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Lake City South Carolina Accommodations

Find the perfect hotel in Lake City using our hotel guide provided below. Find discounted hotel accommodations in or close to Lake City, SC for your personal leisure or group travel. Discover the most favored Lake City South Carolina hotel/motel rooms. Review the Lake City hotel list below to find the perfect lodging. We also have a map of the Lake City hotels. Coordinating a group? Get Lake City Group Hotel Rates

The Lake City center is approximately 12 miles northeast of Williamsburg County Airport and 14 miles north of Kingstree Amtrak Station.

Lake City Hotels, Motels & Accommodations

Inn at the Crossroads
+1-888-389-4121
128 West Main St., Lake City, SC 29560
  • Inexpensive Downtown property
  • 3 meeting rooms in hotel
From£86
Very good 4.0 /5 Read Reviews Call BookMore Details
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Days Inn by Wyndham Lake City
+1-888-675-2083
170 South Ron Mcnair Blvd., Lake City, SC 29560
  • Economy Downtown hotel
  • Check in time: 02.00 PM
From£47
Average 3.5 /5 Reviews Call BookMore Details
Quality Inn & Suites : 202 North Ron Mcnair Blvd.
+1-800-716-8490
202 North Ron Mcnair Blvd., Lake City, SC 29560
  • 3 star hotel
  • 56 rooms in hotel
From£63
Very good 4.0 /5 Guest Reviews Call BookMore Details
Quality Inn
+1-800-805-5223
1610 North Longstreet St., Kingstree, SC 29556 ~13.47 miles south of Lake City
  • Affordable Highway hotel
  • Check in time: 15:00
From£63
Very good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Turbeville - Gable
+1-888-965-1860
7835 Myrtle Beach Highway, Gable, SC 29051 ~20.05 miles west of Lake City
  • Low Cost hotel
From£47
Poor 2.0 /5 Review Score Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 in Florence
+1-888-788-5576
3783a West Palmetto St., Florence, SC 29501 ~21.41 miles north of Lake City
  • Cheap Highway property
  • Comp. Breakfast
From£45
Terrible 1.0 /5 Hotel Reviews Call BookMore Details
Days Inn Florence : 3783 West Palmetto St. I 95
+1-888-897-9207
3783 West Palmetto St. I 95, Florence, SC 29501 ~21.42 miles north of Lake City
  • Economical Highway property
  • Free comp. breakfast
Travelodge by Wyndham Florence in Florence
+1-888-311-4278
1084 Oregon Coast Highway, Florence, OR 97439 ~21.49 miles north of Lake City
  • Low Cost property
From£78
Average 3.0 /5 Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 - Florence
+1-888-469-4795
3783a West Palmetto St., Florence, SC 29502 ~21.49 miles north of Lake City
  • Low Cost Highway hotel
  • Check-in time: 11:00 AM
From£47
Terrible 1.0 /5 Reviews Call BookMore Details
Comfort Inn & Suites Florence : 527 Woody Jones Blvd.
+1-888-734-9421
527 Woody Jones Blvd., Sc 554, SC 29501 ~22.63 miles north of Lake City
  • 3 star Suburban property
  • 3 floors in hotel
From£63
Very good 4.5 /5 Review Score Call BookMore Details
Fairfield Inn & Suites by Marriott Florence I-20 - Florence
+1-888-841-5292
501 Woody Jones Blvd., Florence, SC 29501 ~22.66 miles north of Lake City
  • 3 star Convention Center hotel
  • Comp. Breakfast
From£78
Average 3.0 /5 Hotel Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC
+1-888-455-5160
900 Woody Jones Blvd., Florence, SC 29501 ~22.71 miles north of Lake City
  • Affordable Convention Center property
  • Has environment-friendly policy See more
From£70
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Towneplace Suites by Marriott Florence : 2650 Hospitality Blvd.
+1-888-965-8297
2650 Hospitality Blvd., Florence, SC 29501 ~22.79 miles north of Lake City
  • Midscale Suburban hotel
  • 89 suites in hotel
From£74
Very good 4.0 /5 Latest Reviews Call BookMore Details
Springhill Suites : 2670 Hospitality Blvd.
+1-888-906-6358
2670 Hospitality Blvd., Florence, SC 29501 ~22.80 miles north of Lake City
  • Three Star Convention Center hotel
  • Check in: 4:00pm
From£63
Average 3.0 /5 Hotel Reviews Call BookMore Details
Accident : Florence Sc Usa
+1-888-749-6785
Florence Sc Usa, Florence, SC 29464 ~22.83 miles north of Lake City
  • Three Star hotel
From£243
