Perryville Missouri Hotels & Motels

Only hotels in Perryville are listed below. Search for cheap and discounted hotel and motel rates in or close to Perryville, MO for your upcoming personal or group trip. We provide the best Perryville, Missouri motel and hotel rooms. Browse the Perryville area hotels to find the perfect lodging! Please use the provided map of the Perryville hotels. Group booking? Search Perryville Group Hotel Rates

Perryville is a small town in Missouri that is full of history and charm. Founded in 1822, Perryville is a lively river town. The community is situated close to the Mississippi River, making it a beautiful destination to visit. Perryville is also a convenient stopping point for travelers looking to explore the Ozarks region of Missouri. In addition, there are plenty of shops and restaurants in the area and a wide range of activities for tourists, including hiking, fishing, and canoeing. Perryville is a hot spot to visit for a weekend getaway or a longer vacation. The town is centrally located in Missouri, which makes it an ideal setting for exploring the state. Plus, there are plenty of restaurants, shops and attractions nearby, so you won't have to go far to find something to do. From luxurious lodgings and inns to cozy suites, there is a resort option for every type of traveler in this area. Wherever you stay, you can be sure that the staff will go above and beyond to ensure that your stay is comfortable and memorable. So book your stay today and start planning your next Perryville adventure. More from this guide...

