Hotels in 50380 - Des Moines IA

Only hotels in 50380 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50380 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

50380 Hotels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton : 1000 Walnut St.
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1000 Walnut St., Des Moines, IA 50309 +1-888-389-4121 ~0.49 miles east of 50380
  • High-end Downtown property
  • Gym / Fitness Center Available
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From$149
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites Des Moines Downtown in Des Moines
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
333 SW 11th St., Des Moines, IA 50309 +1-888-675-2083 ~0.60 miles east of 50380
  • 3-star Downtown hotel
  • Hotel has 4 floors
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From$99
Very Good 4.5 /5 Guest Reviews Call BookMore Details
Des Lux Hotel
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
800 Locust St., Des Moines, IA 50309 +1-800-716-8490 ~0.64 miles east of 50380
  • Midscale Downtown hotel
  • 5 floors in hotel
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From$179
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Des Moines Marriott Downtown in Des Moines
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
700 Grand Ave., Des Moines, IA 50309 +1-800-805-5223 ~0.69 miles east of 50380
  • Four-star Downtown hotel
  • Hotel has 415 rooms
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From$75
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Hyatt Place Des Moines Downtown : 418 6th Ave.
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
418 6th Ave., Des Moines, IA 50309 +1-888-965-1860 ~0.75 miles east of 50380
  • Affordable Downtown hotel
  • 6 suites in hotel
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From$144
Average 3.0 /5 Hotel Reviews Call BookMore Details
Hyatt Place Des Moines / Downtown - Des Moines
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
418 6th Ave., Des Moines, IA 50309 +1-888-788-5576 ~0.75 miles east of 50380
  • 4 star Downtown hotel
  • Check in: 3:00p
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From$75
Average 3.0 /5 Reviews Call BookMore Details
Surety Hotel in Des Moines
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
206 6th Ave., Des Moines, IA 50309 +1-888-897-9207 ~0.76 miles east of 50380
  • Midscale property
  • Check-in: 15:00
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From$90
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Renaissance Des Moines Savery Hotel - Des Moines
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
401 Locust St., Des Moines, IA 50309 +1-888-311-4278 ~0.88 miles east of 50380
  • Midscale hotel
  • Hotel has 200 rooms
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From$149
Very Good 4.0 /5 Read Reviews Call BookMore Details
Hilton Des Moines Downtown : 435 Park St.
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
435 Park St., Des Moines, IA 50309 +1-888-469-4795 ~0.95 miles northeast of 50380
  • Four-star hotel
  • 8 floors in hotel
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From$99
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Residence Inn Des Moines Downtown
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
100 SW Water St., Des Moines, IA 50309 +1-888-734-9421 ~1.13 miles east of 50380
  • 3 star Downtown hotel
  • Hotel has a green policy Learn more
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From$99
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Downtown Mercy Area An Ihg Hotel
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1050 6th Ave., Des Moines, IA 50314 +1-888-841-5292 ~1.13 miles northeast of 50380
  • Mid-scale Downtown hotel
  • 251 sleeping rooms in hotel
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From$65
Very Good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Des Moines Downtown
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
120 SW Water St., Des Moines, IA 50309 +1-888-455-5160 ~1.13 miles east of 50380
  • 3 star Downtown hotel
  • Hotel has 41 suites
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From$98
Very Good 4.0 /5 Read Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown : 207 Crocker St.