Average 3.0 /5 Recent Reviews Call BookMore Details
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Residence Inn Marriott Florence : 2660 Hospitality Blvd.
+1-888-878-9982
2660 Hospitality Blvd., Florence, SC 29501 ~22.85 miles north of Lake City
  • Midscale Suburban hotel
  • 94 suites in property
From£74
Very good 4.0 /5 Reviews Call BookMore Details
Staybridge Suites - Florence
+1-888-389-4485
150 Westpark Dr., Florence, SC 29501 ~22.87 miles north of Lake City
  • 3-star Convention Center hotel
  • Hotel has 112 rooms
From£105
Very good 4.0 /5 Guest Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH : 3440 West Radio Dr.
+1-888-389-4121
3440 West Radio Dr., Florence, SC 29501 ~22.87 miles north of Lake City
  • Three Star Convention Center hotel
  • Check-in: 3:00 PM
From£75
Very good 4.0 /5 Latest Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center : 2690 David Mcleod Blvd.
+1-888-675-2083
2690 David Mcleod Blvd., Florence, SC 29501 ~22.89 miles north of Lake City
  • Luxury Five Star Highway property
  • 2 floors in hotel
From£48
Average 3.0 /5 Latest Reviews Call BookMore Details
Hyatt Place Florence Downtown in Florence
+1-800-716-8490
100 East Evans St., Florence, SC 29501 ~22.96 miles north of Lake City
  • Affordable Downtown property
  • Has environment-friendly policy See more
From£98
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hotel Florence, Tapestry Collection by Hilton
+1-800-805-5223
126 West Evans St., Florence, SC 29501 ~22.97 miles north of Lake City
  • Mid-scale Downtown hotel
  • Check in time: 4:00pm
From£90
Very good 4.0 /5 Reviews Call BookMore Details
Homewood Suites by Hilton Florence in Florence
+1-888-965-1860
3450 West Radio Dr., Florence, SC 29501 ~22.98 miles north of Lake City
  • 3-star Convention Center hotel
  • 5 floors in hotel
From£63
Very good 4.5 /5 Hotel Reviews Call BookMore Details
Courtyard by Marriott Florence
+1-888-788-5576
2680 Hospitality Blvd., Florence, SC 29501 ~22.99 miles north of Lake City
  • 3 star Convention Center hotel
  • 90 rooms in hotel
From£78
Average 3.0 /5 Latest Reviews Call BookMore Details
Hilton Garden Inn : 2671 Hospitality Blvd.
+1-888-897-9207
2671 Hospitality Blvd., Florence, SC 29501 ~23.00 miles north of Lake City
  • Mid-scale Highway property
  • 2 meeting rooms in property
From£86
Very good 4.0 /5 Guest Reviews Call BookMore Details
Hampton Inn & Suites Florence Center
+1-888-311-4278
3000 West Radio Dr., Florence, SC 29501 ~23.14 miles north of Lake City
  • Three Star Convention Center hotel
  • 82 sleeping rooms in hotel
From£86
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center
+1-888-469-4795
140 Dunbarton Dr., Florence, SC 29501 ~23.21 miles north of Lake City
  • Cheap Convention Center hotel
  • Check in: 3:00pm
From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Quality Inn & Suites Civic Center - Florence
+1-888-734-9421
150 Dunbarton Dr., Florence, SC 29501 ~23.24 miles north of Lake City
  • 2 star Highway property
  • Hotel has 15 suites
From£47
Average 3.0 /5 Review Score Call BookMore Details
Rodeway Inn & Suites in Florence
+1-888-841-5292
181 West Lucas St., Florence, SC 29501 ~23.50 miles north of Lake City
  • Economy property
  • Free breakfast available
From£47
Average 3.0 /5 Recent Reviews Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327, an I : 2101 Florence Harllee Blvd.
+1-888-455-5160
2101 Florence Harllee Blvd., Florence, SC 29506 ~23.79 miles north of Lake City
  • Mid-scale Suburban hotel
  • 86 rooms in property
From£74
Very good 4.0 /5 Read Reviews Call BookMore Details
Best Western Inn in Florence
+1-888-965-8297
1808 West Lucas St., Florence, SC 29501 ~25.09 miles north of Lake City
  • Economy Highway property
  • Complimentary breakfast is offered
From£46
Average 3.5 /5 Latest Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham
+1-888-906-6358
1826 West Lucas St., Florence, SC 29501 ~25.11 miles north of Lake City
  • Two star Highway hotel
  • 112 rooms in hotel
Super 8 by Wyndham Florence
+1-888-749-6785
1832 1 / 2 Lucas St., Florence, SC 29501 ~25.13 miles north of Lake City
