Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia in Cayce 3020 Charleston Highway, Cayce, SC 29033 Call
  • Two-star hotel
More Photos
From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce - Cayce 1987 Airport Blvd., Cayce, SC 29033 Call
  • Cheap property
  • 2 floors in hotel
More Photos
From£40
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033 Call
  • Two-star Airport hotel
  • Hotel has 9 suites
More Photos
From£52
Very good 4.0 /5 Latest Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott - Cayce 613 Knox Abbott Dr., Cayce, NC 29033 Call
  • 3 star hotel
  • Check-in time: 15:00
More Photos
From£55
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport in West Columbia 650 Cherokee Lane, West Columbia, SC 29169 Call ~1.52 miles west of Cayce
  • Economy Airport property
  • Hotel has 115 rooms
More Photos
From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 West Columbia Sc in West Columbia 2200 Airport Blvd., West Columbia, SC 29170 Call ~1.66 miles west of Cayce
  • Two-star property
  • 82 rooms in property
More Photos
From£45
Average 3.0 /5 Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport : 2204 Airport Blvd. 2204 Airport Blvd., West Columbia, SC 29170 Call ~1.70 miles west of Cayce
  • Low-priced Airport hotel
  • Check in time: 3:00PM
More Photos
From£49
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sleep Inn Airport : 2208 Airport Blvd. 2208 Airport Blvd., West Columbia, SC 29170 Call ~1.74 miles west of Cayce
  • Cheap Airport hotel
  • Gym / Fitness Center Available
More Photos
From£45
Very good 4.0 /5 Guest Reviews Call BookMore Details
Country Inn & Suites Columbia Airport 2245 Airport Blvd., Cayce, SC 29033 Call
  • Three Star Airport hotel
  • Check-in: 15:00
More Photos
From£49
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport in West Columbia 110 Branch Rd., West Columbia, SC 29170 Call ~1.82 miles west of Cayce
  • Inexpensive Airport property
  • Check-in time: 11:59 AM
More Photos
From£45
Poor 2.0 /5 Review Score Call BookMore Details
Clarion Inn Airport West Columbia 29169, West Columbia, SC 29169 Call ~2.17 miles north of Cayce
  • Mid-scale Airport hotel
  • 5 meeting rooms in property
More Photos
From£60
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172 Call ~2.40 miles south of Cayce
  • 3-star Airport property
  • Check-in time: 15:00
More Photos
From£60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce : 1125 Fort Congaree Trail 1125 Fort Congaree Trail, Cayce, SC 29033 Call
  • Affordable Highway property
  • Hotel has 3 suites
More Photos
From£74
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn Columbia Airport - West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website Call ~2.53 miles northwest of Cayce
  • 2-star Airport property
  • Hotel has 2 floors
More Photos
From£45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Columbia Airport : 500 Chris Dr. 500 Chris Dr., West Columbia, SC 29169 Call ~2.67 miles northwest of Cayce
  • 3-star Airport hotel
  • Hotel has 142 rooms
More Photos
From£39
Very good 4.0 /5 Read Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201 Call ~2.80 miles east of Cayce
  • Low-priced Downtown property
  • Hotel has 3 floors
More Photos
From£45
Average 3.0 /5 Review Score Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista - Columbia 511 Lady St., Columbia, SC 29201 Call ~2.83 miles northeast of Cayce
  • Midscale Downtown hotel
  • Comp. Breakfast
More Photos
From£74
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201 Call ~2.95 miles northeast of Cayce
  • 3 star Downtown hotel
  • Check-in: 4pm
More Photos
From£74
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District 822 Gervais St., Columbia, SC 29201 Call ~3.00 miles northeast of Cayce
  • 3 star Downtown property
  • Comp. Breakfast
More Photos
From£94
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Hilton Columbia Center - Columbia 924 Senate St., Columbia, SC 29201 Call ~3.01 miles northeast of Cayce
  • 4-star Downtown hotel
  • Gym is available on property
More Photos
From£76
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista - Columbia 819 Gervais St., Columbia, SC 29201 Call ~3.02 miles northeast of Cayce
  • Three Star Downtown property
  • Fitness center on property
More Photos
From£60
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown - Columbia 501 Taylor St., Columbia, SC 29201 Call ~3.05 miles north of Cayce
  • Affordable Downtown hotel
  • 3 suites in hotel
More Photos
From£97
Average 3.0 /5 Recent Reviews Call BookMore Details
Aloft Columbia Downtown : 823 Lady St. 823 Lady St., Columbia, SC 29201 Call ~3.06 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • 107 sleeping rooms in hotel
More Photos
From£60
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih : 901 Washington St. 901 Washington St., Columbia, SC 29201 Call ~3.18 miles northeast of Cayce
  • Mid-scale hotel
  • 105 rooms in hotel
More Photos
From£68
Very good 4.0 /5 Latest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista 1000 Lady St., Columbia, SC 29201 Website Call ~3.18 miles northeast of Cayce
  • 3-star Downtown property
  • 3 conference rooms in property
More Photos
From£74
Average 3.0 /5 Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel : 1913 Huger St. 1913 Huger St., Columbia, SC 29201 Call ~3.26 miles north of Cayce