Perryville Hotels & Accommodations

Super 8 by Wyndham Perryville
+1-888-389-4121
1119 Vincent Dr., Perryville, MO 63775 +1-888-389-4121
  • Cheap Highway property
  • 64 rooms in hotel
From£46
Very good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Perryville - Perryville
+1-888-675-2083
1500 Liberty St., Perryville, MO 63775 +1-888-675-2083
  • 2-star Highway property
  • Free breakfast
From£47
Average 3.5 /5 Review Score Call BookMore Details
Baymont by Wyndham Chester Il in Chester
+1-800-716-8490
2150 State St., Chester, IL 62233 +1-800-716-8490 ~14.01 miles north of Perryville
  • Mid-scale Rural hotel
  • 2 floors in hotel
From£54
Very good 4.0 /5 Reviews Call BookMore Details
Arrowrock Inn - Ste Genevieve
+1-800-805-5223
17030 New Bremen Rd., Ste Genevieve, MO 63670 +1-800-805-5223 ~14.14 miles northwest of Perryville
  • 2-star Rural hotel
  • Hotel has 2 floors
From£38
Very good 4.0 /5 Guest Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve : 21958 Highway 32
+1-888-965-1860
21958 Highway 32, Sainte Genevieve, MO 63670 +1-888-965-1860 ~19.90 miles northwest of Perryville
  • Cheap Highway property
  • 6 suites in hotel
From£59
Very good 4.0 /5 Recent Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri - Jackson
+1-888-788-5576
225 Drury Lane, Jackson, MO 63755 +1-888-788-5576 ~23.69 miles southeast of Perryville
  • Three Star Suburban property
  • Hotel has 4 floors
From£62
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale in Murphysboro
+1-888-897-9207
128 East Walnut St., Murphysboro, IL 62966 +1-888-897-9207 ~28.86 miles east of Perryville
  • Cheap hotel
  • Hotel has 39 rooms
From£38
Poor 2.5 /5 Read Reviews Call BookMore Details
Comfort Suites - Jackson
+1-888-311-4278
2904 Old Orchard Rd., Jackson, 63755 United States +1-888-311-4278 ~29.01 miles southeast of Perryville
  • 4 star Highway hotel
  • Hotel has 64 suites
From£99
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau - Jackson
+1-888-469-4795
2904 Old Orchard Rd., Jackson, MO 63755 Website +1-888-469-4795 ~29.01 miles southeast of Perryville
  • 3-star Highway property
  • Hotel has an eco-friendly policy Learn more
From£51
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau
+1-888-734-9421
3003 South Old Orchard Rd., Jackson, MO 63755 +1-888-734-9421 ~29.11 miles southeast of Perryville
  • Mid-scale Highway hotel
  • Fitness / Gym is on-site
From£67
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Sparta, an IHG Hotel
+1-888-841-5292
1301 North Market St., Sparta, IL 62286 +1-888-841-5292 ~29.90 miles north of Perryville
  • Affordable Rural property
  • Hotel has an eco-friendly policy Read more
From£78
Very good 4.0 /5 Review Score Call BookMore Details
Quality Inn - Cape Girardeau
+1-888-455-5160
2011 North Kingshighway St., Cape Girardeau, MO 63701 Website +1-888-455-5160 ~30.90 miles southeast of Perryville
  • Economical property
  • Hotel has 49 rooms
From£47
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Farmington, an IHG Hotel
+1-888-965-8297
820 Market St., Farmington, MO 63640 +1-888-965-8297 ~31.88 miles west of Perryville
  • 3 star Rural hotel
  • 3 floors in property
From£78
Very good 4.0 /5 Recent Reviews Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO in Farmington
+1-888-906-6358
1625 West Columbia St., Farmington, MO 63640 +1-888-906-6358 ~31.99 miles west of Perryville
  • 3 star Highway hotel
  • 94 rooms in property
From£63
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Farmington in Farmington
+1-888-749-6785
930 Valley Creek Dr., Farmington, MO 63640 +1-888-749-6785 ~32.00 miles west of Perryville
  • Cheap property
  • Complimentary breakfast is offered
From£38
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Farmington in Farmington
+1-888-878-9982
850 Valley Creek Dr., Farmington, MO 63640 +1-888-878-9982 ~32.06 miles west of Perryville
  • Three Star Highway property
  • 3 floors in hotel
From£63
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Farmington : 1400 West Liberty St.
+1-888-389-4485
1400 West Liberty St., Farmington, MO 63640 +1-888-389-4485 ~32.15 miles west of Perryville
  • Affordable Rural hotel
  • 48 sleeping rooms in hotel
From£63
Average 3.0 /5 Hotel Reviews Call BookMore Details
Crown Pointe Lodge, BW Signature Collection : 4245 Hunt Rd.
+1-888-389-4121
4245 Hunt Rd., Farmington, MO 63640 +1-888-389-4121 ~32.54 miles west of Perryville
  • 3-star Golf Course property
  • 48 rooms in property
From£51
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-675-2083
3351 Percy Dr., Cape Girardeau, MO 63701 +1-888-675-2083 ~32.79 miles southeast of Perryville
  • Mid-scale hotel
  • Check-in: 3pm
From£46
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Lodge in Cape Girardeau
+1-800-716-8490
104 South Vantage Dr., Cape Girardeau, MO 63701 +1-800-716-8490 ~32.81 miles southeast of Perryville
  • 3 star Highway hotel
  • Complimentary breakfast is offered
From£63
Average 3.0 /5 Reviews Call BookMore Details
Drury Suites Cape Girardeau in Cape Girardeau
+1-800-805-5223
3303 Campster Dr., Cape Girardeau, MO 63701 +1-800-805-5223 ~32.98 miles southeast of Perryville
  • 3-star Highway hotel
  • Hotel has 86 rooms
From£67
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center - Cape Girardeau
+1-888-965-1860
3248 William St., Cape Girardeau, MO 63701 +1-888-965-1860 ~33.09 miles southeast of Perryville
  • Cheap Highway property
  • Free breakfast available
From£52
Very good 4.0 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West
+1-888-788-5576
103 Cape West Pkwy., Cape Girardeau, MO 63701 +1-888-788-5576 ~33.09 miles southeast of Perryville
  • 2-star hotel
  • Free complimentary breakfast
From£46
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau in Cape Girardeay
+1-888-897-9207
433 Cape West Crossing, Cape Girardeay, MO 63703 +1-888-897-9207 ~33.12 miles southeast of Perryville
  • Affordable property
From£63
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55
+1-888-311-4278
3253 William St., Cape Girardeau, MO 63701 +1-888-311-4278 ~33.16 miles southeast of Perryville