  • Cheap Highway property
From£47
Average 3.0 /5 Reviews Call BookMore Details
Knights Inn Florence - Florence
+1-888-878-9982
1834 West Lucas St., Florence, SC 29501 ~25.17 miles north of Lake City
  • Two star hotel
  • Hotel has 109 rooms
From£39
Poor 2.0 /5 Read Reviews Call BookMore Details
Fairview Inn Florence in Florence
+1-888-389-4485
1811 West Lucas St., Florence, SC 29501 ~25.21 miles north of Lake City
  • Economical Highway property
  • Free breakfast
From£31
Poor 2.0 /5 Review Score Call BookMore Details
Clarion Inn & Suites
+1-888-389-4121
1819 Building a West Lucas St., Florence, SC 29501 ~25.33 miles north of Lake City
  • Mid-scale Highway hotel
  • Free breakfast available
From£63
Average 3.0 /5 Recent Reviews Call BookMore Details
Mainstay Suites Florence Sc
+1-888-675-2083
1819 West Lucas St. Building B, Florence, SC 29501 ~25.33 miles north of Lake City
  • 2-star Highway property
  • Fitness / Gym is on-site
From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 Florence, SC
+1-800-716-8490
2004 West Lucas St., Florence, SC 29501 ~25.36 miles north of Lake City
  • 2 star Downtown hotel
From£47
Average 3.0 /5 Read Reviews Call BookMore Details
Park Inn by Radisson Florence Sc - Florence
+1-800-805-5223
1729 Mandeville Rd., Florence, SC 27407 ~25.39 miles north of Lake City
  • Midscale hotel
  • Check in: 15:00
From£71
Very good 4.0 /5 Guest Reviews Call BookMore Details
Park Inn by Radisson : 1729 Mandeville Rd.
+1-888-965-1860
1729 Mandeville Rd., Florence, SC 29501 ~25.39 miles north of Lake City
  • Inexpensive Highway hotel
  • Fitness / Gym is on-site
From£59
Average 3.0 /5 Guest Reviews Call BookMore Details
Country Inn & Suites by Radisson, Florence, SC : 1739 Mandeville Rd.
+1-888-788-5576
1739 Mandeville Rd., Florence, SC 29501 ~25.43 miles north of Lake City
  • Mid-scale Highway hotel
  • 3 floors in property
From£62
Very good 4.0 /5 Review Score Call BookMore Details
Suburban Studios Florence I-95 in Florence
+1-888-897-9207
1914 West Lucas St., Florence, SC 29501 ~25.48 miles north of Lake City
  • Two-star Highway hotel
  • Hotel has 167 rooms
Howard Johnson by Wyndham Florence - Florence
+1-888-311-4278
2038 West Lucas St., Florence, SC 29501 ~25.49 miles north of Lake City
  • Low priced Highway hotel
  • Hotel has 2 floors
Hampton Inn & Suites Florence North
+1-888-469-4795
1735 Stokes Rd., Florence, SC 29501 ~25.50 miles north of Lake City
  • Low-priced Highway property
  • 136 sleeping rooms in hotel
From£82
Very good 4.0 /5 Reviews Call BookMore Details
Days Inn by Wyndham Florence / I 95 North - Florence
+1-888-734-9421
2111 West Lucas, Florence, SC 29501 ~25.61 miles north of Lake City
  • Low priced Highway hotel
  • Check-in: 2pm
From£39
Average 3.5 /5 Reviews Call BookMore Details
Comfort Suites Florence I-95 - Florence
+1-888-841-5292
2120 West Lucas St., Florence, SC 29501 ~25.65 miles north of Lake City
  • Midscale Highway hotel
  • Comp. Breakfast
From£63
Very good 4.0 /5 Latest Reviews Call BookMore Details
TRU by Hilton Florence I 95 in Florence
+1-888-455-5160
2140 West Lucas St., Florence, SC 29501 ~25.70 miles north of Lake City
  • Midscale hotel
  • Hotel has 5 floors
From£63
Very good 4.0 /5 Guest Reviews Call BookMore Details
Sleep Inn Florence North in Florence
+1-888-965-8297
1833 Florence Park Dr., Florence, SC 29501 ~25.74 miles north of Lake City
  • Two-star Highway hotel
  • Free breakfast available
From£46
Average 3.0 /5 Read Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence in Florence
+1-888-906-6358
2123 West Lucas St., Florence, SC 29501 ~25.77 miles north of Lake City
  • 3 star Highway property
  • Check-in: 03:00 PM
From£63
Average 3.0 /5 Guest Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Florence in Florence
+1-888-749-6785
1912 Enterprise Dr., Florence, SC 29501 ~25.83 miles north of Lake City
  • Cheap Highway hotel
  • Check-in: 1:00pm
From£30
Poor 2.5 /5 Review Score Call BookMore Details
Florence Express Inn - Florence
+1-888-878-9982
3024 Tv Rd., Florence, SC 29501 ~27.77 miles north of Lake City
  • Economy Highway hotel