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
207 Crocker St., Des Moines, IA 50309 +1-888-965-8297 ~1.19 miles northeast of 50380
  • Low priced Downtown hotel
  • Fitness / Gym is on-site
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From$129
Average 3.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express Des Moines, an IHG Hotel - Des Moines
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1140 24t St., Des Moines, IA 50311 +1-888-906-6358 ~1.23 miles northwest of 50380
  • Inexpensive Suburban hotel
  • Free breakfast available
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From$99
Very Good 4.0 /5 Review Score Call BookMore Details
Comfort Inn & Suites Event Center
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309 +1-888-749-6785 ~1.23 miles northeast of 50380
  • Two-star Downtown hotel
  • Airport shuttle available
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From$120
Very Good 4.0 /5 Review Score Call BookMore Details
Embassy Suites Hotel Des Moines Downtown
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
101 East Locust St., Des Moines, IA 50309 +1-888-878-9982 ~1.26 miles east of 50380
  • 3 star Downtown property
  • Free breakfast available
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From$75
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Staybridge Suites Des Moines Downtown
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
201 East Locust St., Des Moines, IA 50309 +1-888-389-4485 ~1.33 miles east of 50380
  • Affordable Downtown property
  • Access to gym on-site
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From$99
Very Good 4.5 /5 Reviews Call BookMore Details
Home2 Suites Des Moines at Drake University
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2650 University Ave., Des Moines, IA 50311 +1-888-389-4121 ~1.37 miles northwest of 50380
  • 3-star Downtown property
  • 2 meeting rooms in property
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
AC Hotel Des Moines East Village in Des Moines
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
401 East Grand Ave., Des Moines, IA 50309 +1-888-675-2083 ~1.45 miles east of 50380
  • 3-star Downtown hotel
  • Airport shuttle provided
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From$129
Very Good 4.0 /5 Review Score Call BookMore Details
Motel 6 Des Moines Sou Airport
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4817 Fleur Dr., Des Moines, IA 50321 +1-800-716-8490 ~2.98 miles south of 50380
  • Economy hotel
  • Check-in time: 15:00
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From$60
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Des Moines-Airport in Des Moines
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
5001 Fleur Dr., Des Moines, IA 50321 +1-800-805-5223 ~3.10 miles south of 50380
  • Three Star Airport hotel
  • Complimentary breakfast is offered
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From$69
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport : 1901 Hackley Ave.
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1901 Hackley Ave., Des Moines, IA 50315 +1-888-965-1860 ~3.11 miles south of 50380
  • Economy Airport hotel
  • Free breakfast
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From$64
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Americinn by Wyndham Des Moines Airport
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1920 Hackley Ave., Des Moines, IA 50315 +1-888-788-5576 ~3.16 miles south of 50380
  • Two-star Airport property
  • Check in: 3:00pm
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From$65
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn & Suites Des Moines Airport : 5231 Fleur Dr.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
5231 Fleur Dr., Des Moines, IA 50321 +1-888-897-9207 ~3.23 miles south of 50380
  • Affordable Airport hotel
  • Hotel has 55 rooms
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From$80
Very Good 4.0 /5 Review Score Call BookMore Details
Holiday Inn Des Moines-Airport/Conf Center, an IHG Hotel : 6111 Fleur Dr.
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6111 Fleur Dr., Des Moines, IA 50321 +1-888-311-4278 ~3.77 miles south of 50380
  • 3-star Airport hotel
  • 4 suites in hotel
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From$108
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham West Des Moines : 1258 8th St.
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1258 8th St., West Des Moines, IA 50265 +1-888-469-4795 ~3.86 miles west of 50380
  • 2-star Suburban property
  • Hotel has 2 floors
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From$50
Average 3.0 /5 Read Reviews Call BookMore Details
Clarion Inn - Des Moines
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1810 Army Post Rd., Des Moines, IA 50315 +1-888-734-9421 ~4.00 miles south of 50380
  • 3 star Airport property
  • Access to gym on-site
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Des Moines Airport : 6800 Fleur Dr.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
6800 Fleur Dr., Des Moines, IA 50321 +1-888-841-5292 ~4.23 miles south of 50380
  • Affordable Airport property
  • 10 suites in hotel
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From$80
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Econo Lodge Inn & Suites Fairgrounds : 410 East 30th St.
