Clayton Missouri Accommodations

Only hotels in Clayton are listed below. Explore our guide for inexpensive and discount hotel/motel rates in or near Clayton, MO for your upcoming individual or group travel. We provide the best Clayton Missouri hotel rooms. Review the Clayton hotel list below to find the perfect lodging. We also have a map of the Clayton hotels. Group booking? Search Clayton Group Hotel Discounts

The Clayton center point is around the area of Washington University in St.Louis.

Welcome to Clayton, Missouri, your art stop in the St. Louis region. Clayton is known for its galleries and boutiques as well as its family-friendly, laid-back pace within St. Louis County. You will find several art museums and parks here, as well as a few casinos. It's also close to Lindenwood University. More from this guide...

Clayton Hotels & Accommodations

The Ritz-Carlton, St. Louis
+1-888-389-4121
100 Carondelet Plaza, Clayton, MO 63105 +1-888-389-4121
  • High end Downtown hotel
  • Check-in time: 4:00pm
From£142
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Clayton Plaza Hotel & Extended Stay in St. Louis
+1-888-675-2083
7750 Carondelet, St. Louis, MO 63105 +1-888-675-2083 ~0.82 miles northwest of Clayton
  • Affordable Suburban hotel
  • 8 floors in property
From£86
Very good 4.0 /5 Recent Reviews Call BookMore Details
Charles F. Knight Executive Education & Conference Center in St. Louis
+1-800-716-8490
1 Brookings Dr. Campus Box1194, St. Louis, MO 63130 +1-800-716-8490 ~0.82 miles northeast of Clayton
  • Mid-scale Suburban property
  • Check in: 3:00 PM
From£78
Very good 4.5 /5 Latest Reviews Call BookMore Details
AC Hotel Clayton
+1-800-805-5223
227 South Central Ave., Clayton, MO 63105 +1-800-805-5223
  • 4-star Suburban property
  • Check in time: 4:00 PM
From£99
Average 3.0 /5 Guest Reviews Call BookMore Details
Seven Gables, St. Louis West, a Tribute Portfolio Hotel - Clayton
+1-888-965-1860
26 North Meramec Ave., Clayton, MO 63105 +1-888-965-1860
  • 4 star Suburban hotel
  • Check-in time: 3:00pm
From£59
Very good 4.0 /5 Latest Reviews Call BookMore Details
Courtyard Brentwood Marriott in Richmond Heights
+1-888-788-5576
8101 Dale Ave., Richmond Heights, MO 63117 +1-888-788-5576 ~1.08 miles southwest of Clayton
  • Midscale property
  • Check in: 15:00
From£159
Average 3.0 /5 Review Score Call BookMore Details
The Cheshire
+1-888-897-9207
6300 Clayton Rd., St. Louis, MO 63117 +1-888-897-9207 ~1.11 miles southeast of Clayton
  • High end Downtown property
  • 4 meeting rooms in property
From£86
Very good 4.0 /5 Review Score Call BookMore Details
Homewood Suites by Hilton St. Louis Galleria : 8040 Clayton Rd.
+1-888-311-4278
8040 Clayton Rd., Richmond Heights, MO 63117 +1-888-311-4278 ~1.16 miles west of Clayton
  • Midscale Suburban property
  • Check in: 3:00 PM
From£82
Average 3.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
+1-888-469-4795
216 North Meramec Ave., Clayton, MO 63105 +1-888-469-4795
  • Affordable Suburban property
  • Check in time: 15:00
From£71
Very good 4.5 /5 Review Score Call BookMore Details
Residence Inn by Marriott St. Louis Clayton : 8125 Forsyth Blvd.
+1-888-734-9421
8125 Forsyth Blvd., Clayton, MO 63105 +1-888-734-9421
  • Mid-scale Downtown property
  • Gym / Fitness Center Available
From£102
Average 3.0 /5 Reviews Call BookMore Details
Mainstay Suites St. Louis Galleria in Richmond Heights
