Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Accommodations

Country Hearth Inn & Suites Cayce / Columbia : 3020 Charleston Highway 3020 Charleston Highway, Cayce, SC 29033 Call
  • Low-priced property
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From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce 1987 Airport Blvd., Cayce, SC 29033 Call
  • Cheap hotel
  • 117 sleeping rooms in hotel
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From£39
Poor 2.0 /5 Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport - Cayce 1935 Airport Blvd., Cayce, SC 29033 Call
  • Two star Airport hotel
  • Check-in: 3PM
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From£51
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott 613 Knox Abbott Dr., Cayce, NC 29033 Call
  • 3 star property
  • Check-in time: 15:00
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From£55
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport : 650 Cherokee Lane 650 Cherokee Lane, West Columbia, SC 29169 Call ~1.52 miles west of Cayce
  • Inexpensive Airport property
  • Check-in: 2:00 PM
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From£44
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170 Call ~1.66 miles west of Cayce
  • Inexpensive hotel
  • Check in time: 3:00 PM
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From£44
Average 3.0 /5 Review Score Call BookMore Details
Red Roof Inn Columbia, SC Airport 2204 Airport Blvd., West Columbia, SC 29170 Call ~1.70 miles west of Cayce
  • Low-priced Airport property
  • 2 floors in property
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From£48
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170 Call ~1.74 miles west of Cayce
  • Inexpensive Airport property
  • Fitness + Health Center
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From£44
Very good 4.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites Columbia Airport in Cayce 2245 Airport Blvd., Cayce, SC 29033 Call
  • Affordable Airport hotel
  • 64 rooms in property
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From£48
Very good 4.5 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport : 110 Branch Rd. 110 Branch Rd., West Columbia, SC 29170 Call ~1.82 miles west of Cayce
  • Two-star Airport property
  • Airport shuttle provided
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From£44
Poor 2.0 /5 Reviews Call BookMore Details
Clarion Inn Airport West Columbia - West Columbia 29169, West Columbia, SC 29169 Call ~2.17 miles north of Cayce
  • Mid-scale Airport property
  • Fitness center on property
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From£59
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites - West Columbia 3020 Charleston Highway, West Columbia, SC 29172 Call ~2.40 miles south of Cayce
  • 3-star Airport hotel
  • 57 rooms in property
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From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033 Call
  • 3-star Highway property
  • Fitness + Health Center
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From£74
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Columbia Airport in West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website Call ~2.53 miles northwest of Cayce
  • Cheap Airport property
  • 82 rooms in property
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From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Columbia Downtown : 400 Gervais St. 400 Gervais St., Columbia, SC 29214 Call ~2.67 miles northeast of Cayce
  • Midscale property
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From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
TRU by Hilton Columbia Downtown - Columbia 400a Gervais St., Columbia, SC 29214 Call ~2.67 miles northeast of Cayce
  • Midscale hotel
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From£59
Average 3.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Columbia Airport in West Columbia 500 Chris Dr., West Columbia, SC 29169 Call ~2.67 miles northwest of Cayce
  • 3 star Airport hotel
  • Check-in: 3:00pm
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From£38
Very good 4.0 /5 Recent Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection - Columbia 621 South Assembly St., Columbia, SC 29201 Call ~2.80 miles east of Cayce
  • Economical Downtown property
  • 45 rooms in property
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From£44
Average 3.0 /5 Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista - Columbia 511 Lady St., Columbia, SC 29201 Call ~2.83 miles northeast of Cayce
  • 3 star Downtown hotel
  • Complimentary breakfast is offered
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From£74
Very good 4.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC in Columbia 630 Assembly St., Columbia, SC 29201 Call ~2.95 miles northeast of Cayce
  • Affordable Downtown hotel
  • 16 suites in property
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From£74
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Columbia Downtown Historic District 822 Gervais St., Columbia, SC 29201 Call ~3.00 miles northeast of Cayce
  • 3 star Downtown property
  • 5 floors in property
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From£93
Very good 4.5 /5 Read Reviews Call BookMore Details
Hilton Columbia Center : 924 Senate St. 924 Senate St., Columbia, SC 29201 Call ~3.01 miles northeast of Cayce
  • Four star Downtown hotel
  • Fitness + Health Center
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From£75
Very good 4.0 /5 Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista 819 Gervais St., Columbia, SC 29201 Call ~3.02 miles northeast of Cayce
  • Three Star Downtown property
  • Hotel has 2 meeting rooms
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From£59
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown in Columbia 501 Taylor St., Columbia, SC 29201 Call ~3.05 miles north of Cayce
  • Three Star Downtown property
  • 83 rooms in hotel
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From£96
Average 3.0 /5 Recent Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown 823 Lady St., Columbia, SC 29201 Call ~3.06 miles northeast of Cayce
  • Midscale Downtown property
  • Check-in time: 3:00pm
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From£59
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih - Columbia 901 Washington St., Columbia, SC 29201 Call ~3.18 miles northeast of Cayce
  • Midscale hotel
  • Fitness / Gym is on-site
