Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Accommodations

Country Hearth Inn & Suites Cayce / Columbia in Cayce
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
3020 Charleston Highway, Cayce, SC 29033 +1-888-389-4121
  • Low-priced property
More Photos
From£45
Average 3.0 /5 Read Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
1987 Airport Blvd., Cayce, SC 29033 +1-888-675-2083
  • 2-star hotel
  • 117 sleeping rooms in hotel
More Photos
From£40
Poor 2.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Inn & Suites Cayce I-26 Airport
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1935 Airport Blvd., Cayce, SC 29033 +1-800-716-8490
  • 2-star Airport property
  • 9 suites in property
More Photos
From£52
Very good 4.0 /5 Read Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
613 Knox Abbott Dr., Cayce, NC 29033 +1-800-805-5223
  • Mid-scale hotel
More Photos
From£56
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 West Columbia Sc Airport in West Columbia
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
650 Cherokee Lane, West Columbia, SC 29169 +1-888-965-1860 ~1.52 miles west of Cayce
  • Low-priced Airport property
  • 115 rooms in property
More Photos
From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
Motel 6 West Columbia Sc
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2200 Airport Blvd., West Columbia, SC 29170 +1-888-788-5576 ~1.66 miles west of Cayce
  • Economy property
  • Check in time: 3:00 PM
More Photos
From£45
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport in West Columbia
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
2204 Airport Blvd., West Columbia, SC 29170 +1-888-897-9207 ~1.70 miles west of Cayce
  • Two star Airport hotel
  • Check-in time: 3:00PM
More Photos
From£49
Average 3.0 /5 Latest Reviews Call BookMore Details
Sleep Inn Airport in West Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
2208 Airport Blvd., West Columbia, SC 29170 +1-888-311-4278 ~1.74 miles west of Cayce
  • Economy Airport hotel
  • Comp. Breakfast
More Photos
From£45
Very good 4.0 /5 Review Score Call BookMore Details
Country Inn & Suites Columbia Airport : 2245 Airport Blvd.
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
2245 Airport Blvd., Cayce, SC 29033 +1-888-469-4795
  • Mid-scale Airport hotel
  • Free complimentary breakfast
More Photos
From£49
Very good 4.5 /5 Recent Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport : 110 Branch Rd.
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
110 Branch Rd., West Columbia, SC 29170 +1-888-734-9421 ~1.82 miles west of Cayce
  • Low priced Airport property
  • Airport shuttle available
More Photos
From£45
Poor 2.0 /5 Review Score Call BookMore Details
Clarion Inn Airport West Columbia in West Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
29169, West Columbia, SC 29169 +1-888-841-5292 ~2.17 miles north of Cayce
  • 3 star Airport hotel
  • 142 sleeping rooms in hotel
More Photos
From£60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites in West Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
3020 Charleston Highway, West Columbia, SC 29172 +1-888-455-5160 ~2.40 miles south of Cayce
  • Mid-scale Airport hotel
  • Check in time: 15:00
More Photos
From£60
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1125 Fort Congaree Trail, Cayce, SC 29033 +1-888-965-8297
  • 3 star Highway hotel
  • Access to gym on-site
More Photos
From£75
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Columbia Airport - West Columbia
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
2516 Augusta Rd., West Columbia, SC 29169 Website +1-888-906-6358 ~2.53 miles northwest of Cayce
  • Cheap Airport hotel
  • Check in time: 3:00
More Photos
From£45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn Columbia Airport - West Columbia
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
500 Chris Dr., West Columbia, SC 29169 +1-888-749-6785 ~2.67 miles northwest of Cayce
  • 3 star Airport property
  • Access to gym on-site
More Photos
From£39
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection - Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
621 South Assembly St., Columbia, SC 29201 +1-888-878-9982 ~2.80 miles east of Cayce
  • Low-priced Downtown hotel
  • Free breakfast
More Photos
From£45
Average 3.0 /5 Recent Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista - Columbia
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
511 Lady St., Columbia, SC 29201 +1-888-389-4485 ~2.83 miles northeast of Cayce
  • 3-star Downtown property
  • Check-in time: 3:00 PM
More Photos
From£75
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
630 Assembly St., Columbia, SC 29201 +1-888-389-4121 ~2.95 miles northeast of Cayce
  • 3 star Downtown property
  • 189 sleeping rooms in hotel
More Photos
From£75
Very good 4.0 /5 Reviews Call BookMore Details
Hyatt Place Columbia/Downtown/The Vista
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
819 Gervais St., Columbia, SC 29201 +1-888-675-2083 ~2.98 miles northeast of Cayce
  • Affordable Downtown property
  • Free complimentary breakfast
More Photos
From£82
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District - Columbia
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
822 Gervais St., Columbia, SC 29201 +1-800-716-8490 ~3.00 miles northeast of Cayce
  • 3 star Downtown property
  • Check in: 3:00PM
More Photos
From£95
Very good 4.5 /5 Review Score Call BookMore Details
Hilton Columbia Center : 924 Senate St.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
924 Senate St., Columbia, SC 29201 +1-800-805-5223 ~3.01 miles northeast of Cayce
  • 4-star Downtown property
  • 8 meeting rooms in property
More Photos
From£76
Very good 4.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
501 Taylor St., Columbia, SC 29201 +1-888-965-1860 ~3.05 miles north of Cayce
  • Midscale Downtown property
  • Check-in time: 3:00
More Photos
From£98
Average 3.0 /5 Guest Reviews Call BookMore Details
Aloft Columbia Downtown : 823 Lady St.
