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Charleston Missouri Hotels & Motels

Find the perfect hotel in Charleston using our hotel guide provided below. Find discounted hotel accommodations in or close to Charleston, MO for your upcoming individual or group travel. Discover the most popular Charleston, Missouri hotel and motel rooms. Browse the Charleston area hotels to find the perfect lodging! Please use the provided map of the Charleston hotels. Coordinating a group? Get Charleston Group Hotel Rates

Charleston Hotels/Accommodations

Super 8 by Wyndham Charleston/Sikeston East MO : 310 South Story
+1-888-389-4121
310 South Story, Charleston, MO 63834
  • 2 star Highway hotel
  • 7 suites in property
From$42
Average 3.5 /5 Reviews Call BookMore Details
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Quality Inn Charleston - Sikeston : 102 Drake St.
+1-888-675-2083
102 Drake St., Charleston, MO 63834
  • Cheap Highway property
  • Complimentary breakfast is offered
From$59
Average 3.0 /5 Read Reviews Call BookMore Details
Motel 6 Sikeston Mo
+1-800-716-8490
110 South Interstate Dr., SIKESTON, MO 63801 ~11.02 miles west of Charleston
  • Economy hotel
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Best Western Plus Sikeston - Sikeston
+1-800-805-5223
120 South Interstate Dr., Sikeston, MO 63801 ~11.05 miles west of Charleston
  • 2-star Highway property
  • Hotel has 55 rooms
From$43
Very Good 4.0 /5 Read Reviews Call BookMore Details
Days Inn and Suites by Wyndham Sikeston
+1-888-965-1860
220 South Interstate Dr., Sikeston, MO 63801 ~11.09 miles west of Charleston
  • Cheap property
  • Gym is available on property
From$60
Average 3.0 /5 Review Score Call BookMore Details
Quality Inn Cairo I-57 - Cairo
+1-888-788-5576
13201 Kessler Rd., Cairo, IL 62914 ~11.20 miles northeast of Charleston
  • Mid-scale Highway hotel
  • 2 floors in property
Super 8 by Wyndham Sikeston/Miner Area
+1-888-897-9207
2609 East Malone, Sikeston, MO 63801 ~11.36 miles west of Charleston
  • Cheap Convention Center hotel
  • Check in: 01:00
From$60
Average 3.0 /5 Reviews Call BookMore Details
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) - Sikeston
+1-888-311-4278
100 Matthews Lane, Sikeston, MO 63801 ~11.37 miles west of Charleston
  • Midscale Highway hotel
  • 2 floors in property
From$80
Very Good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn
+1-888-469-4795
109 Matthews Lane, Sikeston, MO 63801 ~11.40 miles west of Charleston
  • Midscale Highway hotel
  • 64 rooms in property
From$85
Average 3.0 /5 Recent Reviews Call BookMore Details
Drury Inn & Suites Sikeston
+1-888-734-9421
2608 East Malone Ave., Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Affordable Highway property
  • 5 floors in property
From$104
Very Good 4.5 /5 Latest Reviews Call BookMore Details
Pear Tree Inn Sikeston - Sikeston
+1-888-841-5292
2602 East Malone, Sikeston, MO 63801 ~11.45 miles west of Charleston
  • Midscale Suburban hotel
  • 2 suites in hotel
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Hampton Inn Sikeston : 1240 Commerce Dr.
+1-888-455-5160
1240 Commerce Dr., Sikeston, MO 63801 ~14.31 miles west of Charleston
  • 3-star Rural property
  • Hotel has 4 floors
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Sikeston An Ihg Hotel - Sikeston
+1-888-965-8297
115 Hospitality Dr., Sikeston, MO 63801 ~14.33 miles west of Charleston
  • Mid-scale Rural property
  • Gym / Fitness Center Available
From$80
Average 3.0 /5 Reviews Call BookMore Details
Americas Best Value Inn Ullin Mounds - Ullin
+1-888-906-6358
128 Cheekwood Lane, Ullin, IL 62992 ~25.98 miles north of Charleston
  • Economical hotel
  • Free complimentary breakfast
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Courtyard by Marriott Cape Girardeau Downtown - Cape Girardeau
+1-888-749-6785
400 Broadway St., Cape Girardeau, MO 63701 ~28.56 miles north of Charleston
  • Three Star Downtown property
  • Check-in: 3:00 pm
From$80
Very Good 4.0 /5 Review Score Call BookMore Details
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Candlewood Suites Cape Girardeau by IHG - Cape Girardeau