  • Midscale property
  • 102 rooms in property
From£63
Very good 4.5 /5 Review Score Call BookMore Details
Auburn Place Hotel & Suites - Cape Girardeau
+1-888-469-4795
3265 Williams St., Cape Girardeau, MO 63702 +1-888-469-4795 ~33.18 miles southeast of Perryville
  • Three Star Highway property
  • Gym / Fitness Center Available
From£46
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Victorian Inn & Suites
+1-888-734-9421
3256 William St., Cape Girardeau, MO 63703 +1-888-734-9421 ~33.19 miles southeast of Perryville
  • 3 star Golf Course property
  • 5 suites in hotel
From£62
Average 3.0 /5 Read Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East in Cape Girardeau
+1-888-841-5292
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 +1-888-841-5292 ~33.26 miles southeast of Perryville
  • 3-star Highway property
  • 86 rooms in hotel
From£63
Excellent 5.0 /5 Recent Reviews Call BookMore Details
University Inn of Carbondale
+1-888-455-5160
2400 West Main St., Carbondale, IL 62901 +1-888-455-5160 ~33.54 miles east of Perryville
  • Mid-scale property
From£63
Average 3.0 /5 Guest Reviews Call BookMore Details
Candlewood Suites Cape Girardeau, an IHG Hotel - Cape Girardeau
+1-888-965-8297
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 +1-888-965-8297 ~33.98 miles southeast of Perryville
  • Cheap Highway hotel
  • Hotel has a green policy Read more
From£54
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown
+1-888-906-6358
400 Broadway St., Cape Girardeau, MO 63701 +1-888-906-6358 ~34.34 miles southeast of Perryville
  • Three Star Downtown hotel
  • 78 rooms in hotel
From£63
Very good 4.0 /5 Read Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale
+1-888-749-6785
200 West Elm St., Carbondale, IL 62901 +1-888-749-6785 ~35.23 miles east of Perryville
  • Affordable Downtown hotel
  • 99 rooms in hotel
From£78
Very good 4.0 /5 Read Reviews Call BookMore Details
Train Inn
+1-888-878-9982
406 East Stoker St., Carbondale, IL 62901 +1-888-878-9982 ~35.60 miles east of Perryville
  • Three Star Suburban property
  • Hotel has 2 suites
From£39
Very good 4.0 /5 Latest Reviews Call BookMore Details
Carbondale Value Inn & Suites : 700 East Main St.
+1-888-389-4485
700 East Main St., Carbondale, IL 62901 +1-888-389-4485 ~35.81 miles east of Perryville
  • Economy Downtown hotel
  • Check-in: 3:00pm
From£42
Average 3.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Carbondale - Carbondale
+1-888-389-4121
1180 East Main St., Carbondale, IL 62901 +1-888-389-4121 ~36.41 miles east of Perryville
  • Low priced property
  • 2 suites in property
From£46
Average 3.0 /5 Latest Reviews Call BookMore Details
Best Western Saluki Inn : 801 North Giant City Rd.
+1-888-675-2083
801 North Giant City Rd., Carbondale, IL 62902 +1-888-675-2083 ~36.97 miles east of Perryville
  • Three Star Downtown hotel
  • Check-in time: 3:00pm
From£62
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Carbondale University Area
+1-800-716-8490
1415 East Main St., Carbondale, IL 62901 Website +1-800-716-8490 ~37.00 miles east of Perryville
  • Midscale Suburban property
  • 2 suites in property
Americas Best Value Inn & Suites Pinckneyville : 5700 Il 154
+1-800-805-5223
5700 Il 154, Pinckneyville, IL 62274 +1-800-805-5223 ~37.88 miles northeast of Perryville
  • Cheap property
From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Carbondale
+1-888-965-1860
2175 Reed Station Pkwy., Carbondale, IL 62901 +1-888-965-1860 ~37.98 miles east of Perryville
  • 3 star Rural property
  • Free breakfast available
From£63
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Carbondale Conference Center An Ihg Hotel
+1-888-788-5576
2300 Reed Station Pkwy., Carbondale, IL 62901 +1-888-788-5576 ~38.19 miles east of Perryville
  • Mid-scale Rural hotel
  • 5 floors in hotel
From£78
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Carbondale University Area
+1-888-897-9207
2400 Reed Station Pkwy., Carbondale, IL 62901 Website +1-888-897-9207 ~38.31 miles east of Perryville
  • 3 star Suburban property
  • Free comp. breakfast
From£63
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Du Quoin
+1-888-311-4278
1010 S.jefferson Ave., Du Quoin, IL 62832 +1-888-311-4278 ~38.98 miles east of Perryville
  • Economical hotel
  • 38 rooms in hotel
From£42
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hotel 7 Inn Anna in Anna
+1-888-469-4795
100 Richview Dr., Anna, IL 62906 +1-888-469-4795 ~39.07 miles east of Perryville
  • Two star property
From£47
Very good 4.0 /5 Latest Reviews Call BookMore Details
Motel 6 Bonne Terre Mo : 1017 Highway K
+1-888-734-9421
1017 Highway K, Bonne Terre, MO 63628 +1-888-734-9421 ~39.24 miles west of Perryville
  • Two-star property
From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre
+1-888-841-5292
8 Northwood Dr., Bonne Terre, MO 63628 +1-888-841-5292 ~39.31 miles west of Perryville
  • Economy property
  • Check-in time: 11:00 AM
From£47
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Club Vac Timber Creek : 4800 Us Highway 67
+1-888-455-5160
4800 Us Highway 67, Desoto, MO 63020 +1-888-455-5160 ~41.75 miles northwest of Perryville
  • 3-star property
  • 72 suites in property
From£71
Very good 4.5 /5 Review Score Call BookMore Details
Quality Inn Festus in Festus
+1-888-965-8297
1200 West Gannon Dr., Festus, MO 63028 Website +1-888-965-8297 ~44.62 miles northwest of Perryville
  • Mid-scale Suburban property
  • Free comp. breakfast
From£57
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Festus South St. Louis An I
+1-888-906-6358
1802 Gamel Cemetery Rd., Festus, MO 63028 +1-888-906-6358 ~44.87 miles northwest of Perryville
  • Low priced Highway property
  • Fitness center on property
From£71
Very good 4.0 /5 Recent Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Festus - St. Louis South : 1001 Veterans Blvd.
+1-888-749-6785
1001 Veterans Blvd., Festus, MO 63028 +1-888-749-6785 ~44.89 miles northwest of Perryville
  • Mid-scale Suburban property
  • Fitness + Health Center
From£63
Average 3.0 /5 Recent Reviews Call BookMore Details

