Hotels in 50380 - Des Moines IA

Only hotels in 50380 zip code are listed below. Search for cheap and discount hotel rates in Des Moines, IA for your upcoming leisure or conference / group travel. We list the best 50380 hotels and motels so you can review the Des Moines hotel list below to find the perfect lodging. Hotels in Polk county and area code 515 are also listed.

50380 Hotels/Motels & Accommodations

Hotel Fort Des Moines Curio Collection by Hilton
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
1000 Walnut St., Des Moines, IA 50309 +1-888-389-4121 ~0.49 miles east of 50380
  • Expensive Downtown hotel
  • Check-in time: 4:00 PM
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From$149
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Des Moines Downtown in Des Moines
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
333 SW 11th St., Des Moines, IA 50309 +1-888-675-2083 ~0.60 miles east of 50380
  • Midscale Downtown property
  • Fitness center on property
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From$99
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Des Lux Hotel
+1-800-716-8490

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New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
800 Locust St., Des Moines, IA 50309 +1-800-716-8490 ~0.64 miles east of 50380
  • 3-star Downtown hotel
  • 51 sleeping rooms in hotel
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From$179
Very good 4.0 /5 Recent Reviews Call BookMore Details
Des Moines Marriott Downtown : 700 Grand Ave.
+1-800-805-5223

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New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
700 Grand Ave., Des Moines, IA 50309 +1-800-805-5223 ~0.69 miles east of 50380
  • High-end Downtown hotel
  • 6 suites in property
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From$75
Very good 4.0 /5 Review Score Call BookMore Details
Hyatt Place Des Moines / Downtown : 418 6th Ave.
+1-888-965-1860

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New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
418 6th Ave., Des Moines, IA 50309 +1-888-965-1860 ~0.75 miles east of 50380
  • Four-star Downtown property
  • 7 floors in property
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Surety Hotel
+1-888-788-5576

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New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
206 6th Ave., Des Moines, IA 50309 +1-888-788-5576 ~0.76 miles east of 50380
  • 3-star property
  • Check in time: 15:00
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From$90
Very good 4.0 /5 Review Score Call BookMore Details
Hyatt Place Des Moines Downtown
+1-888-897-9207

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New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
418 6th Ave., Des Moines, IA 50309 +1-888-897-9207 ~0.76 miles east of 50380
  • Mid-scale Downtown hotel
  • Hotel has 5 suites
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From$93
Very good 4.5 /5 Latest Reviews Call BookMore Details
Renaissance Des Moines Savery Hotel in Des Moines
+1-888-311-4278

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New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
401 Locust St., Des Moines, IA 50309 +1-888-311-4278 ~0.88 miles east of 50380
  • Midscale hotel
  • 200 rooms in property
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From$149
Very good 4.0 /5 Review Score Call BookMore Details
Hilton Des Moines Downtown : 435 Park St.
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
435 Park St., Des Moines, IA 50309 +1-888-469-4795 ~0.95 miles northeast of 50380
  • 4 star property
  • Check-in time: 3:00 PM
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From$99
Very good 4.5 /5 Reviews Call BookMore Details
Residence Inn Des Moines Downtown - Des Moines
+1-888-734-9421

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New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
100 SW Water St., Des Moines, IA 50309 +1-888-734-9421 ~1.13 miles east of 50380
  • Midscale Downtown property
  • 127 sleeping rooms in hotel
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From$99
Average 3.0 /5 Reviews Call BookMore Details
Holiday Inn Downtown - Mercy Area by IHG : 1050 6th Ave.
+1-888-841-5292

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New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
1050 6th Ave., Des Moines, IA 50314 +1-888-841-5292 ~1.13 miles northeast of 50380
  • 3-star Downtown property
  • Has environment-friendly policy See policy
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From$65
Very good 4.0 /5 Review Score Call BookMore Details
Hampton Inn & Suites Des Moines Downtown
+1-888-455-5160

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New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
120 SW Water St., Des Moines, IA 50309 +1-888-455-5160 ~1.13 miles east of 50380
  • Three Star Downtown hotel
  • Hotel has 6 floors
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From$98
Very good 4.0 /5 Guest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Downtown in Des Moines
+1-888-965-8297

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New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
207 Crocker St., Des Moines, IA 50309 +1-888-965-8297 ~1.19 miles northeast of 50380
  • Inexpensive Downtown property
  • Hotel has 54 suites
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From$129
Average 3.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express Des Moines, an IHG Hotel in Des Moines
+1-888-906-6358