Next: See My Lake City Hotels with Pricing

Graph: Next 20 Days of Lake City Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Lake City, SC discounts available. The chart reflects the cheapest Lake City hotel for each day and each star rating category.

FAQs about hotels in Lake City

What are the most favored hotels in Lake City?

Comfort Inn & Suites Florence, Homewood Suites by Hilton Florence and Inn at the Crossroads are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels in Lake City?

Red Roof Inn Florence - Civic Center, Quality Inn & Suites and Quality Inn are the top 3 luxury hotels near Lake City city center.

What hotels are closest to the city center of Lake City?

Inn at the Crossroads, Days Inn by Wyndham Lake City, and Quality Inn & Suites are the properties closest to Lake City city center.

What are the best independent hotels in Lake City?

Inn at the Crossroads, Florence Express Inn and Fairview Inn Florence are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Lake City?

Towneplace Suites by Marriott Florence, Residence Inn Marriott Florence and Fairfield Inn & Suites by Marriott Florence I-20 are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Lake City?

Comfort Inn & Suites Florence, Quality Inn & Suites and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Lake City?

Staybridge Suites, Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IH and Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327, an I are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Recent traveler reviews of Lake City, SC

Below are reviews of the city of Lake City, SC from an actual visitor's perspective.

"Beautiful City"
Score 5.0 / 5

Beautiful city.

Joshua R., from 20-Jun-2024
"Enjoyed Visiting the Sites"
Score 4.0 / 5

Great memories, from my youth, enjoying visiting old and new sites.

Carroll M., from 14-Jan-2024
"Convenient Location"
Score 4.0 / 5

Everywhere was convenient to hotel.

Ishmal S., from 12-Jul-2023
"Great, Emerging City"
Score 4.0 / 5

The town has grown since the last time I visited. The shops were within walking distance. Every place we visited was very nice.

Cheryl H., from 10-Nov-2014
The average traveler rating of the city of Lake City, SC shown above is 4.3 out of 5 based on 4 reviews
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