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Lake City South Carolina Accommodations

Find the perfect hotel in Lake City using our hotel guide provided below. Find discounted hotel accommodations in or close to Lake City, SC for your personal leisure or group travel. Discover the most favored Lake City South Carolina hotel/motel rooms. Review the Lake City hotel list below to find the perfect lodging. We also have a map of the Lake City hotels. Coordinating a group? Get Lake City Group Hotel Rates

The Lake City center is approximately 12 miles northeast of Williamsburg County Airport and 14 miles north of Kingstree Amtrak Station.

Lake City Hotels/Motels & Accommodations

Inn at the Crossroads : 128 West Main St.
+1-888-389-4121
128 West Main St., Lake City, SC 29560
  • Low-priced Downtown hotel
  • 57 rooms in hotel
From£86
Very good 4.0 /5 Guest Reviews Call BookMore Details
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Days Inn by Wyndham Lake City
+1-888-675-2083
170 South Ron Mcnair Blvd., Lake City, SC 29560
  • Low-priced Downtown property
  • Free comp. breakfast
From£47
Average 3.5 /5 Review Score Call BookMore Details
Quality Inn & Suites : 202 North Ron Mcnair Blvd.
+1-800-716-8490
202 North Ron Mcnair Blvd., Lake City, SC 29560
  • Mid-scale property
  • Check in time: 15:00
From£63
Very good 4.0 /5 Latest Reviews Call BookMore Details
Quality Inn - Kingstree
+1-800-805-5223
1610 North Longstreet St., Kingstree, SC 29556 ~13.47 miles south of Lake City
  • Affordable Highway hotel
  • Check in: 15:00
From£63
Very good 4.0 /5 Recent Reviews Call BookMore Details
Days Inn by Wyndham Turbeville
+1-888-965-1860
7835 Myrtle Beach Highway, Gable, SC 29051 ~20.05 miles west of Lake City
  • Low Cost hotel
  • Check in: 12:00 PM
From£47
Poor 2.0 /5 Read Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76 in Florence
+1-888-788-5576
3783a West Palmetto St., Florence, SC 29501 ~21.41 miles north of Lake City
  • Two-star Highway property
  • Check in: 2pm
From£46
Terrible 1.0 /5 Review Score Call BookMore Details
Days Inn Florence - Florence
+1-888-897-9207
3783 West Palmetto St. I 95, Florence, SC 29501 ~21.42 miles north of Lake City
  • 2 star Highway property
  • Hotel has 120 rooms
Travelodge by Wyndham Florence : 1084 Oregon Coast Highway
+1-888-311-4278
1084 Oregon Coast Highway, Florence, OR 97439 ~21.49 miles north of Lake City
  • Cheap property
From£78
Average 3.0 /5 Guest Reviews Call BookMore Details
Super 8 by Wyndham Florence SC I-95 North / Hwy 76
+1-888-469-4795
3783a West Palmetto St., Florence, SC 29502 ~21.49 miles north of Lake City
  • Low-priced Highway property
  • Comp. Breakfast
From£47
Terrible 1.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites Florence : 527 Woody Jones Blvd.
+1-888-734-9421
527 Woody Jones Blvd., Sc 554, SC 29501 ~22.63 miles north of Lake City
  • 3-star Suburban hotel
  • 3 floors in hotel
From£63
Very good 4.5 /5 Recent Reviews Call BookMore Details
Fairfield Inn & Suites by Marriott Florence I-20 : 501 Woody Jones Blvd.
+1-888-841-5292
501 Woody Jones Blvd., Florence, SC 29501 ~22.66 miles north of Lake City
  • Mid-scale Convention Center property
  • Fitness center on property
From£78
Average 3.0 /5 Read Reviews Call BookMore Details
Home2 Suites by Hilton Florence, SC - Florence
+1-888-455-5160
900 Woody Jones Blvd., Florence, SC 29501 ~22.71 miles north of Lake City
  • Mid-scale Convention Center hotel
  • Hotel has 83 rooms
From£70
Very good 4.0 /5 Review Score Call BookMore Details
Towneplace Suites by Marriott Florence in Florence
+1-888-965-8297
2650 Hospitality Blvd., Florence, SC 29501 ~22.79 miles north of Lake City
  • 3-star Suburban property
  • 89 rooms in property
From£74
Very good 4.0 /5 Recent Reviews Call BookMore Details
Springhill Suites
+1-888-906-6358
2670 Hospitality Blvd., Florence, SC 29501 ~22.80 miles north of Lake City
  • Mid-scale Convention Center property
  • Free comp. breakfast
From£63
Average 3.0 /5 Read Reviews Call BookMore Details
Accident - Florence
+1-888-749-6785
Florence Sc Usa, Florence, SC 29464 ~22.83 miles north of Lake City
  • 3-star hotel
From£243
Average 3.0 /5 Guest Reviews Call BookMore Details