+1-888-841-5292
8011 Galleria Pkwy., Richmond Heights, MO 63117 +1-888-841-5292 ~1.25 miles southwest of Clayton
  • Cheap Suburban property
  • 152 suites in property
From£47
Average 3.0 /5 Hotel Reviews Call BookMore Details
Springhill Suites St. Louis Brentwood : 1231 Strassner Dr.
+1-888-455-5160
1231 Strassner Dr., Brentwood, MO 63144 +1-888-455-5160 ~1.45 miles southwest of Clayton
  • 3 star Suburban hotel
  • Check-in time: 3:00pm
From£102
Very good 4.0 /5 Review Score Call BookMore Details
Towneplace Suites Brentwood
+1-888-965-8297
1695 South Hanley Rd., Brentwood, MO 63144 +1-888-965-8297 ~1.46 miles southwest of Clayton
  • 4-star Suburban hotel
  • Hotel has 128 suites
From£71
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Inn & Suites St. Louis Brentwood : 8700 Eager Rd.
+1-888-906-6358
8700 Eager Rd., Brentwood, MO 63144 +1-888-906-6358 ~1.46 miles southwest of Clayton
  • Mid-scale hotel
  • Check in: 3:00 PM
From£105
Average 3.0 /5 Recent Reviews Call BookMore Details
Moonrise Hotel : 6177 Delmar
+1-888-749-6785
6177 Delmar, St. Louis, MO 63112 +1-888-749-6785 ~1.62 miles northeast of Clayton
  • 4-star Downtown hotel
  • Hotel has 8 floors
From£118
Very good 4.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites St. Louis at Forest Park in St. Louis
+1-888-878-9982
5650 Oakland Ave., St. Louis, MO 63110 +1-888-878-9982 ~2.45 miles east of Clayton
  • 3-star Suburban hotel
  • Fitness / Gym is on-site
From£70
Very good 4.0 /5 Recent Reviews Call BookMore Details
Drury Inn & Suites St. Louis Near Forest Park : 2111 Sulphur Ave.
+1-888-389-4485
2111 Sulphur Ave., St. Louis, MO 63139 +1-888-389-4485 ~2.59 miles southeast of Clayton
  • Mid-scale Suburban property
  • Hotel has 164 rooms
From£89
Very good 4.5 /5 Read Reviews Call BookMore Details
Forest Park Hotel by Mdr - St. Louis
+1-888-389-4121
5915 Wilson Ave., St. Louis, MO 63110 +1-888-389-4121 ~2.63 miles southeast of Clayton
  • Cheap Suburban hotel
  • Check in: 3:00 PM
From£62
Average 3.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
+1-888-675-2083
5823 Wilson Ave., St. Louis, MO 63110 +1-888-675-2083 ~2.71 miles southeast of Clayton
  • Mid-scale Downtown hotel
The Royal Sonesta Chase Park Plaza St. Louis in St. Louis
+1-800-716-8490
212 Kingshighway Blvd., St. Louis, MO 63108 +1-800-716-8490 ~3.22 miles east of Clayton
  • Four star Downtown hotel
  • Check-in: 4:00 PM
From£119
Average 3.0 /5 Review Score Call BookMore Details
AC Hotel St. Louis in St. Louis
+1-800-805-5223
215 York Ave., St. Louis, MO 63108 +1-800-805-5223 ~3.29 miles east of Clayton
  • Mid-scale Downtown hotel
  • Check in time: 3:00PM
From£94
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express St. Louis Central West End An Ihg Hotel - St Louis
+1-888-965-1860
4630 Lindell, St Louis, MO 63108 +1-888-965-1860 ~3.39 miles east of Clayton
  • 3-star Downtown hotel
  • 3 suites in hotel
From£78
Average 3.0 /5 Review Score Call BookMore Details
Doubletree by Hilton St. Louis Forest Park : 4550 Forest Park Ave.
+1-888-788-5576
4550 Forest Park Ave., St. Louis, MO 63108 +1-888-788-5576 ~3.40 miles east of Clayton
  • Three Star hotel
  • 2 suites in property
From£78
Very good 4.0 /5 Review Score Call BookMore Details
Home2 Suites by Hilton St. Louis/Forest Park
+1-888-897-9207
920 South Taylor Ave., St. Louis, MO 63110 +1-888-897-9207 ~3.50 miles east of Clayton
