Potosi Missouri Hotels & Motels

Only hotels in Potosi are listed below. Find discounted hotel accommodations in or close to Potosi, MO for your upcoming personal or group trip. We list the best Potosi, Missouri hotel and motel rooms. Browse the Potosi area hotels to find the perfect lodging! Please use the provided map of the Potosi hotels. Group booking? Search Potosi Group Hotel Rates

Potosi is a city that breathes a unique mix of history, culture, and natural beauty, making it a must-visit destination for every traveler. Located about an hour south of St. Louis, it's well-placed for a quick getaway from the city. Nearby towns like Farmington and Bonne Terre add options for more exploring. Blanketed by rolling hills and lush forests, the city is a haven for outdoor enthusiasts. Potosi's rich tapestry of history is woven into its attractions, such as the nearby Washington State Park. For thrill-seekers, the city offers the captivating Mark Twain National Forest, known for its hiking, biking, and camping opportunities against a backdrop of mesmerizing landscapes. At the heart of Potosi, you can find a downtown area with a blend of quaint boutiques, art galleries, and local eateries that offer a taste of Missouri's culinary heritage. Visitors can also immerse themselves in the city's arts scene, with regular music and arts festivals painting the town with a vivacious hue. Beyond the sights and attractions, Potosi ensures a comfortable stay for its visitors. The area boasts a range of accommodation options to suit diverse budgets and preferences, including cozy motels, charming inns, and spacious suites. Many are located close to the town's main attractions, allowing easy access for sightseeing. In addition, the city's strategic location makes it a convenient base for exploring the broader region of Missouri. More from this guide...

