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49221 Hotels/Accommodations

Super 8
+1-888-389-4121
1091 West Us 223, Adrian, MI 49221
  • Low Cost Downtown hotel
  • Hotel has an eco-friendly policy Read more
From$39
Average 3.0 /5 Latest Reviews Call BookMore Details
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Travelodge by Wyndham Adrian
+1-888-675-2083
1575 West Maumee St., Adrian, MI 49221
  • 2 star Suburban property
  • Check in time: 2 pm
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Carlton Lodge Adrian - Adrian
+1-800-716-8490
1629 West Maumee St., Adrian, MI 49221
  • Three Star Rural property
  • 14 suites in property
From$64
Average 3.5 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites Adrian - Adrian
+1-800-805-5223
425 Industrial Dr., Adrian, MI 49221
  • Mid-scale hotel
From$69
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Amp Suites Adrian : 1335 South Main St.
+1-888-965-1860
1335 South Main St., Adrian, MI 49221
  • Three Star property
  • Check in time: 15:00
From$90
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Adrian
+1-888-788-5576
1091 Us Highway 223, Adrian, MI 49221
  • Inexpensive Downtown property
  • Free breakfast
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Adrian by IHG
+1-888-897-9207
1077 East Us Highway 223, Adrian, MI 49221
  • Affordable Rural property
  • Check in time: 3:00 p
From$129
Very Good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Brooklyn - Brooklyn
+1-888-311-4278
419 South Main / M50, Brooklyn, MI 49230 ~16.07 miles northwest of 49221
  • Cheap property
From$60
Average 3.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites : 401 Powell Dr.
+1-888-469-4795
401 Powell Dr., Dundee, MI 48131 ~20.18 miles east of 49221
  • Midscale Rural hotel
  • Check-in: 3:00pm
From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI
+1-888-734-9421
665 Tecumseh, Dundee, MI 48131 ~20.24 miles east of 49221
  • 3 star Rural hotel
  • 69 rooms in hotel
From$81
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Dundee - Dundee
+1-888-841-5292
102 Whitetail Dr., Dundee, MI 48131 ~20.34 miles east of 49221
  • Three Star Highway property
  • 40 suites in hotel
From$82
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn : 111 Waterstradt Commerce Dr.
+1-888-455-5160
111 Waterstradt Commerce Dr., Dundee, MI 48131 ~20.35 miles east of 49221
  • 2 star Rural hotel
  • 2 suites in hotel
From$49
Average 3.0 /5 Recent Reviews Call BookMore Details
American Inn and Suites Dundee : 130 Outer Dr.
+1-888-965-8297
130 Outer Dr., Dundee, MI 48131 ~20.52 miles east of 49221
  • Affordable Highway property
  • 2 suites in property
From$80
Average 3.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Wauseon
+1-888-906-6358
8319 Oh 108, Wauseon, OH 43567 ~22.24 miles south of 49221
  • Two-star Rural property
  • 6 suites in hotel
From$48
Average 3.5 /5 Recent Reviews Call BookMore Details
M Star Hotel Wauseon - Wauseon
+1-888-749-6785
8225 State Rd. 108, Wauseon, OH 43567 ~22.29 miles south of 49221
  • Mid-scale property
  • Hotel has 35 rooms
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Rodeway Inn
+1-888-878-9982
8224 State Route 108, Wauseon, OH 43567 ~22.30 miles south of 49221
  • 2-star Highway property
  • 20 sleeping rooms in hotel
From$45
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Wauseon by IHG
+1-888-389-4485
8135 State Route 108, Wauseon, OH 43567 ~22.41 miles south of 49221
  • Midscale property
  • 15 suites in property
From$100
Average 3.0 /5 Hotel Reviews Call BookMore Details
Wingate by Wyndham Sylvania / Toledo in Sylvania
+1-888-389-4121
5480 South Main St., Sylvania, OH 43560 ~22.94 miles southeast of 49221
  • 3 star Suburban hotel
  • 74 sleeping rooms in hotel
From$88
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Milan
+1-888-675-2083
1230 Dexter St., Milan, MI 48160 ~23.81 miles northeast of 49221
  • Low-priced Suburban hotel
  • Hotel has 8 suites
From$55
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Saline
+1-800-716-8490
1250 East Michigan Ave., Saline, MI 48176 ~24.20 miles northeast of 49221
  • Three Star Highway hotel
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Baymont Inn & Suites by Wyndham Swanton/Toledo Airport - Swanrton
+1-800-805-5223
10753 Airport Highway, Swanrton, OH 43558 ~25.44 miles southeast of 49221
  • Two-star hotel
  • Check-in: 11:00 AM
From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn Chelsea
+1-888-965-1860
1645 Commerce Park Dr., Chelsea, MI 48118 ~27.06 miles north of 49221
  • Mid-scale Highway hotel
  • Fitness center on property
From$83
Average 3.0 /5 Read Reviews Call BookMore Details
Baymont by Wyndham Chelsea in Chelsea
+1-888-788-5576
1540 Commerce Park Dr., Chelsea, MI 48118 ~27.14 miles north of 49221
  • Affordable Highway hotel
  • 20 suites in property
From$69
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Toledo - University - Toledo
+1-888-897-9207
3530 Executive Pkwy., Toledo, OH 43606 ~27.50 miles southeast of 49221
  • Economical Downtown hotel
  • Has environment-friendly policy See policy
From$46
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Toledo : 3560 Secor Rd.
+1-888-311-4278
3560 Secor Rd., Toledo, OH 43606 ~27.58 miles southeast of 49221
  • 2 star property
  • Fitness + Health Center
Residence Inn Toledo Marriott in Toledo
+1-888-469-4795
3554 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • Mid-scale property
  • Fitness + Health Center
From$90
Very Good 4.0 /5 Reviews Call BookMore Details
Courtyard Toledo West - Toledo
+1-888-734-9421
