Star Rating
Hotel Name
Price Range (USD) to
Amenities
+ More

14221 Hotels, Motels & Accommodations

La Quinta Inn by Wyndham Buffalo Airport - Williamsville
+1-888-389-4121
6619 Transit Rd., Williamsville, NY 14221
  • Low Cost Airport property
  • Check in: 03:00 PM
From$79
Average 3.0 /5 Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 14221" Get Alexa Skill →
Hawthorn Suites by Wyndham Williamsville Buffalo Airport - Williamsville
+1-888-675-2083
8005 Sheridan Dr., Williamsville, IN 14221
  • Affordable Airport hotel
  • 98 suites in property
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Springhill Suites Buffalo Airport - Buffalo
+1-800-716-8490
6647 Transit Rd., Buffalo, NY 14221
  • 3 star Suburban property
  • 2 suites in property
From$79
Very Good 4.0 /5 Read Reviews Call BookMore Details
Fairbridge Inn Express Buffalo Airport Williamsville - Williamsville
+1-800-805-5223
7200 Transit Rd., Williamsville, NY 14221
  • Two-star Airport property
  • Check in: 3pm
From$60
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn Buffalo-Williamsville - Williamsville
+1-888-965-1860
5455 Main St., Williamsville, NY 14221
  • Three Star Suburban property
  • Free breakfast
From$95
Very Good 4.0 /5 Reviews Call BookMore Details
The Mosey Hotel a Tapestry Collection by Hilton
+1-888-788-5576
5195 Main St., Buffalo, NY 14221
  • Four star Suburban hotel
  • Gym is available on property
From$69
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Tru by Hilton Williamsville Buffalo Airport in Williamsville
+1-888-897-9207
48 Freeman Rd. Building A, Williamsville, NY 14221
  • Three Star Airport property
  • Check-in time: 3:00 PM
From$75
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Buffalo Ny Airport Williamsville in Buffalo
+1-888-311-4278
52 Freeman Rd., Buffalo, NY 14221
  • Economical Airport property
  • Check-in time: 15:00
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western Buffalo Inn & Suites : 50 Freeman Rd.
+1-888-469-4795
50 Freeman Rd., Buffalo, NY 14221
  • Midscale Airport property
  • Check in: 03:00
From$73
Average 3.0 /5 Review Score Call BookMore Details
Garden Place Hotel - Williamsville
+1-888-734-9421
6615 Transit Rd., Williamsville, NY 14221
  • 3 star Airport hotel
  • Hotel has 166 rooms
From$81
Average 3.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Buffalo Amherst / University : 4100 Sheridan Dr.
+1-888-841-5292
4100 Sheridan Dr., Buffalo, NY 14221
  • Mid-scale Suburban property
  • Fitness center on property
From$119
Very Good 4.0 /5 Read Reviews Call BookMore Details
Residence Inn Buffalo Amherst : 100 Maple Rd.
+1-888-455-5160
100 Maple Rd., Amherst, NY 14221
  • Midscale Suburban property
  • Free breakfast
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Amherst / Buffalo in Buffalo
+1-888-965-8297
1601 Amherst Manor Dr., Buffalo, NY 14221
  • Affordable Suburban property
  • Free complimentary breakfast
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Buffalo Marriott Niagara
+1-888-906-6358
1340 Millersport Highway, Amherst, NY 14221
  • 4 star Suburban property
  • 17 meeting rooms in hotel
From$125
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Buffalo/Amherst - Amherst
+1-888-749-6785
5020 Main St., Amherst, NY 14226 ~2.50 miles southwest of 14221
  • Affordable Suburban property
  • Hotel has 3 suites
From$95
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Need some questions answered? Talk to an expert Hotel Planner: (855) 276-7561 or say...
alexa hotel planner skill"Alexa, ask Hotel Planner to make a new reservation in 14221" Get Alexa Skill →
Jazzboline - Amherst
+1-888-878-9982
5010 Main St., Amherst, NY 14226 ~2.68 miles southwest of 14221
  • High-end property
From$75
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Buffalo - Niagara Airport
+1-888-389-4485
146 Maple Dr., Bowmansville, NY 14026 ~2.69 miles southeast of 14221
  • Inexpensive Airport property
  • Check in: 12:00 PM
From$82
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Reikart House, Buffalo, a Tribute Portfolio Hotel - Amherst
+1-888-389-4121
5000 Main St., Amherst, NY 14226 ~2.71 miles southwest of 14221
  • Expensive Suburban property
  • Check-in: 3:00 PM
From$129
Very Good 4.0 /5 Reviews Call BookMore Details
Sleep Inn Buffalo Airport - Cheektowaga
+1-888-675-2083
100 Holtz Dr., Cheektowaga, NY 14225 ~3.01 miles south of 14221
  • 2 star Airport property
  • Complimentary breakfast is offered
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Inn at Buffalo Airport : 4630 Genesee St.
+1-800-716-8490
4630 Genesee St., Cheektowaga, NY 14225 ~3.14 miles south of 14221
  • Low-priced Airport hotel
  • 78 rooms in property
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Buffalo Airport Hotel in Cheektowaga
+1-800-805-5223
4600 Genesee St., Cheektowaga, NY 14225 ~3.15 miles south of 14221
  • 3-star Airport hotel
  • Airport shuttle available
From$49
Average 3.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Buffalo Airport : 4345 Genesee St.
+1-888-965-1860
4345 Genesee St., Buffalo, NY 14225 ~3.33 miles south of 14221
  • 3 star Suburban property
  • 129 rooms in property
From$99
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Airport
+1-888-788-5576
4271 Genesee St., Buffalo, NY 14225 ~3.34 miles south of 14221
  • Midscale Airport property
  • 4 meeting rooms in hotel
From$107
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard Buffalo Airport - Cheektowaga
+1-888-897-9207
4243 Genesee St., Cheektowaga, NY 14225 ~3.40 miles south of 14221
  • 3 star Airport property
  • 5 suites in property
From$97
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn University
+1-888-311-4278
1 Flint Rd., Amherst, NY 14226 ~3.42 miles west of 14221
