Cayce South Carolina Hotels & Motels

Find hotels & motels in Cayce using the list below. Find discounted hotel accommodations in or close to Cayce, SC for your upcoming individual or group travel. We provide the best Cayce, South Carolina hotel and motel rooms. Browse the Cayce area hotels to find the perfect lodging! Please use the provided map of the Cayce hotels. Need 5+ Rooms? Secure Cayce Group Hotel Discounts

The Cayce center point is about 2 miles south of Edventure Children’s Museum and 2 miles southwest of Columbia Amtrak.

Cayce Hotels/Motels & Accommodations

Country Hearth Inn & Suites Cayce / Columbia in Cayce 3020 Charleston Highway, Cayce, SC 29033 Call
  • Low Cost property
From£44
Average 3.0 /5 Reviews Call BookMore Details
Knights Inn Columbia Airport/Cayce 1987 Airport Blvd., Cayce, SC 29033 Call
  • Economical property
  • Free comp. breakfast
Econo Lodge Inn & Suites Cayce I-26 Airport - Cayce 1935 Airport Blvd., Cayce, SC 29033 Call
  • Economical Airport hotel
  • 51 rooms in hotel
From£50
Very good 4.0 /5 Guest Reviews Call BookMore Details
Masters Inn Columbia Knox Abbott : 613 Knox Abbott Dr. 613 Knox Abbott Dr., Cayce, NC 29033 Call
  • Mid-scale property
  • Check in time: 15:00
From£54
Average 3.0 /5 Review Score Call BookMore Details
Motel 6 West Columbia Sc Airport in West Columbia 650 Cherokee Lane, West Columbia, SC 29169 Call ~1.52 miles west of Cayce
  • Economical Airport hotel
  • Free complimentary breakfast
From£44
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 West Columbia Sc 2200 Airport Blvd., West Columbia, SC 29170 Call ~1.66 miles west of Cayce
  • Cheap hotel
From£44
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Columbia, SC Airport - West Columbia 2204 Airport Blvd., West Columbia, SC 29170 Call ~1.70 miles west of Cayce
  • Inexpensive Airport property
  • Check in time: 3:00PM
From£47
Average 3.0 /5 Review Score Call BookMore Details
Sleep Inn Airport 2208 Airport Blvd., West Columbia, SC 29170 Call ~1.74 miles west of Cayce
  • 2 star Airport property
  • Hotel has 69 rooms
From£44
Very good 4.0 /5 Read Reviews Call BookMore Details
Country Inn & Suites Columbia Airport - Cayce 2245 Airport Blvd., Cayce, SC 29033 Call
  • Midscale Airport property
  • Airport shuttle provided
From£47
Very good 4.5 /5 Guest Reviews Call BookMore Details
Days Inn & Suites by Wyndham Columbia Airport : 110 Branch Rd. 110 Branch Rd., West Columbia, SC 29170 Call ~1.82 miles west of Cayce
  • Two-star Airport hotel
Clarion Inn Airport West Columbia - West Columbia 29169, West Columbia, SC 29169 Call ~2.17 miles north of Cayce
  • 3 star Airport hotel
  • Hotel has 5 meeting rooms
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites : 3020 Charleston Highway 3020 Charleston Highway, West Columbia, SC 29172 Call ~2.40 miles south of Cayce
  • 3-star Airport property
  • Check in: 15:00
From£58
Average 3.0 /5 Reviews Call BookMore Details
Courtyard by Marriott Columbia Cayce - Cayce 1125 Fort Congaree Trail, Cayce, SC 29033 Call
  • 3 star Highway hotel
  • 4 floors in property
From£72
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn Columbia Airport 2516 Augusta Rd., West Columbia, SC 29169 Website Call ~2.53 miles northwest of Cayce
  • Cheap Airport hotel
  • Check in time: 3:00
From£44
Average 3.0 /5 Reviews Call BookMore Details
Clarion Inn Columbia Airport : 500 Chris Dr. 500 Chris Dr., West Columbia, SC 29169 Call ~2.67 miles northwest of Cayce
  • Midscale Airport property
  • 142 sleeping rooms in hotel
From£38
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Gallus Stadium Park Inn Ascend Hotel Collection 621 South Assembly St., Columbia, SC 29201 Call ~2.80 miles east of Cayce
  • Two star Downtown hotel
  • Check-in time: 3p.m.
From£44
Average 3.0 /5 Read Reviews Call BookMore Details
SpringHill Suites by Marriott Columbia Downtown/The Vista : 511 Lady St. 511 Lady St., Columbia, SC 29201 Call ~2.83 miles northeast of Cayce
  • 3 star Downtown hotel
  • 5 floors in property
From£72
