The Oranjestad center point is around the area of Alhambra Casino and the area of Eagle Beach.
Below are reviews of the city of Oranjestad, Aruba from an actual visitor's perspective.
Plenty of entertainment. Water activities are reasonable as are spa treatments!
The people were friendly and there food awesome. Shopping was great, especially the souvenir store VIP and the Bar I. The center across from Marriott near the Blue Horse. Oh can't forget the awesome beer and the Ariba Ariba
The city was clean, quiet and felt safe.
I didn't get out of the resort much, but when I did, I found the city very comfortable. I felt safe the entire time. I felt like the island was set up to be enjoyed by everyone there, not only the tourists.