Potosi Hotels, Motels & Accommodations

Super 8 by Wyndham Potosi : 820 East High St. 820 East High St., Potosi, MO 63664 Call
  • Low-priced Highway property
  • Check in: 2 pm
From£36
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre 8 Northwood Dr., Bonne Terre, MO 63628 Call ~16.74 miles east of Potosi
  • Economical property
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 Bonne Terre Mo - Bonne Terre 1017 Highway K, Bonne Terre, MO 63628 Call ~16.77 miles east of Potosi
  • Cheap property
From£44
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Club Vac Timber Creek - Desoto 4800 Us Highway 67, Desoto, MO 63020 Call ~21.05 miles east of Potosi
  • Three Star hotel
  • Check in: 16:00
From£66
Very good 4.5 /5 Recent Reviews Call BookMore Details
Crown Pointe Lodge, BW Signature Collection 4245 Hunt Rd., Farmington, MO 63640 Call ~23.63 miles east of Potosi
  • Affordable Golf Course hotel
  • Hotel has a green policy See policy
From£45
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Farmington in Farmington 850 Valley Creek Dr., Farmington, MO 63640 Call ~24.48 miles east of Potosi
  • Mid-scale Highway property
  • Free comp. breakfast
From£59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Farmington in Farmington 930 Valley Creek Dr., Farmington, MO 63640 Call ~24.55 miles east of Potosi
  • Low-priced property
  • 60 rooms in hotel
From£36
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Farmington by IHG in Farmington 820 Market St., Farmington, MO 63640 Call ~24.66 miles east of Potosi
  • Mid-scale Rural hotel
  • 60 rooms in hotel
From£73
Very good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn Farmington : 1400 West Liberty St. 1400 West Liberty St., Farmington, MO 63640 Call ~24.77 miles east of Potosi
  • Affordable Rural property
  • Check in: 11:00
From£59
Average 3.0 /5 Review Score Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO : 1625 West Columbia St. 1625 West Columbia St., Farmington, MO 63640 Call ~25.04 miles southeast of Potosi
  • Three Star Highway property
  • 2 floors in property
From£59
Average 3.0 /5 Read Reviews Call BookMore Details
Comfort Inn - Sullivan 736 South Service Rd. West, Sullivan, MO 63080 Website Call ~25.15 miles northwest of Potosi
  • 3-star Highway property
  • 3 floors in property
From£74
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Sullivan 601 North Service Rd., Sullivan, MO 63080 Call ~25.22 miles northwest of Potosi
  • Low Cost hotel
From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Americas Best Value Inn Sullivan - Sullivan 307 North Service Rd., Sullivan, MO 63080 Call ~25.26 miles northwest of Potosi
  • Low-priced property
  • Free complimentary breakfast
From£32
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 Sullivan, MO 209 North Service Rd., Sullivan, MO 63080 Call ~25.32 miles northwest of Potosi
  • Two star property
  • Check in: 3
From£44
Average 3.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Sullivan 275 North Service Rd. West, Sullivan, MO 63080 Call ~25.36 miles northwest of Potosi
  • Economical Rural hotel
  • Check-in: 3:00
From£44
Average 3.0 /5 Guest Reviews Call BookMore Details
Pinemark Inn & Suites 866 South Outer Rd., St. Clair, MO 63077 Call ~28.90 miles north of Potosi
  • 2 star Highway property
  • 3 suites in property
From£45
Very good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham St. Clair MO in Saint Clair 1010 South Outer Rd., Saint Clair, MO 63077 Call ~28.98 miles north of Potosi
  • 2 star Highway property
  • Free breakfast available
From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Festus South St. Louis by Ih - Festus 1802 Gamel Cemetery Rd., Festus, MO 63028 Call ~29.33 miles northeast of Potosi
  • 2-star Highway hotel
  • 23 suites in hotel
From£66
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Baymont by Wyndham Festus - Festus 1200 West Gannon Dr., Festus, MO 63028 Call ~29.54 miles northeast of Potosi
  • 3 star Suburban property
  • Fitness center on property
From£53
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Festus St. Louis South in Festus 1303 Veterans Blvd., Festus, MO 63028 Website Call ~29.55 miles northeast of Potosi
  • Three Star Suburban hotel
  • Check-in: 3:00 PM
From£33
Very good 4.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Festus - St. Louis South : 1001 Veterans Blvd. 1001 Veterans Blvd., Festus, MO 63028 Call ~29.75 miles northeast of Potosi
  • Three Star Suburban hotel
  • Free complimentary breakfast
From£59
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn & Suites by Wyndham Cuba 97 Ozark Dr., Cuba, MO 65453 Call ~31.59 miles west of Potosi
  • Economy Highway property
  • Fitness center on property
From£40
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Cuba : 28 Highway P 28 Highway P, Cuba, MO 65453 Call ~31.83 miles west of Potosi
  • Economical Rural property
  • Check-in: 2 PM
From£59
Very good 4.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Pevely - Pevely 1711 Highway Z, Pevely, MO 63070 Call ~32.95 miles northeast of Potosi
  • Two-star hotel
  • Check in: 11:00 AM
From£25
Very good 4.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Union in Union 1015 East Main St., Union, MO 63084 Call ~34.90 miles north of Potosi
  • Two-star Rural hotel
From£49
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Near Six Flags St. Louis 1400 West Osage St., Pacific, MO 63069 Call ~36.79 miles north of Potosi
  • Mid-scale Rural hotel
  • Check in: 11:00
From£59
Very good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Inn Near Six Flags St. Louis 1320 Thornton St., Pacific, MO 63069 Website Call ~36.94 miles north of Potosi
  • 3-star Highway property
  • Free comp. breakfast
From£65
Average 3.0 /5 Hotel Reviews Call BookMore Details
America's Best Inn Eureka 1725 West 5th St., Eureka, MO 63025 Call ~39.13 miles north of Potosi
  • Two star Highway hotel
  • Check-in time: 11.00am
Super 8 by Wyndham Eureka/Six Flags Nearby in Eureka 1733 West 5th St., Eureka, MO 63025 Call ~39.17 miles north of Potosi
  • Two star Highway property
From£44
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn St. Louis West Six Flags by IHG - Eureka 4901 Six Flags Rd., Eureka, MO 63025 Call ~39.24 miles north of Potosi
  • Midscale Suburban hotel
  • 4 meeting rooms in property
From£95
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites in Arnold 3610 West Outer Rd., Arnold, MO 63010 Website Call ~40.04 miles northeast of Potosi
  • Low priced Suburban hotel
  • 19 suites in hotel
From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western Plus Washington Hotel : 2621 East 5th St. 2621 East 5th St., Washington, MO 63090 Call ~40.82 miles north of Potosi
  • Midscale Suburban property
  • Comp. Breakfast
From£45
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Washington in Washington 2081 Eckelkamp Court, Washington, MO 63090 Call ~40.98 miles north of Potosi
  • Economical property
  • Check in time: 03:00PM
From£44
Very good 4.0 /5 Reviews Call BookMore Details
Woodspring Suites St. Louis Arnold - Arnold 888 Arnold Commons Dr., Arnold, MO 63010 Call ~41.45 miles northeast of Potosi
  • Cheap Highway property
  • 124 rooms in property
From£23
Very good 4.0 /5 Recent Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve in Ste. Genevieve 21958 State Highway 32, Ste. Genevieve, MO 63670 Call ~42.66 miles east of Potosi
  • 2-star Highway hotel
  • Free breakfast available
From£37
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western St. Louis Inn in Saint Louis 6224 Heimos Industrial Park Dr., Saint Louis, MO 63129 Call ~43.33 miles northeast of Potosi
  • Low priced Suburban property
  • Check-in time: 03:00
From£29
Average 3.0 /5 Recent Reviews Call BookMore Details
680 Fenton Business Park Ct Fenton Missouri 63026 Fenton Business Park Court Fenton, Fenton, IA 63026 Call ~43.43 miles northeast of Potosi
  • Affordable hotel
From£59
Average 3.0 /5 Recent Reviews Call BookMore Details
Crossroads Inn And Suites : 1200 South Main St. 1200 South Main St., Salem, MO 65560 Call ~43.84 miles southwest of Potosi
  • 3-star property
  • 4 floors in hotel
From£66
Average 3.0 /5 Review Score Call BookMore Details
Arrowrock Inn - Ste Genevieve 17030 New Bremen Rd., Ste Genevieve, MO 63670 Call ~44.18 miles east of Potosi
  • Low Cost Rural property
  • Free comp. breakfast
From£36
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn St. Louis Southwest 9 Lambert Drury Place, St. Louis, MO 63088 Call ~44.31 miles northeast of Potosi
  • Mid-scale Suburban hotel
  • Free breakfast
From£63
Very good 4.5 /5 Latest Reviews Call BookMore Details
The Wildwood Hotel in Wildwood 2801 Fountain Place, Wildwood, MO 63040 Call ~44.71 miles north of Potosi
  • Expensive Suburban hotel
  • Hotel has 18 suites
From£74
Very good 4.0 /5 Reviews Call BookMore Details
Fairfield Inn N Ste St. Louis South - St Louis 4318 Butler Hill Rd., St Louis, MO 63128 Call ~44.97 miles northeast of Potosi
  • 3-star property
  • Check in time: 15:00
From£66
Average 3.0 /5 Read Reviews Call BookMore Details

