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45221 Hotels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area
+1-888-389-4121
2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • Affordable Rural hotel
  • Free complimentary breakfast
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel
+1-888-675-2083
310 Straight St., Cincinnati, OH 45219 ~0.29 miles west of 45221
  • Expensive Suburban hotel
  • Fitness + Health Center
From$129
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati/Uptown-University Area
+1-800-716-8490
3024 Vine St., Cincinnati, OH 45219 ~0.47 miles northeast of 45221
  • Mid-scale Suburban hotel
  • Check in: 4:00 PM
From$110
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Graduate by Hilton Cincinnati - Cincinnati
+1-800-805-5223
151 Goodman Dr., Cincinnati, OH 45219 ~0.62 miles northeast of 45221
  • 4-star Downtown hotel
  • 11 suites in property
From$75
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati : 2347 Reading Rd.
+1-888-965-1860
2347 Reading Rd., Cincinnati, OH 45202 ~0.85 miles east of 45221
  • Two-star Downtown hotel
  • 72 suites in hotel
From$89
Average 3.0 /5 Hotel Reviews Call BookMore Details
Springhill Suites Midtown Cincinnati
+1-888-788-5576
610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • 3-star Downtown property
  • Check-in: 3:00 pm
From$80
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Hotel & Suites Cincinnati Downtown, an IHG Hotel in Cincinnati
+1-888-897-9207
701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 ~1.83 miles south of 45221
  • Midscale Downtown hotel
  • Check in time: 3:00pm
From$144
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown in Cincinnati
+1-888-311-4278
106 West 7th St., Cincinnati, OH 45202 ~1.84 miles south of 45221
  • Midscale Downtown property
  • Check in: 3:00PM
From$100
Excellent 5.0 /5 Read Reviews Call BookMore Details
The Guild Downtown | Vine Street
+1-888-469-4795
642 Vine St., Cincinnati, OH 45202 ~1.86 miles south of 45221
  • Mid-scale Downtown hotel
  • Hotel has 48 rooms
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Kinley Cincinnati Hotel in Cincinnati
+1-888-734-9421
636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • Four star Downtown property
  • 94 rooms in property
From$149
Average 3.0 /5 Reviews Call BookMore Details
Kinley Cincinnati Downtown : 37 West 7th St.
+1-888-841-5292
37 West 7th St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • Three Star property
  • Access to gym on-site
From$90
Very Good 4.0 /5 Read Reviews Call BookMore Details
21c Museum Hotel Cincinnati
+1-888-455-5160
609 Walnut St., Cincinnati, OH 45202 ~1.88 miles south of 45221
  • High end Downtown hotel
  • Hotel has a green policy Learn more
From$160
Very Good 4.5 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown
+1-888-965-8297
617b Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Mid-scale Downtown property
  • Fitness center on property
From$111
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati-Downtown in Cincinnati
+1-888-906-6358
617 Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Three Star Downtown property
  • 144 rooms in property
From$91
Average 3.0 /5 Read Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton : 601 Vine St.
+1-888-749-6785
601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • 4 star Downtown hotel
  • Gym / Fitness Center Available
From$95
Average 3.0 /5 Recent Reviews Call BookMore Details
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Quality Inn & Suites Cincinnati Downtown - Cincinnati
+1-888-878-9982
800 West 8th St., Cincinnati, OH 45203 ~1.98 miles south of 45221
  • Economy Downtown hotel
  • Complimentary breakfast is offered
From$46
Average 3.0 /5 Latest Reviews Call BookMore Details
Millennium Cincinnati
+1-888-389-4485
150 West 5th St., Cincinnati, OH 45202 ~1.98 miles south of 45221
  • Three Star Downtown hotel
  • Hotel has 32 floors
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza in Cincinnati
+1-888-389-4121
35 West 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • Four star Downtown property
  • Hotel has an eco-friendly policy Learn more
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Westin Cincinnati in Cincinnati
+1-888-675-2083
21 East 5th St., Cincinnati, OH 45202 ~2.04 miles south of 45221
  • 3-star Downtown hotel
  • 9 suites in hotel
From$129
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Regency Cincinnati in Cincinnati
+1-800-716-8490
151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • Four star Downtown hotel
  • Gym / Fitness Center Available
From$99
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps in Cincinnati
+1-800-805-5223
506 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Four-star hotel
  • Gym is available on property
From$160
Very Good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown - Cincinnati
+1-888-965-1860
6 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Three Star Downtown property
  • 6 suites in property
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel
+1-888-788-5576
36 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Four star Downtown property
  • 19 floors in hotel
From$139
Very Good 4.0 /5 Read Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection - Cincinnati
+1-888-897-9207
311 Pike St., Cincinnati, OH 45202 ~2.11 miles south of 45221
  • Luxury 5-star hotel
  • Check in: 4PM
From$289
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites in Cincinnati
+1-888-311-4278
130 West Mitchell Ave., Cincinnati, OH 45217 ~2.25 miles north of 45221
  • 3-star Downtown property
  • Hotel has 54 rooms
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
The Guild Current at the Banks
+1-888-469-4795
120 East Freedom Way, Cincinnati, OH 45202 ~2.29 miles south of 45221
  • Three Star Downtown hotel
  • 5 floors in hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Guild Cincinnati at the Banks : 121 East Freedom Way
+1-888-734-9421
121 East Freedom Way, Cincinnati, OH 45202 ~2.32 miles south of 45221
  • Three Star Downtown property
  • 43 rooms in property
From$159
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks - Cincinnati