  • Affordable Highway property
  • 8 suites in hotel
From£79
Average 3.0 /5 Reviews Call BookMore Details
Aloft St. Louis / Cortex
+1-888-311-4278
4245 Duncan Ave., St. Louis, MO 63110 +1-888-311-4278 ~3.92 miles east of Clayton
  • 3 star Downtown hotel
  • 129 sleeping rooms in hotel
From£63
Very good 4.0 /5 Guest Reviews Call BookMore Details
Cozysuites Lindell
+1-888-469-4795
4215 Lindell Blvd., St. Louis, MO 63108 +1-888-469-4795 ~4.03 miles east of Clayton
  • 3-star Downtown hotel
  • Hotel has 3 floors
From£63
Average 3.0 /5 Recent Reviews Call BookMore Details
Execustay at Piazza West Pine
+1-888-734-9421
3939 West Pine, St Louis, MO 63108 +1-888-734-9421 ~4.37 miles east of Clayton
  • Mid-scale hotel
  • 5 floors in property
From£71
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton St. Louis Frontenac in St. Louis
+1-888-841-5292
1335 South Lindbergh Blvd., St. Louis, MO 63131 +1-888-841-5292 ~4.46 miles west of Clayton
  • High-end Suburban hotel
  • Check-in: 3:00 PM
From£94
Very good 4.0 /5 Review Score Call BookMore Details
Element by Westin St. Louis / Midtown in St. Louis
+1-888-455-5160
3763 Forest Park Ave. St. Louis Mo 63108, St. Louis, MO 63108 +1-888-455-5160 ~4.51 miles east of Clayton
  • Midscale Downtown hotel
  • 153 suites in property
From£70
Very good 4.5 /5 Latest Reviews Call BookMore Details
Angad Arts Hotel
+1-888-965-8297
3550 Samuel Shepard Dr., St. Louis, MO 63103 +1-888-965-8297 ~5.01 miles east of Clayton
  • 4-star Downtown hotel
  • Hotel has 12 floors
From£75
Excellent 5.0 /5 Guest Reviews Call BookMore Details
Hilton Garden Inn St. Louis Airport : 4450 Evans Place Dr.
+1-888-906-6358
4450 Evans Place Dr., St. Louis, MO 63134 +1-888-906-6358 ~5.48 miles north of Clayton
  • Affordable Airport property
  • Shuttle to airport available
From£70
Very good 4.0 /5 Guest Reviews Call BookMore Details
Drury Inn St. Louis Airport
+1-888-749-6785
10490 Natural Bridge Rd., St. Louis, MO 63134 +1-888-749-6785 ~5.69 miles north of Clayton
  • Three Star Airport property
  • Fitness / Gym is on-site
From£82
Very good 4.0 /5 Recent Reviews Call BookMore Details
Residence Inn by Marriott St Louis Downtown : 525 South Jefferson Ave.
+1-888-878-9982
525 South Jefferson Ave., St. Louis, MO 63103 +1-888-878-9982 ~5.76 miles east of Clayton
  • 3 star Downtown property
  • 8 floors in hotel
From£63
Average 3.0 /5 Recent Reviews Call BookMore Details
Hotel Avyan : 2625 Lafayette Ave.
+1-888-389-4485
2625 Lafayette Ave., Saint Louis, MO 63104 +1-888-389-4485 ~5.79 miles east of Clayton
  • Economy Downtown property
  • 3 floors in hotel
From£46
Very good 4.0 /5 Read Reviews Call BookMore Details
Courtyard by Marriott St. Louis Downtown West - St. Louis
+1-888-389-4121
2340 Market St., St. Louis, MO 63103 +1-888-389-4121 ~5.90 miles east of Clayton
  • 3-star property
From£58
Very good 4.0 /5 Review Score Call BookMore Details
St. Louis Airport Hotel - St. Louis
+1-888-675-2083
9600 Natural Bridge Rd., St. Louis, MO 63134 +1-888-675-2083 ~5.97 miles north of Clayton
  • Three Star Airport property
  • Hotel has 7 floors
From£38
Very good 4.0 /5 Reviews Call BookMore Details
Travelodge by Wyndham St. Louis - Berkeley
+1-800-716-8490
9645 Natural Bridge Rd., Berkeley, MO 63134 +1-800-716-8490 ~6.04 miles north of Clayton
  • Economy hotel
  • Check in: 3:00 PM
From£47