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New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
1140 24t St., Des Moines, IA 50311 +1-888-906-6358 ~1.23 miles northwest of 50380
  • Economical Suburban property
  • Fitness center on property
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From$99
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites Event Center in Des Moines
+1-888-749-6785

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New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
929 3rd St. Des Moines Ia 50309, Des Moines, IA 50309 +1-888-749-6785 ~1.23 miles northeast of 50380
  • 2 star Downtown hotel
  • Fitness + Health Center
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From$120
Very good 4.0 /5 Recent Reviews Call BookMore Details
Embassy Suites Hotel Des Moines Downtown : 101 East Locust St.
+1-888-878-9982

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New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
101 East Locust St., Des Moines, IA 50309 +1-888-878-9982 ~1.26 miles east of 50380
  • 3-star Downtown property
  • Fitness / Gym is on-site
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From$75
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Staybridge Suites Des Moines Downtown
+1-888-389-4485

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New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
201 East Locust St., Des Moines, IA 50309 +1-888-389-4485 ~1.33 miles east of 50380
  • 3-star Downtown hotel
  • Free breakfast available
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From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Home2 Suites Des Moines at Drake University in Des Moines
+1-888-389-4121

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New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
2650 University Ave., Des Moines, IA 50311 +1-888-389-4121 ~1.37 miles northwest of 50380
  • Mid-scale Downtown hotel
  • Check in time: 3:00 PM
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From$80
Very good 4.0 /5 Review Score Call BookMore Details
AC Hotel Des Moines East Village - Des Moines
+1-888-675-2083

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New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
401 East Grand Ave., Des Moines, IA 50309 +1-888-675-2083 ~1.45 miles east of 50380
  • Affordable Downtown property
  • Shuttle to airport available
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From$129
Very good 4.0 /5 Reviews Call BookMore Details
Motel 6 Des Moines Sou Airport : 4817 Fleur Dr.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
4817 Fleur Dr., Des Moines, IA 50321 +1-800-716-8490 ~2.98 miles south of 50380
  • Inexpensive hotel
  • Check in: 15:00
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From$60
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hampton Inn Des Moines-Airport
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
5001 Fleur Dr., Des Moines, IA 50321 +1-800-805-5223 ~3.10 miles south of 50380
  • Affordable Airport property
  • 120 rooms in hotel
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From$69
Very good 4.0 /5 Read Reviews Call BookMore Details
Days Inn & Suites by Wyndham Des Moines Airport in Des Moines
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
1901 Hackley Ave., Des Moines, IA 50315 +1-888-965-1860 ~3.11 miles south of 50380
  • Two-star Airport property
  • Airport shuttle provided
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From$64
Very good 4.0 /5 Guest Reviews Call BookMore Details
Americinn by Wyndham Des Moines Airport in Des Moines
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
1920 Hackley Ave., Des Moines, IA 50315 +1-888-788-5576 ~3.16 miles south of 50380
  • Two-star Airport property
  • Fitness center on property
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From$65
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Des Moines Airport
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
5231 Fleur Dr., Des Moines, IA 50321 +1-888-897-9207 ~3.23 miles south of 50380
  • Three Star Airport property
  • Shuttle to airport available
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From$80
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Des Moines-Airport/Conf Center by IHG
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
6111 Fleur Dr., Des Moines, IA 50321 +1-888-311-4278 ~3.77 miles south of 50380
  • Mid-scale Airport property
  • Shuttle to airport available
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From$108
Very good 4.0 /5 Guest Reviews Call BookMore Details
Days Inn by Wyndham West Des Moines
+1-888-469-4795

