Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Accommodations

Country Hearth Inn & Suites Cayce / Columbia in Cayce
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3020 Charleston Highway, Cayce, SC 29033 +1-888-389-4121
  • Cheap hotel
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From£45
Average 3.0 /5 Guest Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce : 1987 Airport Blvd.
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1987 Airport Blvd., Cayce, SC 29033 +1-888-675-2083
  • Two-star hotel
  • 2 floors in hotel
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From£40
Poor 2.0 /5 Recent Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport in Cayce
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1935 Airport Blvd., Cayce, SC 29033 +1-800-716-8490
  • Low-priced Airport hotel
  • Check in: 3PM
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From£52
Very good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott : 613 Knox Abbott Dr.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
613 Knox Abbott Dr., Cayce, NC 29033 +1-800-805-5223
  • Three Star hotel
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From£56
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
650 Cherokee Lane, West Columbia, SC 29169 +1-888-965-1860 ~1.52 miles west of Cayce
  • 2 star Airport property
  • Airport shuttle provided
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From£45
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 West Columbia Sc in West Columbia
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2200 Airport Blvd., West Columbia, SC 29170 +1-888-788-5576 ~1.66 miles west of Cayce
  • Low-priced hotel
  • Hotel has 2 floors
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From£45
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport - West Columbia
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2204 Airport Blvd., West Columbia, SC 29170 +1-888-897-9207 ~1.70 miles west of Cayce
  • Low Cost Airport hotel
  • Check-in time: 3:00PM
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From£49
Average 3.0 /5 Read Reviews Call BookMore Details
Sleep Inn Airport in West Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2208 Airport Blvd., West Columbia, SC 29170 +1-888-311-4278 ~1.74 miles west of Cayce
  • Cheap Airport property
  • 69 rooms in hotel
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From£45
Very good 4.0 /5 Guest Reviews Call BookMore Details
Country Inn & Suites Columbia Airport - Cayce
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2245 Airport Blvd., Cayce, SC 29033 +1-888-469-4795
  • Three Star Airport property
  • Free complimentary breakfast
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From£49
Very good 4.5 /5 Read Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport : 110 Branch Rd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
110 Branch Rd., West Columbia, SC 29170 +1-888-734-9421 ~1.82 miles west of Cayce
  • Two-star Airport property
  • Airport shuttle provided
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From£45
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Airport West Columbia : 29169
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
29169, West Columbia, SC 29169 +1-888-841-5292 ~2.17 miles north of Cayce
  • Mid-scale Airport property
  • 2 floors in property
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From£60
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn & Suites - West Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3020 Charleston Highway, West Columbia, SC 29172 +1-888-455-5160 ~2.40 miles south of Cayce
  • 3 star Airport hotel
  • 57 sleeping rooms in hotel
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From£60
Average 3.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Columbia Cayce : 1125 Fort Congaree Trail
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1125 Fort Congaree Trail, Cayce, SC 29033 +1-888-965-8297
  • 3-star Highway property
  • 100 sleeping rooms in hotel
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From£74
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn Columbia Airport
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2516 Augusta Rd., West Columbia, SC 29169 Website +1-888-906-6358 ~2.53 miles northwest of Cayce
  • Cheap Airport property
  • 82 sleeping rooms in hotel
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From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Clarion Inn Columbia Airport : 500 Chris Dr.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
500 Chris Dr., West Columbia, SC 29169 +1-888-749-6785 ~2.67 miles northwest of Cayce
  • Mid-scale Airport property
  • 2 floors in property
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From£39
Very good 4.0 /5 Guest Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
621 South Assembly St., Columbia, SC 29201 +1-888-878-9982 ~2.80 miles east of Cayce
  • Two star Downtown property
  • Check-in time: 3p.m.