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
823 Lady St., Columbia, SC 29201 +1-888-788-5576 ~3.06 miles northeast of Cayce
  • Three Star Downtown hotel
  • 5 floors in property
More Photos
From£60
Very good 4.0 /5 Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih : 901 Washington St.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
901 Washington St., Columbia, SC 29201 +1-888-897-9207 ~3.18 miles northeast of Cayce
  • Three Star property
  • 105 sleeping rooms in hotel
More Photos
From£68
Very good 4.0 /5 Latest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista - Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1000 Lady St., Columbia, SC 29201 Website +1-888-311-4278 ~3.18 miles northeast of Cayce
  • Affordable Downtown hotel
  • 3 conference rooms in property
More Photos
From£75
Average 3.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1913 Huger St., Columbia, SC 29201 +1-888-469-4795 ~3.26 miles north of Cayce
  • 3 star Downtown property
  • 5 floors in property
More Photos
From£82
Very good 4.0 /5 Review Score Call BookMore Details
Moxy Columbia Downtown
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1200 Main St., Columbia, SC 29201 +1-888-734-9421 ~3.31 miles northeast of Cayce
  • Expensive property
More Photos
From£95
Average 3.0 /5 Guest Reviews Call BookMore Details
Microtel : 1301 Main St.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1301 Main St., Columbia, SC 29201 +1-888-841-5292 ~3.33 miles northeast of Cayce
  • Two star Downtown hotel
  • Check-in time: 3:00 PM
More Photos
From£34
Average 3.0 /5 Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel in Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
1400 Main St., Columbia, SC 29201 +1-888-455-5160 ~3.43 miles northeast of Cayce
  • High-end Downtown property
  • Check-in time: 3:00pm
More Photos
From£98
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Columbia Downtown : 1233 Washington St.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
1233 Washington St., Columbia, SC 29201 +1-888-965-8297 ~3.47 miles northeast of Cayce
  • 3 star Downtown hotel
  • 90 sleeping rooms in hotel
More Photos
From£60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Marriott Columbia
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1200 Hampton St., Columbia, SC 29201 +1-888-906-6358 ~3.48 miles northeast of Cayce
  • Expensive Downtown hotel
  • Fitness + Health Center
More Photos
From£71
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia I-26 - Cayce
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
2125 Commerce Dr., Cayce, NC 29033 +1-888-749-6785
  • Low-priced property
  • Check-in time: 15:00
More Photos
From£45
Poor 2.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
180 Stoneridge Dr., Columbia, SC 29210 +1-888-878-9982 ~3.54 miles north of Cayce
  • Cheap Downtown hotel
  • 3 floors in property
More Photos
From£26
Average 3.0 /5 Read Reviews Call BookMore Details
Hotel Trundle : 1224 Taylor St.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
1224 Taylor St., Columbia, SC 29201 +1-888-389-4485 ~3.56 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • Check-in time: 3pm
More Photos
From£113
Very good 4.0 /5 Review Score Call BookMore Details
Graduate by Hilton Columbia SC : 1619 Pendleton St.