Very good 4.0 /5 Review Score Call BookMore Details
Courtyard by Marriott Columbia Downtown at USC in Columbia 630 Assembly St., Columbia, SC 29201 Call ~2.95 miles northeast of Cayce
  • Affordable Downtown property
  • 9 floors in hotel
From£72
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn Columbia-Downtown Historic District in Columbia 822 Gervais St., Columbia, SC 29201 Call ~3.00 miles northeast of Cayce
  • 3 star Downtown property
  • 5 floors in property
From£91
Very good 4.5 /5 Latest Reviews Call BookMore Details
Hilton Columbia Center 924 Senate St., Columbia, SC 29201 Call ~3.01 miles northeast of Cayce
  • 4 star Downtown property
  • Fitness center on property
From£74
Very good 4.0 /5 Reviews Call BookMore Details
Hyatt Place Columbia / Downtown / The Vista 819 Gervais St., Columbia, SC 29201 Call ~3.02 miles northeast of Cayce
  • Affordable Downtown hotel
  • 130 rooms in hotel
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites Columbia Downtown : 501 Taylor St. 501 Taylor St., Columbia, SC 29201 Call ~3.05 miles north of Cayce
  • Affordable Downtown hotel
  • 4 floors in hotel
From£94
Average 3.0 /5 Latest Reviews Call BookMore Details
Aloft Columbia Downtown - Columbia 823 Lady St., Columbia, SC 29201 Call ~3.06 miles northeast of Cayce
  • Midscale Downtown property
  • 107 sleeping rooms in hotel
From£58
Very good 4.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express & Suites Columbia Downtown – The Vista An Ih - Columbia 901 Washington St., Columbia, SC 29201 Call ~3.18 miles northeast of Cayce
  • 3-star hotel
  • Check-in time: 15:00
From£66
Very good 4.0 /5 Latest Reviews Call BookMore Details
Cambria Hotel Columbia Downtown The Vista - Columbia 1000 Lady St., Columbia, SC 29201 Website Call ~3.18 miles northeast of Cayce
  • Affordable Downtown hotel
  • 6 suites in hotel
From£72
Average 3.0 /5 Read Reviews Call BookMore Details
Staybridge Suites Columbia An Ihg Hotel 1913 Huger St., Columbia, SC 29201 Call ~3.26 miles north of Cayce
  • 3-star Downtown hotel
  • Free breakfast
From£80
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Moxy Columbia 1200 Main St., Columbia, SC 29201 Call ~3.31 miles northeast of Cayce
  • Affordable hotel
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Microtel 1301 Main St., Columbia, SC 29201 Call ~3.33 miles northeast of Cayce
  • Two star Downtown property
  • Check-in time: 3:00 PM
From£33
Average 3.0 /5 Recent Reviews Call BookMore Details
Sheraton Columbia Downtown Hotel : 1400 Main St. 1400 Main St., Columbia, SC 29201 Call ~3.43 miles northeast of Cayce
  • 4 star Downtown property
  • 132 rooms in property
From£94
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Columbia Downtown : 1233 Washington St. 1233 Washington St., Columbia, SC 29201 Call ~3.47 miles northeast of Cayce
  • Mid-scale Downtown property
  • Has environment-friendly policy Learn more
From£58
Average 3.0 /5 Latest Reviews Call BookMore Details
Marriott Columbia in Columbia 1200 Hampton St., Columbia, SC 29201 Call ~3.48 miles northeast of Cayce
  • High-end Downtown property
  • Hotel has 15 suites
From£69
Very good 4.0 /5 Reviews Call BookMore Details
Masters Inn Columbia I-26 in Cayce 2125 Commerce Dr., Cayce, NC 29033 Call
  • 2 star property
From£44
Poor 2.0 /5 Reviews Call BookMore Details
Extended Stay America Suites Columbia Greystone : 180 Stoneridge Dr. 180 Stoneridge Dr., Columbia, SC 29210 Call ~3.54 miles north of Cayce
  • Two star Downtown hotel
  • Free complimentary breakfast
From£25
Average 3.0 /5 Guest Reviews Call BookMore Details
Hotel Trundle 1224 Taylor St., Columbia, SC 29201 Call ~3.56 miles northeast of Cayce
  • Three Star Downtown property
  • Hotel has 41 rooms
From£109
Very good 4.0 /5 Guest Reviews Call BookMore Details
Graduate by Hilton Columbia SC : 1619 Pendleton St. 1619 Pendleton St., Columbia, SC 29201 Call ~3.57 miles northeast of Cayce
  • 4-star Downtown property
  • Fitness / Gym is on-site
From£94
Average 3.0 /5 Read Reviews Call BookMore Details