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From£67
Very good 4.0 /5 Recent Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista : 1000 Lady St. 1000 Lady St., Columbia, SC 29201 Website Call ~3.18 miles northeast of Cayce
  • Affordable Downtown hotel
  • Hotel has 4 floors
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From£74
Average 3.0 /5 Review Score Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel : 1913 Huger St. 1913 Huger St., Columbia, SC 29201 Call ~3.26 miles north of Cayce
  • Midscale Downtown hotel
  • 93 sleeping rooms in hotel
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From£81
Very good 4.0 /5 Read Reviews Call BookMore Details
Moxy Columbia - Columbia 1200 Main St., Columbia, SC 29201 Call ~3.31 miles northeast of Cayce
  • Affordable property
  • Check in time: 4:00 PM
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From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Microtel - Columbia 1301 Main St., Columbia, SC 29201 Call ~3.33 miles northeast of Cayce
  • 2 star Downtown property
  • 60 sleeping rooms in hotel
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From£33
Average 3.0 /5 Read Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel 1400 Main St., Columbia, SC 29201 Call ~3.43 miles northeast of Cayce
  • 4-star Downtown property
  • 17 floors in hotel
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From£96
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Columbia Downtown 1233 Washington St., Columbia, SC 29201 Call ~3.47 miles northeast of Cayce
  • Three Star Downtown property
  • 10 floors in property
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From£59
Average 3.0 /5 Reviews Call BookMore Details
Marriott Columbia 1200 Hampton St., Columbia, SC 29201 Call ~3.48 miles northeast of Cayce
  • High-end Downtown property
  • 300 sleeping rooms in hotel
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From£70
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033 Call
  • Economy hotel
  • Check-in: 15:00
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From£44
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone 180 Stoneridge Dr., Columbia, SC 29210 Call ~3.54 miles north of Cayce
  • 2 star Downtown hotel
  • Check-in: 3:00 p.m.
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From£26
Average 3.0 /5 Guest Reviews Call BookMore Details
Hotel Trundle in Columbia 1224 Taylor St., Columbia, SC 29201 Call ~3.56 miles northeast of Cayce
  • Midscale Downtown property
  • 7 suites in property
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From£111
Very good 4.0 /5 Reviews Call BookMore Details
Graduate by Hilton Columbia SC - Columbia 1619 Pendleton St., Columbia, SC 29201 Call ~3.57 miles northeast of Cayce
  • Four-star Downtown property
  • Fitness center on property
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From£96
Average 3.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 in Columbia 450 Gracern Rd., Columbia, SC 29210 Call ~3.57 miles north of Cayce
  • Two-star property
  • Complimentary breakfast is offered
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From£20
Poor 2.0 /5 Latest Reviews Call BookMore Details
Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169 Call ~3.61 miles northwest of Cayce
  • Three Star Highway property
  • Airport shuttle provided
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From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Embassy Suites Columbia 200 Stoneridge Dr., Columbia, SC 29210 Call ~3.65 miles north of Cayce
  • Midscale Suburban hotel
  • Shuttle to airport available
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From£88
Very good 4.0 /5 Recent Reviews Call BookMore Details
TRU by Hilton Columbia Greystone in Columbia 185 Stoneridge Dr., Columbia, SC 29210 Call ~3.66 miles north of Cayce
  • Mid-scale Downtown property
  • 4 floors in hotel
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From£59
Average 3.0 /5 Recent Reviews Call BookMore Details
Carolina University Inn - Columbia 1615 Gervais St., Columbia, SC 29201 Call ~3.66 miles northeast of Cayce
  • Mid-scale Downtown property
  • 89 sleeping rooms in hotel
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From£44
Poor 2.5 /5 Guest Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown : 1609 Gervais St. 1609 Gervais St., Columbia, SC 29201 Call ~3.67 miles northeast of Cayce
  • Three Star property
  • 5 suites in hotel
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From£59
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport : 110 Mcswain Dr. 110 Mcswain Dr., West Columbia, SC 29169 Call ~3.76 miles northwest of Cayce
  • Mid-scale Airport property
  • Fitness center on property
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From£71
Very good 4.0 /5 Reviews Call BookMore Details
Oyo Hotel Columbia Sc West - Columbia 114 Mcswain Dr., Columbia, SC 29169 Call ~3.86 miles northwest of Cayce
  • Mid-scale hotel
  • Check-in: 15:00
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From£67
Very good 4.0 /5 Guest Reviews Call BookMore Details
Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210 Call ~3.91 miles north of Cayce
  • Midscale Downtown hotel
  • 81 sleeping rooms in hotel
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From£56
Average 3.0 /5 Guest Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington : 122 Mathias Rd. 122 Mathias Rd., West Columbia, SC 29169 Call ~4.07 miles northwest of Cayce
  • Affordable Highway property
  • Free breakfast
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From£56
Average 3.0 /5 Review Score Call BookMore Details
Towneplace Suites Columbia West / Lexington - West Columbia 2915 Sunset Blvd., West Columbia, SC 29169 Call ~4.18 miles northwest of Cayce
  • Three Star hotel
  • 111 suites in hotel
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From£56
Very good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210 Call ~5.07 miles north of Cayce
  • 3-star Highway hotel
  • 2 meeting rooms in hotel
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From£46
Very good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Columbia - Columbia 1144 Bush River Rd., Columbia, SC 29210 Call ~5.13 miles northwest of Cayce
  • Two star property
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From£44
Terrible 1.0 /5 Review Score Call BookMore Details

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Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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