Mid-scale Downtown property
  • Check-in time: 3:00pm
From$91
Average 3.0 /5 Latest Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton - Cincinnati
+1-888-749-6785
601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • High end Downtown hotel
  • 146 rooms in hotel
From$95
Average 3.0 /5 Review Score Call BookMore Details
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Quality Inn & Suites Cincinnati Downtown - Cincinnati
+1-888-878-9982
800 West 8th St., Cincinnati, OH 45203 ~1.98 miles south of 45221
  • Two star Downtown property
  • 6 meeting rooms in property
From$46
Average 3.0 /5 Recent Reviews Call BookMore Details
Millennium Cincinnati : 150 West 5th St.
+1-888-389-4485
150 West 5th St., Cincinnati, OH 45202 ~1.98 miles south of 45221
  • Three Star Downtown hotel
  • Hotel has 32 floors
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza
+1-888-389-4121
35 West 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • Four-star Downtown property
  • Hotel has 29 floors
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Westin Cincinnati
+1-888-675-2083
21 East 5th St., Cincinnati, OH 45202 ~2.04 miles south of 45221
  • Affordable Downtown hotel
  • Hotel has a green policy See more
From$129
Average 3.0 /5 Guest Reviews Call BookMore Details
Hyatt Regency Cincinnati in Cincinnati
+1-800-716-8490
151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • High-end Downtown hotel
  • Fitness center on property
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps
+1-800-805-5223
506 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • High-end hotel
  • Free comp. breakfast
From$160
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown
+1-888-965-1860
6 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Mid-scale Downtown hotel
  • 13 floors in hotel
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel : 36 East 4th St.
+1-888-788-5576
36 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • 4-star Downtown property
  • 19 floors in property
From$139
Very Good 4.0 /5 Review Score Call BookMore Details
The Lytle Park Hotel Autograph Collection - Cincinnati
+1-888-897-9207
311 Pike St., Cincinnati, OH 45202 ~2.11 miles south of 45221
  • Luxury 5 star property
  • 5 floors in hotel
From$289
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites
+1-888-311-4278
130 West Mitchell Ave., Cincinnati, OH 45217 ~2.25 miles north of 45221
  • Midscale Downtown property
  • 3 floors in property
From$75
Average 3.0 /5 Reviews Call BookMore Details
The Guild Current at the Banks in Cincinnati
+1-888-469-4795
120 East Freedom Way, Cincinnati, OH 45202 ~2.29 miles south of 45221
  • Midscale Downtown hotel
  • Check in: 3:00 PM
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Guild Cincinnati at the Banks : 121 East Freedom Way
+1-888-734-9421
121 East Freedom Way, Cincinnati, OH 45202 ~2.32 miles south of 45221
  • 3 star Downtown property
  • 43 sleeping rooms in hotel
From$159
Very Good 4.0 /5 Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks - Cincinnati
+1-888-841-5292
135 Joe Nuxhall Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Three Star Downtown hotel
  • Access to gym on-site
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Guild Radius - Cincinnati
+1-888-455-5160
44 West Freedom Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • 3-star property
  • 5 rooms in property
From$90
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati - Newport
+1-888-965-8297
420 Riverboat Rd., Newport, KY 41071 ~2.42 miles southeast of 45221
  • Economy Downtown hotel
  • 6 floors in property
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG in Bellevue
+1-888-906-6358
109 Landmark Dr., Bellevue, KY 41073 ~2.65 miles southeast of 45221
  • 2-star Riverfront property
  • 73 rooms in hotel
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati
+1-888-749-6785
275 Columbia St., Newport, KY 41071 ~2.75 miles south of 45221
  • Midscale Riverfront hotel
  • 122 rooms in hotel
From$149
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter
+1-888-878-9982
10 West Rivercenter Blvd., Covington, KY 41011 ~2.80 miles south of 45221
  • High end Downtown hotel
  • 16 floors in hotel
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter
+1-888-389-4485
10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • 3 star Downtown hotel
  • Check-in time: 4:00 PM
From$109
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites Newport Cincinnati
+1-888-389-4121
