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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels, Motels & Accommodations

Super 8 by Wyndham Charleston/Sikeston East MO in Charleston
+1-888-389-4121
310 South Story, Charleston, MO 63834
  • Low priced Highway property
  • Check in time: 3:00pm
From£33
Average 3.5 /5 Hotel Reviews Call BookMore Details
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Quality Inn Charleston - Sikeston : 102 Drake St.
+1-888-675-2083
102 Drake St., Charleston, MO 63834
  • Cheap Highway property
  • 40 sleeping rooms in hotel
From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 Sikeston Mo - SIKESTON
+1-800-716-8490
110 South Interstate Dr., SIKESTON, MO 63801 ~11.02 miles west of Charleston
  • Low-priced hotel
From£48
Average 3.0 /5 Read Reviews Call BookMore Details
Best Western Plus Sikeston
+1-800-805-5223
120 South Interstate Dr., Sikeston, MO 63801 ~11.05 miles west of Charleston
  • Low-priced Highway property
  • Hotel has 2 floors
From£34
Very good 4.0 /5 Read Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston in Sikeston
+1-888-965-1860
220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Two-star hotel
From£48
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn Cairo I-57 in Cairo
+1-888-788-5576
13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • Mid-scale Highway hotel
  • Check-in: 3 pm
Super 8 by Wyndham Sikeston/Miner Area
+1-888-897-9207
2609 East Malone, Sikeston, MO 63801 ~11.36 miles west of Charleston
  • Two-star Convention Center property
  • Check in time: 01:00
From£48
Average 3.0 /5 Hotel Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) in Sikeston
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • 3 star Highway hotel
  • Hotel has 2 floors
From£64
Very good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn
+1-888-469-4795
109 Matthews Lane, Sikeston, MO 63801 ~11.40 miles west of Charleston
  • Midscale Highway property
  • Check in: 11:00
From£68
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Inn & Suites Sikeston
+1-888-734-9421
2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • 3-star Highway hotel
  • Check-in: 3:00 PM
From£83
Very good 4.5 /5 Recent Reviews Call BookMore Details
Pear Tree Inn Sikeston
+1-888-841-5292
2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Suburban hotel
  • 80 rooms in hotel
From£64
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Sikeston : 1240 Commerce Dr.
+1-888-455-5160
1240 Commerce Dr., Sikeston, MO 63801 ~14.31 miles west of Charleston
  • 3-star Rural property
  • 4 floors in hotel
From£64
Average 3.0 /5 Read Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel
+1-888-965-8297
115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • 3 star Rural property
  • Check-in time: 3:00pm
From£64
Average 3.0 /5 Review Score Call BookMore Details
Americas Best Value Inn Ullin Mounds in Ullin
+1-888-906-6358
128 Cheekwood Lane, Ullin, IL 62992 ~25.98 miles north of Charleston
  • Low priced hotel
  • Hotel has 2 floors
From£48
Average 3.0 /5 Guest Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown : 400 Broadway St.
+1-888-749-6785
400 Broadway St., Cape Girardeau, MO 63701 ~28.56 miles north of Charleston
  • 3-star Downtown property
  • Gym is available on property
From£64
Very good 4.0 /5 Latest Reviews Call BookMore Details
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Candlewood Suites Cape Girardeau, an IHG Hotel : 485 South Mount Auburn Rd.
+1-888-878-9982
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • Low Cost Highway property
  • 4 floors in hotel
From£55
Very good 4.0 /5 Read Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East in Cape Girardeau
+1-888-389-4485
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~29.33 miles northwest of Charleston
  • Midscale Highway hotel
  • Hotel has 86 rooms
From£64
Excellent 5.0 /5 Review Score Call BookMore Details
Victorian Inn & Suites : 3256 William St.
+1-888-389-4121
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • Three Star Golf Course hotel
  • Comp. Breakfast
From£63
Average 3.0 /5 Reviews Call BookMore Details
Auburn Place Hotel & Suites
+1-888-675-2083
3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • Mid-scale Highway hotel
  • Fitness center on property
From£46
Very good 4.5 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55 in Cape Girardeau
+1-800-716-8490
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • Three Star property
  • 102 suites in hotel
From£64
Very good 4.5 /5 Latest Reviews Call BookMore Details
Fairfield Inn & Suites Cape Girardeau
+1-800-805-5223
433 Cape West Crossing, Cape Girardeay, MO 63703 ~29.46 miles northwest of Charleston
  • 3 star hotel
From£64
Average 3.0 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau West
+1-888-965-1860
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~29.49 miles northwest of Charleston
  • Cheap hotel
  • Hotel has 3 floors
From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center - Cape Girardeau
+1-888-788-5576
3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • Two star Highway property
  • Hotel has 78 rooms
From£53
Very good 4.0 /5 Review Score Call BookMore Details
Drury Suites Cape Girardeau - Cape Girardeau
+1-888-897-9207
3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • Three Star Highway hotel
  • Check-in: 3:00 PM
From£68
Very good 4.5 /5 Read Reviews Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-311-4278
3351 Percy Dr., Cape Girardeau, MO 63701 ~29.76 miles northwest of Charleston
  • Three Star property
  • 168 rooms in property
From£47
Average 3.0 /5 Review Score Call BookMore Details
Drury Lodge
+1-888-469-4795
