Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels, Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia in Cayce 3020 Charleston Highway, Cayce, SC 29033 Call
  • Low priced property
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce 1987 Airport Blvd., Cayce, SC 29033 Call
  • Low priced hotel
  • Hotel has 2 floors
From£39
Poor 2.0 /5 Read Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport in Cayce 1935 Airport Blvd., Cayce, SC 29033 Call
  • Economical Airport hotel
  • Free breakfast available
From£50
Very good 4.0 /5 Guest Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott in Cayce 613 Knox Abbott Dr., Cayce, NC 29033 Call
  • 3-star property
  • Check in time: 15:00
From£54
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport : 650 Cherokee Lane 650 Cherokee Lane, West Columbia, SC 29169 Call ~1.52 miles west of Cayce
  • Low-priced Airport property
  • Fitness + Health Center
From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170 Call ~1.66 miles west of Cayce
  • Low Cost property
  • Check-in: 3:00 PM
From£44
Average 3.0 /5 Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport - West Columbia 2204 Airport Blvd., West Columbia, SC 29170 Call ~1.70 miles west of Cayce
  • Two-star Airport property
  • 64 rooms in property
From£47
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170 Call ~1.74 miles west of Cayce
  • Economy Airport hotel
  • Hotel has 5 floors
From£44
Very good 4.0 /5 Recent Reviews Call BookMore Details
Country Inn & Suites Columbia Airport 2245 Airport Blvd., Cayce, SC 29033 Call
  • Affordable Airport hotel
  • 3 floors in hotel
From£47
Very good 4.5 /5 Review Score Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport - West Columbia 110 Branch Rd., West Columbia, SC 29170 Call ~1.82 miles west of Cayce
  • Economical Airport property
  • Check-in time: 11:59 AM
Clarion Inn Airport West Columbia 29169, West Columbia, SC 29169 Call ~2.17 miles north of Cayce
  • Affordable Airport hotel
  • Check in time: 3:00pm
From£59
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites - West Columbia 3020 Charleston Highway, West Columbia, SC 29172 Call ~2.40 miles south of Cayce
  • 3 star Airport property
  • 57 rooms in hotel
From£59
Average 3.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033 Call
  • Midscale Highway property
  • Hotel has 100 rooms
From£73
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Columbia Airport : 2516 Augusta Rd. 2516 Augusta Rd., West Columbia, SC 29169 Website Call ~2.53 miles northwest of Cayce
  • Cheap Airport hotel
  • Check in: 3:00
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
Clarion Inn Columbia Airport 500 Chris Dr., West Columbia, SC 29169 Call ~2.67 miles northwest of Cayce
  • Midscale Airport property
  • Fitness center on property
From£38
Very good 4.0 /5 Review Score Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201 Call ~2.80 miles east of Cayce
  • Low priced Downtown property
  • Free comp. breakfast
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista in Columbia 511 Lady St., Columbia, SC 29201 Call ~2.83 miles northeast of Cayce
  • 3-star Downtown hotel
  • Hotel has 132 suites
From£73
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC in Columbia 630 Assembly St., Columbia, SC 29201 Call ~2.95 miles northeast of Cayce
  • Three Star Downtown property
  • 189 rooms in hotel
From£73
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District in Columbia 822 Gervais St., Columbia, SC 29201 Call ~3.00 miles northeast of Cayce
  • 3-star Downtown property
  • Gym is available on property
From£92
Very good 4.5 /5 Read Reviews Call BookMore Details
Hilton Columbia Center 924 Senate St., Columbia, SC 29201 Call ~3.01 miles northeast of Cayce
  • Expensive Downtown hotel
  • Hotel has 222 rooms
From£74
Very good 4.0 /5 Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista in Columbia 819 Gervais St., Columbia, SC 29201 Call ~3.02 miles northeast of Cayce
  • Affordable Downtown hotel
  • Check-in: 3:00 PM
From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201 Call ~3.05 miles north of Cayce
  • Affordable Downtown property
  • Check-in: 3:00
From£95
Average 3.0 /5 Hotel Reviews Call BookMore Details
Aloft Columbia Downtown 823 Lady St., Columbia, SC 29201 Call ~3.06 miles northeast of Cayce
  • Three Star Downtown hotel
  • 5 floors in property
From£59
Very good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih : 901 Washington St. 901 Washington St., Columbia, SC 29201 Call ~3.18 miles northeast of Cayce
  • Affordable property
  • Fitness / Gym is on-site
From£66
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista 1000 Lady St., Columbia, SC 29201 Website Call ~3.18 miles northeast of Cayce
  • 3 star Downtown property
  • Hotel has 3 meeting rooms
From£73
Average 3.0 /5 Hotel Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel : 1913 Huger St. 1913 Huger St., Columbia, SC 29201 Call ~3.26 miles north of Cayce
  • 3-star Downtown hotel
  • Hotel has 93 suites
From£80
Very good 4.0 /5 Read Reviews Call BookMore Details