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Residence Inn Marriott Florence in Florence
+1-888-878-9982
2660 Hospitality Blvd., Florence, SC 29501 ~22.85 miles north of Lake City
  • Three Star Suburban hotel
  • 94 rooms in property
From£74
Very good 4.0 /5 Latest Reviews Call BookMore Details
Staybridge Suites
+1-888-389-4485
150 Westpark Dr., Florence, SC 29501 ~22.87 miles north of Lake City
  • 3-star Convention Center property
  • Has environment-friendly policy See more
From£105
Very good 4.0 /5 Latest Reviews Call BookMore Details
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an I - Florence
+1-888-389-4121
3440 West Radio Dr., Florence, SC 29501 ~22.87 miles north of Lake City
  • Three Star Convention Center hotel
  • Fitness + Health Center
From£75
Very good 4.0 /5 Reviews Call BookMore Details
Red Roof Inn Florence - Civic Center
+1-888-675-2083
2690 David Mcleod Blvd., Florence, SC 29501 ~22.89 miles north of Lake City
  • Luxury 5-star Highway property
  • Airport shuttle provided
From£48
Average 3.0 /5 Review Score Call BookMore Details
Hyatt Place Florence Downtown : 100 East Evans St.
+1-800-716-8490
100 East Evans St., Florence, SC 29501 ~22.95 miles north of Lake City
  • High-end property
  • Check in time: 15:00
From£127
Very good 4.0 /5 Review Score Call BookMore Details
Hyatt Place Florence Downtown
+1-800-805-5223
100 East Evans St., Florence, SC 29505 ~22.96 miles north of Lake City
  • Three Star Downtown hotel
  • Check in time: 3:00
From£98
Very good 4.0 /5 Latest Reviews Call BookMore Details
Hotel Florence, Tapestry Collection by Hilton in Florence
+1-888-965-1860
126 West Evans St., Florence, SC 29501 ~22.97 miles north of Lake City
  • 3 star Downtown property
  • Check in time: 4:00pm
From£90
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Homewood Suites by Hilton Florence
+1-888-788-5576
3450 West Radio Dr., Florence, SC 29501 ~22.98 miles north of Lake City
  • 3-star Convention Center property
  • Gym / Fitness Center Available
From£63
Very good 4.5 /5 Read Reviews Call BookMore Details
Courtyard by Marriott Florence - Florence
+1-888-897-9207
2680 Hospitality Blvd., Florence, SC 29501 ~22.99 miles north of Lake City
  • Affordable Convention Center property
  • Hotel has 3 floors
From£78
Average 3.0 /5 Recent Reviews Call BookMore Details
Hilton Garden Inn in Florence
+1-888-311-4278
2671 Hospitality Blvd., Florence, SC 29501 ~23.00 miles north of Lake City
  • Three Star Highway hotel
  • Check in: 3:00 pm
From£86
Very good 4.0 /5 Recent Reviews Call BookMore Details
Hampton Inn & Suites Florence Center
+1-888-469-4795
3000 West Radio Dr., Florence, SC 29501 ~23.14 miles north of Lake City
  • Midscale Convention Center property
  • 3 floors in property
From£86
Very good 4.0 /5 Review Score Call BookMore Details
Days Inn by Wyndham Florence Near Civic Center : 140 Dunbarton Dr.
+1-888-734-9421
140 Dunbarton Dr., Florence, SC 29501 ~23.21 miles north of Lake City
  • Cheap Convention Center property
  • Free comp. breakfast
From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Quality Inn & Suites Civic Center - Florence
+1-888-841-5292
150 Dunbarton Dr., Florence, SC 29501 ~23.24 miles north of Lake City
  • Cheap Highway property
  • Fitness center on property
From£47
Average 3.0 /5 Hotel Reviews Call BookMore Details
Rodeway Inn & Suites - Florence
+1-888-455-5160
181 West Lucas St., Florence, SC 29501 ~23.50 miles north of Lake City
  • Economy hotel
  • Check in: 3:00 PM
From£47
Average 3.0 /5 Review Score Call BookMore Details
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327, an I
+1-888-965-8297
2101 Florence Harllee Blvd., Florence, SC 29506 ~23.79 miles north of Lake City
  • Three Star Suburban hotel
  • Check in: 4:00 PM
From£74
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Best Western Inn : 1808 West Lucas St.
+1-888-906-6358
1808 West Lucas St., Florence, SC 29501 ~25.09 miles north of Lake City
  • Low Cost Highway property
  • Check-in time: 3:00 PM
From£46
Average 3.5 /5 Read Reviews Call BookMore Details
Baymont Inn & Suites Florence by Wyndham
+1-888-749-6785
1826 West Lucas St., Florence, SC 29501 ~25.11 miles north of Lake City
  • Two-star Highway hotel
