Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia : 3020 Charleston Highway 3020 Charleston Highway, Cayce, SC 29033 Call
  • Two-star property
More Photos
From£53 total
Average 3.0 /5 Read Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce - Cayce 1987 Airport Blvd., Cayce, SC 29033 Call
  • Economical property
  • 2 floors in hotel
More Photos
From£46 total
Poor 2.0 /5 Hotel Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport in Cayce 1935 Airport Blvd., Cayce, SC 29033 Call
  • Cheap Airport hotel
  • 51 rooms in hotel
More Photos
From£61 total
Very good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott - Cayce 613 Knox Abbott Dr., Cayce, NC 29033 Call
  • Mid-scale property
More Photos
From£65 total
Average 3.0 /5 Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport 650 Cherokee Lane, West Columbia, SC 29169 Call ~1.52 miles west of Cayce
  • Cheap Airport property
  • Shuttle to airport available
More Photos
From£53 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 West Columbia Sc in West Columbia 2200 Airport Blvd., West Columbia, SC 29170 Call ~1.66 miles west of Cayce
  • Cheap hotel
  • Hotel has 2 floors
More Photos
From£53 total
Average 3.0 /5 Review Score Call BookMore Details
Red Roof Inn Columbia, SC Airport 2204 Airport Blvd., West Columbia, SC 29170 Call ~1.70 miles west of Cayce
  • Two-star Airport property
  • Hotel has 64 rooms
More Photos
From£57 total
Average 3.0 /5 Read Reviews Call BookMore Details
Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170 Call ~1.74 miles west of Cayce
  • Low priced Airport hotel
  • 5 floors in property
More Photos
From£53 total
Very good 4.0 /5 Review Score Call BookMore Details
Country Inn & Suites Columbia Airport 2245 Airport Blvd., Cayce, SC 29033 Call
  • Affordable Airport hotel
  • Hotel has 64 rooms
More Photos
From£57 total
Very good 4.5 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport 110 Branch Rd., West Columbia, SC 29170 Call ~1.82 miles west of Cayce
  • Cheap Airport hotel
  • Free breakfast
More Photos
From£53 total
Poor 2.0 /5 Read Reviews Call BookMore Details
Clarion Inn Airport West Columbia - West Columbia 29169, West Columbia, SC 29169 Call ~2.17 miles north of Cayce
  • Affordable Airport property
  • Hotel has 2 floors
More Photos
From£70 total
Average 3.0 /5 Reviews Call BookMore Details
Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172 Call ~2.40 miles south of Cayce
  • Affordable Airport hotel
  • Check-in time: 15:00
More Photos
From£70 total
Average 3.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033 Call
  • Midscale Highway hotel
  • Fitness / Gym is on-site
More Photos
From£87 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Columbia Airport in West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website Call ~2.53 miles northwest of Cayce
  • Low Cost Airport property
  • 82 sleeping rooms in hotel
More Photos
From£53 total
Average 3.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Columbia Downtown : 400 Gervais St. 400 Gervais St., Columbia, SC 29214 Call ~2.67 miles northeast of Cayce
  • 3-star property
More Photos
From£70 total
Average 3.0 /5 Read Reviews Call BookMore Details
TRU by Hilton Columbia Downtown : 400a Gervais St. 400a Gervais St., Columbia, SC 29214 Call ~2.67 miles northeast of Cayce
  • Mid-scale hotel
  • Check-in: 3:00PM
More Photos
From£70 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Columbia Airport in West Columbia 500 Chris Dr., West Columbia, SC 29169 Call ~2.67 miles northwest of Cayce
  • Three Star Airport hotel
  • Fitness + Health Center
More Photos
From£46 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201 Call ~2.80 miles east of Cayce
  • Two star Downtown property
  • Check-in time: 3p.m.
More Photos
From£53 total
Average 3.0 /5 Latest Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista 511 Lady St., Columbia, SC 29201 Call ~2.83 miles northeast of Cayce
  • 3 star Downtown hotel
  • Gym / Fitness Center Available
More Photos
From£87 total
Very good 4.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201 Call ~2.95 miles northeast of Cayce
  • Mid-scale Downtown property
  • Airport shuttle provided
More Photos
From£87 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District in Columbia 822 Gervais St., Columbia, SC 29201 Call ~3.00 miles northeast of Cayce
  • 3 star Downtown hotel
  • Access to gym on-site
More Photos
From£110 total
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Hilton Columbia Center - Columbia 924 Senate St., Columbia, SC 29201 Call ~3.01 miles northeast of Cayce
  • 4 star Downtown property
  • Hotel has 222 rooms
More Photos
From£89 total
Very good 4.0 /5 Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista in Columbia 819 Gervais St., Columbia, SC 29201 Call ~3.02 miles northeast of Cayce
  • Three Star Downtown property
  • Gym / Fitness Center Available
More Photos
From£70 total
Average 3.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown in Columbia 501 Taylor St., Columbia, SC 29201 Call ~3.05 miles north of Cayce
  • Mid-scale Downtown property
  • Gym is available on property
More Photos
From£114 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Aloft by Marriott Columbia Downtown in Columbia 823 Lady St., Columbia, SC 29201 Call ~3.06 miles northeast of Cayce
  • Midscale Downtown property
  • 107 rooms in property
More Photos
From£70 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih : 901 Washington St. 901 Washington St., Columbia, SC 29201 Call ~3.18 miles northeast of Cayce
  • 3-star hotel
  • 105 rooms in property