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New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
1258 8th St., West Des Moines, IA 50265 +1-888-469-4795 ~3.86 miles west of 50380
  • Economical Suburban hotel
  • 2 meeting rooms in hotel
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From$50
Average 3.0 /5 Hotel Reviews Call BookMore Details
Clarion Inn in Des Moines
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
1810 Army Post Rd., Des Moines, IA 50315 +1-888-734-9421 ~4.00 miles south of 50380
  • Mid-scale Airport property
  • Check-in: 4.00pm
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From$80
Average 3.0 /5 Review Score Call BookMore Details
Hilton Garden Inn Des Moines Airport
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
6800 Fleur Dr., Des Moines, IA 50321 +1-888-841-5292 ~4.23 miles south of 50380
  • 3-star Airport hotel
  • Airport shuttle available
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From$80
Very good 4.0 /5 Reviews Call BookMore Details
Econo Lodge Inn & Suites Fairgrounds in Des Moines
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
410 East 30th St., Des Moines, IA 50317 +1-888-455-5160 ~4.24 miles east of 50380
  • Economy Rural hotel
  • 3 floors in hotel
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From$50
Average 3.0 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Des Moines Airport in Des Moines
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
6880 Fleur Dr., Des Moines, IA 50321 +1-888-965-8297 ~4.27 miles south of 50380
  • 3 star Airport property
  • 3 floors in property
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From$90
Very good 4.0 /5 Recent Reviews Call BookMore Details
Homewood Suites by Hilton Des Moines Airport in Des Moines
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
7201 SW 22nd St., Des Moines, IA 50321 +1-888-906-6358 ~4.48 miles south of 50380
  • Three Star Airport hotel
  • 4 floors in hotel
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From$80
Average 3.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Des Moines North : 4685 NE 14th St.
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-749-6785 ~4.74 miles northeast of 50380
  • Low-priced Highway hotel
  • 64 rooms in hotel
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From$55
Average 3.0 /5 Review Score Call BookMore Details
Baymont by Wyndham Des Moines North
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
4685 NE 14th St., Des Moines, IA 50313 +1-888-878-9982 ~4.75 miles northeast of 50380
  • Two-star Highway property
  • 2 meeting rooms in hotel
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From$50
Poor 2.0 /5 Recent Reviews Call BookMore Details
Super 8 by Wyndham Des Moines : 4685 a Northeast 14th St.
+1-888-389-4485

How should we direct your call?

New Reservations: +1-888-389-4485 Group Sales: +1-888-494-8863
4685 a Northeast 14th St., Des Moines, IA 50313 +1-888-389-4485 ~4.75 miles northeast of 50380
  • Inexpensive Highway property
  • Access to gym on-site
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From$54
Very good 4.0 /5 Latest Reviews Call BookMore Details
Baymont by Wyndham Des Moines Airport in Des Moines
+1-888-389-4121

How should we direct your call?

New Reservations: +1-888-389-4121 Group Sales: +1-888-494-8863
6221 Willow Creek Ave., Des Moines, IA 50321 +1-888-389-4121 ~5.03 miles southwest of 50380
  • Two-star Airport hotel
  • 9 suites in hotel
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From$62
Very good 4.0 /5 Review Score Call BookMore Details
Quality Inn
+1-888-675-2083

How should we direct your call?

New Reservations: +1-888-675-2083 Group Sales: +1-888-494-8863
4950 NE 14th St., Des Moines, IA 50313 +1-888-675-2083 ~5.04 miles northeast of 50380
  • Affordable Highway property
  • 52 rooms in property
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From$57
Average 3.5 /5 Latest Reviews Call BookMore Details
Red Roof Inn Des Moines : 5020 NE 14th St.
+1-800-716-8490

How should we direct your call?

New Reservations: +1-800-716-8490 Group Sales: +1-888-494-8863
5020 NE 14th St., Des Moines, IA 50313 +1-800-716-8490 ~5.06 miles northeast of 50380
  • Economy Highway hotel
  • Free complimentary breakfast
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From$60
Poor 2.0 /5 Read Reviews Call BookMore Details
Motel 6 Des Moines, IA - North
+1-800-805-5223

How should we direct your call?

New Reservations: +1-800-805-5223 Group Sales: +1-888-494-8863
4940 NE 14th St., Des Moines, IA 50313 +1-800-805-5223 ~5.07 miles northeast of 50380
  • Low-priced property
  • Check in: 14:00
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From$60
Poor 2.5 /5 Guest Reviews Call BookMore Details
Sonesta Essential Des Moines
+1-888-965-1860

How should we direct your call?

New Reservations: +1-888-965-1860 Group Sales: +1-888-494-8863
4755 Merle Hay Rd., Des Moines, IA 50322 +1-888-965-1860 ~5.30 miles northwest of 50380
  • Low Cost Highway property
  • 12 suites in hotel
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From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Extended Stay America Select Suites - Des Moines - West Des Moine in West Des Moines
+1-888-788-5576

How should we direct your call?