3536 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • 3-star Suburban hotel
  • Free breakfast available
From$99
Average 3.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Airport - Holland
+1-888-841-5292
1201 East Mall Dr., Holland, OH 43528 ~27.61 miles southeast of 49221
  • Economy Suburban property
  • 4 suites in hotel
From$36
Poor 2.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Toledo West by IHG in Toledo
+1-888-455-5160
3440 Secor Rd., Toledo, OH 43606 ~27.65 miles southeast of 49221
  • 3-star Suburban property
  • Hotel has 106 rooms
From$109
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn & Suites Toledo/Westgate - Toledo
+1-888-965-8297
3434 Secor Rd., Toledo, OH 43606 ~27.68 miles southeast of 49221
  • 3-star Suburban property
  • 4 floors in hotel
From$119
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Toledo - Holland
+1-888-906-6358
1214 Corporate Dr., Holland, OH 43528 ~27.80 miles southeast of 49221
  • Economical Suburban property
  • 106 rooms in property
Quality Inn Toledo Airport
+1-888-749-6785
1401 East Mall Dr., Holland, OH 43528 ~27.87 miles southeast of 49221
  • 2 star Airport hotel
  • Check in time: 3:00pm
From$49
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 Ann Arbor : 3764 South State St.
+1-888-878-9982
3764 South State St., Ann Arbor, MI 48108 ~27.88 miles northeast of 49221
  • Low priced hotel
  • Check in: 15:00
From$46
Average 3.0 /5 Review Score Call BookMore Details
Toledo Holland Courtyard Marriott - Holland
+1-888-389-4485
1435 East Mall Dr., Holland, OH 43528 ~27.90 miles southeast of 49221
  • 3-star Suburban property
  • Gym is available on property
From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Ann Arbor- Univ of Michigan by IHG in Ann Arbor
+1-888-389-4121
3850 Research Park Dr., Ann Arbor, MI 48108 ~27.90 miles northeast of 49221
  • 3 star Highway hotel
  • Hotel has 130 suites
From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Towneplace Suites by Marriott Ann Arbor
+1-888-675-2083
1301 Briarwood Circle Dr., Ann Arbor, MI 48108 ~27.95 miles northeast of 49221
  • Cheap Golf Course property
  • Comp. Breakfast
From$150
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Exp Stes University Sou
+1-800-716-8490
3853 Research Park Dr., Ann Arbor, MI 48108 ~27.99 miles northeast of 49221
  • Three Star property
  • 94 rooms in hotel
From$90
Very Good 4.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Ann Arbor
+1-800-805-5223
1401 Briarwood Circle, Ann Arbor, MI 48108 ~28.00 miles northeast of 49221
  • 3 star Highway hotel
  • Hotel has 4 floors
From$119
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Sonesta Simply Suites Detroit Ann Arbor in Ann Arbor
+1-888-965-1860
701 Waymarket Way, Ann Arbor, MI 48103 ~28.03 miles northeast of 49221
  • 3-star Suburban property
  • Gym is available on property
From$66
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Toledo Holland
+1-888-788-5576
6155 Trust Dr., Holland, OH 43528 ~28.06 miles southeast of 49221
  • 3-star Suburban property
  • Check in time: 3:00 PM
From$53
Average 3.0 /5 Recent Reviews Call BookMore Details
Hawthorn Suites by Wyndham Holland/Toledo Area : 6101 Trust Dr.
+1-888-897-9207
6101 Trust Dr., Holland, OH 43528 ~28.10 miles southeast of 49221
  • Mid-scale Airport property
  • 2 floors in hotel
From$45
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Even Hotels Ann Arbor An Ihg Hotel - Ann Arbor
+1-888-311-4278
600 Briarwood Circle, Ann Arbor, MI 48108 ~28.14 miles northeast of 49221
  • 3 star Suburban hotel
  • 4 floors in property
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Knights Inn Maumee : 1520 South Holland Sylvania Rd.
+1-888-469-4795
1520 South Holland Sylvania Rd., Maumee, OH 43537 ~28.26 miles southeast of 49221
  • 3-star Highway hotel
  • 63 sleeping rooms in hotel
From$32
Average 3.0 /5 Latest Reviews Call BookMore Details
The Kensington Hotel - Ann Arbor
+1-888-734-9421
3500 South State St., Ann Arbor, MI 48108 ~28.27 miles northeast of 49221
  • Three Star Suburban hotel
  • 3 suites in property
From$104
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Knights Inn Maumee : 1520s Holland Sylvania Rd.
+1-888-841-5292
1520s Holland Sylvania Rd., Maumee, OH 43537 ~28.27 miles southeast of 49221
  • Two star Highway property
  • 160 rooms in hotel
From$42
Average 3.0 /5 Recent Reviews Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South : 3505 South State St.
+1-888-455-5160
3505 South State St., Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • Two-star Downtown hotel
  • Check in time: 3:00 PM
From$29
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn & Suites University South
+1-888-965-8297
3501 South State, Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • Low Cost Suburban property
  • Check-in time: 3:00
From$67
Average 3.0 /5 Guest Reviews Call BookMore Details
Sonesta Es Suites Ann Arbor - Ann Arbor
+1-888-906-6358
800 Victors Way, Ann Arbor, MI 48108 ~28.37 miles northeast of 49221
  • Affordable Highway property
  • Access to gym on-site
From$99
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Ann Arbor : 3223 South State St.
+1-888-749-6785
3223 South State St., Ann Arbor, MI 48108 ~28.42 miles northeast of 49221
  • Affordable Downtown property
  • Fitness + Health Center
From$99
Average 3.0 /5 Reviews Call BookMore Details
Sheraton Ann Arbor Hotel
+1-888-878-9982
3200 Boardwalk, Ann Arbor, MI 48108 ~28.43 miles northeast of 49221
  • Mid-scale Suburban hotel
  • Check in: 03:00 PM
From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details

