Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia 3020 Charleston Highway, Cayce, SC 29033 Call
  • Economy hotel
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From£45
Average 3.0 /5 Guest Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce 1987 Airport Blvd., Cayce, SC 29033 Call
  • 2-star property
  • 2 floors in property
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From£39
Poor 2.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport - Cayce 1935 Airport Blvd., Cayce, SC 29033 Call
  • 2-star Airport property
  • Check in: 3PM
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From£51
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott 613 Knox Abbott Dr., Cayce, NC 29033 Call
  • Affordable hotel
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From£55
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport 650 Cherokee Lane, West Columbia, SC 29169 Call ~1.52 miles west of Cayce
  • Economical Airport hotel
  • 4 floors in hotel
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From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170 Call ~1.66 miles west of Cayce
  • Economy hotel
  • Check-in: 3:00 PM
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From£45
Average 3.0 /5 Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport 2204 Airport Blvd., West Columbia, SC 29170 Call ~1.70 miles west of Cayce
  • Two-star Airport hotel
  • 2 floors in property
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From£48
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Sleep Inn Airport - West Columbia 2208 Airport Blvd., West Columbia, SC 29170 Call ~1.74 miles west of Cayce
  • 2 star Airport hotel
  • 69 rooms in property
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From£45
Very good 4.0 /5 Review Score Call BookMore Details
Country Inn & Suites Columbia Airport : 2245 Airport Blvd. 2245 Airport Blvd., Cayce, SC 29033 Call
  • Three Star Airport hotel
  • Check-in: 15:00
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From£48
Very good 4.5 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport 110 Branch Rd., West Columbia, SC 29170 Call ~1.82 miles west of Cayce
  • Low-priced Airport hotel
  • Shuttle to airport available
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From£45
Poor 2.0 /5 Review Score Call BookMore Details
Clarion Inn Airport West Columbia 29169, West Columbia, SC 29169 Call ~2.17 miles north of Cayce
  • Mid-scale Airport hotel
  • Hotel has 142 rooms
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From£60
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Quality Inn & Suites in West Columbia 3020 Charleston Highway, West Columbia, SC 29172 Call ~2.40 miles south of Cayce
  • Affordable Airport hotel
  • Check-in: 15:00
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From£60
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Courtyard by Marriott Columbia Cayce in Cayce 1125 Fort Congaree Trail, Cayce, SC 29033 Call
  • Affordable Highway property
  • 3 suites in property
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From£74
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn Columbia Airport 2516 Augusta Rd., West Columbia, SC 29169 Website Call ~2.53 miles northwest of Cayce
  • Low priced Airport property
  • Check in time: 3:00
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From£45
Average 3.0 /5 Latest Reviews Call BookMore Details
Clarion Inn Columbia Airport in West Columbia 500 Chris Dr., West Columbia, SC 29169 Call ~2.67 miles northwest of Cayce
  • Mid-scale Airport hotel
  • Free comp. breakfast
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From£39
Very good 4.0 /5 Read Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection in Columbia 621 South Assembly St., Columbia, SC 29201 Call ~2.80 miles east of Cayce
  • Low priced Downtown hotel
  • 45 rooms in hotel
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From£45
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SpringHill Suites by Marriott Columbia Downtown/The Vista 511 Lady St., Columbia, SC 29201 Call ~2.83 miles northeast of Cayce
  • Midscale Downtown hotel
  • Free comp. breakfast
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From£74
Very good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC in Columbia 630 Assembly St., Columbia, SC 29201 Call ~2.95 miles northeast of Cayce
  • 3 star Downtown property
  • Check in time: 4pm
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From£74
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District 822 Gervais St., Columbia, SC 29201 Call ~3.00 miles northeast of Cayce
  • 3 star Downtown hotel
  • Free complimentary breakfast
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From£93
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Hilton Columbia Center - Columbia 924 Senate St., Columbia, SC 29201 Call ~3.01 miles northeast of Cayce
  • Expensive Downtown property
  • 13 suites in property
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From£75
Very good 4.0 /5 Review Score Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista 819 Gervais St., Columbia, SC 29201 Call ~3.02 miles northeast of Cayce
  • 3 star Downtown property
  • Fitness + Health Center
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From£60
Average 3.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown - Columbia 501 Taylor St., Columbia, SC 29201 Call ~3.05 miles north of Cayce
  • Three Star Downtown property
  • Fitness + Health Center
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From£96
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Aloft Columbia Downtown 823 Lady St., Columbia, SC 29201 Call ~3.06 miles northeast of Cayce
  • Midscale Downtown property
  • Fitness + Health Center
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From£60
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih 901 Washington St., Columbia, SC 29201 Call ~3.18 miles northeast of Cayce
  • 3 star property
  • Fitness + Health Center
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From£67
Very good 4.0 /5 Read Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista : 1000 Lady St. 1000 Lady St., Columbia, SC 29201 Website Call ~3.18 miles northeast of Cayce
  • Affordable Downtown property
  • Check in time: 3:00 PM
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From£74
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Staybridge Suites Columbia An Ihg Hotel 1913 Huger St., Columbia, SC 29201 Call ~3.26 miles north of Cayce
  • Midscale Downtown property
  • Fitness + Health Center
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From£81
Very good 4.0 /5 Reviews Call BookMore Details
Moxy Columbia Downtown : 1200 Main St. 1200 Main St., Columbia, SC 29201 Call ~3.31 miles northeast of Cayce
  • 4-star property
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From£93
Average 3.0 /5 Recent Reviews Call BookMore Details
Microtel 1301 Main St., Columbia, SC 29201 Call ~3.33 miles northeast of Cayce
  • Two star Downtown property
  • Free breakfast available
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From£33
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Sheraton Columbia Downtown Hotel - Columbia 1400 Main St., Columbia, SC 29201 Call ~3.43 miles northeast of Cayce
  • High end Downtown property
  • 17 floors in hotel
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From£96
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Columbia Downtown - Columbia 1233 Washington St., Columbia, SC 29201 Call ~3.47 miles northeast of Cayce
  • Affordable Downtown hotel
  • Check-in time: 12:00 PM
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From£60
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Marriott Columbia 1200 Hampton St., Columbia, SC 29201 Call ~3.48 miles northeast of Cayce
  • High end Downtown property
  • 15 conference rooms in property
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From£70
Very good 4.0 /5 Latest Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033 Call
  • Two-star property
  • Check-in time: 15:00
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From£45
Poor 2.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone in Columbia 180 Stoneridge Dr., Columbia, SC 29210 Call ~3.54 miles north of Cayce
  • Cheap Downtown hotel
  • Check-in time: 3:00 p.m.