Extended Stay America Suites Columbia West Interstate 126 : 450 Gracern Rd. 450 Gracern Rd., Columbia, SC 29210 Call ~3.57 miles north of Cayce
  • Cheap property
  • Check in time: 3:00pm
Hampton Inn I 26 Airport : 1094 Chris Dr. 1094 Chris Dr., West Columbia, SC 29169 Call ~3.61 miles northwest of Cayce
  • Mid-scale Highway property
  • Hotel has 120 rooms
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
TRU Columbia Greystone 183 Stoneridge Dr., Columbia, SC 29210 Call ~3.64 miles north of Cayce
  • Midscale Downtown hotel
  • 117 rooms in hotel
From£66
Average 3.0 /5 Guest Reviews Call BookMore Details
Embassy Suites Columbia : 200 Stoneridge Dr. 200 Stoneridge Dr., Columbia, SC 29210 Call ~3.65 miles north of Cayce
  • Affordable Suburban property
  • 7 floors in property
From£86
Very good 4.0 /5 Recent Reviews Call BookMore Details
TRU by Hilton Columbia Greystone : 185 Stoneridge Dr. 185 Stoneridge Dr., Columbia, SC 29210 Call ~3.66 miles north of Cayce
  • Midscale Downtown property
  • Gym / Fitness Center Available
From£58
Average 3.0 /5 Read Reviews Call BookMore Details
Carolina University Inn in Columbia 1615 Gervais St., Columbia, SC 29201 Call ~3.66 miles northeast of Cayce
  • 3-star Downtown hotel
  • Check-in time: 3:00 PM
Home2 Suites by Hilton Columbia Downtown 1609 Gervais St., Columbia, SC 29201 Call ~3.67 miles northeast of Cayce
  • Affordable property
  • Check in time: 15:00
From£58
Average 3.0 /5 Reviews Call BookMore Details
Hilton Garden Inn Columbia Airport in West Columbia 110 Mcswain Dr., West Columbia, SC 29169 Call ~3.76 miles northwest of Cayce
  • Mid-scale Airport hotel
  • Hotel has 33 suites
From£69
Very good 4.0 /5 Review Score Call BookMore Details
Oyo Hotel Columbia Sc West in Columbia 114 Mcswain Dr., Columbia, SC 29169 Call ~3.86 miles northwest of Cayce
  • Midscale property
  • Check-in: 15:00
From£66
Very good 4.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton Columbia : 230 Greystone Blvd. 230 Greystone Blvd., Columbia, SC 29210 Call ~3.91 miles north of Cayce
  • Affordable Downtown hotel
  • Comp. Breakfast
From£55
Average 3.0 /5 Latest Reviews Call BookMore Details
Residence Inn by Marriott Columbia West / Lexington 122 Mathias Rd., West Columbia, SC 29169 Call ~4.07 miles northwest of Cayce
  • 3-star Highway property
  • 108 rooms in property
From£55
Average 3.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites Columbia West / Lexington in West Columbia 2915 Sunset Blvd., West Columbia, SC 29169 Call ~4.18 miles northwest of Cayce
  • Three Star property
  • Check-in time: 3:00pm
From£55
Very good 4.0 /5 Review Score Call BookMore Details
Comfort Inn Columbia - Columbia 911 Bush River Rd., Columbia, SC 29210 Call ~5.07 miles north of Cayce
  • Mid-scale Highway property
  • Check in time: 3:00 PM
From£45
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham Columbia 1144 Bush River Rd., Columbia, SC 29210 Call ~5.13 miles northwest of Cayce
  • Low-priced property
From£44
Terrible 1.0 /5 Read Reviews Call BookMore Details
Hawthorn Suites by Wyndham Columbia : 200 Zimalcrest Dr. 200 Zimalcrest Dr., Columbia, SC 29210 Call ~5.29 miles northwest of Cayce
  • Affordable Suburban hotel
  • Hotel has 64 rooms
From£36
Average 3.0 /5 Reviews Call BookMore Details

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Verified reviews of the city: Cayce, SC

Below are reviews of the city of Cayce, SC from an actual visitor's perspective.

"Great city with great people!"
Score 5.0 / 5

I used to live there. Great city with great people

Ella P., from 20-Sep-2025
"Great area"
Score 5.0 / 5

Charles A., from 05-Sep-2025
"Good Food!"
Score 5.0 / 5

How friendly everyone is and the good food.

Armon T., from 06-Feb-2024
"The people are courteous and very warm hearted."
Score 5.0 / 5

The people are courteous and very warm hearted.

Jeffrey W., from 05-Aug-2023
"Nice!"
Score 4.0 / 5

It was nice.

Robert P., from 16-Nov-2021
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