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Perryville Missouri Hotels & Motels

Only hotels in Perryville are listed below. Search for cheap and discounted hotel and motel rates in or close to Perryville, MO for your upcoming personal or group trip. We provide the best Perryville, Missouri motel and hotel rooms. Browse the Perryville area hotels to find the perfect lodging! Please use the provided map of the Perryville hotels. Group booking? Search Perryville Group Hotel Rates

Perryville is a small town in Missouri that is full of history and charm. Founded in 1822, Perryville is a lively river town. The community is situated close to the Mississippi River, making it a beautiful destination to visit. Perryville is also a convenient stopping point for travelers looking to explore the Ozarks region of Missouri. In addition, there are plenty of shops and restaurants in the area and a wide range of activities for tourists, including hiking, fishing, and canoeing. Perryville is a hot spot to visit for a weekend getaway or a longer vacation. The town is centrally located in Missouri, which makes it an ideal setting for exploring the state. Plus, there are plenty of restaurants, shops and attractions nearby, so you won't have to go far to find something to do. From luxurious lodgings and inns to cozy suites, there is a resort option for every type of traveler in this area. Wherever you stay, you can be sure that the staff will go above and beyond to ensure that your stay is comfortable and memorable. So book your stay today and start planning your next Perryville adventure. More from this guide...