201 West 4th St., Newport, KY 41071 ~2.86 miles south of 45221
  • High-end Riverfront hotel
  • Hotel has 133 suites
From$125
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Cincinnati Riverfront An Ihg Hotel - Covington
+1-888-675-2083
600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Mid-scale Downtown property
  • Hotel has 155 rooms
From$88
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront - Covington
+1-800-716-8490
200 Crescent Ave., Covington, KY 41011 ~2.95 miles south of 45221
  • 3-star Riverfront hotel
  • Hotel has an eco-friendly policy See more
From$79
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington : 500 West 3rd St.
+1-800-805-5223
500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • 3 star Downtown hotel
  • Check in: 3:00 PM
From$80
Very Good 4.5 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Cincinnati Covington : 650 West 3rd St.
+1-888-965-1860
650 West 3rd St., Covington, KY 41011 ~2.98 miles south of 45221
  • Cheap Downtown property
  • Check in time: 3:00pm
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront : 668 West 5th St.
+1-888-788-5576
668 West 5th St., Covington, KY 41011 ~3.12 miles south of 45221
  • Mid-scale Downtown hotel
  • Check-in time: 3:00 PM
From$79
Average 3.5 /5 Reviews Call BookMore Details
Hilton Garden Inn Cincinnati Midtown
+1-888-897-9207
2145 Dana Ave., Cincinnati, OH 45207 ~3.19 miles east of 45221
  • Midscale Downtown property
  • Hotel has 120 rooms
From$120
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hotel Covington Cincinnati Riverfront in Covington
+1-888-311-4278
638 Madison Ave., Covington, KY 41011 ~3.24 miles south of 45221
  • Expensive Downtown property
  • 4 meeting rooms in property
From$149
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood
+1-888-469-4795
3813 Edwards Rd., Cincinnati, OH 45209 ~4.02 miles east of 45221
  • Three Star Highway hotel
  • 4 meeting rooms in hotel
From$100
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Six Acres Bed & Breakfast
+1-888-734-9421
5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • Midscale property
From$20
Very Good 4.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Cincinnati Oakley in Cincinnati
+1-888-841-5292
4609 a Factory Colony Ln, Cincinnati, OH 45209 ~4.96 miles east of 45221
  • Affordable hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites Cincinnati Oakley
+1-888-455-5160
4609 B Factory Colony Ln, Cincinnati, OH 45209 ~4.96 miles east of 45221
  • Affordable hotel
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH
+1-888-965-8297
4605 Factory Colony Lane, Cincinnati, OH 45209 ~5.01 miles east of 45221
  • Midscale property
  • Check-in time: 15:00
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area
+1-888-906-6358
1937 Dixie Highway, Fort Wright, KY 41011 ~5.33 miles south of 45221
  • Low priced hotel
  • 84 sleeping rooms in hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites in Cincinnati
+1-888-749-6785
5410 Ridge Ave., Cincinnati, OH 45213 ~5.65 miles northeast of 45221
  • Two-star Downtown hotel
  • 106 rooms in hotel
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Cincinnati I-71 - Cincinnati
+1-888-878-9982
5300 Kennedy Ave., Cincinnati, OH 45213 ~5.66 miles east of 45221
  • Two-star property
  • 75 sleeping rooms in hotel
From$60
Poor 2.0 /5 Reviews Call BookMore Details

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, 21c Museum Hotel Cincinnati and Courtyard by Marriott Cincinnati-Covington are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel and Graduate by Hilton Cincinnati are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel, and Hampton Inn & Suites Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $96.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $125.76 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $166.58 per night. (based on HotelPlanner prices)

What are the best independent hotels near 45221?

21c Museum Hotel Cincinnati, voco The Clair Cincinnati Downtown, an IHG Hotel and Guild Cincinnati at the Banks are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Comfort Inn & Suites, Comfort Suites and Quality Inn & Suites Cincinnati Downtown are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 45221?

Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG, Holiday Inn Express & Suites Cincinnati Riverfront and Holiday Inn Cincinnati Riverfront An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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