Hotels in 49221 - Adrian MI

Only hotels in 49221 zip code are listed below. Search for cheap and discount hotel rates in Adrian, MI for your upcoming leisure or conference / group travel. We list the best 49221 hotels and motels so you can review the Adrian hotel list below to find the perfect lodging. Hotels in Lenawee county and area code 517 are also listed.

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49221 Hotels/Motels & Accommodations

Super 8 : 1091 West Us 223
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1091 West Us 223, Adrian, MI 49221
  • Two star Downtown property
  • Check-in: 3:00 pm
More Photos Exterior of Super 8
From$39
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Travelodge by Wyndham Adrian in Adrian
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1575 West Maumee St., Adrian, MI 49221
  • 2-star Suburban property
  • Check in: 2 pm
More Photos Image of Travelodge by Wyndham Adrian
From$60
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Carlton Lodge Adrian
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1629 West Maumee St., Adrian, MI 49221
  • 3 star Rural property
  • 98 sleeping rooms in hotel
More Photos Exterior of Carlton Lodge Adrian
From$64
Average 3.5 /5 Hotel Reviews Call BookMore Details
Comfort Inn & Suites Adrian : 425 Industrial Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
425 Industrial Dr., Adrian, MI 49221
  • 3-star property
More Photos Exterior of Comfort Inn & Suites Adrian
From$69
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Amp Suites Adrian : 1335 South Main St.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1335 South Main St., Adrian, MI 49221
  • Mid-scale property
More Photos hotel room
From$90
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Adrian
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1091 Us Highway 223, Adrian, MI 49221
  • Two-star Downtown hotel
  • Check in time: 3:00 pm
More Photos Image of Super 8 by Wyndham Adrian
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express Adrian by IHG
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1077 East Us Highway 223, Adrian, MI 49221
  • 3 star Rural property
  • Free complimentary breakfast
More Photos Exterior of Holiday Inn Express Adrian by IHG
From$129
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Brooklyn - Brooklyn
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
419 South Main / M50, Brooklyn, MI 49230 ~16.07 miles northwest of 49221
  • Cheap property
More Photos hotel room
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites - Dundee
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
401 Powell Dr., Dundee, MI 48131 ~20.18 miles east of 49221
  • Midscale Rural property
  • Check in time: 3:00pm
More Photos Image of Hampton Inn & Suites
From$80
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Country Inn & Suites by Radisson, Dundee, MI
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
665 Tecumseh, Dundee, MI 48131 ~20.24 miles east of 49221
  • Midscale Rural hotel
  • 69 rooms in hotel
More Photos Photo of Country Inn & Suites by Radisson, Dundee, MI
From$81
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Dundee
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
102 Whitetail Dr., Dundee, MI 48131 ~20.34 miles east of 49221
  • Midscale Highway hotel
  • Check-in: 4pm
More Photos Exterior of Dundee
From$82
Very Good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn : 111 Waterstradt Commerce Dr.
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
111 Waterstradt Commerce Dr., Dundee, MI 48131 ~20.35 miles east of 49221
  • Cheap Rural hotel
  • Free comp. breakfast
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From$49
Average 3.0 /5 Hotel Reviews Call BookMore Details
American Inn and Suites Dundee - Dundee
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
130 Outer Dr., Dundee, MI 48131 ~20.52 miles east of 49221
  • Affordable Highway property
  • Hotel has 2 suites
More Photos Exterior of American Inn and Suites Dundee
From$80
Average 3.0 /5 Reviews Call BookMore Details
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Days Inn by Wyndham Wauseon : 8319 Oh 108
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
8319 Oh 108, Wauseon, OH 43567 ~22.24 miles south of 49221
  • Low-priced Rural hotel
  • Free breakfast available
More Photos Image of Days Inn by Wyndham Wauseon
From$48
Average 3.5 /5 Guest Reviews Call BookMore Details
M Star Hotel Wauseon
+1-888-749-6785