Perryville Hotels, Motels & Accommodations

Super 8 by Wyndham Perryville - Perryville
+1-888-389-4121
1119 Vincent Dr., Perryville, MO 63775
  • Cheap Highway property
  • 3 floors in property
From$59
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Tired of clicking around? Talk to an expert Hotel Planner: (855) 276-7561 or say...
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Days Inn by Wyndham Perryville - Perryville
+1-888-675-2083
1500 Liberty St., Perryville, MO 63775
  • Inexpensive Highway property
  • Check in: 3:00 PM
From$60
Average 3.5 /5 Read Reviews Call BookMore Details
Best Western Chester Hotel in Chester
+1-800-716-8490
2150 State St., Chester, IL 62233 ~14.01 miles north of Perryville
  • 3-star Rural hotel
  • 46 rooms in hotel
From$69
Very Good 4.0 /5 Reviews Call BookMore Details
Arrowrock Inn in Ste Genevieve
+1-800-805-5223
17030 New Bremen Rd., Ste Genevieve, MO 63670 ~14.14 miles northwest of Perryville
  • Economical Rural hotel
  • Check in: 4:00 pm
From$49
Very Good 4.0 /5 Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Sainte Genevieve
+1-888-965-1860
21958 Highway 32, Sainte Genevieve, MO 63670 ~19.90 miles northwest of Perryville
  • Two star Highway hotel
  • Hotel has 2 floors
From$75
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Drury Inn & Suites Jackson Missouri - Jackson
+1-888-788-5576
225 Drury Lane, Jackson, MO 63755 ~23.69 miles southeast of Perryville
  • 3 star Suburban property
  • Free breakfast
From$79
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Americas Best Value Inn-Murphysboro/Carbondale - Murphysboro
+1-888-897-9207
128 East Walnut St., Murphysboro, IL 62966 ~28.86 miles east of Perryville
  • 2 star hotel
Comfort Suites - Jackson
+1-888-311-4278
2904 Old Orchard Rd., Jackson, 63755 United States ~29.01 miles southeast of Perryville
  • Expensive Highway hotel
  • 3 floors in property
From$125
Average 3.0 /5 Guest Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau
+1-888-469-4795
2904 Old Orchard Rd., Jackson, MO 63755 Website ~29.01 miles southeast of Perryville
  • 3-star Highway property
  • Free complimentary breakfast
From$65
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau
+1-888-734-9421
3003 South Old Orchard Rd., Jackson, MO 63755 ~29.11 miles southeast of Perryville
  • 3-star Highway property
  • 9 suites in property
From$85
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Sparta, an IHG Hotel in Sparta
+1-888-841-5292
1301 North Market St., Sparta, IL 62286 ~29.90 miles north of Perryville
  • 3-star Rural hotel
  • 17 suites in hotel
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn
+1-888-455-5160
2011 North Kingshighway St., Cape Girardeau, MO 63701 Website ~30.90 miles southeast of Perryville
  • Economy hotel
  • 49 sleeping rooms in hotel
From$60
Very Good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Farmington, an IHG Hotel
+1-888-965-8297
820 Market St., Farmington, MO 63640 ~31.88 miles west of Perryville
  • Affordable Rural hotel
  • 20 suites in hotel
From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Baymont Inn and Suites by Wyndham Farmington, MO
+1-888-906-6358
1625 West Columbia St., Farmington, MO 63640 ~31.99 miles west of Perryville
  • Mid-scale Highway property
  • 3 meeting rooms in hotel
From$80
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Farmington - Farmington
+1-888-749-6785
930 Valley Creek Dr., Farmington, MO 63640 ~32.00 miles west of Perryville
  • Low priced hotel
  • Free breakfast
From$49
Average 3.0 /5 Hotel Reviews Call BookMore Details
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Hampton Inn Farmington
+1-888-878-9982
850 Valley Creek Dr., Farmington, MO 63640 ~32.06 miles west of Perryville
  • Three Star Highway hotel
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn Farmington in Farmington
+1-888-389-4485
1400 West Liberty St., Farmington, MO 63640 ~32.15 miles west of Perryville
  • Midscale Rural hotel
  • Check-in time: 11:00
From$80
Average 3.0 /5 Review Score Call BookMore Details
Crown Pointe Lodge, BW Signature Collection : 4245 Hunt Rd.
+1-888-389-4121
4245 Hunt Rd., Farmington, MO 63640 ~32.54 miles west of Perryville
  • 3 star Golf Course hotel
  • Hotel has 17 suites
From$65
Very Good 4.0 /5 Review Score Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-675-2083
3351 Percy Dr., Cape Girardeau, MO 63701 ~32.79 miles southeast of Perryville
  • Midscale hotel
  • Complimentary breakfast is offered
From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Lodge
+1-800-716-8490
104 South Vantage Dr., Cape Girardeau, MO 63701 ~32.81 miles southeast of Perryville
  • 3-star Highway property
  • Check in time: 3:00pm
From$80
Average 3.0 /5 Reviews Call BookMore Details
Drury Suites Cape Girardeau : 3303 Campster Dr.
+1-800-805-5223
3303 Campster Dr., Cape Girardeau, MO 63701 ~32.98 miles southeast of Perryville
  • Affordable Highway property
  • Free complimentary breakfast
From$85
Very Good 4.5 /5 Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West
+1-888-965-1860
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~33.09 miles southeast of Perryville
  • Economical property
  • Complimentary breakfast is offered
From$59
Average 3.0 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center
+1-888-788-5576
3248 William St., Cape Girardeau, MO 63701 ~33.09 miles southeast of Perryville
  • 2 star Highway property
  • Complimentary breakfast is offered
From$66
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 in Cape Girardeau
+1-888-897-9207
3253 William St., Cape Girardeau, MO 63701 ~33.16 miles southeast of Perryville
