Hotels in 14221 - Buffalo NY

Only hotels in 14221 zip code are listed below. Search for cheap and discount hotel rates in Buffalo, NY for your upcoming leisure or conference / group travel. We list the best 14221 hotels and motels so you can review the Buffalo hotel list below to find the perfect lodging. Hotels in Erie county and area code 716 are also listed.

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14221 Hotels/Accommodations

La Quinta Inn by Wyndham Buffalo Airport : 6619 Transit Rd.
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
6619 Transit Rd., Williamsville, NY 14221
  • Cheap Airport hotel
  • Check in: 03:00 PM
More Photos Exterior of La Quinta Inn by Wyndham Buffalo Airport
From$79
Average 3.0 /5 Read Reviews Call BookMore Details
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Hawthorn Suites by Wyndham Williamsville Buffalo Airport
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
8005 Sheridan Dr., Williamsville, IN 14221
  • 3 star Airport property
  • Shuttle from airport available
More Photos Image of Hawthorn Suites by Wyndham Williamsville Buffalo Airport
From$80
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Springhill Suites Buffalo Airport
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
6647 Transit Rd., Buffalo, NY 14221
  • Three Star Suburban hotel
  • Hotel has 108 rooms
More Photos Exterior of Springhill Suites Buffalo Airport
From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Fairbridge Inn Express Buffalo Airport Williamsville - Williamsville
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
7200 Transit Rd., Williamsville, NY 14221
  • 2 star Airport property
  • 65 rooms in property
More Photos Photo of Fairbridge Inn Express Buffalo Airport Williamsville
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Buffalo-Williamsville - Williamsville
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
5455 Main St., Williamsville, NY 14221
  • Midscale Suburban property
  • Gym / Fitness Center Available
More Photos Exterior of Hampton Inn Buffalo-Williamsville
From$95
Very Good 4.0 /5 Guest Reviews Call BookMore Details
The Mosey Hotel a Tapestry Collection by Hilton
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
5195 Main St., Buffalo, NY 14221
  • 4 star Suburban property
  • Check in: 3:00 pm
More Photos Exterior of The Mosey Hotel a Tapestry Collection by Hilton
From$69
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Tru by Hilton Williamsville Buffalo Airport in Williamsville
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
48 Freeman Rd. Building A, Williamsville, NY 14221
  • Three Star Airport hotel
  • Airport shuttle available
More Photos Image of Tru by Hilton Williamsville Buffalo Airport
From$75
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 Buffalo Ny Airport Williamsville in Buffalo
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
52 Freeman Rd., Buffalo, NY 14221
  • 2 star Airport hotel
  • Check in time: 15:00
More Photos Photo of Motel 6 Buffalo Ny Airport Williamsville
From$60
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Best Western Buffalo Inn & Suites : 50 Freeman Rd.
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
50 Freeman Rd., Buffalo, NY 14221
  • 3-star Airport property
  • 71 sleeping rooms in hotel
More Photos Exterior of Best Western Buffalo Inn & Suites
From$73
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Garden Place Hotel
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
6615 Transit Rd., Williamsville, NY 14221
  • Mid-scale Airport property
  • 23 suites in hotel
More Photos Photo of Garden Place Hotel
From$81
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Courtyard by Marriott Buffalo Amherst / University
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
4100 Sheridan Dr., Buffalo, NY 14221
  • Three Star Suburban hotel
  • 7 suites in property
More Photos Image of Courtyard by Marriott Buffalo Amherst / University
From$119
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Residence Inn Buffalo Amherst
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
100 Maple Rd., Amherst, NY 14221
  • Three Star Suburban hotel
  • Has environment-friendly policy Read more
More Photos Image of Residence Inn Buffalo Amherst
From$79
Average 3.0 /5 Review Score Call BookMore Details
Hampton Inn Amherst / Buffalo
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1601 Amherst Manor Dr., Buffalo, NY 14221
  • Affordable Suburban hotel
  • Hotel has 107 rooms
More Photos Exterior of Hampton Inn Amherst / Buffalo
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
More Homes & Apts at Booking.com