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New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8225 State Rd. 108, Wauseon, OH 43567 ~22.29 miles south of 49221
  • Mid-scale hotel
  • 35 rooms in property
More Photos Exterior of M Star Hotel Wauseon
From$90
Poor 2.0 /5 Hotel Reviews Call BookMore Details
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Rodeway Inn - Wauseon
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
8224 State Route 108, Wauseon, OH 43567 ~22.30 miles south of 49221
  • Low-priced Highway hotel
  • Check in time: 1:30Pm
More Photos Photo of Rodeway Inn
From$45
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Holiday Inn Express & Suites Wauseon by IHG - Wauseon
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
8135 State Route 108, Wauseon, OH 43567 ~22.41 miles south of 49221
  • Three Star hotel
  • Fitness + Health Center
More Photos Photo of Holiday Inn Express & Suites Wauseon by IHG
From$100
Average 3.0 /5 Guest Reviews Call BookMore Details
Wingate by Wyndham Sylvania / Toledo
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
5480 South Main St., Sylvania, OH 43560 ~22.94 miles southeast of 49221
  • Midscale Suburban property
  • 4 floors in property
More Photos Image of Wingate by Wyndham Sylvania / Toledo
From$88
Very Good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Milan in Milan
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1230 Dexter St., Milan, MI 48160 ~23.81 miles northeast of 49221
  • Low priced Suburban hotel
  • 63 sleeping rooms in hotel
More Photos Exterior of Baymont by Wyndham Milan
From$55
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Saline
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1250 East Michigan Ave., Saline, MI 48176 ~24.20 miles northeast of 49221
  • 3 star Highway hotel
  • Comp. Breakfast
More Photos hotel room
From$80
Average 3.0 /5 Review Score Call BookMore Details
Baymont Inn & Suites by Wyndham Swanton/Toledo Airport
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
10753 Airport Highway, Swanrton, OH 43558 ~25.44 miles southeast of 49221
  • Cheap hotel
  • Check in: 11:00 AM
More Photos Photo of Baymont Inn & Suites by Wyndham Swanton/Toledo Airport
From$59
Average 3.0 /5 Review Score Call BookMore Details
Comfort Inn Chelsea
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1645 Commerce Park Dr., Chelsea, MI 48118 ~27.06 miles north of 49221
  • Three Star Highway hotel
  • Complimentary breakfast is offered
More Photos Photo of Comfort Inn Chelsea
From$83
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Chelsea : 1540 Commerce Park Dr.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1540 Commerce Park Dr., Chelsea, MI 48118 ~27.14 miles north of 49221
  • Midscale Highway property
  • Hotel has 3 floors
More Photos Image of Baymont by Wyndham Chelsea
From$69
Average 3.0 /5 Read Reviews Call BookMore Details
Red Roof Inn Toledo - University
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
3530 Executive Pkwy., Toledo, OH 43606 ~27.50 miles southeast of 49221
  • Inexpensive Downtown property
  • 3 floors in hotel
More Photos Image of Red Roof Inn Toledo - University
From$46
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Toledo in Toledo
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
3560 Secor Rd., Toledo, OH 43606 ~27.58 miles southeast of 49221
  • Two-star property
  • 70 sleeping rooms in hotel
More Photos Image of Quality Inn Toledo
From$69
Poor 2.0 /5 Guest Reviews Call BookMore Details
Residence Inn Toledo Marriott
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
3554 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • 3-star property
  • 110 rooms in property
More Photos Exterior of Residence Inn Toledo Marriott
From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Toledo West - Toledo
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
3536 Secor Rd., Toledo, OH 43606 ~27.59 miles southeast of 49221
  • 3 star Suburban property
  • Hotel has an eco-friendly policy Learn more
More Photos Exterior of Courtyard Toledo West
From$99
Average 3.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Airport - Holland - Holland
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1201 East Mall Dr., Holland, OH 43528 ~27.61 miles southeast of 49221
  • Cheap Suburban hotel
  • Free breakfast available
More Photos Photo of Econo Lodge Airport - Holland
From$36
Poor 2.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Toledo West by IHG - Toledo
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3440 Secor Rd., Toledo, OH 43606 ~27.65 miles southeast of 49221
  • 3-star Suburban property
  • 106 rooms in property
More Photos Photo of Holiday Inn Express & Suites Toledo West by IHG
From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn & Suites Toledo/Westgate : 3434 Secor Rd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3434 Secor Rd., Toledo, OH 43606 ~27.68 miles southeast of 49221
  • 3 star Suburban property
  • Hotel has 17 suites
More Photos Exterior of Hampton Inn & Suites Toledo/Westgate
From$119
Very Good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Toledo - Holland - Holland
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1214 Corporate Dr., Holland, OH 43528 ~27.80 miles southeast of 49221
  • Low priced Suburban property
  • 2 floors in hotel
More Photos Image of Red Roof Inn Toledo - Holland
From$37
Poor 2.0 /5 Guest Reviews Call BookMore Details
Quality Inn Toledo Airport in Holland
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1401 East Mall Dr., Holland, OH 43528 ~27.87 miles southeast of 49221
  • Low-priced Airport property
  • Check in: 3:00pm
More Photos Exterior of Quality Inn Toledo Airport
From$49
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 Ann Arbor