Average 3.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham St. Louis Airport
+1-800-805-5223
9798 St. Charles Rock Rd., Breckenridge Hills, MO 63114 +1-800-805-5223 ~6.04 miles northwest of Clayton
  • Two-star Airport hotel
  • 2 floors in property
The Pear Tree Inn Near Union Station
+1-888-965-1860
2211 Market St., St Louis, MO 63103 +1-888-965-1860 ~6.06 miles east of Clayton
  • 3 star Downtown property
  • 11 floors in hotel
From£71
Very good 4.0 /5 Review Score Call BookMore Details
Fairfield Inn N Stes Marriott in St Louis
+1-888-788-5576
2144 Market St., St Louis, MO 63103 +1-888-788-5576 ~6.08 miles east of Clayton
  • Affordable property
  • Hotel has 5 floors
From£71
Average 3.0 /5 Hotel Reviews Call BookMore Details
Drury Inn St. Louis Union Station : 201 South 20th St.
+1-888-897-9207
201 South 20th St., St. Louis, MO 63103 +1-888-897-9207 ~6.21 miles east of Clayton
  • 3-star Downtown hotel
  • Fitness + Health Center
From£82
Very good 4.5 /5 Reviews Call BookMore Details
Renaissance St. Louis Airport Hotel : 9801 Natural Bridge Rd.
+1-888-311-4278
9801 Natural Bridge Rd., St Louis, MO 63134 +1-888-311-4278 ~6.29 miles north of Clayton
  • Four star Airport hotel
  • 393 rooms in property
From£67
Very good 4.0 /5 Review Score Call BookMore Details
St. Louis Union Station Hotel, Curio Collection by Hilton - St Louis
+1-888-469-4795
1820 Market St., St Louis, MO 63103 +1-888-469-4795 ~6.33 miles east of Clayton
  • High end Downtown hotel
  • 6 floors in property
From£70
Very good 4.0 /5 Latest Reviews Call BookMore Details
Super 8 by Wyndham St. Louis North : 6200 North Broadway
+1-888-734-9421
6200 North Broadway, St. Louis, MO 63147 +1-888-734-9421 ~6.39 miles east of Clayton
  • Low-priced property
  • Check-in time: 15:00
From£47
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express & Suites St Louis Airport, an IHG Hotel
+1-888-841-5292
10000 Natural Bridge Rd., St. Louis, MO 63134 +1-888-841-5292 ~6.42 miles north of Clayton
  • Low priced Airport property
  • Fitness + Health Center
From£75
Very good 4.0 /5 Review Score Call BookMore Details
Doubletree by Hilton St. Louis Airport
+1-888-455-5160
4505 Woodson Rd., St. Louis, MO 63134 +1-888-455-5160 ~6.55 miles north of Clayton
  • Affordable Airport hotel
  • Hotel has 5 floors
From£63
Average 3.0 /5 Read Reviews Call BookMore Details
Oyo Hotel St. Louis Lambert Airport - St. Louis
+1-888-965-8297
4545 Woodson Rd., St. Louis, MO 63134 +1-888-965-8297 ~6.58 miles north of Clayton
  • Economical Airport property
  • Check-in time: 3.00PM
Best Western Plus St. Louis Airport Hotel : 4576 Woodson Rd.
+1-888-906-6358
4576 Woodson Rd., Saint Louis, MO 63134 +1-888-906-6358 ~6.60 miles north of Clayton
  • Midscale Airport hotel
  • Check in time: 03:00pm
From£51
Average 3.0 /5 Guest Reviews Call BookMore Details
Quality Inn St. Louis Airport Hotel in St Louis
+1-888-749-6785
10232 Natural Bridge Rd., St Louis, MO 63134 Website +1-888-749-6785 ~6.65 miles north of Clayton
  • Low Cost Airport property
  • Hotel has 4 suites
From£40
Poor 2.0 /5 Read Reviews Call BookMore Details
Oyo Hotel St. Louis Downtown City Center Mo - St. Louis
+1-888-878-9982
400 South 14th St. St. Louis Mo 63103, St. Louis, MO 63101 +1-888-878-9982 ~6.67 miles east of Clayton
  • Three Star Downtown property
  • 144 suites in hotel
From£63
Average 3.0 /5 Read Reviews Call BookMore Details