Book online or call +1-800-219-2797

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Buffalo Marriott Niagara
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1340 Millersport Highway, Amherst, NY 14221
  • High end Suburban hotel
  • 17 conference rooms in property
More Photos Image of Buffalo Marriott Niagara
From$125
Average 3.0 /5 Recent Reviews Call BookMore Details
Hyatt Place Buffalo/Amherst
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
5020 Main St., Amherst, NY 14226 ~2.50 miles southwest of 14221
  • 3-star Suburban hotel
  • 6 floors in hotel
More Photos Image of Hyatt Place Buffalo/Amherst
From$95
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
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Jazzboline : 5010 Main St.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
5010 Main St., Amherst, NY 14226 ~2.68 miles southwest of 14221
  • 4 star property
More Photos hotel room
From$75
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Red Roof Inn Buffalo - Niagara Airport
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
146 Maple Dr., Bowmansville, NY 14026 ~2.69 miles southeast of 14221
  • Low Cost Airport hotel
  • Check in time: 12:00 PM
More Photos Photo of Red Roof Inn Buffalo - Niagara Airport
From$82
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Reikart House, Buffalo, a Tribute Portfolio Hotel in Amherst
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
5000 Main St., Amherst, NY 14226 ~2.71 miles southwest of 14221
  • High-end Suburban property
  • Hotel has 3 floors
More Photos Photo of Reikart House, Buffalo, a Tribute Portfolio Hotel
From$129
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Sleep Inn Buffalo Airport in Cheektowaga
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
100 Holtz Dr., Cheektowaga, NY 14225 ~3.01 miles south of 14221
  • Economical Airport property
  • 86 rooms in property
More Photos Photo of Sleep Inn Buffalo Airport
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Inn at Buffalo Airport : 4630 Genesee St.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4630 Genesee St., Cheektowaga, NY 14225 ~3.14 miles south of 14221
  • 2 star Airport hotel
  • Hotel has 4 floors
More Photos Photo of Inn at Buffalo Airport
From$60
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Buffalo Airport Hotel
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
4600 Genesee St., Cheektowaga, NY 14225 ~3.15 miles south of 14221
  • 3 star Airport property
  • Shuttle to airport available
More Photos Exterior of Buffalo Airport Hotel
From$49
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Buffalo Airport
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
4345 Genesee St., Buffalo, NY 14225 ~3.33 miles south of 14221
  • Mid-scale Suburban property
  • Comp. Breakfast
More Photos Photo of Comfort Inn & Suites Buffalo Airport
From$99
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Fairfield Inn & Suites by Marriott Buffalo Airport : 4271 Genesee St.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
4271 Genesee St., Buffalo, NY 14225 ~3.34 miles south of 14221
  • Three Star Airport property
  • Hotel has 140 rooms
More Photos Photo of Fairfield Inn & Suites by Marriott Buffalo Airport
From$107
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard Buffalo Airport - Cheektowaga
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
4243 Genesee St., Cheektowaga, NY 14225 ~3.40 miles south of 14221
  • 3 star Airport property
  • 5 floors in hotel
More Photos Exterior of Courtyard Buffalo Airport
From$97
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Comfort Inn University in Amherst
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1 Flint Rd., Amherst, NY 14226 ~3.42 miles west of 14221
  • 2-star Suburban hotel
  • Check in time: 3pm
More Photos Exterior of Comfort Inn University
From$55
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn Buffalo Airport : 4201 Genesee St.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
4201 Genesee St., Buffalo, NY 14225 ~3.46 miles south of 14221
  • 3 star Airport hotel
  • 158 rooms in property
More Photos Exterior of Hilton Garden Inn Buffalo Airport
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
DoubleTree by Hilton Hotel Buffalo - Amherst - Amherst
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
10 Flint Rd., Amherst, NY 14226 ~3.46 miles west of 14221
  • Four-star Suburban property
  • Fitness center on property
More Photos Photo of DoubleTree by Hilton Hotel Buffalo - Amherst
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn PLUS+ University at Buffalo - Amherst
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
42 Flint Rd., Amherst, NY 14226 ~3.47 miles west of 14221
  • Low priced Suburban property
  • Check-in: 3:00 PM
More Photos Image of Red Roof Inn PLUS+ University at Buffalo - Amherst
From$52
Poor 2.0 /5 Review Score Call BookMore Details
Towneplace Suites Buffalo Airport - Buffalo
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
4265 Genesee St., Buffalo, NY 14225 ~3.48 miles south of 14221
  • 3-star Airport property
  • Airport shuttle provided
More Photos Exterior of Towneplace Suites Buffalo Airport
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Airport
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
4217 Genesee St., Buffalo, NY 14225 ~3.49 miles south of 14221
  • 2 star Airport property
  • Check-in: 3:00 PM
More Photos Exterior of Quality Inn Airport
From$80
Poor 2.0 /5 Review Score Call BookMore Details
Aloft Buffalo Airport
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
4219 Genesee St., Cheektowaga, NY 14225 ~3.54 miles south of 14221
  • 3-star Airport hotel
  • Hotel has a green policy Learn more
More Photos Image of Aloft Buffalo Airport
From$88
Average 3.0 /5 Review Score Call BookMore Details
Candlewood Suites Buffalo - Amherst by IHG
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
