Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels, Motels & Accommodations

Knights Inn Columbia Airport/Cayce : 1987 Airport Blvd. 1987 Airport Blvd., Cayce, SC 29033 Call
  • Low priced property
  • 2 floors in property
Econo Lodge Inn & Suites Cayce I-26 Airport 1935 Airport Blvd., Cayce, SC 29033 Call
  • Economy Airport hotel
  • 51 rooms in hotel
From£50
Very good 4.0 /5 Latest Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott 613 Knox Abbott Dr., Cayce, NC 29033 Call
  • Mid-scale property
  • Check-in: 15:00
From£54
Average 3.0 /5 Guest Reviews Call BookMore Details
Motel 6 West Columbia Sc Airport 650 Cherokee Lane, West Columbia, SC 29169 Call ~1.52 miles west of Cayce
  • Two-star Airport hotel
  • Hotel has 115 rooms
From£43
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 West Columbia Sc in West Columbia 2200 Airport Blvd., West Columbia, SC 29170 Call ~1.66 miles west of Cayce
  • 2-star hotel
  • 82 sleeping rooms in hotel
From£43
Average 3.0 /5 Hotel Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport - West Columbia 2204 Airport Blvd., West Columbia, SC 29170 Call ~1.70 miles west of Cayce
  • 2-star Airport hotel
  • Hotel has 2 floors
From£47
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170 Call ~1.74 miles west of Cayce
  • 2-star Airport property
  • Check in: 2:00pm
From£43
Very good 4.0 /5 Read Reviews Call BookMore Details
Country Inn & Suites Columbia Airport 2245 Airport Blvd., Cayce, SC 29033 Call
  • 3-star Airport hotel
  • 64 rooms in property
From£47
Very good 4.5 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport 110 Branch Rd., West Columbia, SC 29170 Call ~1.82 miles west of Cayce
  • 2-star Airport hotel
  • Free breakfast available
Clarion Inn Airport West Columbia in West Columbia 29169, West Columbia, SC 29169 Call ~2.17 miles north of Cayce
  • Three Star Airport property
  • 2 floors in property
From£58
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites 3020 Charleston Highway, West Columbia, SC 29172 Call ~2.40 miles south of Cayce
  • 3 star Airport hotel
  • Check in: 15:00
From£58
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce 1125 Fort Congaree Trail, Cayce, SC 29033 Call
  • Affordable Highway hotel
  • 3 suites in hotel
From£72
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Columbia Airport in West Columbia 2516 Augusta Rd., West Columbia, SC 29169 Website Call ~2.53 miles northwest of Cayce
  • Low Cost Airport property
  • 2 floors in property
From£43
Average 3.0 /5 Reviews Call BookMore Details
Clarion Inn Columbia Airport 500 Chris Dr., West Columbia, SC 29169 Call ~2.67 miles northwest of Cayce
  • Mid-scale Airport property
  • 5 meeting rooms in property
From£38
Very good 4.0 /5 Recent Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201 Call ~2.80 miles east of Cayce
  • Low-priced Downtown hotel
  • 3 floors in property
From£43
Average 3.0 /5 Hotel Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista : 511 Lady St. 511 Lady St., Columbia, SC 29201 Call ~2.83 miles northeast of Cayce
  • Midscale Downtown hotel
  • Gym / Fitness Center Available
From£72
Very good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC 630 Assembly St., Columbia, SC 29201 Call ~2.95 miles northeast of Cayce
  • Affordable Downtown property
  • Gym / Fitness Center Available
From£72
Very good 4.0 /5 Review Score Call BookMore Details
Hampton Inn Columbia-Downtown Historic District in Columbia 822 Gervais St., Columbia, SC 29201 Call ~3.00 miles northeast of Cayce
  • Affordable Downtown hotel
  • Check in: 3:00PM
From£91
Very good 4.5 /5 Guest Reviews Call BookMore Details
Hilton Columbia Center 924 Senate St., Columbia, SC 29201 Call ~3.01 miles northeast of Cayce
  • High end Downtown property
  • 222 rooms in property
From£73
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista - Columbia 819 Gervais St., Columbia, SC 29201 Call ~3.02 miles northeast of Cayce
  • 3-star Downtown hotel
  • 130 suites in property
From£58
Average 3.0 /5 Hotel Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown 501 Taylor St., Columbia, SC 29201 Call ~3.05 miles north of Cayce
  • Affordable Downtown hotel
  • Fitness center on property
From£94
Average 3.0 /5 Hotel Reviews Call BookMore Details
Aloft Columbia Downtown in Columbia 823 Lady St., Columbia, SC 29201 Call ~3.06 miles northeast of Cayce
  • 3-star Downtown hotel
  • Check-in time: 3:00pm
From£58
Very good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih 901 Washington St., Columbia, SC 29201 Call ~3.18 miles northeast of Cayce
  • Mid-scale property
  • Hotel has 105 rooms
From£65
Very good 4.0 /5 Latest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista - Columbia 1000 Lady St., Columbia, SC 29201 Website Call ~3.18 miles northeast of Cayce
  • Affordable Downtown property
  • 6 suites in hotel
From£72
Average 3.0 /5 Recent Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel in Columbia 1913 Huger St., Columbia, SC 29201 Call ~3.26 miles north of Cayce
  • Mid-scale Downtown hotel