Moxy Columbia Downtown : 1200 Main St. 1200 Main St., Columbia, SC 29201 Call ~3.31 miles northeast of Cayce
  • High-end hotel
From£92
Average 3.0 /5 Guest Reviews Call BookMore Details
Microtel - Columbia 1301 Main St., Columbia, SC 29201 Call ~3.33 miles northeast of Cayce
  • Low-priced Downtown property
  • Hotel has 60 rooms
From£33
Average 3.0 /5 Latest Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel - Columbia 1400 Main St., Columbia, SC 29201 Call ~3.43 miles northeast of Cayce
  • 4 star Downtown hotel
  • Hotel has 14 suites
From£95
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Columbia Downtown 1233 Washington St., Columbia, SC 29201 Call ~3.47 miles northeast of Cayce
  • Three Star Downtown property
  • Hotel has an eco-friendly policy Read more
From£59
Average 3.0 /5 Recent Reviews Call BookMore Details
Marriott Columbia in Columbia 1200 Hampton St., Columbia, SC 29201 Call ~3.48 miles northeast of Cayce
  • 4 star Downtown hotel
  • Access to gym on-site
From£69
Very good 4.0 /5 Review Score Call BookMore Details
Masters Inn Columbia I-26 2125 Commerce Dr., Cayce, NC 29033 Call
  • Two star property
  • Check-in time: 15:00
Extended Stay America Suites Columbia Greystone 180 Stoneridge Dr., Columbia, SC 29210 Call ~3.54 miles north of Cayce
  • Low Cost Downtown property
  • 72 rooms in hotel
From£25
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel Trundle 1224 Taylor St., Columbia, SC 29201 Call ~3.56 miles northeast of Cayce
  • Affordable Downtown property
  • Check in: 3pm
From£109
Very good 4.0 /5 Review Score Call BookMore Details
Graduate by Hilton Columbia SC in Columbia 1619 Pendleton St., Columbia, SC 29201 Call ~3.57 miles northeast of Cayce
  • Four star Downtown property
  • Hotel has 3 floors
From£95
Average 3.0 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 : 450 Gracern Rd. 450 Gracern Rd., Columbia, SC 29210 Call ~3.57 miles north of Cayce
  • Low priced hotel
  • 120 sleeping rooms in hotel
From£19
Poor 2.0 /5 Read Reviews Call BookMore Details
Hampton Inn I 26 Airport in West Columbia 1094 Chris Dr., West Columbia, SC 29169 Call ~3.61 miles northwest of Cayce
  • Affordable Highway hotel
  • Check in: 3:00PM
From£59
Average 3.0 /5 Recent Reviews Call BookMore Details
TRU Columbia Greystone 183 Stoneridge Dr., Columbia, SC 29210 Call ~3.64 miles north of Cayce
  • 3 star Downtown property
  • Check-in: 15:00
From£66
Average 3.0 /5 Reviews Call BookMore Details
Embassy Suites Columbia in Columbia 200 Stoneridge Dr., Columbia, SC 29210 Call ~3.65 miles north of Cayce
  • 3-star Suburban hotel
  • 214 suites in property
From£87
Very good 4.0 /5 Reviews Call BookMore Details
TRU by Hilton Columbia Greystone - Columbia 185 Stoneridge Dr., Columbia, SC 29210 Call ~3.66 miles north of Cayce
  • 3-star Downtown hotel
  • 4 floors in hotel
From£59
Average 3.0 /5 Read Reviews Call BookMore Details
Carolina University Inn : 1615 Gervais St. 1615 Gervais St., Columbia, SC 29201 Call ~3.66 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • 89 sleeping rooms in hotel
Home2 Suites by Hilton Columbia Downtown - Columbia 1609 Gervais St., Columbia, SC 29201 Call ~3.67 miles northeast of Cayce
  • Three Star property
  • Check-in: 15:00
From£59
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Columbia Airport - West Columbia 110 Mcswain Dr., West Columbia, SC 29169 Call ~3.76 miles northwest of Cayce
  • Three Star Airport hotel
  • Fitness center on property
From£70
Very good 4.0 /5 Reviews Call BookMore Details
Oyo Hotel Columbia Sc West 114 Mcswain Dr., Columbia, SC 29169 Call ~3.86 miles northwest of Cayce
  • 3 star property
  • 40 rooms in property
From£66
Very good 4.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210 Call ~3.91 miles north of Cayce
  • Affordable Downtown hotel
  • 5 floors in property
From£55
Average 3.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington 122 Mathias Rd., West Columbia, SC 29169 Call ~4.07 miles northwest of Cayce
  • Three Star Highway property
  • Free complimentary breakfast
From£55
Average 3.0 /5 Review Score Call BookMore Details
Towneplace Suites Columbia West / Lexington - West Columbia 2915 Sunset Blvd., West Columbia, SC 29169 Call ~4.18 miles northwest of Cayce
  • Mid-scale property
  • Fitness + Health Center
From£55
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia - Columbia 911 Bush River Rd., Columbia, SC 29210 Call ~5.07 miles north of Cayce
  • 3 star Highway hotel
  • Hotel has 3 floors
From£45
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Columbia 1144 Bush River Rd., Columbia, SC 29210 Call ~5.13 miles northwest of Cayce
  • Inexpensive hotel
From£44
Terrible 1.0 /5 Read Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia - Columbia 200 Zimalcrest Dr., Columbia, SC 29210 Call ~5.29 miles northwest of Cayce
  • 3-star Suburban property
  • Complimentary breakfast is offered
From£36
Average 3.0 /5 Latest Reviews Call BookMore Details

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Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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