  • Low priced Suburban property
  • Free complimentary breakfast
From$55
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn Buffalo Airport - Buffalo
+1-888-469-4795
4201 Genesee St., Buffalo, NY 14225 ~3.46 miles south of 14221
  • Midscale Airport property
  • 158 sleeping rooms in hotel
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
DoubleTree by Hilton Hotel Buffalo - Amherst in Amherst
+1-888-734-9421
10 Flint Rd., Amherst, NY 14226 ~3.46 miles west of 14221
  • High end Suburban hotel
  • Hotel has 3 meeting rooms
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Red Roof Inn PLUS+ University at Buffalo - Amherst in Amherst
+1-888-841-5292
42 Flint Rd., Amherst, NY 14226 ~3.47 miles west of 14221
  • Cheap Suburban hotel
  • 108 rooms in hotel
Towneplace Suites Buffalo Airport in Buffalo
+1-888-455-5160
4265 Genesee St., Buffalo, NY 14225 ~3.48 miles south of 14221
  • 3-star Airport property
  • 120 rooms in hotel
From$109
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Inn Airport - Buffalo
+1-888-965-8297
4217 Genesee St., Buffalo, NY 14225 ~3.49 miles south of 14221
  • Economical Airport hotel
  • Hotel has 2 floors
Aloft Buffalo Airport in Cheektowaga
+1-888-906-6358
4219 Genesee St., Cheektowaga, NY 14225 ~3.54 miles south of 14221
  • 3-star Airport hotel
  • Airport shuttle provided
From$88
Average 3.0 /5 Latest Reviews Call BookMore Details
Candlewood Suites Buffalo - Amherst by IHG in Amherst
+1-888-749-6785
20 Flint Rd., Amherst, NY 14226 ~3.55 miles west of 14221
  • Two star Suburban property
  • Hotel has a green policy See policy
From$60
Very Good 4.5 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Buffalo/Amherst : 1138 Millersport Highway
+1-888-878-9982
1138 Millersport Highway, Amherst, NY 14226 ~3.60 miles west of 14221
  • Three Star Suburban hotel
  • 93 suites in property
From$118
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Buffalo-Airport, an IHG Hotel
+1-888-389-4485
131 Buell Ave., Cheektowaga, NY 14225 ~3.67 miles south of 14221
  • 3 star Airport property
  • Fitness + Health Center
From$79
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Clarence Inn
+1-888-389-4121
9079 Main St., Clarence, NY 14032 ~3.73 miles east of 14221
  • Mid-scale Airport hotel
  • Check-in time: 4pm
From$48
Very Good 4.0 /5 Review Score Call BookMore Details
Extended Stay of America : 901 Dick Rd.
+1-888-675-2083
901 Dick Rd., Cheektowaga, NY 14225 ~3.78 miles south of 14221
  • Three Star Airport property
  • 100 suites in property
From$80
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Amherst, NY - Buffalo
+1-800-716-8490
4400 Maple Rd., Amherst, NY 14226 ~3.94 miles west of 14221
  • 2-star hotel
  • 93 rooms in property
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Buffalo Airport - Cheektowaga
+1-800-805-5223
760 Dick Rd., Cheektowaga, NY 14225 ~3.97 miles south of 14221
  • Three Star Airport hotel
  • 77 suites in property
From$104
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Staybridge Suites Buffalo Amherst : 1290 Sweet Home Rd.
+1-888-965-1860
1290 Sweet Home Rd., Amherst, NY 14228 ~4.03 miles west of 14221
  • Mid-scale Suburban hotel
  • 102 suites in hotel
From$85
Very Good 4.5 /5 Review Score Call BookMore Details
Fairfield Inn & Suites by Marriott Buffalo Amherst/University
+1-888-788-5576
3880 Rensch Rd. Amherst Ny 14228, Amherst, NY 14228 ~4.04 miles west of 14221
  • Three Star Suburban property
  • Fitness / Gym is on-site
From$54
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Village Haven Inn & Extended Stay : 9370 Main St.
+1-888-897-9207
9370 Main St., Clarence, NY 14031 ~4.26 miles east of 14221
  • Inexpensive property
  • 40 rooms in hotel
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
University Manor Inn : 3612 Main St.
+1-888-311-4278
3612 Main St., Buffalo, NY 14226 ~4.79 miles west of 14221
  • Inexpensive Downtown property
  • Check in time: 1500
From$40
Average 3.0 /5 Hotel Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Buffalo Amherst
+1-888-469-4795
145 Innkeepers Lane, Buffalo, NY 14228 ~4.97 miles west of 14221
  • Midscale Suburban hotel
  • Comp. Breakfast
From$80
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Tonawanda/Buffalo : 1120 Niagarafalls Blvd.
+1-888-734-9421
1120 Niagarafalls Blvd., Tonawanda, NY 14150 ~4.97 miles west of 14221
  • Cheap Suburban property
  • 2 floors in property
Extended Stay America Suites Buffalo Amherst : 125 Inn Keepers Ln.
+1-888-841-5292
125 Inn Keepers Ln., Amherst, NY 14228 ~5.03 miles west of 14221
  • Economical property
  • 119 rooms in hotel
From$52
Average 3.0 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Amherst Buffalo : 3820 Ridge Lea Rd.
+1-888-455-5160
3820 Ridge Lea Rd., Amherst, NY 14228 ~5.07 miles west of 14221
  • 3-star Suburban property
  • Comp. Breakfast
From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Sleep Inn : 75 Inn Keepers Lane
+1-888-965-8297
75 Inn Keepers Lane, Amherst, NY 14228 ~5.17 miles west of 14221
  • 2-star Suburban hotel
  • Check-in: 3:00 PM
From$75
Very Good 4.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Buffalo - Buffalo
+1-888-906-6358
3475 Union Rd., Buffalo, NY 14225 ~5.18 miles south of 14221
  • Two star property
  • 56 sleeping rooms in hotel
From$75
Average 3.0 /5 Recent Reviews Call BookMore Details
M Hotel
+1-888-749-6785
2040 Walden Ave., Buffalo, NY 14225 ~5.22 miles south of 14221
  • Economy Airport property
  • Shuttle from airport available
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Amherst Inn & Suites
+1-888-878-9982
1951 Niagara Falls Blvd., Amherst, NY 14228 ~5.23 miles west of 14221
  • Two star Downtown hotel
  • Free breakfast available
From$60
Average 3.5 /5 Reviews Call BookMore Details