  • Midscale Downtown property
  • Check in time: 3:00PM
More Photos
From£82
Very good 4.0 /5 Guest Reviews Call BookMore Details
Moxy Columbia Downtown 1200 Main St., Columbia, SC 29201 Call ~3.31 miles northeast of Cayce
  • High-end hotel
More Photos
From£94
Average 3.0 /5 Guest Reviews Call BookMore Details
Microtel in Columbia 1301 Main St., Columbia, SC 29201 Call ~3.33 miles northeast of Cayce
  • Cheap Downtown hotel
  • Check-in time: 3:00 PM
More Photos
From£34
Average 3.0 /5 Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel : 1400 Main St. 1400 Main St., Columbia, SC 29201 Call ~3.43 miles northeast of Cayce
  • Expensive Downtown property
  • 17 floors in property
More Photos
From£97
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Columbia Downtown : 1233 Washington St. 1233 Washington St., Columbia, SC 29201 Call ~3.47 miles northeast of Cayce
  • Midscale Downtown property
  • Fitness center on property
More Photos
From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
Marriott Columbia 1200 Hampton St., Columbia, SC 29201 Call ~3.48 miles northeast of Cayce
  • High-end Downtown property
  • Check-in: 4:00pm
More Photos
From£71
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia I-26 2125 Commerce Dr., Cayce, NC 29033 Call
  • Two star hotel
More Photos
From£45
Poor 2.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone in Columbia 180 Stoneridge Dr., Columbia, SC 29210 Call ~3.54 miles north of Cayce
  • Inexpensive Downtown property
  • Comp. Breakfast
More Photos
From£26
Average 3.0 /5 Guest Reviews Call BookMore Details
Hotel Trundle 1224 Taylor St., Columbia, SC 29201 Call ~3.56 miles northeast of Cayce
  • Midscale Downtown property
  • Has environment-friendly policy Read more
More Photos
From£112
Very good 4.0 /5 Reviews Call BookMore Details
Graduate by Hilton Columbia SC 1619 Pendleton St., Columbia, SC 29201 Call ~3.57 miles northeast of Cayce
  • Expensive Downtown hotel
  • Hotel has 119 rooms
More Photos
From£97
Average 3.0 /5 Review Score Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 : 450 Gracern Rd. 450 Gracern Rd., Columbia, SC 29210 Call ~3.57 miles north of Cayce
  • Economy hotel
  • 120 rooms in hotel
More Photos
From£20
Poor 2.0 /5 Latest Reviews Call BookMore Details
Hampton Inn I 26 Airport in West Columbia 1094 Chris Dr., West Columbia, SC 29169 Call ~3.61 miles northwest of Cayce
  • Affordable Highway property
  • Comp. Breakfast
More Photos
From£60
Average 3.0 /5 Hotel Reviews Call BookMore Details
TRU Columbia Greystone 183 Stoneridge Dr., Columbia, SC 29210 Call ~3.64 miles north of Cayce
  • Three Star Downtown property
  • Check-in: 15:00
More Photos
From£68
Average 3.0 /5 Guest Reviews Call BookMore Details
Embassy Suites Columbia - Columbia 200 Stoneridge Dr., Columbia, SC 29210 Call ~3.65 miles north of Cayce
  • Mid-scale Suburban property
  • Check-in: 3:00 PM
More Photos
From£89
Very good 4.0 /5 Review Score Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210 Call ~3.66 miles north of Cayce
  • Mid-scale Downtown property
  • Complimentary breakfast is offered
More Photos
From£60
Average 3.0 /5 Latest Reviews Call BookMore Details
Carolina University Inn : 1615 Gervais St. 1615 Gervais St., Columbia, SC 29201 Call ~3.66 miles northeast of Cayce
  • Three Star Downtown property
  • Access to gym on-site
More Photos
From£44
Poor 2.5 /5 Review Score Call BookMore Details
Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201 Call ~3.67 miles northeast of Cayce
  • Midscale property
  • 5 suites in hotel
More Photos
From£60
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Columbia Airport 110 Mcswain Dr., West Columbia, SC 29169 Call ~3.76 miles northwest of Cayce
  • Affordable Airport property
  • Fitness center on property
More Photos
From£71
Very good 4.0 /5 Recent Reviews Call BookMore Details
Oyo Hotel Columbia Sc West 114 Mcswain Dr., Columbia, SC 29169 Call ~3.86 miles northwest of Cayce
  • Affordable property
More Photos
From£68
Very good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210 Call ~3.91 miles north of Cayce
  • Affordable Downtown property
  • 6 meeting rooms in hotel
More Photos
From£56
Average 3.0 /5 Guest Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington : 122 Mathias Rd. 122 Mathias Rd., West Columbia, SC 29169 Call ~4.07 miles northwest of Cayce
  • Midscale Highway hotel
  • Hotel has 108 suites
More Photos
From£56
Average 3.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington 2915 Sunset Blvd., West Columbia, SC 29169 Call ~4.18 miles northwest of Cayce
  • 3-star hotel
  • 111 sleeping rooms in hotel
More Photos
From£56
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210 Call ~5.07 miles north of Cayce
  • Three Star Highway property
  • Check-in: 3:00 PM
More Photos
From£46
Very good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Columbia in Columbia 1144 Bush River Rd., Columbia, SC 29210 Call ~5.13 miles northwest of Cayce
  • Economical property
More Photos
From£45
Terrible 1.0 /5 Guest Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia : 200 Zimalcrest Dr. 200 Zimalcrest Dr., Columbia, SC 29210 Call ~5.29 miles northwest of Cayce
  • Midscale Suburban property
  • 2 floors in property
More Photos
From£37
Average 3.0 /5 Hotel Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
Back to Top
Table of Contents Top: Check Rates Cayce Hotels