Next: See My Perryville Hotels with Pricing

The Best Time to Visit Perryville, MO

Perryville is located in the Ozark Highlands of south-central Missouri, about 80 miles south of St. Louis. The area is characterized by hilly, forested terrain. The city lies at an elevation of 1,023 feet above sea level. The climate of Perryville is humid continental, with hot, humid summers and cold, dry winters. The average high temperature in July is 89 °F, and the average low temperature in January is 24 °F. It is located in a valley between two mountains, and the weather is often very different from the surrounding area. Perryville is known for its hot summers and cold winters. Perryville has a high amount of moisture in the air, and the fog is often dense and covers a large area. Fall is the best time to visit Perryville. The weather is cool and comfortable, and the leaves are changing color. Downtown Perryville comes alive during the fall, with festivals and events occurring throughout the season. Perryville is a stunning attraction to enjoy the outdoors.

Discounted Rentals in Perryville, MO

There are always numerous special offers from accommodations in Perryville, MO. Whether it is a discount on your room rate, free breakfast, or a complimentary upgrade, with a little planning, you can get the best deal possible. Discounts on hotel rooms are widely available in Perryville, MO. Many hotels offer discounts for AAA members, seniors, government employees, and military personnel. Perryville is a great place to visit year-round, but hotel discounts are especially plentiful during the shoulder seasons – April through May and September through October. That means you can enjoy all the town has to offer without breaking the bank. However, deals can also be found during the summer and winter months, depending on the hotel and the time of year. For example, many hotels offer discounts for stays during the week, rather than on weekends.

Mayfest in Perryville, MO: A Celebration of Small-Town America

If you are seeking a fun-filled, family-friendly event to attend this May head over to Perryville and visit the famous Mayfest. The festival features over 200 booths, food, music, a carnival, and entertainment. This annual event has something for everyone, including a carnival, live music, food vendors, and much more. This is a great opportunity to explore Perryville, so you'll be able to take in all the sights and sounds of this historic city. So mark your calendars and make your plans to attend Mayfest in Perryville, Missouri.

Perry Park Center: A Community Hub in Perryville, MO

Perry Park Center is a family-friendly destination in Perryville, MO that offers a wide selection of activities for tourists of all ages. There is something for everyone at Perry Park Center, whether you're after a spot to relax and take in the scenery or an adrenaline-pumping adventure. The center offers distinct amenities, including a playground, picnic pavilion, and walking trails. Perry Park Center is an awesome site to spend a day with the family. There is something for everyone to enjoy, so come and explore all that the center has to offer. Perry Park Center is a great spot to visit if you are looking for a place to enjoy the outdoors.

What did travelers think of the city of Perryville?

Below are reviews of the city of Perryville, MO from an actual visitor's perspective.

"Love the town!"
Score 4.0 / 5

Love the town!

Valorrey H., from 01-Oct-2024
"Nice town with great restaurants."
Score 4.0 / 5

Nice small town. Restaurants were great.

Marvin P., from 10-Jul-2024
"Nice Hotel"
Score 4.0 / 5

I am from Perryville and have my family here but I live away. I like coming to visit and this hotel makes it easier!

Cynthia P., from 11-Jun-2024
"St. Louis Aquarium"
Score 4.0 / 5

Only stayed overnight on way to St. Louis Aquarium which I highly recommend!

Jason C., from 29-Apr-2024
"Nice Small City"
Score 4.0 / 5

People are friendly and it's a nice small city.

Stephanie M., from 30-Sep-2023
"Love It!"
Score 4.0 / 5

I love coming here!

Marilyn K., from 04-Jun-2023
"Tractor Museum"
Score 5.0 / 5

Tractor Museum

Alma N., from 16-Mar-2023
"Lots of food choices!"
Score 5.0 / 5

Lots of food choices!

Crystal C., from 12-Apr-2022
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