  • Midscale hotel
  • 102 suites in property
From$80
Very Good 4.5 /5 Reviews Call BookMore Details
Auburn Place Hotel & Suites - Cape Girardeau
+1-888-311-4278
3265 Williams St., Cape Girardeau, MO 63702 ~33.18 miles southeast of Perryville
  • 3 star Highway hotel
  • Fitness + Health Center
From$58
Very Good 4.5 /5 Review Score Call BookMore Details
Victorian Inn & Suites : 3256 William St.
+1-888-469-4795
3256 William St., Cape Girardeau, MO 63703 ~33.19 miles southeast of Perryville
  • Midscale Golf Course hotel
  • 5 suites in hotel
From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East - Cape Girardeau
+1-888-734-9421
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~33.26 miles southeast of Perryville
  • 3-star Highway hotel
  • Hotel has 86 rooms
From$80
Excellent 5.0 /5 Recent Reviews Call BookMore Details
University Inn of Carbondale - Carbondale
+1-888-841-5292
2400 West Main St., Carbondale, IL 62901 ~33.54 miles east of Perryville
  • Midscale hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Candlewood Suites Cape Girardeau, an IHG Hotel
+1-888-455-5160
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~33.98 miles southeast of Perryville
  • Low-priced Highway property
  • Fitness + Health Center
From$69
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown : 400 Broadway St.
+1-888-965-8297
400 Broadway St., Cape Girardeau, MO 63701 ~34.34 miles southeast of Perryville
  • 3 star Downtown hotel
  • Hotel has 5 floors
From$80
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Carbondale - Carbondale
+1-888-906-6358
200 West Elm St., Carbondale, IL 62901 ~35.23 miles east of Perryville
  • Midscale Downtown property
  • Check in: 3:00 pm
From$99
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Train Inn : 406 East Stoker St.
+1-888-749-6785
406 East Stoker St., Carbondale, IL 62901 ~35.60 miles east of Perryville
  • 3 star Suburban property
  • Hotel has 7 rooms
From$50
Very Good 4.0 /5 Review Score Call BookMore Details
Carbondale Value Inn & Suites - Carbondale
+1-888-878-9982
700 East Main St., Carbondale, IL 62901 ~35.81 miles east of Perryville
  • Inexpensive Downtown property
  • Check-in time: 3:00pm
From$54
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Carbondale : 1180 East Main St.
+1-888-389-4485
1180 East Main St., Carbondale, IL 62901 ~36.41 miles east of Perryville
  • 2 star property
  • 3 floors in hotel
From$58
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Saluki Inn
+1-888-389-4121
801 North Giant City Rd., Carbondale, IL 62902 ~36.97 miles east of Perryville
  • Mid-scale Downtown property
  • Comp. Breakfast
From$79
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Carbondale University Area
+1-888-675-2083
1415 East Main St., Carbondale, IL 62901 Website ~37.00 miles east of Perryville
  • 3 star Suburban property
  • Hotel has 2 suites
Americas Best Value Inn & Suites Pinckneyville : 5700 Il 154
+1-800-716-8490
5700 Il 154, Pinckneyville, IL 62274 ~37.88 miles northeast of Perryville
  • Low-priced hotel
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Carbondale
+1-800-805-5223
2175 Reed Station Pkwy., Carbondale, IL 62901 ~37.98 miles east of Perryville
  • Mid-scale Rural hotel
  • Free breakfast available
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Carbondale Conference Center An Ihg Hotel
+1-888-965-1860
2300 Reed Station Pkwy., Carbondale, IL 62901 ~38.19 miles east of Perryville
  • Mid-scale Rural hotel
  • Fitness / Gym is on-site
From$99
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Carbondale University Area
+1-888-788-5576
2400 Reed Station Pkwy., Carbondale, IL 62901 Website ~38.31 miles east of Perryville
  • Affordable Suburban property
  • 73 rooms in hotel
From$80
Average 3.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Du Quoin : 1010 S.jefferson Ave.
+1-888-897-9207
1010 S.jefferson Ave., Du Quoin, IL 62832 ~38.98 miles east of Perryville
  • Economical hotel
  • Check-in time: 3p
From$54
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel 7 Inn Anna : 100 Richview Dr.
+1-888-311-4278
100 Richview Dr., Anna, IL 62906 ~39.07 miles east of Perryville
  • Inexpensive property
From$60
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Motel 6 Bonne Terre Mo
+1-888-469-4795
1017 Highway K, Bonne Terre, MO 63628 ~39.24 miles west of Perryville
  • Two-star property
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham Bonne Terre
+1-888-734-9421
8 Northwood Dr., Bonne Terre, MO 63628 ~39.31 miles west of Perryville
  • 2-star hotel
  • Check in: 11:00 AM
From$60
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Club Vac Timber Creek
+1-888-841-5292
4800 Us Highway 67, Desoto, MO 63020 ~41.75 miles northwest of Perryville
  • Affordable hotel
  • 3 floors in property
From$90
Very Good 4.5 /5 Reviews Call BookMore Details
Quality Inn Festus
+1-888-455-5160
1200 West Gannon Dr., Festus, MO 63028 Website ~44.62 miles northwest of Perryville
  • Midscale Suburban property
  • 7 meeting rooms in hotel
From$72
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Festus South St. Louis An I
+1-888-965-8297
1802 Gamel Cemetery Rd., Festus, MO 63028 ~44.87 miles northwest of Perryville
  • Two-star Highway property
  • Check-in time: 3:00pm
From$90
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Festus - St. Louis South : 1001 Veterans Blvd.
+1-888-906-6358
1001 Veterans Blvd., Festus, MO 63028 ~44.89 miles northwest of Perryville
  • Affordable Suburban hotel
  • Fitness center on property
From$80
Average 3.0 /5 Review Score Call BookMore Details