Next: See My Potosi Hotels with Pricing

The Prime Seasons to Visit Potosi, MO

In Potosi, summers are hot and muggy, while the winters are very cold and snowy. During the year, the temperature typically varies from 25 °F to 88 °F and rarely drops below 9 °F or rises above 96 °F. Summer in Potosi offers warm weather and longer days, which are ideal for making the most of outdoor adventures. Potosi's numerous lakes and rivers provide ample opportunities for swimming and boating. The city also hosts family-friendly events, arts and crafts fairs, and farmers markets, where you can experience local culture and taste regional delicacies. The highlight is the annual Washington County Fair in August, which features carnival rides, live music, and a parade. While winter may be quieter, it's no less lovely. Winters in Potosi are generally mild, with occasional snow, making it a peaceful time for exploring the historic downtown or visiting the Washington State Park for winter hikes. Whatever the season, Potosi, MO provides a unique and enriching experience for visitors. Each time of year brings its own special experience, ensuring that you'll find plenty to see and do whenever you choose to visit.

Amazing Discounts Available in Potosi, MO

HotelPlanner makes your stay in Potosi, MO even more affordable with its exclusive hotel discounts. Group travelers can take advantage of significant savings through bulk booking discounts, perfect for family reunions, weddings, or corporate retreats. Solo travelers will find exclusive rates and last-minute deals designed to fit tighter budgets without sacrificing comfort. Additionally, HotelPlanner offers enticing package deals that often include complimentary breakfast, discounted rates for extended stays, and special seasonal promotions. These might feature summer travel specials, fall getaway packages, or winter holiday deals, making it easier to plan an affordable trip any time of year. With these varied offers, both groups and solo travelers can enjoy the best accommodations Potosi has to offer while keeping their travel expenses in check.

Potosi, MO: Where Else to Go?

Potosi's local attractions are as diverse as they are exciting, offering unique experiences to visitors of all ages and interests. One of the city's standout attractions is the Edg-Clif Vineyard, Winery, and Brewery. Here, visitors can immerse themselves in the art of winemaking, sample a variety of handcrafted wines, and enjoy the locally brewed beer. Set against the backdrop of stunning landscapes, Edg-Clif offers an unforgettable experience of wine tasting and scenic views. For golf enthusiasts, the Fourche Valley Golf Club is a must-visit. This beautifully maintained championship golf course provides a challenging and enjoyable round for players of all skill levels. Its serene setting amid the rolling hills and lush greenery of Potosi provides a peaceful retreat for a day of golfing. Nature lovers are in for a treat with the St. Joe State Park and the St. Francois State Park. St. Joe State Park, one of the largest parks in Missouri, offers plenty of outdoor activities, including hiking, horseback riding, and off-road vehicle riding. St. Francois State Park, on the other hand, is known for its picturesque beauty and rich history. Hiking enthusiasts will enjoy the park's three hiking trails that meander through its rugged landscapes and feature breathtaking views. The park also provides excellent opportunities for camping, picnicking, and bird watching, making it a fantastic destination for a family outing or a quiet retreat. Potosi's local attractions offer something for everyone, from wine connoisseurs and golfers to outdoor enthusiasts and nature lovers. These destinations are not just places to visit but experiences to cherish.

What did travelers think of the city of Potosi?

Below are reviews of the city of Potosi, MO from an actual visitor's perspective.

"The Huddle House"
Score 4.0 / 5

The Huddle House was excelling! From the service to the food and even the music was great! They were playing ,The Message and my girls and I were singing right along with it. Highly recommend dining there!

Megantravis C., from 08-Oct-2025
"Great Location"
Score 5.0 / 5

Close to everything and the prison.

Sheila F., from 05-Apr-2025
"Antiquing!"
Score 4.0 / 5

A very unique town and one everyone should tour and enjoy for antiquing.. a small town in Missouri you won't want to miss...

Kay O., from 02-Oct-2022
"Loved the city and the surrounding area."
Score 5.0 / 5

Loved the city and the surrounding area.

Ruthann A., from 15-Mar-2022
"Nice Place"
Score 4.0 / 5

The city of Potosi was fine.

Michelle E., from 08-Nov-2021
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