104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.77 miles northwest of Charleston
  • Mid-scale Highway property
  • Check-in: 3:00pm
From£64
Average 3.0 /5 Latest Reviews Call BookMore Details
Travel Inn
+1-888-734-9421
301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Low priced Highway property
  • Check in: 3:00 PM
Travel Inn - Martson
+1-888-841-5292
301 State Highway Ad, Martson, MO 63866 ~31.46 miles southwest of Charleston
  • 2-star property
From£48
Poor 2.5 /5 Review Score Call BookMore Details
Red Roof Inn Marston
+1-888-455-5160
501 South Outer Rd., Marston, MO 63866 ~31.61 miles southwest of Charleston
  • 2-star hotel
  • 63 sleeping rooms in hotel
From£48
Average 3.0 /5 Hotel Reviews Call BookMore Details
Quality Inn - Cape Girardeau
+1-888-965-8297
2011 North Kingshighway St., Cape Girardeau, MO 63701 Website ~31.73 miles northwest of Charleston
  • Two-star property
  • Check in time: 3:00 PM
From£48
Very good 4.0 /5 Latest Reviews Call BookMore Details
TRU by Hilton Cape Girardeau - Cape Girardeau
+1-888-906-6358
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 ~32.92 miles northwest of Charleston
  • 3-star Riverfront hotel
  • Check-in: 3:00 pm
From£64
Average 3.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau
+1-888-749-6785
3003 South Old Orchard Rd., Jackson, MO 63755 ~33.46 miles northwest of Charleston
  • Affordable Highway hotel
  • Check-in time: 03:00
From£68
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau - Jackson
+1-888-878-9982
2904 Old Orchard Rd., Jackson, MO 63755 Website ~33.57 miles northwest of Charleston
  • Mid-scale Highway hotel
  • 3 floors in hotel
From£52
Average 3.0 /5 Review Score Call BookMore Details
Comfort Suites : 2904 Old Orchard Rd.
+1-888-389-4485
2904 Old Orchard Rd., Jackson, 63755 United States ~33.57 miles northwest of Charleston
  • High end Highway property
  • Fitness / Gym is on-site
From£100
Average 3.0 /5 Review Score Call BookMore Details
Residence Inn by Marriott Paducah - Paducah
+1-888-389-4121
3900 Coleman Crossing Circle, Paducah, KY 42001 ~34.97 miles east of Charleston
  • 3 star Suburban property
  • Hotel has 2 meeting rooms
From£71
Very good 4.0 /5 Reviews Call BookMore Details
Pear Tree Inn Paducah : 5006 Hinkleville Rd.
+1-888-675-2083
5006 Hinkleville Rd., Paducah, KY 42001 ~35.47 miles east of Charleston
  • 2 star Suburban hotel
  • Free comp. breakfast
From£44
Very good 4.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Dexter in Dexter
+1-800-716-8490
913 Outer Rd., Dexter, MO 63841 ~36.12 miles west of Charleston
  • 2-star hotel
  • Check-in time: 11:00
From£48
Average 3.0 /5 Latest Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino : 100 East Front St.
+1-800-805-5223
100 East Front St., Metropolis, IL 62960 ~36.52 miles east of Charleston
  • 4 star property
  • Check in time: 16:00
From£129
Very good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Metropolis : 203 East Front St.
+1-888-965-1860
203 East Front St., Metropolis, IL 62960 ~36.55 miles east of Charleston
  • Low Cost Riverfront hotel
  • 2 floors in property
From£36
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sleep Inn & Mainstay Suites - Union City
+1-888-788-5576
1111 Blue Heron Lane, Union City, TN 38261 ~36.64 miles southeast of Charleston
  • Cheap Rural property
  • Check-in: 15:00
From£48
Average 3.0 /5 Reviews Call BookMore Details
Travelodge by Wyndham Dexter : 1608 West Business U.s. 60
+1-888-897-9207
1608 West Business U.s. 60, Dexter, MO 63841 ~36.87 miles west of Charleston
  • Midscale hotel
From£54
Very good 4.0 /5 Read Reviews Call BookMore Details
 Econo Lodge Paducah West I-24 : 5120 Hinkleville Rd.
+1-888-311-4278
5120 Hinkleville Rd., Paducah, KY 42001 ~37.23 miles east of Charleston
  • Low-priced Airport property
  • Hotel has an eco-friendly policy See policy
From£48
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Suites Paducah in Paducah
+1-888-469-4795
2930 James Sanders Blvd., Paducah, KY 42001 ~37.34 miles east of Charleston
  • 3 star Suburban property
  • 120 suites in hotel
From£79
Very good 4.0 /5 Read Reviews Call BookMore Details
Quality Suites Paducah I-24
+1-888-734-9421
2880 James Sanders Blvd., Paducah, KY 42001 Website ~37.41 miles east of Charleston
  • Inexpensive Highway hotel
  • Check in time: 3:00 pm
From£48
Average 3.0 /5 Recent Reviews Call BookMore Details
Sleep Inn Union City
+1-888-841-5292
1111b Blue Heron Lane, Union City, TN 38261 ~37.44 miles southeast of Charleston
  • Two-star Rural property
  • 3 floors in hotel
From£62
Very good 4.0 /5 Recent Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags in Lithia Springs
+1-888-455-5160
960 West Pointe Court, Lithia Springs, GA 30122 Website ~37.46 miles east of Charleston
  • Affordable Downtown property
  • Check in: 3:00pm
From£56
Very good 4.0 /5 Read Reviews Call BookMore Details
Country Inn & Suites by Radisson, Paducah, KY
+1-888-965-8297
145 Mcbride Lane, Paducah, KY 42001 ~37.46 miles east of Charleston
  • Affordable Highway hotel
  • Hotel has 3 floors
From£39
Very good 4.0 /5 Reviews Call BookMore Details
Baymont by Wyndham Paducah
+1-888-906-6358
5300 Old Cairo Rd., Paducah, KY 42001 ~37.50 miles east of Charleston
  • Affordable hotel
  • 3 floors in property
Hotel 7 Inn : 5001 Hinkleville Rd.
+1-888-749-6785
5001 Hinkleville Rd., Paducah, KY 42001 ~37.51 miles east of Charleston
  • Low-priced hotel
From£48
Average 3.0 /5 Read Reviews Call BookMore Details
Econo Lodge
+1-888-878-9982
1415 East 5th St., Metropolis, IL 62960 ~37.60 miles east of Charleston
  • Low-priced hotel
  • 45 rooms in hotel
From£48
Terrible 1.0 /5 Latest Reviews Call BookMore Details