20 Flint Rd., Amherst, NY 14226 ~3.55 miles west of 14221
  • Low-priced Suburban hotel
  • 76 rooms in property
More Photos Exterior of Candlewood Suites Buffalo - Amherst by IHG
From$60
Very Good 4.5 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Buffalo/Amherst in Amherst
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1138 Millersport Highway, Amherst, NY 14226 ~3.60 miles west of 14221
  • 3 star Suburban property
  • Airport shuttle provided
More Photos Image of Homewood Suites by Hilton Buffalo/Amherst
From$118
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
131 Buell Ave., Cheektowaga, NY 14225 ~3.67 miles south of 14221
  • 3-star Airport hotel
  • Airport shuttle available
More Photos Exterior of Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
From$79
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Clarence Inn
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
9079 Main St., Clarence, NY 14032 ~3.73 miles east of 14221
  • 3 star Airport property
  • 14 rooms in property
More Photos Photo of Clarence Inn
From$48
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Extended Stay of America : 901 Dick Rd.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
901 Dick Rd., Cheektowaga, NY 14225 ~3.78 miles south of 14221
  • Mid-scale Airport hotel
  • Complimentary breakfast is offered
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Amherst, NY - Buffalo : 4400 Maple Rd.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4400 Maple Rd., Amherst, NY 14226 ~3.94 miles west of 14221
  • Low-priced hotel
  • 2 floors in hotel
More Photos Photo of Motel 6 Amherst, NY - Buffalo
From$60
Average 3.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Buffalo Airport : 760 Dick Rd.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
760 Dick Rd., Cheektowaga, NY 14225 ~3.97 miles south of 14221
  • Mid-scale Airport property
  • Shuttle from airport available
More Photos Photo of Homewood Suites by Hilton Buffalo Airport
From$104
Very Good 4.5 /5 Read Reviews Call BookMore Details
Staybridge Suites Buffalo Amherst in Amherst
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1290 Sweet Home Rd., Amherst, NY 14228 ~4.03 miles west of 14221
  • Midscale Suburban property
  • Free complimentary breakfast
More Photos Photo of Staybridge Suites Buffalo Amherst
From$85
Very Good 4.5 /5 Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Amherst/University
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
3880 Rensch Rd. Amherst Ny 14228, Amherst, NY 14228 ~4.04 miles west of 14221
  • Three Star Suburban hotel
  • Gym is available on property
More Photos Exterior of Fairfield Inn & Suites by Marriott Buffalo Amherst/University
From$54
Excellent 5.0 /5 Read Reviews Call BookMore Details
Village Haven Inn & Extended Stay - Clarence
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
9370 Main St., Clarence, NY 14031 ~4.26 miles east of 14221
  • Low-priced property
More Photos Image of Village Haven Inn & Extended Stay
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
University Manor Inn
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
3612 Main St., Buffalo, NY 14226 ~4.79 miles west of 14221
  • Low-priced Downtown hotel
  • 2 suites in hotel
More Photos Exterior of University Manor Inn
From$40
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La Quinta Inn & Suites by Wyndham Buffalo Amherst
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
145 Innkeepers Lane, Buffalo, NY 14228 ~4.97 miles west of 14221
  • Affordable Suburban property
  • Fitness / Gym is on-site
More Photos Photo of La Quinta Inn & Suites by Wyndham Buffalo Amherst
From$80
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Tonawanda/Buffalo in Tonawanda
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1120 Niagarafalls Blvd., Tonawanda, NY 14150 ~4.97 miles west of 14221
  • 2 star Suburban property
  • 51 rooms in hotel
More Photos Photo of Days Inn by Wyndham Tonawanda/Buffalo
From$60
Poor 2.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Buffalo Amherst
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
125 Inn Keepers Ln., Amherst, NY 14228 ~5.03 miles west of 14221
  • Low-priced hotel
  • Fitness + Health Center
More Photos Exterior of Extended Stay America Suites Buffalo Amherst
From$52
Average 3.0 /5 Reviews Call BookMore Details
Home2 Suites by Hilton Amherst Buffalo
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3820 Ridge Lea Rd., Amherst, NY 14228 ~5.07 miles west of 14221
  • Affordable Suburban property
  • Check in: 3:00 pm
More Photos Exterior of Home2 Suites by Hilton Amherst Buffalo
From$60
Very Good 4.0 /5 Read Reviews Call BookMore Details
Sleep Inn - Amherst
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
75 Inn Keepers Lane, Amherst, NY 14228 ~5.17 miles west of 14221
  • 2-star Suburban hotel
  • 92 sleeping rooms in hotel
More Photos Exterior of Sleep Inn
From$75
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Baymont by Wyndham Buffalo : 3475 Union Rd.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
3475 Union Rd., Buffalo, NY 14225 ~5.18 miles south of 14221
  • Low priced property
  • Check-in time: 4pm
More Photos Photo of Baymont by Wyndham Buffalo
From$75
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M Hotel : 2040 Walden Ave.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2040 Walden Ave., Buffalo, NY 14225 ~5.22 miles south of 14221
  • Economy Airport property
  • Fitness center on property
More Photos Exterior of M Hotel
From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Amherst Inn & Suites in Amherst
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
1951 Niagara Falls Blvd., Amherst, NY 14228 ~5.23 miles west of 14221
  • Cheap Downtown hotel
  • Free breakfast available
More Photos Exterior of Amherst Inn & Suites
From$60
Average 3.5 /5 Read Reviews Call BookMore Details