Next: See My Clayton Hotels with Pricing

What is the best time to visit Clayton, MO?

As with most temperate climates, the best time of year to visit depends on what you want to do. Come in the summer to experience some of the local parks or in the winter to see the lights. There is the nearby St. Louis Art Fair that attracts many visitors each year. In the fall, you can also check out The Big Read, which is an annual literary festival.

What are the best discounts on hotels in Clayton, MO?

The Ritz Carlton offers AAA discounts to members, so if you're part of the club, you can enjoy fine amenities at a fraction of the cost. There are also discounts available at the Charles F Knight Executive Education Center, The Parkway Hotel, and River City Casino & Hotel, and Moonrise Hotel if you are an AAA member. The Rodeway Inn Saint Charles, Hotel Ignacio, and Hollywood Casino Hotel St Louis all offer discounts for senior citizens.

What are the best value hotel options in Clayton, MO?

Clayton Plaza Hotel is one of the best midrange options available in Clayton. You will find a 24-hour gym, a fitness center, free breakfast buffet, and an outdoor pool in this hotel that's conveniently located to downtown.

Moonrise Hotel is a good, mid-range hotel that was recently built in 2009. Their bathrooms are a feature if you prefer rainfall showerheads, and they offer designer toiletries at no cost. Enjoy a good workout in their gym, and then get breakfast made to order for a reasonable fee.

Parkway Hotel is another option to consider if you are interested in history or science. One of the best features of this hotel is that it's located within walking distance of two interesting attractions: The St Louis Science Center and the Cathedral Basilica of St. Louis. As for the hotel itself, take a look at its well-manicured rooms and lounge that resemble a much more expensive hotel. Guests appreciate the cleanliness of the rooms and the central location of the hotel.

A mid-range hotel with access to casinos is the River City Casino & Hotel. This hotel does not lack for entertainment options. The most obvious choice would be the on-site casino. You also have five different restaurants to choose from. There is also a nightclub on the property. If you want to venture out for an evening of your stay, the hotel is within walking distance of several parks and a river walk.

A second option for casino lovers would be the Hollywood Casino & Hotel. This is a large, 502-room hotel with a casino and a nightclub. It has seven restaurants and 3 bars to choose from, so you don't have to leave the premises if you don't want to. If you are in town for business at the Lindenwood University or the Scottrade Center, you will be happy to note that this hotel is in close proximity to both. The hotel also has its own 6400 square foot event space that is available for weddings, conferences, and other events.

If you are coming with a group, a popular option is the Pere Marquette Lodge & Conference Center. The attached conference center is a convenience for group meetings. The lodge has an indoor pool and spa for evening enjoyment. You can also get to Raging Rivers Waterpark quickly. The rustic lodge facade of the building is charming, while the beds and amenities are clean and well-maintained. The hotel is welcoming to families, large groups, couples, and solo travelers alike.

Embassy Suites is a good hotel option if you are looking to mix with other travelers. They hold a reception every day so that guests can meet one another (and maybe go explore the city together). Their rooms also feature a shower/tub combination if you need to unwind after a long day of being out and about. While you are in the area, check out the Lewis & Clark Boathouse and Nature Center or go for a stroll and look at some of the historic buildings on the Lindenwood University campus.

What are the things to do in Clayton, MO?

The best thing to do on your visit to Clayton is get away from the bustle of city life. You can explore some of the art galleries and stores, such as Sasha's Wine Bar or the "How Sweet Is This" Itsy Bitsy Candy Shoppe. You can also check out the Historic Hanley house on a day of your visit.

Some of the best attractions in St Louis County are actually located in or around Clayton. The St Louis Zoo is a favorite for kids of all ages. You can also take a look at the free St Louis Art Museum. They house over 30,000 paintings, sculptures, and other works of art. Grand Basin and the Art Hill are also located nearby. On a nice day, you can take in these sights with a walk along the Art Hill, followed by a stop into some of the nearby museums.

Outdoor days are also great for a visit to Shaw Park. This is a large park in the center of Clayton with plenty of open space and playgrounds for the kids. The Paul C Wehner Senior Memorial Park is another outdoor attraction of note. Lewis Park, Taylor Park, and Hanley Park are a few other parks that come to mind.

And, if you start craving the action again, St. Louis proper is only a stone's throw away. All in all, you should be looking forward to a comfortable visit to Clayton, MO.

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