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45221 Hotels & Accommodations

Fairfield Inn & Suites Cincinnati Uptown/University Area
+1-888-389-4121
2500 South Market St., Cincinnati, OH 45219 ~0.18 miles south of 45221
  • Mid-scale Rural property
  • 34 suites in hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
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Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel - Cincinnati
+1-888-675-2083
310 Straight St., Cincinnati, OH 45219 ~0.29 miles west of 45221
  • 4 star Suburban property
  • 7 floors in property
From$129
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Cincinnati/Uptown-University Area
+1-800-716-8490
3024 Vine St., Cincinnati, OH 45219 ~0.47 miles northeast of 45221
  • Mid-scale Suburban hotel
  • Fitness / Gym is on-site
From$110
Very Good 4.0 /5 Reviews Call BookMore Details
Graduate by Hilton Cincinnati
+1-800-805-5223
151 Goodman Dr., Cincinnati, OH 45219 ~0.62 miles northeast of 45221
  • High end Downtown property
  • 8 floors in property
From$75
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Suites / Mainstay Suites Cincinnati
+1-888-965-1860
2347 Reading Rd., Cincinnati, OH 45202 ~0.85 miles east of 45221
  • Two-star Downtown hotel
  • 72 rooms in hotel
From$89
Average 3.0 /5 Reviews Call BookMore Details
Springhill Suites Midtown Cincinnati in Cincinnati
+1-888-788-5576
610 Eden Park Dr., Cincinnati, OH 45202 ~1.24 miles southeast of 45221
  • 3 star Downtown property
  • 122 sleeping rooms in hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
voco The Clair Cincinnati Downtown by IHG : 701 Broadway St. Cincinnati Oh 45202
+1-888-897-9207
701 Broadway St. Cincinnati Oh 45202, Cincinnati, OH 45202 ~1.83 miles south of 45221
  • Affordable Downtown property
  • Check in time: 3:00pm
From$144
Very Good 4.0 /5 Reviews Call BookMore Details
Towneplace Suites Cincinnati Downtown
+1-888-311-4278
106 West 7th St., Cincinnati, OH 45202 ~1.84 miles south of 45221
  • 3 star Downtown hotel
  • Hotel has 110 rooms
From$100
Excellent 5.0 /5 Reviews Call BookMore Details
The Guild Downtown | Vine Street : 642 Vine St.
+1-888-469-4795
642 Vine St., Cincinnati, OH 45202 ~1.86 miles south of 45221
  • Three Star Downtown property
  • 5 floors in hotel
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Kinley Cincinnati Downtown a Tribute Portfolio Hotel
+1-888-734-9421
636 Race St., Cincinnati, OH 45202 ~1.87 miles south of 45221
  • Four star Downtown hotel
  • Hotel has 9 floors
From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
21c Museum Hotel Cincinnati : 609 Walnut St.
+1-888-841-5292
609 Walnut St., Cincinnati, OH 45202 ~1.88 miles south of 45221
  • Four-star Downtown property
  • Hotel has 20 suites
From$160
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Downtown
+1-888-455-5160
617b Vine St., Cincinnati, OH 45202 ~1.89 miles south of 45221
  • Midscale Downtown hotel
  • 6 floors in hotel
From$111
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn
+1-888-965-8297
617 Vine St., Cincinnati, OH 45202 ~1.90 miles south of 45221
  • 3 star Downtown hotel
  • Check in time: 3:00pm
From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
The Cincinnatian Hotel Curio Collection by Hilton : 601 Vine St.
+1-888-906-6358
601 Vine St., Cincinnati, OH 45209 ~1.92 miles south of 45221
  • Expensive Downtown hotel
  • Check in: 3pm
From$95
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites Cincinnati Downtown : 800 West 8th St.
+1-888-749-6785
800 West 8th St., Cincinnati, OH 45203 ~1.98 miles south of 45221
  • Inexpensive Downtown property
  • Free comp. breakfast
From$70
Average 3.0 /5 Review Score Call BookMore Details
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Millennium Cincinnati
+1-888-878-9982
150 West 5th St., Cincinnati, OH 45202 ~1.98 miles south of 45221
  • Mid-scale Downtown property
  • Airport shuttle available
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Hilton Cincinnati Netherland Plaza in Cincinnati
+1-888-389-4485
35 West 5th St., Cincinnati, OH 45202 ~2.03 miles south of 45221
  • High-end Downtown property
  • Gym / Fitness Center Available
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Westin Cincinnati
+1-888-389-4121
21 East 5th St., Cincinnati, OH 45202 ~2.04 miles south of 45221
  • Affordable Downtown property
  • Check in time: 4pm
From$129
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hyatt Regency Cincinnati
+1-888-675-2083
151 West 5th St., Cincinnati, OH 45202 ~2.07 miles south of 45221
  • Four star Downtown property
  • 13 suites in hotel
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Residence Inn by Marriott Cincinnati Downtown/The Phelps in Cincinnati
+1-800-716-8490
506 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • High end hotel
  • Fitness + Health Center
From$160
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Cincinnati Downtown
+1-800-805-5223
6 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • 3-star Downtown property
  • Hotel has 13 floors
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Renaissance Cincinnati Downtown Hotel
+1-888-965-1860
36 East 4th St., Cincinnati, OH 45202 ~2.08 miles south of 45221
  • Four-star Downtown hotel
  • 281 sleeping rooms in hotel
From$139
Very Good 4.0 /5 Latest Reviews Call BookMore Details
The Lytle Park Hotel Autograph Collection - Cincinnati
+1-888-788-5576
311 Pike St., Cincinnati, OH 45202 ~2.11 miles south of 45221
  • Luxury 5 star hotel
  • Check-in time: 4PM
From$289
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites
+1-888-897-9207
130 West Mitchell Ave., Cincinnati, OH 45217 ~2.25 miles north of 45221
  • Three Star Downtown hotel
  • Hotel has 54 rooms
From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
The Guild Current at the Banks in Cincinnati
+1-888-311-4278
120 East Freedom Way, Cincinnati, OH 45202 ~2.29 miles south of 45221