+1-888-878-9982
485 South Mount Auburn Rd., Cape Girardeau, MO 65703 ~28.61 miles northwest of Charleston
  • Cheap Highway hotel
  • Check in time: 3:00PM
From$69
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Hampton Inn Cape Girardeau I 55 East
+1-888-389-4485
207 South Mount Auburn Rd., Cape Girardeau, MO 63703 ~29.33 miles northwest of Charleston
  • 3-star Highway hotel
  • Check in time: 15:00
From$80
Excellent 5.0 /5 Recent Reviews Call BookMore Details
Victorian Inn & Suites : 3256 William St.
+1-888-389-4121
3256 William St., Cape Girardeau, MO 63703 ~29.40 miles northwest of Charleston
  • Mid-scale Golf Course property
  • 2 floors in property
From$79
Average 3.0 /5 Recent Reviews Call BookMore Details
Auburn Place Hotel & Suites : 3265 Williams St.
+1-888-675-2083
3265 Williams St., Cape Girardeau, MO 63702 ~29.41 miles northwest of Charleston
  • 3 star Highway hotel
  • Hotel has 2 floors
From$58
Very Good 4.5 /5 Hotel Reviews Call BookMore Details
Holiday Inn Express & Suites Cape Girardeau I 55
+1-800-716-8490
3253 William St., Cape Girardeau, MO 63701 ~29.43 miles northwest of Charleston
  • Affordable property
  • Gym is available on property
From$80
Very Good 4.5 /5 Review Score Call BookMore Details
Fairfield Inn & Suites Cape Girardeau in Cape Girardeay
+1-800-805-5223
433 Cape West Crossing, Cape Girardeay, MO 63703 ~29.46 miles northwest of Charleston
  • Three Star property
  • Hotel has 22 suites
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Pear Tree Inn Cape Girardeau West : 103 Cape West Pkwy.
+1-888-965-1860
103 Cape West Pkwy., Cape Girardeau, MO 63701 ~29.49 miles northwest of Charleston
  • Inexpensive hotel
  • Gym / Fitness Center Available
From$59
Average 3.0 /5 Review Score Call BookMore Details
Pear Tree Inn Cape Girardeau Medical Center
+1-888-788-5576
3248 William St., Cape Girardeau, MO 63701 ~29.50 miles northwest of Charleston
  • 2-star Highway property
  • 78 rooms in hotel
From$66
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Drury Suites Cape Girardeau in Cape Girardeau
+1-888-897-9207
3303 Campster Dr., Cape Girardeau, MO 63701 ~29.60 miles northwest of Charleston
  • 3 star Highway property
  • Check in: 3:00 PM
From$85
Very Good 4.5 /5 Review Score Call BookMore Details
Drury Plaza Hotel & Conference Center Cape Girardeau
+1-888-311-4278
3351 Percy Dr., Cape Girardeau, MO 63701 ~29.76 miles northwest of Charleston
  • Affordable hotel
  • Fitness + Health Center
From$59
Average 3.0 /5 Guest Reviews Call BookMore Details
Drury Lodge in Cape Girardeau
+1-888-469-4795
104 South Vantage Dr., Cape Girardeau, MO 63701 ~29.77 miles northwest of Charleston
  • Midscale Highway hotel
  • Complimentary breakfast is offered
From$80
Average 3.0 /5 Guest Reviews Call BookMore Details
Travel Inn
+1-888-734-9421
301 Route Ad, Marston, MO 63866 ~31.28 miles southwest of Charleston
  • Economy Highway hotel
  • Check in time: 3:00 PM
Travel Inn - Martson
+1-888-841-5292
301 State Highway Ad, Martson, MO 63866 ~31.46 miles southwest of Charleston
  • Two-star hotel
Red Roof Inn Marston : 501 South Outer Rd.
+1-888-455-5160
501 South Outer Rd., Marston, MO 63866 ~31.61 miles southwest of Charleston
  • Inexpensive property
  • 63 rooms in property
From$60
Average 3.0 /5 Recent Reviews Call BookMore Details
Quality Inn : 2011 North Kingshighway St.
+1-888-965-8297
2011 North Kingshighway St., Cape Girardeau, MO 63701 Website ~31.73 miles northwest of Charleston
  • Two-star property
  • Complimentary breakfast is offered
From$60
Very Good 4.0 /5 Recent Reviews Call BookMore Details
TRU by Hilton Cape Girardeau in Cape Girardeau
+1-888-906-6358
2520 Veterans Memorial Dr., Cape Girardeau, MO 63701 ~32.92 miles northwest of Charleston
  • Affordable Highway hotel
  • 90 rooms in property
From$80
Average 3.0 /5 Hotel Reviews Call BookMore Details
La Quinta Inn & Suites by Wyndham Jackson / Cape Girardeau
+1-888-749-6785
3003 South Old Orchard Rd., Jackson, MO 63755 ~33.46 miles northwest of Charleston
  • Midscale Highway hotel
  • Fitness / Gym is on-site
From$85
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Comfort Suites Jackson-Cape Girardeau - Jackson