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3764 South State St., Ann Arbor, MI 48108 ~27.88 miles northeast of 49221
  • Economy hotel
More Photos Image of Motel 6 Ann Arbor
From$46
Average 3.0 /5 Review Score Call BookMore Details
Toledo Holland Courtyard Marriott
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1435 East Mall Dr., Holland, OH 43528 ~27.90 miles southeast of 49221
  • 3 star Suburban hotel
  • Airport shuttle provided
More Photos Image of Toledo Holland Courtyard Marriott
From$89
Very Good 4.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Ann Arbor- Univ of Michigan by IHG
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3850 Research Park Dr., Ann Arbor, MI 48108 ~27.90 miles northeast of 49221
  • Affordable Highway property
  • 4 meeting rooms in hotel
More Photos Photo of Staybridge Suites Ann Arbor- Univ of Michigan by IHG
From$119
Very Good 4.0 /5 Read Reviews Call BookMore Details
Towneplace Suites by Marriott Ann Arbor in Ann Arbor
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1301 Briarwood Circle Dr., Ann Arbor, MI 48108 ~27.95 miles northeast of 49221
  • Two star Golf Course hotel
  • 97 rooms in property
More Photos Image of Towneplace Suites by Marriott Ann Arbor
From$150
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Exp Stes University Sou : 3853 Research Park Dr.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
3853 Research Park Dr., Ann Arbor, MI 48108 ~27.99 miles northeast of 49221
  • 3 star property
  • Check-in: 15:00
More Photos Exterior of Holiday Inn Exp Stes University Sou
From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn Ann Arbor
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
1401 Briarwood Circle, Ann Arbor, MI 48108 ~28.00 miles northeast of 49221
  • 3-star Highway property
  • Hotel has 130 rooms
More Photos Image of Hilton Garden Inn Ann Arbor
From$119
Very Good 4.0 /5 Read Reviews Call BookMore Details
Sonesta Simply Suites Detroit Ann Arbor
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
701 Waymarket Way, Ann Arbor, MI 48103 ~28.03 miles northeast of 49221
  • Three Star Suburban hotel
  • 122 suites in property
More Photos Photo of Sonesta Simply Suites Detroit Ann Arbor
From$66
Very Good 4.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Toledo Holland : 6155 Trust Dr.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
6155 Trust Dr., Holland, OH 43528 ~28.06 miles southeast of 49221
  • Affordable Suburban property
  • 3 floors in property
More Photos Image of Extended Stay America Suites Toledo Holland
From$53
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hawthorn Suites by Wyndham Holland/Toledo Area
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
6101 Trust Dr., Holland, OH 43528 ~28.10 miles southeast of 49221
  • Mid-scale Airport hotel
  • Free breakfast
More Photos Exterior of Hawthorn Suites by Wyndham Holland/Toledo Area
From$45
Very Good 4.0 /5 Read Reviews Call BookMore Details
Even Hotels Ann Arbor An Ihg Hotel
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
600 Briarwood Circle, Ann Arbor, MI 48108 ~28.14 miles northeast of 49221
  • 3-star Suburban hotel
  • 107 rooms in hotel
More Photos Image of Even Hotels Ann Arbor An Ihg Hotel
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Knights Inn Maumee : 1520 South Holland Sylvania Rd.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1520 South Holland Sylvania Rd., Maumee, OH 43537 ~28.26 miles southeast of 49221
  • 3 star Highway hotel
  • Check-in time: 14:00am
More Photos Image of Knights Inn Maumee
From$32
Average 3.0 /5 Read Reviews Call BookMore Details
The Kensington Hotel
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
3500 South State St., Ann Arbor, MI 48108 ~28.27 miles northeast of 49221
  • Affordable Suburban hotel
  • Hotel has 3 floors
More Photos Exterior of The Kensington Hotel
From$104
Very Good 4.0 /5 Read Reviews Call BookMore Details
Knights Inn Maumee in Maumee
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1520s Holland Sylvania Rd., Maumee, OH 43537 ~28.27 miles southeast of 49221
  • Low priced Highway property
  • Check-in time: 14:00am
More Photos Exterior of Knights Inn Maumee
From$42
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Ann Arbor - University of Michigan South
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3505 South State St., Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • Low-priced Downtown property
  • Hotel has 2 floors
More Photos Exterior of Red Roof Inn Ann Arbor - University of Michigan South
From$29
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Inn & Suites University South
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
3501 South State, Ann Arbor, MI 48108 ~28.33 miles northeast of 49221
  • Low-priced Suburban property
  • Check in time: 3:00
More Photos Photo of Comfort Inn & Suites University South
From$67
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sonesta Es Suites Ann Arbor in Ann Arbor
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
800 Victors Way, Ann Arbor, MI 48108 ~28.37 miles northeast of 49221
  • Three Star Highway hotel
  • 114 suites in property
More Photos Image of Sonesta Es Suites Ann Arbor
From$99
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hyatt Place Ann Arbor
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
3223 South State St., Ann Arbor, MI 48108 ~28.42 miles northeast of 49221
  • Mid-scale Downtown property
  • Fitness + Health Center
More Photos Photo of Hyatt Place Ann Arbor
From$99
Average 3.0 /5 Latest Reviews Call BookMore Details
Sheraton Ann Arbor Hotel
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
3200 Boardwalk, Ann Arbor, MI 48108 ~28.43 miles northeast of 49221
  • Midscale Suburban property
  • Hotel has 196 rooms
More Photos Photo of Sheraton Ann Arbor Hotel
From$109
Very Good 4.0 /5 Latest Reviews Call BookMore Details