  • 5 suites in hotel
Super 8 by Wyndham Florence : 1832 1 / 2 Lucas St.
+1-888-878-9982
1832 1 / 2 Lucas St., Florence, SC 29501 ~25.13 miles north of Lake City
  • Cheap Highway property
From£47
Average 3.0 /5 Reviews Call BookMore Details
Knights Inn Florence : 1834 West Lucas St.
+1-888-389-4485
1834 West Lucas St., Florence, SC 29501 ~25.17 miles north of Lake City
  • 2-star hotel
From£39
Poor 2.0 /5 Reviews Call BookMore Details
Fairview Inn Florence
+1-888-389-4121
1811 West Lucas St., Florence, SC 29501 ~25.21 miles north of Lake City
  • Cheap Highway property
  • Check-in time: 03:00
From£31
Poor 2.0 /5 Reviews Call BookMore Details
Clarion Inn & Suites - Florence
+1-888-675-2083
1819 Building a West Lucas St., Florence, SC 29501 ~25.33 miles north of Lake City
  • Three Star Highway property
  • Check-in time: 3:00
From£63
Average 3.0 /5 Review Score Call BookMore Details
Mainstay Suites Florence Sc : 1819 West Lucas St. Building B
+1-800-716-8490
1819 West Lucas St. Building B, Florence, SC 29501 ~25.33 miles north of Lake City
  • Low priced Highway property
  • Fitness center on property
From£47
Average 3.0 /5 Hotel Reviews Call BookMore Details
Motel 6 Florence, SC
+1-800-805-5223
2004 West Lucas St., Florence, SC 29501 ~25.36 miles north of Lake City
  • Low-priced Downtown property
  • Check in: 3pm
From£47
Average 3.0 /5 Latest Reviews Call BookMore Details
Park Inn by Radisson Florence Sc : 1729 Mandeville Rd.
+1-888-965-1860
1729 Mandeville Rd., Florence, SC 27407 ~25.39 miles north of Lake City
  • 3-star hotel
  • Check in: 15:00
From£71
Very good 4.0 /5 Review Score Call BookMore Details
Park Inn by Radisson : 1729 Mandeville Rd.
+1-888-788-5576
1729 Mandeville Rd., Florence, SC 29501 ~25.39 miles north of Lake City
  • Economical Highway property
  • 60 sleeping rooms in hotel
From£59
Average 3.0 /5 Reviews Call BookMore Details
Country Inn & Suites by Radisson, Florence, SC
+1-888-897-9207
1739 Mandeville Rd., Florence, SC 29501 ~25.43 miles north of Lake City
  • Affordable Highway property
  • Hotel has 3 floors
From£62
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Suburban Studios Florence I-95
+1-888-311-4278
1914 West Lucas St., Florence, SC 29501 ~25.48 miles north of Lake City
  • Cheap Highway property
  • 24 suites in hotel
From£33
Poor 2.0 /5 Reviews Call BookMore Details
Howard Johnson by Wyndham Florence
+1-888-469-4795
2038 West Lucas St., Florence, SC 29501 ~25.49 miles north of Lake City
  • Inexpensive Highway hotel
  • Check in time: 3:00PM
From£47
Poor 2.0 /5 Reviews Call BookMore Details
Hampton Inn & Suites Florence North : 1735 Stokes Rd.
+1-888-734-9421
1735 Stokes Rd., Florence, SC 29501 ~25.50 miles north of Lake City
  • Inexpensive Highway property
  • 6 conference rooms in property
From£82
Very good 4.0 /5 Hotel Reviews Call BookMore Details
Days Inn by Wyndham Florence/I-95 North
+1-888-841-5292
2111 West Lucas, Florence, SC 29501 ~25.61 miles north of Lake City
  • Cheap Highway property
  • Check in: 2pm
From£39
Average 3.5 /5 Latest Reviews Call BookMore Details
Comfort Suites Florence I-95
+1-888-455-5160
2120 West Lucas St., Florence, SC 29501 ~25.65 miles north of Lake City
  • Affordable Highway hotel
  • Comp. Breakfast
From£63
Very good 4.0 /5 Read Reviews Call BookMore Details
Tru by Hilton Florence I-95 in Florence
+1-888-965-8297
2140 West Lucas St., Florence, SC 29501 ~25.70 miles north of Lake City
  • Three Star hotel
  • 5 floors in hotel
From£63
Very good 4.0 /5 Reviews Call BookMore Details
Sleep Inn Florence North : 1833 Florence Park Dr.
+1-888-906-6358
1833 Florence Park Dr., Florence, SC 29501 ~25.74 miles north of Lake City
  • Low-priced Highway hotel
  • Comp. Breakfast
From£46
Average 3.0 /5 Review Score Call BookMore Details
La Quinta Inn & Suites by Wyndham Florence in Florence
+1-888-749-6785
2123 West Lucas St., Florence, SC 29501 ~25.77 miles north of Lake City
  • Mid-scale Highway hotel
  • 84 rooms in property
From£63
Average 3.0 /5 Hotel Reviews Call BookMore Details
Microtel Inn & Suites by Wyndham Florence
+1-888-878-9982
1912 Enterprise Dr., Florence, SC 29501 ~25.83 miles north of Lake City
  • Economy Highway property
  • 83 rooms in hotel