Next: Show All Available 49221 Hotels with Pricing

Graph: Next 20 Days of Adrian Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Adrian, MI discounts available. The chart reflects the cheapest Adrian hotel for each day and each star rating category.

FAQs about hotels near 49221

What are the most favored hotels near 49221?

Travelodge by Wyndham Adrian, Holiday Inn Express Adrian by IHG and Hampton Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 49221?

Carlton Lodge Adrian, Comfort Inn & Suites Adrian and Hampton Inn & Amp Suites Adrian are the top 3 luxury hotels near 49221.

What hotels are closest to the area of 49221?

Super 8, Travelodge by Wyndham Adrian, and Carlton Lodge Adrian are the properties closest to 49221.

How much does a cheap hotel near 49221 cost per night?

In the last year, a 2 star hotel near 49221 can be as cheap as $54.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 49221 cost per night?

In the last year, the average 3 star hotel near 49221 has been $112.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 49221?

Dundee, Even Hotels Ann Arbor An Ihg Hotel and The Kensington Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 49221?

Residence Inn Toledo Marriott, Toledo Holland Courtyard Marriott and Towneplace Suites by Marriott Ann Arbor are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 49221?

Quality Inn, Rodeway Inn and Comfort Inn Chelsea are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 49221?

Holiday Inn Express Adrian by IHG, Holiday Inn Express & Suites Toledo West by IHG and Staybridge Suites Ann Arbor- Univ of Michigan by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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