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From£45
Average 3.0 /5 Review Score Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista - Columbia
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
511 Lady St., Columbia, SC 29201 +1-888-389-4485 ~2.83 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Free complimentary breakfast
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From£74
Very good 4.0 /5 Recent Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
630 Assembly St., Columbia, SC 29201 +1-888-389-4121 ~2.95 miles northeast of Cayce
  • Three Star Downtown property
  • Check in: 4pm
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From£74
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Columbia/Downtown/The Vista - Columbia
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
819 Gervais St., Columbia, SC 29201 +1-888-675-2083 ~2.98 miles northeast of Cayce
  • 3-star Downtown hotel
  • Hotel has an eco-friendly policy Read more
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From£82
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District - Columbia
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
822 Gervais St., Columbia, SC 29201 +1-800-716-8490 ~3.00 miles northeast of Cayce
  • 3 star Downtown property
  • Check in: 3:00PM
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From£94
Very good 4.5 /5 Latest Reviews Call BookMore Details
Hilton Columbia Center
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
924 Senate St., Columbia, SC 29201 +1-800-805-5223 ~3.01 miles northeast of Cayce
  • 4-star Downtown hotel
  • 8 floors in property
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From£76
Very good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown : 501 Taylor St.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
501 Taylor St., Columbia, SC 29201 +1-888-965-1860 ~3.05 miles north of Cayce
  • Affordable Downtown hotel
  • Free comp. breakfast
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From£97
Average 3.0 /5 Recent Reviews Call BookMore Details
Aloft Columbia Downtown in Columbia
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
823 Lady St., Columbia, SC 29201 +1-888-788-5576 ~3.06 miles northeast of Cayce
  • Affordable Downtown hotel
  • 5 floors in property
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From£60
Very good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih in Columbia
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
901 Washington St., Columbia, SC 29201 +1-888-897-9207 ~3.18 miles northeast of Cayce
  • Mid-scale property
  • Check in time: 15:00
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From£68
Very good 4.0 /5 Guest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista - Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1000 Lady St., Columbia, SC 29201 Website +1-888-311-4278 ~3.18 miles northeast of Cayce
  • 3-star Downtown property
  • Check in: 3:00 PM
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From£74
Average 3.0 /5 Hotel Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel - Columbia
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1913 Huger St., Columbia, SC 29201 +1-888-469-4795 ~3.26 miles north of Cayce
  • 3 star Downtown property
  • Hotel has 5 floors
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From£82
Very good 4.0 /5 Guest Reviews Call BookMore Details
Moxy Columbia Downtown : 1200 Main St.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1200 Main St., Columbia, SC 29201 +1-888-734-9421 ~3.31 miles northeast of Cayce
  • High-end property
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From£94
Average 3.0 /5 Read Reviews Call BookMore Details
Microtel
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1301 Main St., Columbia, SC 29201 +1-888-841-5292 ~3.33 miles northeast of Cayce
  • Low Cost Downtown property
  • Hotel has 60 rooms
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From£34
Average 3.0 /5 Read Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1400 Main St., Columbia, SC 29201 +1-888-455-5160 ~3.43 miles northeast of Cayce
  • Four-star Downtown hotel
  • Fitness center on property
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From£97
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Columbia Downtown in Columbia
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1233 Washington St., Columbia, SC 29201 +1-888-965-8297 ~3.47 miles northeast of Cayce
  • Mid-scale Downtown property
  • Check in time: 12:00 PM
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From£60
Average 3.0 /5 Reviews Call BookMore Details
Marriott Columbia : 1200 Hampton St.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1200 Hampton St., Columbia, SC 29201 +1-888-906-6358 ~3.48 miles northeast of Cayce
  • Four star Downtown hotel
  • 15 suites in hotel
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From£71
Very good 4.0 /5 Latest Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2125 Commerce Dr., Cayce, NC 29033 +1-888-749-6785
  • Low priced property
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From£45
Poor 2.0 /5 Recent Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
180 Stoneridge Dr., Columbia, SC 29210 +1-888-878-9982 ~3.54 miles north of Cayce
  • 2-star Downtown hotel
  • Hotel has 3 floors
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From£26
Average 3.0 /5 Latest Reviews Call BookMore Details
Hotel Trundle