  • 3 star Downtown property
  • 53 suites in hotel
From$80
Average 3.0 /5 Review Score Call BookMore Details
Guild Cincinnati at the Banks : 121 East Freedom Way
+1-888-469-4795
121 East Freedom Way, Cincinnati, OH 45202 ~2.32 miles south of 45221
  • 3 star Downtown hotel
  • Hotel has 43 rooms
From$159
Very Good 4.0 /5 Latest Reviews Call BookMore Details
AC Hotel by Marriott Cincinnati at the Banks
+1-888-734-9421
135 Joe Nuxhall Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Affordable Downtown property
  • Fitness center on property
From$80
Very Good 4.0 /5 Reviews Call BookMore Details
Guild Radius : 44 West Freedom Way
+1-888-841-5292
44 West Freedom Way, Cincinnati, OH 45202 ~2.34 miles south of 45221
  • Mid-scale hotel
  • 5 rooms in hotel
From$90
Average 3.0 /5 Review Score Call BookMore Details
Fairfield by Marriott Inn & Suites Newport Cincinnati
+1-888-455-5160
420 Riverboat Rd., Newport, KY 41071 ~2.42 miles southeast of 45221
  • Cheap Downtown hotel
  • 124 suites in hotel
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG
+1-888-965-8297
109 Landmark Dr., Bellevue, KY 41073 ~2.65 miles southeast of 45221
  • Cheap Riverfront property
  • Hotel has an eco-friendly policy Learn more
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Newport/Cincinnati
+1-888-906-6358
275 Columbia St., Newport, KY 41071 ~2.75 miles south of 45221
  • 3 star Riverfront hotel
  • 2 meeting rooms in hotel
From$149
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Cincinnati Marriott at Rivercenter : 10 West Rivercenter Blvd.
+1-888-749-6785
10 West Rivercenter Blvd., Covington, KY 41011 ~2.80 miles south of 45221
  • High end Downtown property
  • 16 floors in hotel
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Embassy Suites by Hilton Cincinnati Rivercenter - Covington
+1-888-878-9982
10 East Rivercenter Blvd., Covington, KY 41011 ~2.82 miles south of 45221
  • Mid-scale Downtown property
  • Check-in: 4:00 PM
From$109
Very Good 4.0 /5 Review Score Call BookMore Details
Homewood Suites Newport Cincinnati : 201 West 4th St.
+1-888-389-4485
201 West 4th St., Newport, KY 41071 ~2.86 miles south of 45221
  • Four-star Riverfront property
  • Hotel has 5 floors
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Cincinnati Riverfront An Ihg Hotel : 600 West 3rd St.
+1-888-389-4121
600 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Three Star Downtown hotel
  • 3 meeting rooms in hotel
From$88
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Cincinnati Riverfront in Covington
+1-888-675-2083
200 Crescent Ave., Covington, KY 41011 ~2.95 miles south of 45221
  • Affordable Riverfront hotel
  • 20 suites in property
From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Cincinnati-Covington
+1-800-716-8490
500 West 3rd St., Covington, KY 41011 ~2.95 miles south of 45221
  • Three Star Downtown hotel
  • Gym / Fitness Center Available
From$80
Very Good 4.5 /5 Reviews Call BookMore Details
Extended Stay America Suites Cincinnati Covington : 650 West 3rd St.
+1-800-805-5223
650 West 3rd St., Covington, KY 41011 ~2.98 miles south of 45221
  • Economy Downtown property
  • Check-in: 3:00pm
From$79
Average 3.0 /5 Hotel Reviews Call BookMore Details
Radisson Hotel Cincinnati Riverfront
+1-888-965-1860
668 West 5th St., Covington, KY 41011 ~3.12 miles south of 45221
  • Midscale Downtown property
  • 4 suites in property
From$79
Average 3.5 /5 Reviews Call BookMore Details
Hilton Garden Inn Cincinnati Midtown in Cincinnati
+1-888-788-5576
2145 Dana Ave., Cincinnati, OH 45207 ~3.19 miles east of 45221
  • Three Star Downtown property
  • Hotel has 4 meeting rooms
From$120
Very Good 4.0 /5 Review Score Call BookMore Details
Hotel Covington Cincinnati Riverfront
+1-888-897-9207
638 Madison Ave., Covington, KY 41011 ~3.24 miles south of 45221
  • Four star Downtown hotel
  • Hotel has 7 floors
From$149
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Cincinnati Midtown/Rookwood : 3813 Edwards Rd.
+1-888-311-4278
3813 Edwards Rd., Cincinnati, OH 45209 ~4.02 miles east of 45221
  • Midscale Highway property
  • Hotel has 4 floors
From$100
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Six Acres Bed & Breakfast - Cincinnati
+1-888-469-4795
5350 Hamilton Ave., Cincinnati, OH 45224 ~4.26 miles north of 45221
  • Midscale hotel
From$20
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Cincinnati Oakley
+1-888-734-9421
4609 a Factory Colony Ln, Cincinnati, OH 45209 ~4.96 miles east of 45221
  • 3-star Suburban property
  • 5 floors in hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites Cincinnati Oakley : 4609 B Factory Colony Ln
+1-888-841-5292
4609 B Factory Colony Ln, Cincinnati, OH 45209 ~4.96 miles east of 45221
  • Mid-scale Suburban property
  • Hotel has 5 floors
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Cincinnati-Midtown, OH - Cincinnati
+1-888-455-5160
4605 Factory Colony Lane, Cincinnati, OH 45209 ~5.01 miles east of 45221
  • 3 star hotel
  • 108 rooms in hotel
From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Days Inn by Wyndham Fort Wright Cincinnati Area - Fort Wright
+1-888-965-8297
1937 Dixie Highway, Fort Wright, KY 41011 ~5.33 miles south of 45221
  • Economy hotel
  • Hotel has 84 rooms
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites : 5410 Ridge Ave.
+1-888-906-6358
5410 Ridge Ave., Cincinnati, OH 45213 ~5.65 miles northeast of 45221
  • Cheap Downtown hotel
  • Free breakfast available
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Cincinnati I-71 : 5300 Kennedy Ave.
+1-888-749-6785
5300 Kennedy Ave., Cincinnati, OH 45213 ~5.66 miles east of 45221
  • Cheap hotel
  • 2 floors in hotel
Execustay at Centennial Station
+1-888-878-9982
4209 Erie Ave., Cincinnati, OH 45227 ~6.26 miles east of 45221
  • Three Star Suburban hotel
  • 307 rooms in property
From$90
Average 3.0 /5 Hotel Reviews Call BookMore Details