+1-888-878-9982
2904 Old Orchard Rd., Jackson, MO 63755 Website ~33.57 miles northwest of Charleston
  • Midscale Highway hotel
  • Free comp. breakfast
From$65
Average 3.0 /5 Latest Reviews Call BookMore Details
Comfort Suites
+1-888-389-4485
2904 Old Orchard Rd., Jackson, 63755 United States ~33.57 miles northwest of Charleston
  • High-end Highway hotel
  • 64 suites in hotel
From$125
Average 3.0 /5 Read Reviews Call BookMore Details
Residence Inn by Marriott Paducah : 3900 Coleman Crossing Circle
+1-888-389-4121
3900 Coleman Crossing Circle, Paducah, KY 42001 ~34.97 miles east of Charleston
  • Affordable Suburban property
  • 3 floors in hotel
From$89
Very Good 4.0 /5 Hotel Reviews Call BookMore Details
Pear Tree Inn Paducah in Paducah
+1-888-675-2083
5006 Hinkleville Rd., Paducah, KY 42001 ~35.47 miles east of Charleston
  • Two star Suburban hotel
  • Free comp. breakfast
From$55
Very Good 4.0 /5 Latest Reviews Call BookMore Details
Econo Lodge Dexter
+1-800-716-8490
913 Outer Rd., Dexter, MO 63841 ~36.12 miles west of Charleston
  • Economical property
  • Check-in time: 11:00
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Harrah's Metropolis Hotel & Casino
+1-800-805-5223
100 East Front St., Metropolis, IL 62960 ~36.52 miles east of Charleston
  • High end hotel
  • Check-in time: 16:00
From$160
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Metropolis
+1-888-965-1860
203 East Front St., Metropolis, IL 62960 ~36.55 miles east of Charleston
  • Low Cost Riverfront property
  • Check-in time: 3:00PM
From$45
Average 3.0 /5 Hotel Reviews Call BookMore Details
Sleep Inn & Mainstay Suites
+1-888-788-5576
1111 Blue Heron Lane, Union City, TN 38261 ~36.64 miles southeast of Charleston
  • Low-priced Rural property
  • Hotel has an eco-friendly policy See more
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Travelodge by Wyndham Dexter
+1-888-897-9207
1608 West Business U.s. 60, Dexter, MO 63841 ~36.87 miles west of Charleston
  • Mid-scale hotel
From$67
Very Good 4.0 /5 Recent Reviews Call BookMore Details
 Econo Lodge Paducah West I-24 in Paducah
+1-888-311-4278
5120 Hinkleville Rd., Paducah, KY 42001 ~37.23 miles east of Charleston
  • Low-priced Airport hotel
  • 75 rooms in hotel
From$60
Average 3.0 /5 Latest Reviews Call BookMore Details
Drury Suites Paducah
+1-888-469-4795
2930 James Sanders Blvd., Paducah, KY 42001 ~37.34 miles east of Charleston
  • Mid-scale Suburban hotel
  • 138 rooms in hotel
From$99
Very Good 4.0 /5 Reviews Call BookMore Details
Quality Suites Paducah I-24 : 2880 James Sanders Blvd.
+1-888-734-9421
2880 James Sanders Blvd., Paducah, KY 42001 Website ~37.41 miles east of Charleston
  • Economy Highway hotel
  • Free breakfast
From$60
Average 3.0 /5 Guest Reviews Call BookMore Details
Sleep Inn Union City
+1-888-841-5292
1111b Blue Heron Lane, Union City, TN 38261 ~37.44 miles southeast of Charleston
  • 2-star Rural property
  • Check in time: 3:00 PM
From$78
Very Good 4.0 /5 Read Reviews Call BookMore Details
Comfort Inn & Suites near Six Flags : 960 West Pointe Court
+1-888-455-5160
960 West Pointe Court, Lithia Springs, GA 30122 Website ~37.46 miles east of Charleston
  • Midscale Downtown property
  • Gym is available on property
From$70
Very Good 4.0 /5 Review Score Call BookMore Details
Country Inn & Suites by Radisson, Paducah, KY in Paducah
+1-888-965-8297
145 Mcbride Lane, Paducah, KY 42001 ~37.46 miles east of Charleston
  • Midscale Highway property
  • Free complimentary breakfast
From$49
Very Good 4.0 /5 Recent Reviews Call BookMore Details
Baymont by Wyndham Paducah
+1-888-906-6358
5300 Old Cairo Rd., Paducah, KY 42001 ~37.50 miles east of Charleston
  • 3-star property
  • Check-in time: 15:00
Hotel 7 Inn : 5001 Hinkleville Rd.
+1-888-749-6785
5001 Hinkleville Rd., Paducah, KY 42001 ~37.51 miles east of Charleston
  • Cheap property
From$60
Average 3.0 /5 Reviews Call BookMore Details
Econo Lodge
+1-888-878-9982
1415 East 5th St., Metropolis, IL 62960 ~37.60 miles east of Charleston
  • Two-star hotel
From$60
Not Good 1.0 /5 Read Reviews Call BookMore Details