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1224 Taylor St., Columbia, SC 29201 +1-888-389-4485 ~3.56 miles northeast of Cayce
  • 3 star Downtown hotel
  • Check in time: 3pm
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From£112
Very good 4.0 /5 Guest Reviews Call BookMore Details
Graduate by Hilton Columbia SC - Columbia
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1619 Pendleton St., Columbia, SC 29201 +1-888-389-4121 ~3.57 miles northeast of Cayce
  • High-end Downtown property
  • Complimentary breakfast is offered
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From£97
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
450 Gracern Rd., Columbia, SC 29210 +1-888-675-2083 ~3.57 miles north of Cayce
  • Cheap hotel
  • Complimentary breakfast is offered
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From£20
Poor 2.0 /5 Review Score Call BookMore Details
Hampton Inn I 26 Airport
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1094 Chris Dr., West Columbia, SC 29169 +1-800-716-8490 ~3.61 miles northwest of Cayce
  • Affordable Highway property
  • 120 rooms in hotel
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From£60
Average 3.0 /5 Review Score Call BookMore Details
TRU Columbia Greystone in Columbia
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
183 Stoneridge Dr., Columbia, SC 29210 +1-800-805-5223 ~3.64 miles north of Cayce
  • Three Star Downtown property
  • Hotel has 117 rooms
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From£68
Average 3.0 /5 Hotel Reviews Call BookMore Details
Embassy Suites Columbia in Columbia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
200 Stoneridge Dr., Columbia, SC 29210 +1-888-965-1860 ~3.65 miles north of Cayce
  • 3 star Suburban hotel
  • 214 suites in hotel
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From£89
Very good 4.0 /5 Hotel Reviews Call BookMore Details
TRU by Hilton Columbia Greystone in Columbia
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
185 Stoneridge Dr., Columbia, SC 29210 +1-888-788-5576 ~3.66 miles north of Cayce
  • 3-star Downtown property
  • Complimentary breakfast is offered
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From£60
Average 3.0 /5 Latest Reviews Call BookMore Details
Carolina University Inn
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1615 Gervais St., Columbia, SC 29201 +1-888-897-9207 ~3.66 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Check in: 3:00 PM
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From£44
Poor 2.5 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown : 1609 Gervais St.
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1609 Gervais St., Columbia, SC 29201 +1-888-311-4278 ~3.67 miles northeast of Cayce
  • Three Star hotel
  • 100 rooms in hotel
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From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
110 Mcswain Dr., West Columbia, SC 29169 +1-888-469-4795 ~3.76 miles northwest of Cayce
  • Affordable Airport property
  • Gym is available on property
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From£71
Very good 4.0 /5 Latest Reviews Call BookMore Details
Oyo Hotel Columbia Sc West : 114 Mcswain Dr.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
114 Mcswain Dr., Columbia, SC 29169 +1-888-734-9421 ~3.86 miles northwest of Cayce
  • Affordable hotel
  • Check in time: 15:00
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From£68
Very good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Columbia - Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
230 Greystone Blvd., Columbia, SC 29210 +1-888-841-5292 ~3.91 miles north of Cayce
  • 3-star Downtown hotel
  • 81 sleeping rooms in hotel
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From£56
Average 3.0 /5 Recent Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
122 Mathias Rd., West Columbia, SC 29169 +1-888-455-5160 ~4.07 miles northwest of Cayce
  • 3 star Highway hotel
  • Check in time: 4:00 PM
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From£56
Average 3.0 /5 Recent Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington - West Columbia
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2915 Sunset Blvd., West Columbia, SC 29169 +1-888-965-8297 ~4.18 miles northwest of Cayce
  • Mid-scale property
  • Check-in: 3:00pm
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From£56
Very good 4.0 /5 Guest Reviews Call BookMore Details
Comfort Inn Columbia - Columbia
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
911 Bush River Rd., Columbia, SC 29210 +1-888-906-6358 ~5.07 miles north of Cayce
  • Mid-scale Highway hotel
  • Check-in time: 3:00 PM
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From£46
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Columbia
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1144 Bush River Rd., Columbia, SC 29210 +1-888-749-6785 ~5.13 miles northwest of Cayce
  • Economy hotel
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From£45
Terrible 1.0 /5 Read Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia in Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
200 Zimalcrest Dr., Columbia, SC 29210 +1-888-878-9982 ~5.29 miles northwest of Cayce
  • 3-star Suburban hotel
  • 64 suites in property
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From£37
Average 3.0 /5 Review Score Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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