Next: Show All Available 14221 Hotels with Pricing

Graph of Williamsville, NY Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Williamsville, NY discounts available. The chart reflects the cheapest Williamsville hotel for each day and each star rating category.

FAQs about hotels near 14221

What are the most favored hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Candlewood Suites Buffalo - Amherst by IHG and Homewood Suites by Hilton Buffalo Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 14221?

The Mosey Hotel a Tapestry Collection by Hilton, Buffalo Marriott Niagara and Jazzboline are the top 3 luxury hotels near 14221.

What hotels are closest to the area of 14221?

La Quinta Inn by Wyndham Buffalo Airport, Hawthorn Suites by Wyndham Williamsville Buffalo Airport, and Springhill Suites Buffalo Airport are the properties closest to 14221.

How much does a cheap hotel near 14221 cost per night?

In the last year, a 2 star hotel near 14221 can be as cheap as $74.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 14221 cost per night?

In the last year, the average 3 star hotel near 14221 has been $97.89 per night. (based on HotelPlanner prices)

How much does a high-end hotel near 14221 cost?

In the last year, the average 4 star hotel near 14221 has been $140.50 per night. (based on HotelPlanner prices)

What are the best independent hotels near 14221?

Jazzboline, Inn at Buffalo Airport and Clarence Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Springhill Suites Buffalo Airport and Courtyard by Marriott Buffalo Amherst are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 14221?

Sleep Inn Buffalo Airport, Comfort Inn University and Sleep Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 14221?

Candlewood Suites Buffalo - Amherst by IHG, Staybridge Suites Buffalo Amherst and Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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