New Reservations: +1-888-788-5576 Group Sales: +1-888-494-8863
2701 Westown Pkwy., West Des Moines, IA 50266 +1-888-788-5576 ~5.36 miles west of 50380
  • Cheap hotel
  • Fitness / Gym is on-site
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From$59
Average 3.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Des Moines Merle Hay : 4845 Merle Hay Rd.
+1-888-897-9207

How should we direct your call?

New Reservations: +1-888-897-9207 Group Sales: +1-888-494-8863
4845 Merle Hay Rd., Des Moines, IA 50322 +1-888-897-9207 ~5.38 miles northwest of 50380
  • 2 star Highway hotel
  • 76 rooms in property
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From$55
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Urbandale/Des Moines Area
+1-888-311-4278

How should we direct your call?

New Reservations: +1-888-311-4278 Group Sales: +1-888-494-8863
5900 Sutton Pl, Urbandale, IA 50322 +1-888-311-4278 ~5.49 miles northwest of 50380
  • Economy Suburban property
  • 3 suites in property
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From$45
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Hotel & Suites Des Moines Northwest An Ihg Hotel - Des Moines
+1-888-469-4795

How should we direct your call?

New Reservations: +1-888-469-4795 Group Sales: +1-888-494-8863
4800 Merle Hay Rd., Des Moines, IA 50322 +1-888-469-4795 ~5.51 miles northwest of 50380
  • Mid-scale Suburban property
  • 198 sleeping rooms in hotel
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From$89
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road
+1-888-734-9421

How should we direct your call?

New Reservations: +1-888-734-9421 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50310 +1-888-734-9421 ~5.52 miles northwest of 50380
  • Inexpensive property
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From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn & Suites Des Moines - Merle Hay Road in Des Moines
+1-888-841-5292

How should we direct your call?

New Reservations: +1-888-841-5292 Group Sales: +1-888-494-8863
4995 Merle Hay Rd., Des Moines, IA 50322 +1-888-841-5292 ~5.54 miles northwest of 50380
  • 3-star hotel
  • Hotel has 111 rooms
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From$62
Very good 4.0 /5 Read Reviews Call BookMore Details
Ramada by Wyndham Des Moines Tropics Resort & Conference Center
+1-888-455-5160

How should we direct your call?

New Reservations: +1-888-455-5160 Group Sales: +1-888-494-8863
5000 Merle Hay Rd., Des Moines, IA 50322 +1-888-455-5160 ~5.58 miles northwest of 50380
  • 3-star Suburban property
  • Hotel has 6 meeting rooms
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From$79
Average 3.0 /5 Guest Reviews Call BookMore Details
Americinn by Wyndham Johnston Des Moines in Johnston
+1-888-965-8297

How should we direct your call?

New Reservations: +1-888-965-8297 Group Sales: +1-888-494-8863
5050 Merle Hay Rd., Johnston, IA 50131 +1-888-965-8297 ~5.82 miles northwest of 50380
  • Cheap Highway hotel
  • Hotel has 2 floors
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From$64
Very good 4.0 /5 Recent Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Urbandale / Des Moines : 8711 Plum Dr.
+1-888-906-6358

How should we direct your call?

New Reservations: +1-888-906-6358 Group Sales: +1-888-494-8863
8711 Plum Dr., Urbandale, IA 50322 +1-888-906-6358 ~6.86 miles northwest of 50380
  • 2-star Highway hotel
  • Gym is available on property
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From$60
Average 3.0 /5 Reviews Call BookMore Details
Fairfield Inn & Suites Des Moines Urbandale
+1-888-749-6785

How should we direct your call?

New Reservations: +1-888-749-6785 Group Sales: +1-888-494-8863
8661 Plum Dr., Urbandale, IA 50322 +1-888-749-6785 ~6.87 miles northwest of 50380
  • Three Star Suburban hotel
  • Fitness center on property
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From$84
Very good 4.0 /5 Read Reviews Call BookMore Details
Grandstay Hotel & Suites : 6215 Merle Hay Rd.
+1-888-878-9982

How should we direct your call?

New Reservations: +1-888-878-9982 Group Sales: +1-888-494-8863
6215 Merle Hay Rd., Johnston, IA 50131 +1-888-878-9982 ~6.88 miles northwest of 50380
  • Two star Highway hotel
  • 76 rooms in hotel
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From$60
Average 3.0 /5 Read Reviews Call BookMore Details
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