+1-888-841-5292
135 Joe Nuxhall Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Affordable Downtown property
  • Fitness center on property
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Guild Radius - Cincinnati
+1-888-455-5160
44 West Freedom Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Affordable hotel
  • 5 rooms in property
From$90
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati - Newport
+1-888-965-8297
420 Riverboat Rd., Newport, KY 41071 ~2.42 miles southeast of 45221
  • Economical Downtown property
  • 124 rooms in property
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG : 109 Landmark Dr.
+1-888-906-6358
109 Landmark Dr., Bellevue, KY 41073 ~2.65 miles southeast of 45221
  • Low Cost Riverfront property
  • Gym / Fitness Center Available
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati - Newport
+1-888-749-6785
275 Columbia St., Newport, KY 41071 ~2.75 miles south of 45221
  • 3 star Riverfront property
  • Free comp. breakfast
From$149
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter - Covington
+1-888-878-9982
10 West Rivercenter Blvd., Covington, KY 41011 ~2.80 miles south of 45221
  • High end Downtown hotel
  • 4 suites in hotel
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter : 10 East Rivercenter Blvd.
+1-888-389-4485
10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • Midscale Downtown property
  • 10 conference rooms in property
From$109
Very Good 4.0 /5 Read Reviews Call BookMore Details
Homewood Suites Newport Cincinnati - Newport
+1-888-389-4121
201 West 4th St., Newport, KY 41071 ~2.86 miles south of 45221
  • Four-star Riverfront property
  • Hotel has 133 suites
From$125
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Cincinnati Riverfront An Ihg Hotel - Covington
+1-888-675-2083
600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • 3-star Downtown hotel
  • 155 sleeping rooms in hotel
From$88
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront in Covington
+1-800-716-8490
200 Crescent Ave., Covington, KY 41011 ~2.95 miles south of 45221
  • Affordable Riverfront hotel
  • 127 rooms in property
From$79
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington - Covington
+1-800-805-5223
500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Three Star Downtown property
  • Check-in time: 3:00 PM
From$80
Very Good 4.5 /5 Reviews Call BookMore Details
Extended Stay America Suites Cincinnati Covington
+1-888-965-1860
650 West 3rd St., Covington, KY 41011 ~2.98 miles south of 45221
  • Low priced Downtown hotel
  • Hotel has 105 rooms
From$79
Average 3.0 /5 Latest Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront : 668 West 5th St.
+1-888-788-5576
668 West 5th St., Covington, KY 41011 ~3.12 miles south of 45221
  • Midscale Downtown hotel
  • Hotel has 220 rooms
From$79
Average 3.5 /5 Hotel Reviews Call BookMore Details
Hilton Garden Inn Cincinnati Midtown
+1-888-897-9207
2145 Dana Ave., Cincinnati, OH 45207 ~3.19 miles east of 45221
  • Midscale Downtown hotel
  • 4 meeting rooms in property
From$120
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hotel Covington Cincinnati Riverfront
+1-888-311-4278
638 Madison Ave., Covington, KY 41011 ~3.24 miles south of 45221
  • Four star Downtown hotel
  • Check-in time: 3:00 PM
From$149
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood : 3813 Edwards Rd.
+1-888-469-4795
3813 Edwards Rd., Cincinnati, OH 45209 ~4.02 miles east of 45221
  • Affordable Highway hotel
  • 4 floors in property
From$100
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Six Acres Bed & Breakfast in Cincinnati
+1-888-734-9421
5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • Affordable hotel
From$20
Very Good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH in Cincinnati
+1-888-841-5292
4605 Factory Colony Lane, Cincinnati, OH 45209 ~5.01 miles east of 45221
  • Affordable property
  • Check-in time: 15:00
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area in Fort Wright
+1-888-455-5160
1937 Dixie Highway, Fort Wright, KY 41011 ~5.33 miles south of 45221
  • Two-star hotel
  • 84 sleeping rooms in hotel
From$60
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites
+1-888-965-8297
5410 Ridge Ave., Cincinnati, OH 45213 ~5.65 miles northeast of 45221
  • 2 star Downtown property
  • Free complimentary breakfast
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Cincinnati I-71 : 5300 Kennedy Ave.
+1-888-906-6358
5300 Kennedy Ave., Cincinnati, OH 45213 ~5.66 miles east of 45221
  • Low priced property
  • Hotel has 75 rooms
Execustay at Centennial Station
+1-888-749-6785
4209 Erie Ave., Cincinnati, OH 45227 ~6.26 miles east of 45221
  • 3 star Suburban hotel
  • 307 rooms in property
From$90
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Ne Redbank Road Oh
+1-888-878-9982
5311 Hetzell St., Cincinnati, OH 45227 ~6.31 miles east of 45221
  • 3 star Suburban property
  • 38 suites in property
From$80
Average 3.0 /5 Latest Reviews Call BookMore Details

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, 21c Museum Hotel Cincinnati and Courtyard by Marriott Cincinnati-Covington are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel and Graduate by Hilton Cincinnati are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel, and Hampton Inn & Suites Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $96.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $125.76 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $166.58 per night. (based on HotelPlanner prices)

What are the best independent hotels near 45221?

21c Museum Hotel Cincinnati, Kinley Cincinnati Downtown and Guild Cincinnati at the Banks are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Comfort Inn & Suites, Comfort Suites and Quality Inn & Suites Cincinnati Downtown are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 45221?

Holiday Inn Hotel & Suites Cincinnati Downtown, an IHG Hotel, Holiday Inn Express Hotel & Suites Cincinnati Se Newport, an IHG and Holiday Inn Express & Suites Cincinnati Riverfront are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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