Next: Show All Available 49221 Hotels with Pricing

Graph: Next 20 Days of Adrian Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Adrian, MI discounts available. The chart reflects the cheapest Adrian hotel for each day and each star rating category.

FAQs about hotels near 49221

What are the most favored hotels near 49221?

Travelodge by Wyndham Adrian, Holiday Inn Express Adrian by IHG and Hampton Inn & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most high-end hotels near 49221?

Carlton Lodge Adrian, Comfort Inn & Suites Adrian and Hampton Inn & Amp Suites Adrian are the top 3 luxury hotels near 49221.

What hotels are closest to the area of 49221?

Super 8, Travelodge by Wyndham Adrian, and Carlton Lodge Adrian are the properties closest to 49221.

How much does a cheap hotel near 49221 cost per night?

In the last year, a 2 star hotel near 49221 can be as cheap as $54.93 per night. (based on HotelPlanner prices)

How much does a 3 star hotel near 49221 cost per night?

In the last year, the average 3 star hotel near 49221 has been $112.99 per night. (based on HotelPlanner prices)

What are the most popular independent hotels near 49221?

Dundee, Even Hotels Ann Arbor An Ihg Hotel and The Kensington Hotel are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels near 49221?

Residence Inn Toledo Marriott, Toledo Holland Courtyard Marriott and Towneplace Suites by Marriott Ann Arbor are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the most popular Choice Hotels branded hotels near 49221?

Quality Inn, Rodeway Inn and Comfort Inn Chelsea are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular IHG hotels near 49221?

Holiday Inn Express Adrian by IHG, Holiday Inn Express & Suites Toledo West by IHG and Staybridge Suites Ann Arbor- Univ of Michigan by IHG are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

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