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
410 East 30th St., Des Moines, IA 50317 +1-888-455-5160 ~4.24 miles east of 50380
  • Low Cost Rural property
  • Check-in: 3:00 PM
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From$50
Average 3.0 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Airport
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
6880 Fleur Dr., Des Moines, IA 50321 +1-888-965-8297 ~4.27 miles south of 50380
  • Mid-scale Airport property
  • Fitness + Health Center
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From$90
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Homewood Suites by Hilton Des Moines Airport
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
7201 SW 22nd St., Des Moines, IA 50321 +1-888-906-6358 ~4.48 miles south of 50380
  • 3-star Airport property
  • Hotel has 4 floors
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Des Moines North
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-749-6785 ~4.74 miles northeast of 50380
  • Economy Highway property
  • 2 floors in property
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From$55
Average 3.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Des Moines North in Des Moines
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-878-9982 ~4.75 miles northeast of 50380
  • Two star Highway hotel
  • 6 suites in hotel
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From$50
Poor 2.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Des Moines : 4685 a Northeast 14th St.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
4685 a Northeast 14th St., Des Moines, IA 50313 +1-888-389-4485 ~4.75 miles northeast of 50380
  • Low priced Highway hotel
  • Access to gym on-site
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From$54
Very Good 4.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Des Moines Airport
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
6221 Willow Creek Ave., Des Moines, IA 50321 +1-888-389-4121 ~5.03 miles southwest of 50380
  • Two star Airport hotel
  • 6 meeting rooms in property
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From$62
Very Good 4.0 /5 Read Reviews Call BookMore Details
Quality Inn in Des Moines
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
4950 NE 14th St., Des Moines, IA 50313 +1-888-675-2083 ~5.04 miles northeast of 50380
  • Midscale Highway hotel
  • 3 floors in property
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From$57
Average 3.5 /5 Guest Reviews Call BookMore Details
Red Roof Inn Des Moines - Des Moines
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5020 NE 14th St., Des Moines, IA 50313 +1-800-716-8490 ~5.06 miles northeast of 50380
  • Low-priced Highway property
  • Has environment-friendly policy See policy
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From$60
Poor 2.0 /5 Reviews Call BookMore Details
Motel 6 Des Moines, IA - North : 4940 NE 14th St.
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
4940 NE 14th St., Des Moines, IA 50313 +1-800-805-5223 ~5.07 miles northeast of 50380
  • 2 star property
  • Check in: 14:00
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From$60
Poor 2.5 /5 Latest Reviews Call BookMore Details
Sonesta Essential Des Moines in Des Moines
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
4755 Merle Hay Rd., Des Moines, IA 50322 +1-888-965-1860 ~5.30 miles northwest of 50380
  • Cheap Highway property
  • 12 suites in property
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Extended Stay America Select Suites - Des Moines - West Des Moine in West Des Moines
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2701 Westown Pkwy., West Des Moines, IA 50266 +1-888-788-5576 ~5.36 miles west of 50380
  • Low priced hotel
  • Gym is available on property
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From$59
Average 3.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay in Des Moines
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
4845 Merle Hay Rd., Des Moines, IA 50322 +1-888-897-9207 ~5.38 miles northwest of 50380
  • Economy Highway hotel
  • Hotel has 76 rooms
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From$55
Average 3.0 /5 Hotel Reviews Call BookMore Details
Super 8 by Wyndham Urbandale/Des Moines Area
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
5900 Sutton Pl, Urbandale, IA 50322 +1-888-311-4278 ~5.49 miles northwest of 50380
  • Low priced Suburban property
  • 3 suites in hotel
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From$45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
4800 Merle Hay Rd., Des Moines, IA 50322 +1-888-469-4795 ~5.51 miles northwest of 50380
  • Affordable Suburban hotel
  • Check in: 3:00
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From$89
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50310 +1-888-734-9421 ~5.52 miles northwest of 50380
  • Low-priced property
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From$60
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road : 4995 Merle Hay Rd.
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50322 +1-888-841-5292 ~5.54 miles northwest of 50380
  • Mid-scale property
  • Free comp. breakfast
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From$62
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Ramada by Wyndham Des Moines Tropics Resort & Conference Center
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
5000 Merle Hay Rd., Des Moines, IA 50322 +1-888-455-5160 ~5.58 miles northwest of 50380
  • 3 star Suburban hotel
  • 18 suites in property
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From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Americinn by Wyndham Johnston Des Moines : 5050 Merle Hay Rd.
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
5050 Merle Hay Rd., Johnston, IA 50131 +1-888-965-8297 ~5.82 miles northwest of 50380
  • 2-star Highway hotel
  • Free complimentary breakfast
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From$64
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Urbandale / Des Moines - Urbandale
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
8711 Plum Dr., Urbandale, IA 50322 +1-888-906-6358 ~6.86 miles northwest of 50380
  • Low-priced Highway property
  • 25 suites in property
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From$60
Average 3.0 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Des Moines Urbandale
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8661 Plum Dr., Urbandale, IA 50322 +1-888-749-6785 ~6.87 miles northwest of 50380
  • Affordable Suburban property
  • Gym / Fitness Center Available
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From$84
Very Good 4.0 /5 Read Reviews Call BookMore Details
Grandstay Hotel & Suites in Johnston
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
6215 Merle Hay Rd., Johnston, IA 50131 +1-888-878-9982 ~6.88 miles northwest of 50380
  • Low priced Highway hotel
  • 4 floors in property
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
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