Next: See My Charleston Hotels with Pricing

Graph of Charleston, MO Hotel Prices for Next 20 Days

Rates shown are nightly rates before taxes and do not necessarily reflect all Charleston, MO discounts available. The chart reflects the cheapest Charleston hotel for each day and each star rating category.

FAQs about hotels in Charleston

What are the most favored hotels in Charleston?

Hampton Inn Cape Girardeau I 55 East, Drury Inn & Suites Sikeston and Auburn Place Hotel & Suites are the best rated hotels based on customer reviews in the last 365 days.

What are the most luxurious hotels in Charleston?

Comfort Suites, Harrah's Metropolis Hotel & Casino and Quality Inn Cairo I-57 are the top 3 luxury hotels near Charleston city center.

What hotels are closest to the city center of Charleston?

Super 8 by Wyndham Charleston, Quality Inn Charleston - Sikeston, and Motel 6 Sikeston Mo are the properties closest to Charleston city center.

How much does a cheap hotel in Charleston cost per night?

In the last year, a 2 star hotel in Charleston can be as cheap as $69.99 per night. (based on HotelPlanner prices)

How much does a 3 star hotel in Charleston cost per night?

In the last year, the average 3 star hotel in Charleston has been $54.99 per night. (based on HotelPlanner prices)

What are the best independent hotels in Charleston?

Auburn Place Hotel & Suites, Drury Suites Cape Girardeau and Travel Inn & Suites - Sikeston are the best rated independent hotels (not part of a big brand).

What are the most popular Marriott hotels in Charleston?

Courtyard by Marriott Cape Girardeau Downtown, Residence Inn by Marriott Paducah and Fairfield Inn & Suites Cape Girardeau are the best rated Marriott/Starwood branded hotels (based on customer reviews score).

What are the best Choice Hotels branded hotels in Charleston?

Quality Inn, Sleep Inn Union City and Comfort Inn & Suites near Six Flags are the best rated Choice Hotels branded hotels (based on HotelPlanner reviews score).

What are the best IHG hotels in Charleston?

Holiday Inn Express & Suites Cape Girardeau I 55, Candlewood Suites Cape Girardeau by IHG and Holiday Inn Express & Suites Sikeston An Ihg Hotel are the best rated Intercontinental Hotel Group (IHG) branded hotels (based on user reviews score).

Recent traveler reviews of Charleston, MO

Below are reviews of the city of Charleston, MO from an actual visitor's perspective.

"Easily Accessible"
Score 5.0 / 5

Easily accessible.

Mamon T., from 07-Dec-2023
The average traveler rating of the city of Charleston, MO shown above is 5.0 out of 5 based on 1 reviews
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