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From£26
Average 3.0 /5 Review Score Call BookMore Details
Hotel Trundle : 1224 Taylor St. 1224 Taylor St., Columbia, SC 29201 Call ~3.56 miles northeast of Cayce
  • Midscale Downtown property
  • Check in time: 3pm
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From£111
Very good 4.0 /5 Guest Reviews Call BookMore Details
Graduate by Hilton Columbia SC in Columbia 1619 Pendleton St., Columbia, SC 29201 Call ~3.57 miles northeast of Cayce
  • Four star Downtown hotel
  • 119 rooms in property
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From£96
Average 3.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 in Columbia 450 Gracern Rd., Columbia, SC 29210 Call ~3.57 miles north of Cayce
  • Economy property
  • 120 rooms in hotel
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From£20
Poor 2.0 /5 Latest Reviews Call BookMore Details
Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169 Call ~3.61 miles northwest of Cayce
  • Affordable Highway hotel
  • Hotel has 4 floors
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From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
TRU Columbia Greystone : 183 Stoneridge Dr. 183 Stoneridge Dr., Columbia, SC 29210 Call ~3.64 miles north of Cayce
  • Three Star Downtown property
  • Fitness + Health Center
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From£67
Average 3.0 /5 Latest Reviews Call BookMore Details
Embassy Suites Columbia - Columbia 200 Stoneridge Dr., Columbia, SC 29210 Call ~3.65 miles north of Cayce
  • Three Star Suburban hotel
  • Check-in time: 3:00 PM
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From£88
Very good 4.0 /5 Latest Reviews Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210 Call ~3.66 miles north of Cayce
  • 3 star Downtown hotel
  • 117 rooms in property
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From£60
Average 3.0 /5 Review Score Call BookMore Details
Carolina University Inn in Columbia 1615 Gervais St., Columbia, SC 29201 Call ~3.66 miles northeast of Cayce
  • Mid-scale Downtown property
  • Check-in time: 3:00 PM
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From£44
Poor 2.5 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201 Call ~3.67 miles northeast of Cayce
  • 3 star hotel
  • 5 suites in hotel
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From£60
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Hilton Garden Inn Columbia Airport : 110 Mcswain Dr. 110 Mcswain Dr., West Columbia, SC 29169 Call ~3.76 miles northwest of Cayce
  • Mid-scale Airport hotel
  • 122 rooms in property
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From£71
Very good 4.0 /5 Latest Reviews Call BookMore Details
Oyo Hotel Columbia Sc West : 114 Mcswain Dr. 114 Mcswain Dr., Columbia, SC 29169 Call ~3.86 miles northwest of Cayce
  • Midscale property
  • Check-in time: 15:00
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From£67
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Columbia in Columbia 230 Greystone Blvd., Columbia, SC 29210 Call ~3.91 miles north of Cayce
  • 3 star Downtown hotel
  • 81 suites in hotel
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From£56
Average 3.0 /5 Hotel Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington in West Columbia 122 Mathias Rd., West Columbia, SC 29169 Call ~4.07 miles northwest of Cayce
  • Midscale Highway property
  • Check in: 4:00 PM
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From£56
Average 3.0 /5 Latest Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington - West Columbia 2915 Sunset Blvd., West Columbia, SC 29169 Call ~4.18 miles northwest of Cayce
  • Affordable property
  • Hotel has 4 floors
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From£56
Very good 4.0 /5 Reviews Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210 Call ~5.07 miles north of Cayce
  • Midscale Highway property
  • Check-in time: 3:00 PM
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From£46
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Columbia 1144 Bush River Rd., Columbia, SC 29210 Call ~5.13 miles northwest of Cayce
  • Low-priced hotel
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From£45
Terrible 1.0 /5 Recent Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia 200 Zimalcrest Dr., Columbia, SC 29210 Call ~5.29 miles northwest of Cayce
  • Three Star Suburban property
  • Hotel has 64 rooms
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From£36
Average 3.0 /5 Reviews Call BookMore Details

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Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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