Next: Show All Available 14221 Hotels with Pricing

Graph of Williamsville, NY Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Williamsville, NY discounts available. The chart reflects the cheapest Williamsville hotel for each day and each star rating category.

FAQs about hotels near 14221

What are the most favored hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Candlewood Suites Buffalo - Amherst by IHG and Homewood Suites by Hilton Buffalo Airport are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels near 14221?

The Mosey Hotel a Tapestry Collection by Hilton, Buffalo Marriott Niagara and Jazzboline are the top 3 luxury hotels near 14221.

What hotels are closest to the area of 14221?

La Quinta Inn by Wyndham Buffalo Airport, Hawthorn Suites by Wyndham Williamsville Buffalo Airport, and Springhill Suites Buffalo Airport are the properties closest to 14221.

How much does a cheap hotel near 14221 cost per night?

In the last year, a 2 star hotel near 14221 can be as cheap as $74.66 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 14221 cost per night?

In the last year, the average 3 star hotel near 14221 has been $97.89 per night. (based on HotelPlanner prices)

How much does a high-end hotel near 14221 cost?

In the last year, the average 4 star hotel near 14221 has been $140.50 per night. (based on HotelPlanner prices)

What are the best independent hotels near 14221?

Jazzboline, Inn at Buffalo Airport and Clarence Inn are the best rated independent hotels (not part of a big brand).

What are the best Marriott hotels near 14221?

Fairfield Inn & Suites by Marriott Buffalo Amherst, Springhill Suites Buffalo Airport and Courtyard by Marriott Buffalo Amherst are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels near 14221?

Sleep Inn Buffalo Airport, Comfort Inn University and Sleep Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels near 14221?

Candlewood Suites Buffalo - Amherst by IHG, Staybridge Suites Buffalo Amherst and Holiday Inn Express Hotel & Suites Buffalo-Airport, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Back to Top