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1619 Pendleton St., Columbia, SC 29201 +1-888-389-4121 ~3.57 miles northeast of Cayce
  • High end Downtown hotel
  • Free breakfast
More Photos
From£98
Average 3.0 /5 Latest Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 - Columbia
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
450 Gracern Rd., Columbia, SC 29210 +1-888-675-2083 ~3.57 miles north of Cayce
  • Two-star property
  • 120 sleeping rooms in hotel
More Photos
From£20
Poor 2.0 /5 Review Score Call BookMore Details
Hampton Inn I 26 Airport : 1094 Chris Dr.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
1094 Chris Dr., West Columbia, SC 29169 +1-800-716-8490 ~3.61 miles northwest of Cayce
  • 3-star Highway hotel
  • Hotel has 4 floors
More Photos
From£60
Average 3.0 /5 Reviews Call BookMore Details
TRU Columbia Greystone in Columbia
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
183 Stoneridge Dr., Columbia, SC 29210 +1-800-805-5223 ~3.64 miles north of Cayce
  • Mid-scale Downtown property
  • 117 sleeping rooms in hotel
More Photos
From£68
Average 3.0 /5 Recent Reviews Call BookMore Details
Embassy Suites Columbia : 200 Stoneridge Dr.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
200 Stoneridge Dr., Columbia, SC 29210 +1-888-965-1860 ~3.65 miles north of Cayce
  • Mid-scale Suburban hotel
  • Airport shuttle available
More Photos
From£89
Very good 4.0 /5 Hotel Reviews Call BookMore Details
TRU by Hilton Columbia Greystone
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
185 Stoneridge Dr., Columbia, SC 29210 +1-888-788-5576 ~3.66 miles north of Cayce
  • 3-star Downtown hotel
  • Check in: 3:00pm
More Photos
From£60
Average 3.0 /5 Latest Reviews Call BookMore Details
Carolina University Inn : 1615 Gervais St.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
1615 Gervais St., Columbia, SC 29201 +1-888-897-9207 ~3.66 miles northeast of Cayce
  • Mid-scale Downtown hotel
  • 4 meeting rooms in property
More Photos
From£44
Poor 2.5 /5 Recent Reviews Call BookMore Details
Home2 Suites by Hilton Columbia Downtown in Columbia
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
1609 Gervais St., Columbia, SC 29201 +1-888-311-4278 ~3.67 miles northeast of Cayce
  • Three Star hotel
  • Hotel has 5 suites
More Photos
From£60
Average 3.0 /5 Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
110 Mcswain Dr., West Columbia, SC 29169 +1-888-469-4795 ~3.76 miles northwest of Cayce
  • 3-star Airport hotel
  • 33 suites in hotel
More Photos
From£72
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Oyo Hotel Columbia Sc West - Columbia
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
114 Mcswain Dr., Columbia, SC 29169 +1-888-734-9421 ~3.86 miles northwest of Cayce
  • Three Star hotel
  • 40 rooms in property
More Photos
From£68
Very good 4.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Columbia
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
230 Greystone Blvd., Columbia, SC 29210 +1-888-841-5292 ~3.91 miles north of Cayce
  • Affordable Downtown property
  • Hotel has 81 suites
More Photos
From£57
Average 3.0 /5 Hotel Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington in West Columbia
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
122 Mathias Rd., West Columbia, SC 29169 +1-888-455-5160 ~4.07 miles northwest of Cayce
  • Midscale Highway hotel
  • Hotel has 108 suites
More Photos
From£57
Average 3.0 /5 Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington : 2915 Sunset Blvd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
2915 Sunset Blvd., West Columbia, SC 29169 +1-888-965-8297 ~4.18 miles northwest of Cayce
  • Three Star property
  • 111 suites in hotel
More Photos
From£57
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia in Columbia
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
911 Bush River Rd., Columbia, SC 29210 +1-888-906-6358 ~5.07 miles north of Cayce
  • Affordable Highway property
  • Hotel has 2 meeting rooms
More Photos
From£47
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Columbia - Columbia
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
1144 Bush River Rd., Columbia, SC 29210 +1-888-749-6785 ~5.13 miles northwest of Cayce
  • Economical property
More Photos
From£45
Terrible 1.0 /5 Read Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
200 Zimalcrest Dr., Columbia, SC 29210 +1-888-878-9982 ~5.29 miles northwest of Cayce
  • 3-star Suburban property
  • Access to gym on-site
More Photos
From£37
Average 3.0 /5 Recent Reviews Call BookMore Details

Next: See My Cayce Hotels with Pricing

Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
Back to Top
Table of Contents Top: Check Rates Cayce Hotels