  • 93 suites in property
From£79
Very good 4.0 /5 Guest Reviews Call BookMore Details
Moxy Columbia Downtown in Columbia 1200 Main St., Columbia, SC 29201 Call ~3.31 miles northeast of Cayce
  • 4-star property
From£91
Average 3.0 /5 Read Reviews Call BookMore Details
Microtel 1301 Main St., Columbia, SC 29201 Call ~3.33 miles northeast of Cayce
  • 2-star Downtown property
  • Free breakfast available
From£32
Average 3.0 /5 Guest Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel - Columbia 1400 Main St., Columbia, SC 29201 Call ~3.43 miles northeast of Cayce
  • High-end Downtown hotel
  • Check in time: 3:00pm
From£94
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Columbia Downtown 1233 Washington St., Columbia, SC 29201 Call ~3.47 miles northeast of Cayce
  • 3 star Downtown property
  • Fitness / Gym is on-site
From£58
Average 3.0 /5 Reviews Call BookMore Details
Marriott Columbia : 1200 Hampton St. 1200 Hampton St., Columbia, SC 29201 Call ~3.48 miles northeast of Cayce
  • Expensive Downtown hotel
  • 300 rooms in property
From£68
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Masters Inn Columbia I-26 2125 Commerce Dr., Cayce, NC 29033 Call
  • Economy hotel
  • Check-in: 15:00
Extended Stay America Suites Columbia Greystone : 180 Stoneridge Dr. 180 Stoneridge Dr., Columbia, SC 29210 Call ~3.54 miles north of Cayce
  • Cheap Downtown property
  • 72 rooms in property
From£25
Average 3.0 /5 Reviews Call BookMore Details
Hotel Trundle 1224 Taylor St., Columbia, SC 29201 Call ~3.56 miles northeast of Cayce
  • 3-star Downtown property
  • Hotel has an eco-friendly policy Learn more
From£108
Very good 4.0 /5 Review Score Call BookMore Details
Graduate by Hilton Columbia SC 1619 Pendleton St., Columbia, SC 29201 Call ~3.57 miles northeast of Cayce
  • High-end Downtown property
  • Gym is available on property
From£94
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 - Columbia 450 Gracern Rd., Columbia, SC 29210 Call ~3.57 miles north of Cayce
  • Cheap property
  • Free breakfast
Hampton Inn I 26 Airport 1094 Chris Dr., West Columbia, SC 29169 Call ~3.61 miles northwest of Cayce
  • Affordable Highway property
  • 120 rooms in hotel
From£58
Average 3.0 /5 Review Score Call BookMore Details
TRU Columbia Greystone - Columbia 183 Stoneridge Dr., Columbia, SC 29210 Call ~3.64 miles north of Cayce
  • 3-star Downtown hotel
  • 117 rooms in property
From£65
Average 3.0 /5 Guest Reviews Call BookMore Details
Embassy Suites Columbia 200 Stoneridge Dr., Columbia, SC 29210 Call ~3.65 miles north of Cayce
  • Midscale Suburban hotel
  • Check-in time: 3:00 PM
From£86
Very good 4.0 /5 Recent Reviews Call BookMore Details
TRU by Hilton Columbia Greystone 185 Stoneridge Dr., Columbia, SC 29210 Call ~3.66 miles north of Cayce
  • Mid-scale Downtown hotel
  • 117 rooms in hotel
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Carolina University Inn 1615 Gervais St., Columbia, SC 29201 Call ~3.66 miles northeast of Cayce
  • 3-star Downtown property
  • 89 sleeping rooms in hotel
Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201 Call ~3.67 miles northeast of Cayce
  • 3 star hotel
  • 5 suites in hotel
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport 110 Mcswain Dr., West Columbia, SC 29169 Call ~3.76 miles northwest of Cayce
  • Mid-scale Airport hotel
  • 5 floors in hotel
From£69
Very good 4.0 /5 Read Reviews Call BookMore Details
Oyo Hotel Columbia Sc West 114 Mcswain Dr., Columbia, SC 29169 Call ~3.86 miles northwest of Cayce
  • Mid-scale property
  • Hotel has 40 rooms
From£65
Very good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Columbia 230 Greystone Blvd., Columbia, SC 29210 Call ~3.91 miles north of Cayce
  • 3 star Downtown property
  • Complimentary breakfast is offered
From£54
Average 3.0 /5 Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington : 122 Mathias Rd. 122 Mathias Rd., West Columbia, SC 29169 Call ~4.07 miles northwest of Cayce
  • Three Star Highway property
  • 108 rooms in hotel
From£54
Average 3.0 /5 Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington 2915 Sunset Blvd., West Columbia, SC 29169 Call ~4.18 miles northwest of Cayce
  • Mid-scale property
  • 111 rooms in property
From£54
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia in Columbia 911 Bush River Rd., Columbia, SC 29210 Call ~5.07 miles north of Cayce
  • Midscale Highway property
  • Free breakfast available
From£45
Very good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Columbia in Columbia 1144 Bush River Rd., Columbia, SC 29210 Call ~5.13 miles northwest of Cayce
  • Inexpensive hotel
From£43
Terrible 1.0 /5 Guest Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia 200 Zimalcrest Dr., Columbia, SC 29210 Call ~5.29 miles northwest of Cayce
  • Midscale Suburban hotel
  • 2 floors in property
From£35
Average 3.0 /5 Guest Reviews Call BookMore Details

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Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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