Next: See My Perryville Hotels with Pricing

Bar Chart: Upcoming 20 Days of Perryville Hotel Rates

Rates shown are nightly rates before taxes and do not necessarily reflect all Perryville, MO discounts available. The chart reflects the cheapest Perryville hotel for each day and each star rating category.

The Best Time to Visit Perryville, MO

Perryville is located in the Ozark Highlands of south-central Missouri, about 80 miles south of St. Louis. The area is characterized by hilly, forested terrain. The city lies at an elevation of 1,023 feet above sea level. The climate of Perryville is humid continental, with hot, humid summers and cold, dry winters. The average high temperature in July is 89 °F, and the average low temperature in January is 24 °F. It is located in a valley between two mountains, and the weather is often very different from the surrounding area. Perryville is known for its hot summers and cold winters. Perryville has a high amount of moisture in the air, and the fog is often dense and covers a large area. Fall is the best time to visit Perryville. The weather is cool and comfortable, and the leaves are changing color. Downtown Perryville comes alive during the fall, with festivals and events occurring throughout the season. Perryville is a stunning attraction to enjoy the outdoors.

Below is a chart of the current pricing seasonality of hotels and motels in Perryville, MO:

Perryville by Star Rating

Below we've posted 3 graphs demonstrating mean nightly cost patterns by star rating class in Perryville, MO. You can use these charts to calculate the best time to make a reservation in Perryville for your upcoming travels.

Top-Notch and Luxury Resort Options in Perryville, MO

When it comes to finding a luxurious vacation rental during your travels, you'll have many options available in Perryville. If you are looking for a premium lodging experience, there are plenty some lodgings offering intimate and personal experiences. These accommodations give you the opportunity to stay in a home away from home while adding some extra comfort on top of it. From 5-star accommodations to stunning views and top-notch service, you'll find everything you need to relax and enjoy your stay. Whether you're planning a romantic getaway or a family vacation, Perryville has the perfect luxury hotel for you.

Low-Budget Vacation Rental Options in Perryville, MO

3 Star Average Prices: $97.93

Perryville is a great option for budget-minded travelers. You'll find no-frills motels and hotels offering basic accommodations at affordable prices. Guests can expect clean rooms and friendly service. Amenities include free breakfasts and Wi-Fi. Guests will also appreciate the spacious rooms and on-site laundry facilities. Perryville, Missouri is also a top spot to visit for camping or RV-ing. The city offers a range of camping and RV sites to choose from, as well as cabins for rent. Whether you're hoping for a rustic camping experience or a more comfortable stay, Perryville has something to offer everyone.

2 Star Average Prices: $69.73

Discounted Rentals in Perryville, MO

There are always numerous special offers from accommodations in Perryville, MO. Whether it is a discount on your room rate, free breakfast, or a complimentary upgrade, with a little planning, you can get the best deal possible. Discounts on hotel rooms are widely available in Perryville, MO. Many hotels offer discounts for AAA members, seniors, government employees, and military personnel. Perryville is a great place to visit year-round, but hotel discounts are especially plentiful during the shoulder seasons – April through May and September through October. That means you can enjoy all the town has to offer without breaking the bank. However, deals can also be found during the summer and winter months, depending on the hotel and the time of year. For example, many hotels offer discounts for stays during the week, rather than on weekends.