Next: See My Lake City Hotels with Pricing

Graph: Next 20 Days of Lake City Hotel Prices

Rates shown are nightly rates before taxes and do not necessarily reflect all Lake City, SC discounts available. The chart reflects the cheapest Lake City hotel for each day and each star rating category.

FAQs about hotels in Lake City

What are the most favored hotels in Lake City?

Comfort Inn & Suites Florence, Homewood Suites by Hilton Florence and Inn at the Crossroads are the best rated hotels based on customer reviews in the last 365 days.

What are the top luxurious hotels in Lake City?

Red Roof Inn Florence - Civic Center, Hyatt Place Florence Downtown and Quality Inn & Suites are the top 3 luxury hotels near Lake City city center.

What hotels are closest to the city center of Lake City?

Inn at the Crossroads, Days Inn by Wyndham Lake City, and Quality Inn & Suites are the properties closest to Lake City city center.

What are the best independent hotels in Lake City?

Inn at the Crossroads, Fairview Inn Florence and Suburban Studios Florence I-95 are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Lake City?

Towneplace Suites by Marriott Florence, Residence Inn Marriott Florence and Fairfield Inn & Suites by Marriott Florence I-20 are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Lake City?

Comfort Inn & Suites Florence, Quality Inn & Suites and Quality Inn are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Lake City?

Staybridge Suites, Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr, an I and Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327, an I are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Recent traveler reviews of Lake City, SC

Below are reviews of the city of Lake City, SC from an actual visitor's perspective.

"Beautiful City"
Score 5.0 / 5

Beautiful city.

Joshua R., from 20-Jun-2024
"Enjoyed Visiting the Sites"
Score 4.0 / 5

Great memories, from my youth, enjoying visiting old and new sites.

Carroll M., from 14-Jan-2024
"Convenient Location"
Score 4.0 / 5

Everywhere was convenient to hotel.

Ishmal S., from 12-Jul-2023
"Great, Emerging City"
Score 4.0 / 5

The town has grown since the last time I visited. The shops were within walking distance. Every place we visited was very nice.

Cheryl H., from 10-Nov-2014
The average traveler rating of the city of Lake City, SC shown above is 4.3 out of 5 based on 4 reviews
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