Next: Show All Available 45221 Hotels with Pricing

Bar Chart: Upcoming 20 Days of 45221 Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Cincinnati, OH discounts available. The chart reflects the cheapest Cincinnati hotel for each day and each star rating category.

FAQs about hotels near 45221

What are the best rated hotels near 45221?

Towneplace Suites Cincinnati Downtown, 21c Museum Hotel Cincinnati and Courtyard by Marriott Cincinnati-Covington are the best rated hotels based on customer reviews in the last 365 days.

What are the 4-5 star hotels near 45221?

The Lytle Park Hotel Autograph Collection, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel and Graduate by Hilton Cincinnati are the top 3 luxury hotels near 45221.

What hotels are closest to the area of 45221?

Fairfield Inn & Suites Cincinnati Uptown, Hotel Celare Cincinnati Midtown a Tribute Portfolio Hotel, and Hampton Inn & Suites Cincinnati are the properties closest to 45221.

How much does a cheap hotel near 45221 cost per night?

In the last year, a 2 star hotel near 45221 can be as cheap as $96.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 45221 cost per night?

In the last year, the average 3 star hotel near 45221 has been $125.76 per night. (based on HotelPlanner prices)

How much does a 4-5 star hotel near 45221 cost?

In the last year, the average 4 star hotel near 45221 has been $166.58 per night. (based on HotelPlanner prices)

What are the best independent hotels near 45221?

21c Museum Hotel Cincinnati, voco The Clair Cincinnati Downtown by IHG and Guild Cincinnati at the Banks are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 45221?

Towneplace Suites Cincinnati Downtown, Courtyard by Marriott Cincinnati-Covington and Residence Inn by Marriott Cincinnati Downtown are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 45221?

Comfort Inn & Suites, Comfort Suites and Quality Inn & Suites Cincinnati Downtown are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 45221?

Holiday Inn Express Hotel & Suites Cincinnati Se Newport by IHG, Holiday Inn Express & Suites Cincinnati Riverfront and Holiday Inn Cincinnati Riverfront An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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