More Photos
From£79 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista in Columbia 1000 Lady St., Columbia, SC 29201 Website Call ~3.18 miles northeast of Cayce
  • Midscale Downtown property
  • Fitness + Health Center
More Photos
From£87 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel in Columbia 1913 Huger St., Columbia, SC 29201 Call ~3.26 miles north of Cayce
  • Three Star Downtown hotel
  • Hotel has 93 suites
More Photos
From£96 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Moxy Columbia : 1200 Main St. 1200 Main St., Columbia, SC 29201 Call ~3.31 miles northeast of Cayce
  • Midscale Downtown property
  • Hotel has 128 rooms
More Photos
From£70 total
Average 3.0 /5 Read Reviews Call BookMore Details
Microtel 1301 Main St., Columbia, SC 29201 Call ~3.33 miles northeast of Cayce
  • Cheap Downtown property
  • Hotel has 5 floors
More Photos
From£39 total
Average 3.0 /5 Review Score Call BookMore Details
Sheraton Columbia Downtown Hotel : 1400 Main St. 1400 Main St., Columbia, SC 29201 Call ~3.43 miles northeast of Cayce
  • Expensive Downtown property
  • Check-in time: 3:00pm
More Photos
From£114 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Columbia Downtown - Columbia 1233 Washington St., Columbia, SC 29201 Call ~3.47 miles northeast of Cayce
  • Three Star Downtown property
  • Fitness center on property
More Photos
From£70 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Marriott Columbia 1200 Hampton St., Columbia, SC 29201 Call ~3.48 miles northeast of Cayce
  • Four star Downtown hotel
  • 300 rooms in property
More Photos
From£83 total
Very good 4.0 /5 Guest Reviews Call BookMore Details
Masters Inn Columbia I-26 2125 Commerce Dr., Cayce, NC 29033 Call
  • Low-priced property
  • Check in time: 15:00
More Photos
From£53 total
Poor 2.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone in Columbia 180 Stoneridge Dr., Columbia, SC 29210 Call ~3.54 miles north of Cayce
  • Two-star Downtown hotel
  • 72 rooms in property
More Photos
From£30 total
Average 3.0 /5 Reviews Call BookMore Details
Hotel Trundle - Columbia 1224 Taylor St., Columbia, SC 29201 Call ~3.56 miles northeast of Cayce
  • Affordable Downtown property
  • Hotel has 7 suites
More Photos
From£131 total
Very good 4.0 /5 Recent Reviews Call BookMore Details
Graduate by Hilton Columbia SC in Columbia 1619 Pendleton St., Columbia, SC 29201 Call ~3.57 miles northeast of Cayce
  • High end Downtown hotel
  • Gym is available on property
More Photos
From£114 total
Average 3.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 : 450 Gracern Rd. 450 Gracern Rd., Columbia, SC 29210 Call ~3.57 miles north of Cayce
  • Low-priced property
  • Hotel has 120 rooms
More Photos
From£23 total
Poor 2.0 /5 Review Score Call BookMore Details
Hampton Inn I 26 Airport : 1094 Chris Dr. 1094 Chris Dr., West Columbia, SC 29169 Call ~3.61 miles northwest of Cayce
  • 3 star Highway property
  • Free comp. breakfast
More Photos
From£70 total
Average 3.0 /5 Hotel Reviews Call BookMore Details
Embassy Suites Columbia 200 Stoneridge Dr., Columbia, SC 29210 Call ~3.65 miles north of Cayce
  • Mid-scale Suburban property
  • 214 rooms in hotel
More Photos
From£104 total
Very good 4.0 /5 Review Score Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210 Call ~3.66 miles north of Cayce
  • Affordable Downtown property
  • Hotel has 117 rooms
More Photos
From£70 total
Average 3.0 /5 Recent Reviews Call BookMore Details
Carolina University Inn : 1615 Gervais St. 1615 Gervais St., Columbia, SC 29201 Call ~3.66 miles northeast of Cayce
  • Three Star Downtown property
  • Has environment-friendly policy Learn more
More Photos
From£52 total
Poor 2.5 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201 Call ~3.67 miles northeast of Cayce
  • 3-star property
  • Check-in time: 15:00
More Photos
From£70 total
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport - West Columbia 110 Mcswain Dr., West Columbia, SC 29169 Call ~3.76 miles northwest of Cayce
  • Three Star Airport property
  • Hotel has 5 meeting rooms
More Photos
From£84 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Oyo Hotel Columbia Sc West : 114 Mcswain Dr. 114 Mcswain Dr., Columbia, SC 29169 Call ~3.86 miles northwest of Cayce
  • 3 star hotel
  • Check-in time: 15:00
More Photos
From£79 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Homewood Suites by Hilton Columbia : 230 Greystone Blvd. 230 Greystone Blvd., Columbia, SC 29210 Call ~3.91 miles north of Cayce
  • Affordable Downtown hotel
  • Check in: 3:00pm
More Photos
From£66 total
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington 122 Mathias Rd., West Columbia, SC 29169 Call ~4.07 miles northwest of Cayce
  • Affordable Highway property
  • Check-in: 4:00 PM
More Photos
From£66 total
Average 3.0 /5 Guest Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington 2915 Sunset Blvd., West Columbia, SC 29169 Call ~4.18 miles northwest of Cayce
  • 3 star hotel
  • Hotel has 4 floors
More Photos
From£66 total
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Comfort Inn Columbia 911 Bush River Rd., Columbia, SC 29210 Call ~5.07 miles north of Cayce
  • Affordable Highway property
  • Complimentary breakfast is offered
More Photos
From£54 total
Very good 4.0 /5 Read Reviews Call BookMore Details
Days Inn by Wyndham Columbia 1144 Bush River Rd., Columbia, SC 29210 Call ~5.13 miles northwest of Cayce
  • 2-star property
More Photos
From£53 total
Terrible 1.0 /5 Guest Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
Back to Top
Table of Contents Top: Check Rates Cayce Hotels