Mayfest in Perryville, MO: A Celebration of Small-Town America

If you are seeking a fun-filled, family-friendly event to attend this May head over to Perryville and visit the famous Mayfest. The festival features over 200 booths, food, music, a carnival, and entertainment. This annual event has something for everyone, including a carnival, live music, food vendors, and much more. This is a great opportunity to explore Perryville, so you'll be able to take in all the sights and sounds of this historic city. So mark your calendars and make your plans to attend Mayfest in Perryville, Missouri.

Perry Park Center: A Community Hub in Perryville, MO

Perry Park Center is a family-friendly destination in Perryville, MO that offers a wide selection of activities for tourists of all ages. There is something for everyone at Perry Park Center, whether you're after a spot to relax and take in the scenery or an adrenaline-pumping adventure. The center offers distinct amenities, including a playground, picnic pavilion, and walking trails. Perry Park Center is an awesome site to spend a day with the family. There is something for everyone to enjoy, so come and explore all that the center has to offer. Perry Park Center is a great spot to visit if you are looking for a place to enjoy the outdoors.

FAQs about hotels in Perryville

What are the most favored hotels in Perryville?

Hampton Inn Cape Girardeau I 55 East, Drury Inn & Suites Jackson Missouri and Drury Suites Cape Girardeau are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Perryville?

Comfort Suites, Best Western Chester Hotel and Drury Inn & Suites Jackson Missouri are the top 3 luxury hotels near Perryville city center.

What hotels are closest to the city center of Perryville?

Super 8 by Wyndham Perryville, Days Inn by Wyndham Perryville, and Best Western Chester Hotel are the properties closest to Perryville city center.

How much does a cheap hotel in Perryville cost per night?

In the last year, a 2 star hotel in Perryville can be as cheap as $69.73 per night. (based on HotelPlanner prices)

How much does a 3 star hotel in Perryville cost per night?

In the last year, the average 3 star hotel in Perryville has been $97.93 per night. (based on HotelPlanner prices)

What are the best independent hotels in Perryville?

Drury Suites Cape Girardeau, Auburn Place Hotel & Suites and Arrowrock Inn are the best rated independent hotels (not part of a big brand).

What are the best Choice Hotels branded hotels in Perryville?

Quality Inn, Comfort Suites Jackson-Cape Girardeau and Quality Inn Farmington are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the most popular Best Western hotels in Perryville?

Best Western Chester Hotel, Crown Pointe Lodge, BW Signature Collection and Best Western Saluki Inn are the best rated Best Western branded hotels (based on user reviews score).

What are the best IHG hotels in Perryville?

Holiday Inn Express & Suites Cape Girardeau I 55, Holiday Inn Club Vac Timber Creek and Holiday Inn Express Hotel & Suites Sparta, an IHG Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

What did travelers think of the city of Perryville?

Below are reviews of the city of Perryville, MO from an actual visitor's perspective.

"Love the town!"
Score 4.0 / 5

Love the town!

Valorrey H., from 01-Oct-2024
"Nice town with great restaurants."
Score 4.0 / 5

Nice small town. Restaurants were great.

Marvin P., from 10-Jul-2024
"Nice Hotel"
Score 4.0 / 5

I am from Perryville and have my family here but I live away. I like coming to visit and this hotel makes it easier!

Cynthia P., from 11-Jun-2024
"St. Louis Aquarium"
Score 4.0 / 5

Only stayed overnight on way to St. Louis Aquarium which I highly recommend!

Jason C., from 29-Apr-2024
"Nice Small City"
Score 4.0 / 5

People are friendly and it's a nice small city.

Stephanie M., from 30-Sep-2023
"Love It!"
Score 4.0 / 5

I love coming here!

Marilyn K., from 04-Jun-2023
"Tractor Museum"
Score 5.0 / 5

Tractor Museum

Alma N., from 16-Mar-2023
"Lots of food choices!"
Score 5.0 / 5

Lots of food choices!

Crystal C., from 12-Apr-2022
The average traveler rating of the city of Perryville, MO shown above is 4.3 out of 5 based on 8 reviews
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