Next: See My Charleston Hotels with Pricing

Graph of Charleston, MO Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Charleston, MO discounts available. The chart reflects the cheapest Charleston hotel for each day and each star rating category.

FAQs about hotels in Charleston

What are the most favored hotels in Charleston?

Hampton Inn Cape Girardeau I 55 East, Drury Inn & Suites Sikeston and Auburn Place Hotel & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Charleston?

Comfort Suites, Harrah's Metropolis Hotel & Casino and Quality Inn Cairo I-57 are the top 3 luxury hotels near Charleston city center.

What hotels are closest to the city center of Charleston?

Super 8 by Wyndham Charleston, Quality Inn Charleston - Sikeston, and Motel 6 Sikeston Mo are the properties closest to Charleston city center.

What are the best independent hotels in Charleston?

Auburn Place Hotel & Suites, Drury Suites Cape Girardeau and Travel Inn & Suites - Sikeston are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Charleston?

Courtyard by Marriott Cape Girardeau Downtown, Residence Inn by Marriott Paducah and Fairfield Inn & Suites Cape Girardeau are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Charleston?

Quality Inn, Sleep Inn Union City and Comfort Inn & Suites near Six Flags are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Charleston?

Holiday Inn Express & Suites Cape Girardeau I 55, Candlewood Suites Cape Girardeau, an IHG Hotel and Holiday Inn Express & Suites Sikeston An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Recent traveler reviews of Charleston, MO

Below are reviews of the city of Charleston, MO from an actual visitor's perspective.

"Easily Accessible"
Score 5.0 / 5

Easily accessible.

Mamon T., from 07-Dec-2023
The average traveler rating of the city of Charleston, MO shown above is 5.0 out of 5 based on 1 reviews
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